Airway epithelial repair: Breathtakingly quick and multipotentially pathogenic

Thorax

Volumn 52, Issue 11, 1997, Pages 1010-1012

  Erjefalt J S ^a,b,c   Persson, C G A ^a,b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

Asthma pathology; Epithelial repair; Mucosal barrier

Indexed keywords

ARTICLE; ASTHMA; CELL PROTECTION; DESQUAMATION; EPITHELIUM CELL; HUMAN; PATHOLOGY; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; TISSUE REPAIR;

EID: 0030778321     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.52.11.1010     Document Type: Article

References (12)

1. Persson CGA. Centennial notions of asthma as a desquamative, eosinophilic, exudative, and steroid-sensitive disease. Lancet 1997 (in press).
2. Caroll N, Elliot J, Morton A, James A. The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 1993;147:405-10.
3. Söderberg M, Hellström S, Sandström T, Lundgren R, Bergh A. Structural characterization of bronchial mucosal biopsies from healthy volunteers: a light and electron microscopical study. Eur Respir J 1990;3:261-6.
4. Jeffery PK, Wardlaw AJ, Nelson FC, Collins JV, Kay AB. Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 1989;40:1745-53.
5. Erjefält JS, Korsgren M, Nilsson MC, Sundler F, Persson CGA. Prompt epithelial damage and restitution processes in allergen challenged guinea-pig trachea. Clin Exp Allergy 1997;27 (in press).
6. Persson CGA, Andersson M, Greiff L, Svensson C, Erjefält JS, Sundler F, et al. Airway permeability. Clin Exp Allergy 1995;23:807-14.
7. Erjefält JS, Sundler F, Persson CGA. Airway basal cells may promptly assume a barrier structure. Thorax 1997;52: 213-7.
8. Wilhelm DL. Regeneration of tracheal epithelium. J Pathol Bacteriol 1953;LXV:543-50.
9. Erjefält JS, Erjefält I, Sundler F, Persson CGA. In vivo restitution of the airway epithelium. Cell Tissue Res 1995; 281:305-16.
10. Persson CGA, Erjefält JS, Erjefält I, Korsgren M, Nilsson M, Sundler F. Epithelial shedding-restitution as a causative process in airway inflammation. Clin Exp Allergy 1996;26: 746-55.
11. Erjefält JS, Sundler F, Persson CGA. Eosinophils, neutrophils, and venular gaps in the airway mucosa at epithelial removal restitution. Am J Respir Crit Care Med 1996;153: 1666-74.
12. Persson CGA, Erjefält JS. Ultimate activation of eosinophils in vivo: lysis and release of clusters of free eosinophil granules (Cfegs). Thorax 1997;52:569-73.