-
1
-
-
0038781698
-
Stroke: Molecular mechanisms and potential targets for treatment
-
Zheng, Z., Lee, J.E. and Yenari, M.A. Stroke: Molecular mechanisms and potential targets for treatment. Curr Mol Med 2003, 3: 361-72.
-
(2003)
Curr Mol Med
, vol.3
, pp. 361-372
-
-
Zheng, Z.1
Lee, J.E.2
Yenari, M.A.3
-
2
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone, F.C. and Feuerstein, G. Z. Inflammatory mediators and stroke: New opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999, 19: 819-34.
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
3
-
-
0035143182
-
Cerebral ischemia and inflammation
-
Iadecola, C. and Alexander, M. Cerebral ischemia and inflammation. Curr Opin Neurol 2001, 14: 89-94.
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 89-94
-
-
Iadecola, C.1
Alexander, M.2
-
4
-
-
0035122040
-
Programmed cell death in cerebral ischemia
-
Graham, S.H. and Chen, J. Programmed cell death in cerebral ischemia. J Cereb Blood Flow Metab 2001, 21: 99-109.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 99-109
-
-
Graham, S.H.1
Chen, J.2
-
5
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M.O. The biochemistry of apoptosis. Nature 2000, 407: 770-6.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
6
-
-
0029079440
-
Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion
-
Linnik, M.D., Miller, J.A., Sprinkle-Cavallo, J. et al. Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion. Brain Res Mol Brain Res 1995, 32: 116-24.
-
(1995)
Brain Res Mol Brain Res
, vol.32
, pp. 116-124
-
-
Linnik, M.D.1
Miller, J.A.2
Sprinkle-Cavallo, J.3
-
7
-
-
0032525260
-
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia
-
Namura, S., Zhu, J., Fink, K. et al. Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia. J Neurosci 1998, 18: 3659-68.
-
(1998)
J Neurosci
, vol.18
, pp. 3659-3668
-
-
Namura, S.1
Zhu, J.2
Fink, K.3
-
8
-
-
0032054867
-
Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat
-
Li, Y., Powers, C., Jiang, N. and Chopp, M. Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat. J Neurol Sci 1998, 156: 119-32.
-
(1998)
J Neurol Sci
, vol.156
, pp. 119-132
-
-
Li, Y.1
Powers, C.2
Jiang, N.3
Chopp, M.4
-
9
-
-
0029001888
-
Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats
-
discussion 1257-8
-
Li, Y., Chopp, M., Jiang, N., Zhang, Z.G. and Zaloga, C. Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats. Stroke 1995, 26: 1252-7; discussion 1257-8.
-
(1995)
Stroke
, vol.26
, pp. 1252-1257
-
-
Li, Y.1
Chopp, M.2
Jiang, N.3
Zhang, Z.G.4
Zaloga, C.5
-
10
-
-
0030053303
-
Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis
-
Charriaut-Marlangue, C., Margaill, I., Represa, A., Popovici, T., Plotkine, M. and Ben-Ari, Y. Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis. J Cereb Blood Flow Metab 1996, 16: 186-94.
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 186-194
-
-
Charriaut-Marlangue, C.1
Margaill, I.2
Represa, A.3
Popovici, T.4
Plotkine, M.5
Ben-Ari, Y.6
-
11
-
-
0037383230
-
Apoptosis occurs in the penumbra zone during short-duration focal ischemia in the rat
-
Kametsu, Y., Osuga, S. and Hakim, A.M. Apoptosis occurs in the penumbra zone during short-duration focal ischemia in the rat. J Cereb Blood Flow Metab 2003, 23: 416-22.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 416-422
-
-
Kametsu, Y.1
Osuga, S.2
Hakim, A.M.3
-
12
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
Mattson, M.P. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000, 1: 120-9.
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, pp. 120-129
-
-
Mattson, M.P.1
-
13
-
-
0035676977
-
The machinery of programmed cell death
-
Zimmermann, K.C., Bonzon, C. and Green, D.R. The machinery of programmed cell death. Pharmacol Ther 2001, 92: 57-70.
