메뉴 건너뛰기




Volumn 166, Issue 9, 2002, Pages 1269-1281

Three-dimensional mapping of sensory innervation with substance P in porcine bronchial mucosa: Comparison with human airways

Author keywords

Afferent pathways; Bronchi innervation; Human physiology; Neurogenic inflammation; Neuropeptides; Substance P; Swine physiology

Indexed keywords

1,1' DIDODECYL 3,3,3',3' TETRAMETHYLINDOCARBOCYANINE PERCHLORATE; CALCITONIN GENE RELATED PEPTIDE; CARBOCYANINE; GENE PRODUCT; NEUROPEPTIDE; SUBSTANCE P; UNCLASSIFIED DRUG;

EID: 0036840479     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.2112018     Document Type: Article
Times cited : (61)

References (54)
  • 1
    • 0021299663 scopus 로고
    • Afferent vagal C fibre innervation of the lungs and airways and its functional significance
    • Coleridge JC, Coleridge HM. Afferent vagal C fibre innervation of the lungs and airways and its functional significance. Rev Physiol Biochem Pharmacol 1984;99:1-110.
    • (1984) Rev Physiol Biochem Pharmacol , vol.99 , pp. 1-110
    • Coleridge, J.C.1    Coleridge, H.M.2
  • 3
    • 0035126782 scopus 로고    scopus 로고
    • Neurogenic inflammation in the airways
    • Barnes PJ. Neurogenic inflammation in the airways. Respir Physiol 2001;125:145-154.
    • (2001) Respir Physiol , vol.125 , pp. 145-154
    • Barnes, P.J.1
  • 4
    • 0026668155 scopus 로고
    • Substance P-immunoreactive sensory axons in the rat respiratory tract: A quantitative study of their distribution and role in neurogenic inflammation
    • Baluk P, Nadel JA, McDonald DM. Substance P-immunoreactive sensory axons in the rat respiratory tract: A quantitative study of their distribution and role in neurogenic inflammation. J Comp Neurol 1992:319:586-598.
    • (1992) J Comp Neurol , vol.319 , pp. 586-598
    • Baluk, P.1    Nadel, J.A.2    McDonald, D.M.3
  • 5
    • 0028126022 scopus 로고
    • Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli
    • McDonald DM. Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli. Am J Physiol 1994:266:L61-L83.
    • (1994) Am J Physiol , vol.266
    • McDonald, D.M.1
  • 6
    • 0021039421 scopus 로고
    • Effects and distribution of vagal capsaicin-sensitive substance P neurons with special reference to the trachea and lungs
    • Lundberg JM, Brodin E, Saria A. Effects and distribution of vagal capsaicin-sensitive substance P neurons with special reference to the trachea and lungs. Acta Physiol Scand 1983;119:243-252.
    • (1983) Acta Physiol Scand , vol.119 , pp. 243-252
    • Lundberg, J.M.1    Brodin, E.2    Saria, A.3
  • 8
    • 0021705762 scopus 로고
    • Potent stimulation of glycoprotein secretion in canine trachea by substance P
    • Coles SJ, Neill KH, Reid LM. Potent stimulation of glycoprotein secretion in canine trachea by substance P. J Appl Physiol 1984;57:1323-1327.
    • (1984) J Appl Physiol , vol.57 , pp. 1323-1327
    • Coles, S.J.1    Neill, K.H.2    Reid, L.M.3
  • 9
    • 0028961828 scopus 로고
    • NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea
    • Baluk P, Bertrand C, Geppetti P, McDonald DM, Nadel JA. NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea. Am J Physiol 1995;268:L263-L69.
    • (1995) Am J Physiol , vol.268
    • Baluk, P.1    Bertrand, C.2    Geppetti, P.3    McDonald, D.M.4    Nadel, J.A.5
  • 10
    • 0033756629 scopus 로고    scopus 로고
    • Neuropeptide-induced chemotaxis of eosinophils in pulmonary diseases
    • Dunzendorfer S, Wiedermann CJ. Neuropeptide-induced chemotaxis of eosinophils in pulmonary diseases. Ann Med 2000;32:429-439.
