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Volumn 280, Issue 1 24-1, 2001, Pages

IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils

Author keywords

Airway epithelium; Epidermal growth factor receptor activation; Interleukin; Mucus hypersecretion; T helper 2 cytokine

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 13; MUCIN;

EID: 0035009330     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.1.l134     Document Type: Article
Times cited : (235)

References (33)
  • 1
    • 0026503978 scopus 로고
    • Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack
    • Aikawa T, Shimura S, Sasaki H, Ebina M, and Takishima T. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest 101: 916-921, 1992.
    • (1992) Chest , vol.101 , pp. 916-921
    • Aikawa, T.1    Shimura, S.2    Sasaki, H.3    Ebina, M.4    Takishima, T.5
  • 2
    • 0031808337 scopus 로고    scopus 로고
    • Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway
    • Amishima M, Munakata M, Nasuhara Y, Sato A, Takahashi T, Homma Y, and Kawakami Y. Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway. Am J Respir Crit Care Med 157: 1907-1912, 1998.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1907-1912
    • Amishima, M.1    Munakata, M.2    Nasuhara, Y.3    Sato, A.4    Takahashi, T.5    Homma, Y.6    Kawakami, Y.7
  • 6
    • 0032442862 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13: Their similarities and discrepancies
    • Chomarat P and Banchereau J. Interleukin-4 and interleukin-13: their similarities and discrepancies. Int Rev Immunol 17: 1-52, 1998.
    • (1998) Int Rev Immunol , vol.17 , pp. 1-52
    • Chomarat, P.1    Banchereau, J.2
  • 7
    • 0033562979 scopus 로고    scopus 로고
    • Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils
    • Cohn L, Homer R, MacLeod H, Mohrs M, Brombacher F, and Bottomly K. Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils. J Immunol 162: 6178-6183, 1999.
    • (1999) J Immunol , vol.162 , pp. 6178-6183
    • Cohn, L.1    Homer, R.2    MacLeod, H.3    Mohrs, M.4    Brombacher, F.5    Bottomly, K.6
  • 8
    • 0030689729 scopus 로고    scopus 로고
    • Induction of airway mucus production by T helper 2 (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production
    • Cohn L, Homer RJ, Marinov A, Rankin J, and Bottomly K. Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 186: 1737-1747, 1997.
    • (1997) J Exp Med , vol.186 , pp. 1737-1747
    • Cohn, L.1    Homer, R.J.2    Marinov, A.3    Rankin, J.4    Bottomly, K.5
  • 10
    • 0033563258 scopus 로고    scopus 로고
    • IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo
    • Dabbagh K, Takeyama K, Lee HM, Ueki IF, Lausier JA, and Nadel JA. IL-4 induces mucin gene expression and goblet cell metaplasia in vitro and in vivo. J Immunol 162: 6233-6237, 1999.
    • (1999) J Immunol , vol.162 , pp. 6233-6237
    • Dabbagh, K.1    Takeyama, K.2    Lee, H.M.3    Ueki, I.F.4    Lausier, J.A.5    Nadel, J.A.6
  • 11
    • 0030866050 scopus 로고    scopus 로고
    • Endogenous PMN-derived reactive oxygen intermediates provide feedback regulation on respiratory burst signal transduction
    • Derevianko A, D'Amico R, Graeber T, Keeping H, and Simms HH. Endogenous PMN-derived reactive oxygen intermediates provide feedback regulation on respiratory burst signal transduction. J Leukoc Biol 62: 268-276, 1997.
    • (1997) J Leukoc Biol , vol.62 , pp. 268-276
    • Derevianko, A.1    D'Amico, R.2    Graeber, T.3    Keeping, H.4    Simms, H.H.5
  • 17
    • 0019413616 scopus 로고
    • Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells
    • Hunter T and Cooper JA. Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell 24: 741-752, 1981.
    • (1981) Cell , vol.24 , pp. 741-752
    • Hunter, T.1    Cooper, J.A.2