-
(2001)
Pharmacol Ther
, vol.92
, pp. 57-70
-
-
Zimmermann, K.C.1
Bonzon, C.2
Green, D.R.3
-
14
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri, K.F. and Kroemer, G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 2001, 3: E255-63.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
15
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D.R: and Reed, J.C. Mitochondria and apoptosis. Science 1998, 281: 1309-12.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
16
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li, H., Zhu, H., Xu, C.J. and Yuan, J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998, 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
17
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo, I., Oliver, H., Lutter, M., Luo, X. and Wang, X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999, 15: 269-90.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
18
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi, A. and Dixit, V.M. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 1999, 11: 255-60.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
19
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi, A. and Dixit, V.M. Death receptors: Signaling and modulation. Science 1998, 281: 1305-8.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
20
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo, X., Budihardjo, I., Zou, H., Slaughter, C. and Wang, X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998, 94:481-90.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
21
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
Kroenier, G., Dallaporta, B. and Resche-Rigon, M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998, 60: 619-42.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 619-642
-
-
Kroenier, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
22
-
-
0037318902
-
Mitochondria, AIF and caspases - Rivaling for cell death execution
-
Penninger, J.M. and Kroemer, G. Mitochondria, AIF and caspases - Rivaling for cell death execution. Nat Cell Biol 2003, 5: 97-9.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 97-99
-
-
Penninger, J.M.1
Kroemer, G.2
-
23
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S.A., Lorenzo, H.K., Zamzami, N. et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999, 397: 441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
24
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas, E., Susin, S.A., Zamzami, N. et al. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000, 14:729-39.
-
(2000)
FASEB J
, vol.14
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
-
25
-
-
0033010612
-
Apoptosis inducing factor (AIF): A phylogenetically old, caspase-independent effector of cell death
-
Lorenzo, H.K., Susin, S.A., Penninger, J. and Kroemer, G. Apoptosis inducing factor (AIF): A phylogenetically old, caspase-independent effector of cell death. Cell Death Differ 1999, 6: 516-24.
-
(1999)
Cell Death Differ
, vol.6
, pp. 516-524
-
-
Lorenzo, H.K.1
Susin, S.A.2
Penninger, J.3
Kroemer, G.4
-
26
-
-
0033579810
-
Mitochondrial release of caspase-2 and -9 during the apoptotic process
-
Susin, S.A., Lorenzo, H.K., Zamzami, N. et al. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J Exp Med 1999, 189: 381-94.
-
(1999)
J Exp Med
, vol.189
, pp. 381-394
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
27
-
-
0032461935
-
Apoptotic signal transduction: Emerging pathways
-
Wilson, M.R. Apoptotic signal transduction: Emerging pathways. Biochem Cell Biol 1998, 76: 573-82.
-
(1998)
Biochem Cell Biol
, vol.76
, pp. 573-582
-
-
Wilson, M.R.1
-
28
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
Wang, X., Yang, C., Chal, J., Shi, Y. and Xue, D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 2002, 298: 1587-92.
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chal, J.3
Shi, Y.4
Xue, D.5
-
29
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu, X., Kim, C.N., Yang, J., Jemmerson, R. and Wang, X. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996, 86: 147-57.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
30
-
-
0033612939
-
Post-treatment with the immunosuppressant cyclosporin A in transient focal ischemia
-
Yoshimoto, T. and Siesjo, B.K. Post-treatment with the immunosuppressant cyclosporin A in transient focal ischemia. Brain Res 1999, 839: 283-91.
-
(1999)
Brain Res
, vol.839
, pp. 283-291
-
-
Yoshimoto, T.1
Siesjo, B.K.2
-
31
-
-
0033495895
-
Blockade of the mitochondrial permeability transition pore diminishes Infarct size in the rat after transient middle cerebral artery occlusion
-
Matsumoto, S., Friberg, H., Ferrand-Drake, M. and Wieloch, T. Blockade of the mitochondrial permeability transition pore diminishes Infarct size in the rat after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 1999, 19: 736-41.
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, pp. 736-741
-
-
Matsumoto, S.1
Friberg, H.2
Ferrand-Drake, M.3
Wieloch, T.4
-
32
-
-
0034069630
-
Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats
-
Sasaki, C., Kitagawa, H., Zhang, W.R., Warita, H., Sakai, K. and Abe, K. Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats. Neurol Res 2000, 22: 223-8.
-
(2000)
Neurol Res
, vol.22
, pp. 223-228
-
-
Sasaki, C.1
Kitagawa, H.2
Zhang, W.R.3
Warita, H.4
Sakai, K.5
Abe, K.6
-
33
-
-
0034655765
-
The cytosolic antiaxidant cop. per/zinc-Superaxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice
-
Fujimura, M., Morita-Fujimura, Y., Noshita, N., Sugawara, T., Kawase, M. and Chan, P.H. The cytosolic antiaxidant cop. per/zinc-Superaxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice. J Neurosci 2000, 20:2817-24.