    • (2000) Ann Med , vol.32 , pp. 429-439
    • Dunzendorfer, S.1    Wiedermann, C.J.2
  • 11
    • 0020560694 scopus 로고
    • Capsaicin-induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants
    • Lundberg JM, Saria A. Capsaicin-induced desensitization of airway mucosa to cigarette smoke, mechanical and chemical irritants. Nature 1983;302:251-253.
    • (1983) Nature , vol.302 , pp. 251-253
    • Lundberg, J.M.1    Saria, A.2
  • 12
    • 0024571281 scopus 로고
    • Vagally mediated vasodilatation by motor and sensory nerves in the tracheal and bronchial circulation of the pig
    • Matran R, Alving K, Martling CR, Lacroix JS, Lundberg JM. Vagally mediated vasodilatation by motor and sensory nerves in the tracheal and bronchial circulation of the pig. Acta Physiol Scand 1989;135:29-37.
    • (1989) Acta Physiol Scand , vol.135 , pp. 29-37
    • Matran, R.1    Alving, K.2    Martling, C.R.3    Lacroix, J.S.4    Lundberg, J.M.5
  • 14
    • 0022578896 scopus 로고
    • Asthma as an axon reflex
    • Barnes. Asthma as an axon reflex. Lancet 1986;1:242-245.
    • (1986) Lancet , vol.1 , pp. 242-245
    • Barnes1
  • 15
    • 0028947970 scopus 로고
    • Neurogenic inflammation in human airways: Is it important
    • Joos GF, Germonpre PR, Pauwels RA. Neurogenic inflammation in human airways: Is it important [editoriall? Thorax 1995;50:217-219.
    • (1995) Thorax , vol.50 , pp. 217-219
    • Joos, G.F.1    Germonpre, P.R.2    Pauwels, R.A.3
  • 16
    • 0021365012 scopus 로고
    • Substance P-immunoreactive sensory nerves in the lower respiratory tract of various animals including man
    • Lundberg JM, Hokfelt T, Martling CR, Cuello C. Substance P-immunoreactive sensory nerves in the lower respiratory tract of various animals including man. Cell Tissue Res 1984;235:256-261.
    • (1984) Cell Tissue Res , vol.235 , pp. 256-261
    • Lundberg, J.M.1    Hokfelt, T.2    Martling, C.R.3    Cuello, C.4
  • 17
    • 0025807920 scopus 로고
    • Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics
    • Ollerenshaw SL, Jarvis D, Sullivan CE, Woolcock AJ. Substance P immunoreactive nerves in airways from asthmatics and nonasthmatics. Eur Respir J 1991;4:673-682.
    • (1991) Eur Respir J , vol.4 , pp. 673-682
    • Ollerenshaw, S.L.1    Jarvis, D.2    Sullivan, C.E.3    Woolcock, A.J.4
  • 18
    • 0030935960 scopus 로고    scopus 로고
    • Structure and function of the adventitial and mucosal nerve plexuses of the bronchial tree in the developing lung
    • Sparrow MP. Weichselbaum M. Structure and function of the adventitial and mucosal nerve plexuses of the bronchial tree in the developing lung. Clin Exp Pharmacol Physiol 1997;24:261-268.
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , pp. 261-268
    • Sparrow, M.P.1    Weichselbaum, M.2
  • 19
    • 0025343101 scopus 로고
    • Origin and colocalization of CGRP- and SP-reactive nerves in cat airway epithelium
    • Dey RD, Altemus JB, Zervos I, Hoffpauir J. Origin and colocalization of CGRP- and SP-reactive nerves in cat airway epithelium. J Appl Physiol 1990;68:770-778.
    • (1990) J Appl Physiol , vol.68 , pp. 770-778
    • Dey, R.D.1    Altemus, J.B.2    Zervos, I.3    Hoffpauir, J.4
  • 20
    • 0023567226 scopus 로고
    • Dose-related effects of pharmacological mediators on tracheal vascular resistance in dogs
    • Laitinen LA. Laitinen MA, Widdicombe JG. Dose-related effects of pharmacological mediators on tracheal vascular resistance in dogs. Br J Pharmacol 1987;92:703-709.
