메뉴 건너뛰기




Volumn 103, Issue 9, 1999, Pages 1353-1361

Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

Author keywords

[No Author keywords available]

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1;

EID: 0033135134     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI6130     Document Type: Article
Times cited : (202)

References (39)
  • 1
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell, J.E., Jr. 1997. STATs and gene regulation. Science. 277:1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell J.E., Jr.1
  • 2
    • 0030765924 scopus 로고    scopus 로고
    • Jaks, STATs, cytokine signal transduction, and immunoregulation: Are we there yet?
    • O'Shea, J.J. 1997. Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet? Immunity. 7:1-11.
    • (1997) Immunity , vol.7 , pp. 1-11
    • O'Shea, J.J.1
  • 3
    • 0025037094 scopus 로고
    • Eosinophilic inflammation in asthma
    • Bousquet, J., et al. 1990. Eosinophilic inflammation in asthma. N. Engl. J. Med. 323:1033-1039.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1033-1039
    • Bousquet, J.1
  • 4
    • 0024491638 scopus 로고
    • Association of asthma with serum IgE levels and skin-test reactivity to allergens
    • Burrows, B., et al. 1989. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N. Engl. J. Med. 320:271-277.
    • (1989) N. Engl. J. Med. , vol.320 , pp. 271-277
    • Burrows, B.1
  • 5
    • 0028358985 scopus 로고
    • Association between atopy and variants of the β subunit of the high-affinity immunoglobulin E receptor
    • Shirakawa, T., et al. 1994. Association between atopy and variants of the β subunit of the high-affinity immunoglobulin E receptor. Nat. Genet. 7:125-130.
    • (1994) Nat. Genet. , vol.7 , pp. 125-130
    • Shirakawa, T.1
  • 6
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
    • Marsh, D.G., et al. 1994. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science. 264:1152-1156.
    • (1994) Science , vol.264 , pp. 1152-1156
    • Marsh, D.G.1
  • 7
    • 0001325237 scopus 로고    scopus 로고
    • The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor
    • Hershey, G.K. et al. 1997. The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N. Engl. J. Med. 337:1720-1725.
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1720-1725
    • Hershey, G.K.1
  • 8
    • 0026610142 scopus 로고
    • H2-like bronchoalveolar T-lymphocyte population in atopic asthma
    • H2-like bronchoalveolar T-lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298-304.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 298-304
    • Robinson, D.S.1
  • 9
    • 0029302202 scopus 로고
    • Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon γ) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects
    • Ying, S., Durham, S.R., Corrigan, C.J., Hamid, Q., and Kay, A.B. 1995. Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon γ) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am. J. Respir. Cell Mol. Biol. 12:477-487.
    • (1995) Am. J. Respir. Cell Mol. Biol. , vol.12 , pp. 477-487
    • Ying, S.1    Durham, S.R.2    Corrigan, C.J.3    Hamid, Q.4    Kay, A.B.5
  • 10
    • 0031154833 scopus 로고    scopus 로고
    • Reduced production of IL-12 and IL-12-dependent IFN-γ release in patients with allergic asthma
    • van der Pouw Kraan, T.C.T.M., et al. 1997. Reduced production of IL-12 and IL-12-dependent IFN-γ release in patients with allergic asthma. J. Immunol. 158:5560-5565.
    • (1997) J. Immunol. , vol.158 , pp. 5560-5565
    • Van Der Pouw Kraan, T.C.T.M.1
  • 11
    • 0031014668 scopus 로고    scopus 로고
    • The inverse association between tuberculin responses and atopic disorders
    • Shirakawa, T., Enomoto, T., Shimazu, S., and Hopkin, J.M. 1997. The inverse association between tuberculin responses and atopic disorders. Science. 275:77-79.
    • (1997) Science , vol.275 , pp. 77-79
    • Shirakawa, T.1    Enomoto, T.2    Shimazu, S.3    Hopkin, J.M.4
  • 13
    • 0031965623 scopus 로고    scopus 로고
    • Control of epithelial immune-response genes and implications for airway immunity and inflammation
    • Holtzman, M.J., et al. 1998. Control of epithelial immune-response genes and implications for airway immunity and inflammation. Proc. Assoc. Am. Physicians. 110:1-11.
    • (1998) Proc. Assoc. Am. Physicians , vol.110 , pp. 1-11
    • Holtzman, M.J.1
  • 14