-
(2000)
J Neurosci
, vol.20
, pp. 2817-2824
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Noshita, N.3
Sugawara, T.4
Kawase, M.5
Chan, P.H.6
-
34
-
-
0033570503
-
Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia
-
Sugawara, T., Fujimura, M., Morita-Fujimura, Y., Kawase, M. and Chan, P.H. Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. J Neurosci 1999, 19: RC39.
-
(1999)
J Neurosci
, vol.19
-
-
Sugawara, T.1
Fujimura, M.2
Morita-Fujimura, Y.3
Kawase, M.4
Chan, P.H.5
-
35
-
-
0033135367
-
Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DIVA fragmentation after permanent focal cerebral ischemia in mice
-
Fujimura, M., Morita-Fujimura, Y., Kawase, M. et al. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DIVA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci 1999, 19: 3414-22.
-
(1999)
J Neurosci
, vol.19
, pp. 3414-3422
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Kawase, M.3
-
36
-
-
0032884746
-
Translocation of cytochrome c following transient global ischemia in the gerbil
-
Antonawich, F.J. Translocation of cytochrome c following transient global ischemia in the gerbil. Neurosci Lett 1999, 274: 123-6.
-
(1999)
Neurosci Lett
, vol.274
, pp. 123-126
-
-
Antonawich, F.J.1
-
37
-
-
0031737635
-
Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats
-
Fujimura, M., Morita-Fujimura, Y., Murakami, K., Kawase, M. and Chan, P.H. Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab 1998, 18: 1239-47.
-
(1998)
J Cereb Blood Flow Metab
, vol.18
, pp. 1239-1247
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Murakami, K.3
Kawase, M.4
Chan, P.H.5
-
38
-
-
0036137197
-
Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke
-
Yenari, M.A., Iwayama, S., Cheng, D. et al. Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke. J Cereb Blood Flow Metab 2002, 22: 29-38.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 29-38
-
-
Yenari, M.A.1
Iwayama, S.2
Cheng, D.3
-
39
-
-
0037191413
-
Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion
-
Shibata, M., Hattori, H., Sasaki, T., Gotch, J., Hamada, J. and Fukuuchi, Y. Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion. Neuroreport 2002, 13: 1985-8.
-
(2002)
Neuroreport
, vol.13
, pp. 1985-1988
-
-
Shibata, M.1
Hattori, H.2
Sasaki, T.3
Gotch, J.4
Hamada, J.5
Fukuuchi, Y.6
-
40
-
-
0037213368
-
The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
-
Borner, C. The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions. Mol Immunol 2003, 39: 615-47.
-
(2003)
Mol Immunol
, vol.39
, pp. 615-647
-
-
Borner, C.1
-
41
-
-
0032575688
-
The Bcl-2 protein family. Arbiters of cell survival
-
Adams, J.M. and Cory, S. The Bcl-2 protein family. Arbiters of cell survival. Science 1998, 281: 1322-6.
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
42
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D.R. and Reed, J.C. Mitochondria and apoptosis. Science 1998, 281: 1309-12.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
43
-
-
0033971901
-
Bcl-2 family: Life-or-death switch
-
Tsujimoto, Y. and Shimizu, S. Bcl-2 family: Life-or-death switch. FEBS Lett 2000, 466: 6-10.
-
(2000)
FEBS Lett
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
44
-
-
0036187675
-
Function of BID - A molecule of the bcl-2 family - In ischemic cell death in the brain
-
Plesnila, N., Zinkel, S., Amin-Hanjani, S., Qiu, J., Korsmeyer, S.J. and Moskowitz, M.A. Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain. Eur Surg Res 2002, 34: 37-41.
-
(2002)
Eur Surg Res
, vol.34
, pp. 37-41
-
-
Plesnila, N.1
Zinkel, S.2
Amin-Hanjani, S.3
Qiu, J.4
Korsmeyer, S.J.5
Moskowitz, M.A.6
-
45
-
-
0035910099
-
BID mediates neuronal cell death after oxygen/glucose deprivation and focal cerebral ischemia
-
Plesnila, N., Zinkel, S., Le, D.A. et al. BID mediates neuronal cell death after oxygen/glucose deprivation and focal cerebral ischemia. Proc Natl. Acad Sci USA 2001, 98:15318-23.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15318-15323
-
-
Plesnila, N.1
Zinkel, S.2
Le, D.A.3
-
46
-
-
0036830353
-
Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia
-
Yin, X.M., Luo, Y., Cao, G. et al. Bid-mediated mitochondrial pathway is critical to ischemic neuronal apoptosis and focal cerebral ischemia. J Biol Chem 2002, 277: 42074-81.