    • (1987) Br J Pharmacol , vol.92 , pp. 703-709
    • Laitinen, L.A.1    Laitinen, M.A.2    Widdicombe, J.G.3
  • 21
    • 0024315317 scopus 로고
    • Innervation of the guinea pig trachea: A quantitative morphological study of intrinsic neurons and extrinsic nerves
    • Baluk P. Gabella G. Innervation of the guinea pig trachea: A quantitative morphological study of intrinsic neurons and extrinsic nerves. J Comp Neurol 1989;285:117-132.
    • (1989) J Comp Neurol , vol.285 , pp. 117-132
    • Baluk, P.1    Gabella, G.2
  • 22
    • 0026766116 scopus 로고
    • The sensory and sympathetic innervation of guinea pig lung and trachea as studied retrograde neuronal tracing and double labeling immunohistochemistry
    • Kummer WA, Fischer A, Kurkowski R, Heym C, The sensory and sympathetic innervation of guinea pig lung and trachea as studied retrograde neuronal tracing and double labeling immunohistochemistry. Neuroscience 1992;49:715-737.
    • (1992) Neuroscience , vol.49 , pp. 715-737
    • Kummer, W.A.1    Fischer, A.2    Kurkowski, R.3    Heym, C.4
  • 23
    • 4243382209 scopus 로고
    • Relative density of substance P-immunoreactive (SP-IR) nerve fibres in tracheal epithelium of a range of species
    • Bowden JJ, Gibbins IL. Relative density of substance P-immunoreactive (SP-IR) nerve fibres in tracheal epithelium of a range of species [abstract]. FASEB J 1992;6:A1276.
    • (1992) FASEB J , vol.6
    • Bowden, J.J.1    Gibbins, I.L.2
  • 26
    • 0025484760 scopus 로고
    • Immunohistochemical localization of peptide-containing nerves in human airways: Age-related changes
    • Hislop AA, Wharton J, Allen KM, Polak JM, Haworth SG. Immunohistochemical localization of peptide-containing nerves in human airways: Age-related changes. Am J Respir Cell Mol Biol 1990;3:191-198.
    • (1990) Am J Respir Cell Mol Biol , vol.3 , pp. 191-198
    • Hislop, A.A.1    Wharton, J.2    Allen, K.M.3    Polak, J.M.4    Haworth, S.G.5
  • 27
    • 0027231467 scopus 로고
    • Peptide-containing nerve fibres in human airways: Distribution and coexistence pattern
    • Luts A, Uddman R, Alm P, Basterra J, Sundler F. Peptide-containing nerve fibres in human airways: Distribution and coexistence pattern. Int Arch Allergy Immunol 1993;101:52-60.
    • (1993) Int Arch Allergy Immunol , vol.101 , pp. 52-60
    • Luts, A.1    Uddman, R.2    Alm, P.3    Basterra, J.4    Sundler, F.5
  • 28
    • 0020602687 scopus 로고
    • Immunohistochemical demonstration of substance P in the lower respiratory tract of the rabbit and not of man
    • Laitinen LA, Laitinen A, Panula PA, Partanen M, Tervo K, Tervo T. Immunohistochemical demonstration of substance P in the lower respiratory tract of the rabbit and not of man. Thorax 1983;38:531-536.
    • (1983) Thorax , vol.38 , pp. 531-536
    • Laitinen, L.A.1    Laitinen, A.2    Panula, P.A.3    Partanen, M.4    Tervo, K.5    Tervo, T.6
  • 29
    • 0023064229 scopus 로고
    • Sensory nerves containing tachykinins and CGRP in the lower airways: Functional implications for bronchoconstriction, vasodilatation and protein extravasation
    • Martling CR. Sensory nerves containing tachykinins and CGRP in the lower airways: Functional implications for bronchoconstriction, vasodilatation and protein extravasation. Acta Physiol Scand Suppl 1987;563:1-57.
    • (1987) Acta Physiol Scand Suppl , vol.563 , pp. 1-57
    • Martling, C.R.1
  • 30
    • 0021073164 scopus 로고
    • Cigarette smoke-induced airway oedema due to activation of capsaicin-sensitive vagal afferents and substance P release
    • Lundberg JM, Martling CR, Saria A, Folkers K, Rosell S. Cigarette smoke-induced airway oedema due to activation of capsaicin-sensitive vagal afferents and substance P release. Neuroscience 1983;10:1361-1368.