  • 18
    • 0014621097 scopus 로고
    • Cell-degeneration pattern in bone marrow and blood of guinea pigs following administration of cyclophosphamide
    • Kaul M and Hudson G. Cell-degeneration pattern in bone marrow and blood of guinea pigs following administration of cyclophosphamide. Acta Haematol 42: 42-49, 1969.
    • (1969) Acta Haematol , vol.42 , pp. 42-49
    • Kaul, M.1    Hudson, G.2
  • 19
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • Kuperman D, Schofield B, Wills-Karp M, and Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 187: 939-948, 1998.
    • (1998) J Exp Med , vol.187 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills-Karp, M.3    Grusby, M.J.4
  • 22
    • 0026933007 scopus 로고
    • Human lung mast cells and pulmonary macrophages produce tumor necrosis factor-alpha in sensitized lung tissue after IgE receptor triggering
    • Ohkawara Y, Yamauchi K, Tanno Y, Tamura G, Ohtani H, Nagura H, Ohkuda K, and Takishima T. Human lung mast cells and pulmonary macrophages produce tumor necrosis factor-alpha in sensitized lung tissue after IgE receptor triggering. Am J Respir Cell Mol Biol 7: 385-392, 1992.
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 385-392
    • Ohkawara, Y.1    Yamauchi, K.2    Tanno, Y.3    Tamura, G.4    Ohtani, H.5    Nagura, H.6    Ohkuda, K.7    Takishima, T.8
  • 23
    • 16044371529 scopus 로고    scopus 로고
    • Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
    • Rankin JA, Picarella DE, Geba GP, Temann UA, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, and Flavell RA. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 93: 7821-7825, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7821-7825
    • Rankin, J.A.1    Picarella, D.E.2    Geba, G.P.3    Temann, U.A.4    Prasad, B.5    DiCosmo, B.6    Tarallo, A.7    Stripp, B.8    Whitsett, J.9    Flavell, R.A.10
  • 25
    • 0026026853 scopus 로고
    • Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma
    • Saetta MA, Di Stefano A, Rosino C, Thiene G, and Fabbri LM. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am J Respir Dis 143: 138-143, 1991.
    • (1991) Am J Respir Dis , vol.143 , pp. 138-143
    • Saetta, M.A.1    Di Stefano, A.2    Rosino, C.3    Thiene, G.4    Fabbri, L.M.5
  • 26
    • 0027393655 scopus 로고
    • Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells
    • Schmiegel W, Roeder C, Schmielau J, Rodeck U, and Kalthoff H. Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells. Proc Natl Acad Sci USA 90: 863-867, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 863-867
    • Schmiegel, W.1    Roeder, C.2    Schmielau, J.3    Rodeck, U.4    Kalthoff, H.5
  • 27
    • 0034141938 scopus 로고    scopus 로고
    • Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: Role of neutrophils
    • Takeyama K, Dabbagh K, Shim JJ, Dao-Pick T, Ueki IF, and Nadel JA. Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils. J Immunol 164: 1546-1552, 2000.
    • (2000) J Immunol , vol.164 , pp. 1546-1552
    • Takeyama, K.1    Dabbagh, K.2    Shim, J.J.3    Dao-Pick, T.4    Ueki, I.F.5    Nadel, J.A.6
  • 31
    • 0024602827 scopus 로고
    • Tissue destruction by neutrophils
    • Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 320: 365-376, 1989.
    • (1989) N Engl J Med , vol.320 , pp. 365-376
    • Weiss, S.J.1
  • 33
    • 0027815143 scopus 로고
    • Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue
    • Xing Z, Kirpalani H, Torry D, Jordana M, and Gauldie J. Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue. Am J Pathol 143: 1009-1015, 1993.
    • (1993) Am J Pathol , vol.143 , pp. 1009-1015
    • Xing, Z.1    Kirpalani, H.2    Torry, D.3    Jordana, M.4    Gauldie, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.