-
(2002)
J Biol Chem
, vol.277
, pp. 42074-42081
-
-
Yin, X.M.1
Luo, Y.2
Cao, G.3
-
47
-
-
0036301277
-
Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice
-
Shibata, M., Hattori, H., Sasaki, T., Gotoh, J., Hamada, J. and Fukuuchi, Y. Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab 2002, 22: 810-20.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 810-820
-
-
Shibata, M.1
Hattori, H.2
Sasaki, T.3
Gotoh, J.4
Hamada, J.5
Fukuuchi, Y.6
-
48
-
-
0035045290
-
Intracellular Bax translocatlon after transient cerebral ischemia: Implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death
-
Cao, G., Minami, M., Pei, W. et al. Intracellular Bax translocatlon after transient cerebral ischemia: Implications for a role of the mitochondrial apoptotic signaling pathway in ischemic neuronal death. J Cereb Blood Flow Metab 2001, 21: 321-33.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 321-333
-
-
Cao, G.1
Minami, M.2
Pei, W.3
-
49
-
-
0031032232
-
Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia
-
Chen, J., Graham S.H., Nakayama, M. et al. Apoptosis repressor genes Bcl-2 and Bcl-x-long are expressed in the rat brain following global ischemia. J Cereb Blood Flow Metab 1997, 17: 2-10.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 2-10
-
-
Chen, J.1
Graham, S.H.2
Nakayama, M.3
-
50
-
-
0000064578
-
Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats
-
Gillardon, F., Lenz, C., Waschke, K.F. et al. Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Brain Res Mol Brain Res 1996, 40: 254-60.
-
(1996)
Brain Res Mol Brain Res
, vol.40
, pp. 254-260
-
-
Gillardon, F.1
Lenz, C.2
Waschke, K.F.3
-
51
-
-
0035426040
-
Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in Chinese hamster ovary cells
-
Slikker, W., III, Desai, V.G., Duhart, H., Feuers, R. and Imam, S.Z. Hypothermia enhances bcl-2 expression and protects against oxidative stress-induced cell death in Chinese hamster ovary cells. Free Radic Biol Med 2001, 31: 405-11.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 405-411
-
-
Slikker III, W.1
Desai, V.G.2
Duhart, H.3
Feuers, R.4
Imam, S.Z.5
-
52
-
-
0034703589
-
Immunohistochemical expression of Bcl-2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat
-
Prakasa Babu, P., Yoshida, Y., Su, M., Segura, M., Kawamura, S. and Yasui, N. Immunohistochemical expression of Bcl-2, Bax and cytochrome c following focal cerebral ischemia and effect of hypothermia in rat. Neurosci Lett 2000, 291: 196-200.
-
(2000)
Neurosci Lett
, vol.291
, pp. 196-200
-
-
Prakasa Babu, P.1
Yoshida, Y.2
Su, M.3
Segura, M.4
Kawamura, S.5
Yasui, N.6
-
53
-
-
0035500995
-
Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia
-
Zhang, Z., Sobel, R.A., Cheng, D., Steinberg, G.K. and Yenari, M.A. Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia. Brain Res Mol Brain Res 2001, 95: 75-85.
-
(2001)
Brain Res Mol Brain Res
, vol.95
, pp. 75-85
-
-
Zhang, Z.1
Sobel, R.A.2
Cheng, D.3
Steinberg, G.K.4
Yenari, M.A.5
-
54
-
-
0036139651
-
Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade
-
Xu, L., Yenari, M.A., Steinberg, G.K. and Giffard, R.G. Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade. J Cereb Blood Flow Metab 2002, 22: 21-8.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 21-28
-
-
Xu, L.1
Yenari, M.A.2
Steinberg, G.K.3
Giffard, R.G.4
-
55
-
-
0032716224
-
Overexpression of bcl-2, bcl-XL or hsp 70 in murine cortical astrocytes reduces injury of co-cultured neurons
-
Xu, L., Lee, J.E. and Giffard, R.G. Overexpression of bcl-2, bcl-XL or hsp 70 in murine cortical astrocytes reduces injury of co-cultured neurons. Neurosci Lett 1999, 277: 193-7.
-
(1999)
Neurosci Lett
, vol.277
, pp. 193-197
-
-
Xu, L.1
Lee, J.E.2
Giffard, R.G.3
-
56
-
-
0036846120
-
Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: Interactions with pathways of oxidative damage
-
Howard, S., Bottino, C., Brooke, S., Cheng, E., Giffard, R.G. and Sapolsky, R. Neuroprotective effects of bcl-2 overexpression in hippocampal cultures: Interactions with pathways of oxidative damage. J Neurochem 2002, 83: 914-23.