    • (1983) Neuroscience , vol.10 , pp. 1361-1368
    • Lundberg, J.M.1    Martling, C.R.2    Saria, A.3    Folkers, K.4    Rosell, S.5
  • 32
    • 0032572565 scopus 로고    scopus 로고
    • Identification of motor neurons to the circular muscle of the guinea pig gastric corpus
    • Brookes SJ, Hennig G, Schemann M. Identification of motor neurons to the circular muscle of the guinea pig gastric corpus. J Comp Neurol 1998;397:268-280.
    • (1998) J Comp Neurol , vol.397 , pp. 268-280
    • Brookes, S.J.1    Hennig, G.2    Schemann, M.3
  • 33
    • 84965925133 scopus 로고
    • The development of the lungs
    • Flint JM. The development of the lungs. Am J Anat 1906;6:1-136.
    • (1906) Am J Anat , vol.6 , pp. 1-136
    • Flint, J.M.1
  • 34
    • 0033219810 scopus 로고    scopus 로고
    • A confocal microscopic study of the formation of ganglia in the airways of fetal pig lung
    • Weichselbaum M, Sparrow MP. A confocal microscopic study of the formation of ganglia in the airways of fetal pig lung. Am J Respir Cell Mol Biol 1999;21:607-620.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 607-620
    • Weichselbaum, M.1    Sparrow, M.P.2
  • 35
    • 0021827413 scopus 로고
    • Ultrastructural organisation of intraepithelial nerves in the human airway tract
    • Laitinen A. Ultrastructural organisation of intraepithelial nerves in the human airway tract. Thorax 1985;40:488-492.
    • (1985) Thorax , vol.40 , pp. 488-492
    • Laitinen, A.1
  • 37
    • 0035126917 scopus 로고    scopus 로고
    • Airway receptors
    • Widdicombe J. Airway receptors. Respir Physiol 2001;125:3-15.
    • (2001) Respir Physiol , vol.125 , pp. 3-15
    • Widdicombe, J.1
  • 38
    • 0032991515 scopus 로고    scopus 로고
    • Identification and substance P content of vagal afferent neurons innervating the epithelium of the guinea pig trachea
    • Hunter DD, Undem BJ. Identification and substance P content of vagal afferent neurons innervating the epithelium of the guinea pig trachea. Am J Respir Crit Care Med 1999;159:1943-1948.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 1943-1948
    • Hunter, D.D.1    Undem, B.J.2
  • 39
    • 0029843478 scopus 로고    scopus 로고
    • Interganglionic segregation of distinct vagal afferent fibre phenotypes in guinea-pig airways
    • Ricco MM, Kummer W, Biglari B, Myers AC, Undem BJ. Interganglionic segregation of distinct vagal afferent fibre phenotypes in guinea-pig airways. J Physiol (Lond) 1996;496:521-530.
    • (1996) J Physiol (Lond) , vol.496 , pp. 521-530
    • Ricco, M.M.1    Kummer, W.2    Biglari, B.3    Myers, A.C.4    Undem, B.J.5
  • 40
    • 0029811247 scopus 로고    scopus 로고
    • Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation
    • Fischer A, McGregor GP, Saria A, Philippin B, Kummer W. Induction of tachykinin gene and peptide expression in guinea pig nodose primary afferent neurons by allergic airway inflammation. J Clin Invest 1996;98:2284-2291.
    • (1996) J Clin Invest , vol.98 , pp. 2284-2291
    • Fischer, A.1    McGregor, G.P.2    Saria, A.3    Philippin, B.4    Kummer, W.5
  • 41
    • 0036082623 scopus 로고    scopus 로고
    • Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways
    • Myers AC, Kajekar R, Undem BJ. Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways. Am J Physiol 2002;282:L775-L781.
    • (2002) Am J Physiol , vol.282
    • Myers, A.C.1    Kajekar, R.2    Undem, B.J.3
  • 42
    • 0037090616 scopus 로고    scopus 로고
    • Expression of tachykinins in nonnociceptive vagal afferent neurons during respiratory viral infection in guinea pigs
    • Carr MJ, Hunter DD, Jacoby DB, Undem BJ. Expression of tachykinins in nonnociceptive vagal afferent neurons during respiratory viral infection in guinea pigs. Am J Respir Crit Care Med 2001;165:1071-1075.