    • 0032526295 scopus 로고    scopus 로고
    • Patterns for RANTES secretion and intercellular adhesion molecule-1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo
    • Taguchi, M., et al. 1998. Patterns for RANTES secretion and intercellular adhesion molecule-1 expression mediate transepithelial T cell traffic based on analyses in vitro and in vivo. J. Exp. Med. 187:1927-1940.
    • (1998) J. Exp. Med. , vol.187 , pp. 1927-1940
    • Taguchi, M.1
  • 15
    • 0028362627 scopus 로고
    • Selective interaction of a subset of interferon-γ response element binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells
    • Look, D.C., Pelletier, M.R., and Holtzman, M.J. 1994. Selective interaction of a subset of interferon-γ response element binding proteins with the intercellular adhesion molecule-1 (ICAM-1) gene promoter controls the pattern of expression on epithelial cells. J. Biol. Chem. 269:8952-8958.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8952-8958
    • Look, D.C.1    Pelletier, M.R.2    Holtzman, M.J.3
  • 17
    • 0030712994 scopus 로고    scopus 로고
    • Targeted inhibition of interferon-γ-dependent ICAM-1 expression using dominant-negative Stat1
    • Walter, M.J., Look, D.C., Tidwell, R.M., Roswit, W.T., and Holtzman, M.J. 1997. Targeted inhibition of interferon-γ-dependent ICAM-1 expression using dominant-negative Stat1. J. Biol. Chem. 272:28582-28589.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28582-28589
    • Walter, M.J.1    Look, D.C.2    Tidwell, R.M.3    Roswit, W.T.4    Holtzman, M.J.5
  • 18
    • 0032432076 scopus 로고    scopus 로고
    • Direct suppression of Stat1 function during adenoviral infection
    • Look, D.C., et al. 1998. Direct suppression of Stat1 function during adenoviral infection. Immunity. 9:871-880.
    • (1998) Immunity , vol.9 , pp. 871-880
    • Look, D.C.1
  • 19
    • 0028079329 scopus 로고
    • Selective differences in vascular endothelial vs. airway epithelial-T cell adhesion mechanisms
    • Nakajima, S., et al. 1994. Selective differences in vascular endothelial vs. airway epithelial-T cell adhesion mechanisms. Am. J. Physiol. 267:L422-L432.
    • (1994) Am. J. Physiol. , vol.267
    • Nakajima, S.1
  • 21
    • 0002373303 scopus 로고    scopus 로고
    • Regulation of epithelial-leukocyte interaction and epithelial immune-response genes
    • W. Busse and S. Holgate, editors. Blackwell Scientific. Cambridge, MA. In press
    • Holtzman, M.J., Castro, M., Look, D.C., O'Sullivan, M., and Walter, M.J. 1999. Regulation of epithelial-leukocyte interaction and epithelial immune-response genes. In Asthma and rhinitis. W. Busse and S. Holgate, editors. Blackwell Scientific. Cambridge, MA. In press.
    • (1999) Asthma and Rhinitis
    • Holtzman, M.J.1    Castro, M.2    Look, D.C.3    O'Sullivan, M.4    Walter, M.J.5
  • 22
    • 0026777610 scopus 로고
    • Selective induction of intercellular adhesion molecule-1 by interferon-γ in human airway epithelial cells
    • Look, D.C., Keller, B.T., Rapp, S.R., and Holtzman, M.J. 1992. Selective induction of intercellular adhesion molecule-1 by interferon-γ in human airway epithelial cells. Am. J. Physiol. 263:L79-L87.
    • (1992) Am. J. Physiol. , vol.263
    • Look, D.C.1    Keller, B.T.2    Rapp, S.R.3    Holtzman, M.J.4
  • 23
    • 0000401540 scopus 로고    scopus 로고
    • Autoamplification of Stat1-dependent gene expression
    • Abstr.
    • Sampath, D., et al. 1998. Autoamplification of Stat1-dependent gene expression. FASEB J. 12:A1390. (Abstr.)
    • (1998) FASEB J. , vol.12
    • Sampath, D.1
  • 24
    • 33749106875 scopus 로고    scopus 로고
    • Induction of epithelial immune-response genes in a mouse model of viral bronchitis and hyperreactivity
    • Walter, M.J., Kajiwara, N., Sampath, D., Rucker, J., and Holtzman, M.J. 1998. Induction of epithelial immune-response genes in a mouse model of viral bronchitis and hyperreactivity. FASEB J. 12:1453.
    • (1998) FASEB J. , vol.12 , pp. 1453
    • Walter, M.J.1    Kajiwara, N.2    Sampath, D.3    Rucker, J.4    Holtzman, M.J.5
  • 25
    • 0033545864 scopus 로고    scopus 로고
    • Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization
    • In press
    • Koga, T., et al. 1999. Virus-inducible expression of a host chemokine gene relies on replication-linked mRNA stabilization. Proc. Natl. Acad. Sci. USA. In press.
    • (1999) Proc. Natl. Acad. Sci. USA