-
(2002)
J Neurochem
, vol.83
, pp. 914-923
-
-
Howard, S.1
Bottino, C.2
Brooke, S.3
Cheng, E.4
Giffard, R.G.5
Sapolsky, R.6
-
57
-
-
0038587580
-
Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity
-
Zhao, H., Yenari, M.A., Cheng, D., Sapolsky, R.M. and Steinberg, G.K. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem 2003, 85: 1026-36.
-
(2003)
J Neurochem
, vol.85
, pp. 1026-1036
-
-
Zhao, H.1
Yenari, M.A.2
Cheng, D.3
Sapolsky, R.M.4
Steinberg, G.K.5
-
58
-
-
0030025668
-
Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
-
Lawrence, M.S., Ho, D.Y., Sun, G.H., Steinberg, G.K. and Sapolsky, R.M. Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. J Neurosci 1996, 16: 486-96.
-
(1996)
J Neurosci
, vol.16
, pp. 486-496
-
-
Lawrence, M.S.1
Ho, D.Y.2
Sun, G.H.3
Steinberg, G.K.4
Sapolsky, R.M.5
-
59
-
-
0030772541
-
Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke
-
Lawrence, M.S., McLaughlin, J.R., Sun, G..H. et al. Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke. J Cereb Blood Flow Metab 1997, 17:: 740-4.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 740-744
-
-
Lawrence, M.S.1
McLaughlin, J.R.2
Sun, G.H.3
-
60
-
-
0030461002
-
A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult
-
Jia, W.W., Wang, Y., Qiang, D., Tufaro, F., Remington, R. and Cynader, M. A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult. Brain Res Mol Brain Res 1996, 42: 350-3.
-
(1996)
Brain Res Mol Brain Res
, vol.42
, pp. 350-353
-
-
Jia, W.W.1
Wang, Y.2
Qiang, D.3
Tufaro, F.4
Remington, R.5
Cynader, M.6
-
61
-
-
0028981908
-
Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia
-
discussion 1675
-
Linnik, M.D., Zahos, P., Geschwind, M.D. and Federoff, HJ. Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke 1995, 26: 1670-4; discussion 1675.
-
(1995)
Stroke
, vol.26
, pp. 1670-1674
-
-
Linnik, M.D.1
Zahos, P.2
Geschwind, M.D.3
Federoff, H.J.4
-
62
-
-
0027944004
-
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
-
Martinou, J.C., Dubois-Dauphin, M., Staple, J.K. et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994, 13: 1017-30.
-
(1994)
Neuron
, vol.13
, pp. 1017-1030
-
-
Martinou, J.C.1
Dubois-Dauphin, M.2
Staple, J.K.3
-
63
-
-
0037101887
-
Effect of Bcl-x(L) overexpression on reactive oxygen species, intracellular calcium, and mitochondrial membrane potential following injury in astrocytes
-
Ouyang, Y.B., Carriedo, S.G. and Giffard, R.G. Effect of Bcl-x(L) overexpression on reactive oxygen species, intracellular calcium, and mitochondrial membrane potential following injury in astrocytes. Free Radic Biol Med 2002, 33: 544-51.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 544-551
-
-
Ouyang, Y.B.1
Carriedo, S.G.2
Giffard, R.G.3
-
64
-
-
0032589418
-
Overexpression of bcl-xL protects astrocytes from glucose deprivation and is associated with higher glutathione, ferritin, and iron levels
-
Xu, L., Koumenis, I.L., Tilly, J.L. and Giffard, R.G. Overexpression of bcl-xL protects astrocytes from glucose deprivation and is associated with higher glutathione, ferritin, and iron levels. Anesthesiology 1999, 91: 1036-46.
-
(1999)
Anesthesiology
, vol.91
, pp. 1036-1046
-
-
Xu, L.1
Koumenis, I.L.2
Tilly, J.L.3
Giffard, R.G.4
-
65
-
-
0037332406
-
Bcl-XL maintains mitochondrial function in murine astrocytes deprived of glucose
-
Ouyang, Y.B. and Giffard, R.G. Bcl-XL maintains mitochondrial function in murine astrocytes deprived of glucose. J Cereb Blood Flow Metab 2003, 23: 2759.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 2759
-
-
Ouyang, Y.B.1
Giffard, R.G.2
-
66
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer, P.H. CD95's deadly mission in the immune system. Nature 2000, 407: 789-95.