    • (2001) Am J Respir Crit Care Med , vol.165 , pp. 1071-1075
    • Carr, M.J.1    Hunter, D.D.2    Jacoby, D.B.3    Undem, B.J.4
  • 43
    • 0034089114 scopus 로고    scopus 로고
    • Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons
    • Hunter DD, Myers AC, Undem BJ. Nerve growth factor-induced phenotypic switch in guinea pig airway sensory neurons. Am J Respir Crit Care Med 2000;161:1985-1990.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1985-1990
    • Hunter, D.D.1    Myers, A.C.2    Undem, B.J.3
  • 44
    • 0034830805 scopus 로고    scopus 로고
    • Inflammation-induced plasticity of the afferent innervation of the airways
    • Carr MJ, Undem BJ. Inflammation-induced plasticity of the afferent innervation of the airways. Environ Health Perspect 2001;109:567-571.
    • (2001) Environ Health Perspect , vol.109 , pp. 567-571
    • Carr, M.J.1    Undem, B.J.2
  • 46
    • 0025960070 scopus 로고
    • Pathways of substance P stimulation of canine tracheal ciliary beat frequency
    • Wong LB, Miller IF, Yeates DB. Pathways of substance P stimulation of canine tracheal ciliary beat frequency. J Appl Physiol 1991;70:267-273.
    • (1991) J Appl Physiol , vol.70 , pp. 267-273
    • Wong, L.B.1    Miller, I.F.2    Yeates, D.B.3
  • 47
    • 0027339305 scopus 로고
    • NK1 receptors mediate the increase in mucociliary activity produced by tachykinins
    • Lindberg S, Dolata J. NK1 receptors mediate the increase in mucociliary activity produced by tachykinins. Eur J Pharmacol 1993;231:375-380.
    • (1993) Eur J Pharmacol , vol.231 , pp. 375-380
    • Lindberg, S.1    Dolata, J.2
  • 48
    • 0002784280 scopus 로고    scopus 로고
    • Neurogenic inflammation: Reevaluation of axon reflex theory
    • Geppetti P. Holzer P, editors. New York: CRC Press
    • Szolcsanyi J. Neurogenic inflammation: Reevaluation of axon reflex theory. In: Geppetti P. Holzer P, editors. Neurogenic inflammation. New York: CRC Press; 1996. p. 33-42.
    • (1996) Neurogenic inflammation , pp. 33-42
    • Szolcsanyi, J.1
  • 50
    • 0035891725 scopus 로고    scopus 로고
    • Angiogenesis and remodeling of airway vasculature in chronic inflammation
    • McDonald DM. Angiogenesis and remodeling of airway vasculature in chronic inflammation. Am J Respir Crit Care Med 2001:164(10 Suppl S):S39-S45.
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.10 SUPPL. S
    • McDonald, D.M.1
  • 53
    • 0036569771 scopus 로고    scopus 로고
    • Assessment of microvascular leakage via sputum induction: The role of substance P and neurokinin A in patients with asthma
    • Van Rensen ELJ, Hiemstra PS, Rabe KF, Sterk PJ. Assessment of microvascular leakage via sputum induction: The role of substance P and neurokinin A in patients with asthma. Am J Respir Crit Care Med 2002;165:1275-1279.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1275-1279
    • Van Rensen, E.L.J.1    Hiemstra, P.S.2    Rabe, K.F.3    Sterk, P.J.4
  • 54
    • 0030094526 scopus 로고    scopus 로고
    • Substance P (NK1) receptor immunoreactivity on endothelial cells of the rat tracheal mucosa
    • Bowden JJ, Baluk P, Lefevre PM, Vigna SR, McDonald DM. Substance P (NK1) receptor immunoreactivity on endothelial cells of the rat tracheal mucosa. Am J Physiol 1996;270:L404-L414.
    • (1996) Am J Physiol , vol.270
    • Bowden, J.J.1    Baluk, P.2    Lefevre, P.M.3    Vigna, S.R.4    McDonald, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.