    • Koga, T.1
  • 27
    • 0023145958 scopus 로고
    • Enhanced 5-lipoxygenase activity in pulmonary macrophages compared to monocytes from normal subjects
    • Bigby, T.D., and Holtzman, M.J. 1987. Enhanced 5-lipoxygenase activity in pulmonary macrophages compared to monocytes from normal subjects. J. Immunol. 138:1546-1550.
    • (1987) J. Immunol. , vol.138 , pp. 1546-1550
    • Bigby, T.D.1    Holtzman, M.J.2
  • 28
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • Kaptein, A., Paillard, V., and Saunders, M. 1996. Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J. Biol. Chem. 271:5961-5964.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 29
    • 0026514960 scopus 로고
    • Cytokines in symptomatic asthma airways
    • Broide, D.H., et al. 1992. Cytokines in symptomatic asthma airways. J. Allergy Clin. Immunol. 89:958-967.
    • (1992) J. Allergy Clin. Immunol. , vol.89 , pp. 958-967
    • Broide, D.H.1
  • 30
    • 0026903531 scopus 로고
    • c-fos proto-oncogene expression in bronchial biopsies of asthmatics
    • Demoly, P., et al. 1992. c-fos proto-oncogene expression in bronchial biopsies of asthmatics. Am. J. Respir. Cell Mol. Biol. 7:128-133.
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 128-133
    • Demoly, P.1
  • 31
    • 0028881859 scopus 로고
    • Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma
    • Adcock, I.M., Lane, S.J., Brown, C.R., Lee, T.H., and Barnes, P.J. 1995. Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma. J. Exp. Med. 182:1951-1958.
    • (1995) J. Exp. Med. , vol.182 , pp. 1951-1958
    • Adcock, I.M.1    Lane, S.J.2    Brown, C.R.3    Lee, T.H.4    Barnes, P.J.5
  • 32
    • 0030865879 scopus 로고    scopus 로고
    • Interferon γ and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators
    • Guo, F.H., et al. 1997. Interferon γ and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators. J. Clin. Invest. 100:829-838.
    • (1997) J. Clin. Invest. , vol.100 , pp. 829-838
    • Guo, F.H.1
  • 33
    • 0028348307 scopus 로고
    • Requirement for transcription factor IRF-1 in NO synthase induction in macrophages
    • Kamijo, R., et al. 1994. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science. 263:1612-1615.
    • (1994) Science , vol.263 , pp. 1612-1615
    • Kamijo, R.1
  • 34
    • 0027379178 scopus 로고
    • Induction of nitric oxide synthase in asthma
    • Hamid, Q., et al. 1993. Induction of nitric oxide synthase in asthma. Lancet. 342:1510-1513.
    • (1993) Lancet , vol.342 , pp. 1510-1513
    • Hamid, Q.1
  • 35
    • 0030896404 scopus 로고    scopus 로고
    • Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
    • Su, W.-C.S., et al. 1997. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature. 386:288-292.
    • (1997) Nature , vol.386 , pp. 288-292
    • Su, W.-C.S.1
  • 36
    • 0029742102 scopus 로고    scopus 로고
    • Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1
    • Shuai, K., Liao, J.Y., and Song, M.M. 1996. Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1. Mol. Cell. Biol. 16:4932-4941.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4932-4941
    • Shuai, K.1    Liao, J.Y.2    Song, M.M.3
  • 37
    • 0032473555 scopus 로고    scopus 로고
    • Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway
    • Miller, D.M., et al. 1998. Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway. J. Exp. Med. 187:675-683.
    • (1998) J. Exp. Med. , vol.187 , pp. 675-683
    • Miller, D.M.1
  • 38
    • 0032563244 scopus 로고    scopus 로고
    • A viral mechanism for inhibition of cellular phosphatase calcineurin
    • Mishkin, J.E., Abrams, C.C., Goatley, L.C., and Dixon, L.K. 1998. A viral mechanism for inhibition of cellular phosphatase calcineurin. Science. 281:562-565.
    • (1998) Science , vol.281 , pp. 562-565
    • Mishkin, J.E.1    Abrams, C.C.2    Goatley, L.C.3    Dixon, L.K.4
  • 39
    • 0005909165 scopus 로고    scopus 로고
    • Mechanisms for cytokine regulation of β-chemokine expression in airway epithelial cells
    • Abstr.
    • Koga, T., Look, D.C., Tidwell, R.M., and Holtzman, M.J. 1998. Mechanisms for cytokine regulation of β-chemokine expression in airway epithelial cells. Am. J. Respir. Crit. Care Med. 157:A744. (Abstr.)
    • (1998) Am. J. Respir. Crit. Care Med. , vol.157
    • Koga, T.1    Look, D.C.2    Tidwell, R.M.3    Holtzman, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.