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
67
-
-
0033491193
-
CD95(APO-1/Fas)-mediated apoptosis: Live and let die
-
Krammer, P.H. CD95(APO-1/Fas)-mediated apoptosis: Live and let die. Adv Immunol 1999, 71: 163-210.
-
(1999)
Adv Immunol
, vol.71
, pp. 163-210
-
-
Krammer, P.H.1
-
68
-
-
0033562658
-
CD95 ligand (Fas-L/APO-IL) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons
-
Martin-Villalba, A., Herr, I., Jeremias, I. et al. CD95 ligand (Fas-L/APO-IL) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons. J Neurosci 1999, 19: 3809-17.
-
(1999)
J Neurosci
, vol.19
, pp. 3809-3817
-
-
Martin-Villalba, A.1
Herr, I.2
Jeremias, I.3
-
69
-
-
0035209472
-
Fas (CD95) may mediate delayed cell death in hippocampal CA1 sector after global cerebral ischemia
-
Jin, K., Graham, S.H., Mao, X., Nagayama, T., Simon, R.P. and Greenberg, D.A. Fas (CD95) may mediate delayed cell death in hippocampal CA1 sector after global cerebral ischemia. J Cereb Blood Flow Metab 2001, 21: 1411-21.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 1411-1421
-
-
Jin, K.1
Graham, S.H.2
Mao, X.3
Nagayama, T.4
Simon, R.P.5
Greenberg, D.A.6
-
70
-
-
0034666684
-
Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia
-
Rosenbaum, D.M., Gupta, G., D'Amore, J. et al. Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia. J Neurosci Res 2000, 61: 686-92.
-
(2000)
J Neurosci Res
, vol.61
, pp. 686-692
-
-
Rosenbaum, D.M.1
Gupta, G.2
D'Amore, J.3
-
71
-
-
0034915133
-
Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke
-
Martin-Villalba, A., Hahne, M., Kleber, S. et al. Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke. Cell Death Differ 2001, 8: 679-86.
-
(2001)
Cell Death Differ
, vol.8
, pp. 679-686
-
-
Martin-Villalba, A.1
Hahne, M.2
Kleber, S.3
-
72
-
-
0034495184
-
Mild hypothermia mitigates post-ischemic neuronal death following focal cerebral ischemia in rat brain: Immunohistochemical study of Fas, caspase-3 and TUNEL
-
Phanithi, P.B., Yoshida, Y., Santana, A., Su, M., Kawamura, S. and Yasui, N. Mild hypothermia mitigates post-ischemic neuronal death following focal cerebral ischemia in rat brain: Immunohistochemical study of Fas, caspase-3 and TUNEL. Neuropathology 2000, 20: 273-82.
-
(2000)
Neuropathology
, vol.20
, pp. 273-282
-
-
Phanithi, P.B.1
Yoshida, Y.2
Santana, A.3
Su, M.4
Kawamura, S.5
Yasui, N.6
-
73
-
-
0032777272
-
Caspase knockouts: Matters of life and death
-
Zheng, T.S., Hunot, S., Kuida, K. and Flavell, R.A. Caspase knockouts: Matters of life and death. Cell Death Differ 1999, 6: 1043-53.
-
(1999)
Cell Death Differ
, vol.6
, pp. 1043-1053
-
-
Zheng, T.S.1
Hunot, S.2
Kuida, K.3
Flavell, R.A.4
-
74
-
-
0344142396
-
Emerging roles of caspase-3 in apoptosis
-
Porter, A.G. and Janicke, R.U. Emerging roles of caspase-3 in apoptosis. Cell Death Differ 1999, 6: 99-104.
-
(1999)
Cell Death Differ
, vol.6
, pp. 99-104
-
-
Porter, A.G.1
Janicke, R.U.2
-
75
-
-
0032785021
-
Caspase structure, proteolytic substrates, and function during apoptotic cell death
-
Nicholson, D.W. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ 1999, 6: 1028-42.
-
(1999)
Cell Death Differ
, vol.6
, pp. 1028-1042
-
-
Nicholson, D.W.1
-
76
-
-
0032124903
-
Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
-
Chen, J., Nagayama, T., Jin, K. et al. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J Neurosci 1998, 18: 4914-28.
