GM-CSF increases airway smooth muscle cell connective tissue expression by inducing TGF-β receptors

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 284, Issue 3 28-3, 2003, Pages

  Chen, Gang ^a   Grotendorst, Gary ^b   Eichholtz, Thomas ^c   Khalil, Nasreen ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Airway remodeling; Airway smooth muscle cells; Connective tissue growth factor; Corticosteroids; Granulocyte macrophage colony stimulating factor; Irreversible airway obstruction; Phosphorylated Smad2; Transforming growth factor

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; DEXAMETHASONE; FIBRONECTIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECEPTOR SUBTYPE; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

AIRWAY; AIRWAY OBSTRUCTION; ANIMAL CELL; ARTICLE; ASTHMA; CONNECTIVE TISSUE; CONTROLLED STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; SYNTHESIS;

EID: 0037370778     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00091.2002     Document Type: Article

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