-
(1998)
J Neurosci
, vol.18
, pp. 4914-4928
-
-
Chen, J.1
Nagayama, T.2
Jin, K.3
-
77
-
-
0033634830
-
Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice
-
Kim, G.W., Sugawara, T. and Chan, P.H. Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice. J Cereb Blood Flow Metab 2000, 20: 1690-701.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 1690-1701
-
-
Kim, G.W.1
Sugawara, T.2
Chan, P.H.3
-
78
-
-
0034601396
-
Activation of caspase-3 in permanent and transient brain ischaemia in man
-
Love, S., Barber, R., Srinivasan, A. and Wilcock, G.K. Activation of caspase-3 in permanent and transient brain ischaemia in man. Neuroreport 2000, 11: 2495-9.
-
(2000)
Neuroreport
, vol.11
, pp. 2495-2499
-
-
Love, S.1
Barber, R.2
Srinivasan, A.3
Wilcock, G.K.4
-
79
-
-
0032885388
-
Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
-
Earnshaw, W.C., Martins, L.M. and Kaufmann, S.H. Mammalian caspases: Structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 1999, 68: 383-424.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
80
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari, M., Quan, L.T., O'Rourke, K. et al. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995, 81: 801-9.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
-
81
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A. and Nagata, S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998, 391: 43-50.
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
82
-
-
0036523088
-
Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
-
Anantharam, V., Kitazawa, M., Wagner, J., Kaul, S. and Kanthasamy, A.G. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. J Neurosci 2002, 22: 1738-51.
-
(2002)
J Neurosci
, vol.22
, pp. 1738-1751
-
-
Anantharam, V.1
Kitazawa, M.2
Wagner, J.3
Kaul, S.4
Kanthasamy, A.G.5
-
83
-
-
0342546527
-
BDNF blocks caspase-3 activation in neonatal hypaxia-ischemia
-
Han, B.H., D'Costa, A., Back, S.A. et al. BDNF blocks caspase-3 activation in neonatal hypaxia-ischemia. Neurobiol Dis 2000, 7: 38-53.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 38-53
-
-
Han, B.H.1
D'Costa, A.2
Back, S.A.3
-
84
-
-
0036012750
-
Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia
-
Cao, G., Luo, Y., Nagayama, T. et al. Cloning and characterization of rat caspase-9: Implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia. J Cereb Blood Flow Metab 2002, 22: 534-46.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 534-546
-
-
Cao, G.1
Luo, Y.2
Nagayama, T.3
-
85
-
-
0034192466
-
Dual role of caspase-II in mediating activation of caspase-1 and caspase-3 under pathological conditions
-
Kang, S.I., Wang, S., Hara, H. et al. Dual role of caspase-II in mediating activation of caspase-1 and caspase-3 under pathological conditions. J Cell Biol 2000, 149: 613-22.
-
(2000)
J Cell Biol
, vol.149
, pp. 613-622
-
-
Kang, S.I.1
Wang, S.2
Hara, H.3
-
86
-
-
0037069451
-
Caspase activation and neuroprotection in caspase-3-deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation
-
Le, D.A., Wu, Y., Huang, Z. et al. Caspase activation and neuroprotection in caspase-3-deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation. Proc Natl Acad Sci USA 2002, 99:15188-93.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15188-15193
-
-
Le, D.A.1
Wu, Y.2
Huang, Z.3
-
87
-
-
0032918137
-
Caspases as treatment targets in stroke and neurodegenerative diseases
-
Schulz, J.B., Weller, M. and Moskowitz, M.A. Caspases as treatment targets in stroke and neurodegenerative diseases. Ann Neurol 1999, 45: 421-9.
-
(1999)
Ann Neurol
, vol.45
, pp. 421-429
-
-
Schulz, J.B.1
Weller, M.2
Moskowitz, M.A.3
-
88
-
-
0035398570
-
Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?
-
Loetscher, H., Niederhauser, O., Kemp, J. and Gill, R. Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia? Drug Discov Today 2001, 6: 671-80.
-
(2001)
Drug Discov Today
, vol.6
, pp. 671-680
-
-
Loetscher, H.1
Niederhauser, O.2
Kemp, J.3
Gill, R.4
-
89
-
-
0035012926
-
Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c from mitochondria in a rat forebrain ischemia model
-
Zhan, R.Z., Wu, C., Fujihara, H. et al. Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c from mitochondria in a rat forebrain ischemia model. J Cereb Blood Flow Metab 2001, 21: 529-40.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 529-540
-
-
Zhan, R.Z.1
Wu, C.2
Fujihara, H.3
-
90
-
-
0036208147
-
Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain
-
Gill, R., Soriano, M., Blomgren, K. et al. Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain. J Cereb Blood Flow Metab 2002, 22: 420-30.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 420-430
-
-
Gill, R.1
Soriano, M.2
Blomgren, K.3
-
91
-
-
0036431535
-
Caspase-3-dependent and -independent apoptosis in focal brain ischemia
-
Didenko, V.V., Ngo, H., Minchew, C.L., Boudreaux, D.J., Widmayer, M.A. and Baskin, D.S. Caspase-3-dependent and -independent apoptosis in focal brain ischemia. Mol Med 2002, 8: 347-52.
-
(2002)
Mol Med
, vol.8
, pp. 347-352
-
-
Didenko, V.V.1
Ngo, H.2
Minchew, C.L.3
Boudreaux, D.J.4
Widmayer, M.A.5
Baskin, D.S.6
-
92
-
-
0035890012
-
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus
-
Braun, J.S., Novak, R., Murray, PJ. et al. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J Infect Dis 2001, 184: 1300-9.
-
(2001)
J Infect Dis
, vol.184
, pp. 1300-1309
-
-
Braun, J.S.1
Novak, R.2
Murray, P.J.3
-
93
-
-
0035861677
-
Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria
-
Jiang, D., Sullivan, P.G., Sensi, S.L., Steward, O. and Weiss, J.H. Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria. J Biol Chem 2001, 276:47524-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 47524-47529
-
-
Jiang, D.1
Sullivan, P.G.2
Sensi, S.L.3
Steward, O.4
Weiss, J.H.5
-
94
-
-
0036323443
-
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
-
Cregan, S.P., Fortin, A., MacLaurin, J.G. et al. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J Cell Biol 2002, 158: 507-17.
-
(2002)
J Cell Biol
, vol.158
, pp. 507-517
-
-
Cregan, S.P.1
Fortin, A.2
MacLaurin, J.G.3
-
95
-
-
0036836070
-
Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress
-
Fonfria, E., Dare, E., Benelli, M., Sunol, C. and Ceccatelli, S. Translocation of apoptosis-inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress. Eur J Neurosci 2002, 16: 2013-6.
-
(2002)
Eur J Neurosci
, vol.16
, pp. 2013-2016
-
-
Fonfria, E.1
Dare, E.2
Benelli, M.3
Sunol, C.4
Ceccatelli, S.5
-
96
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu, S.W., Wang, H., Poiras, M.F. et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002, 297: 259-63.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poiras, M.F.3
-
97
-
-
0035069843
-
Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo
-
Hisatomi, T., Sakamoto, T., Murata, T. et al. Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. Am J Pathol 2001, 158:1271-8.
-
(2001)
Am J Pathol
, vol.158
, pp. 1271-1278
-
-
Hisatomi, T.1
Sakamoto, T.2
Murata, T.3
-
98
-
-
20244364788
-
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite
-
Zhang, X., Chen, J., Graham, S.H. et al. Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J Neurochem 2002, 82: 181-91.
-
(2002)
J Neurochem
, vol.82
, pp. 181-191
-
-
Zhang, X.1
Chen, J.2
Graham, S.H.3
-
99
-
-
0037654371
-
HSV-mediated Bcl-2 transfection blocks apoptosis inducing factor (AIF) translocation after focal ischemia in rat
-
Zhao, H., Yenari, M.A., Cheng, D., Sapolsky, R.M. and Steinberg, G.K. HSV-mediated Bcl-2 transfection blocks apoptosis inducing factor (AIF) translocation after focal ischemia in rat. Stroke 2003, 34: 241.
-
(2003)
Stroke
, vol.34
, pp. 241
-
-
Zhao, H.1
Yenari, M.A.2
Cheng, D.3
Sapolsky, R.M.4
Steinberg, G.K.5
-
100
-
-
0037384802
-
Signaling of cell death and cell survival fallowing focal cerebral ischemia: Life and death struggle in the penumbra
-
Ferrer, I. and Planas, A.M. Signaling of cell death and cell survival fallowing focal cerebral ischemia: Life and death struggle in the penumbra. J Neuropathol Exp Neurol 2003, 62: 329-39.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 329-339
-
-
Ferrer, I.1
Planas, A.M.2
-
101
-
-
0034661923
-
Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis
-
Yepes, M., Sandkvist, M., Wong, M.K. et al. Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis. Blood 2000, 96: 569-76.
-
(2000)
Blood
, vol.96
, pp. 569-576
-
-
Yepes, M.1
Sandkvist, M.2
Wong, M.K.3
-
102
-
-
0344990812
-
Catalase overexpression protects striatal neurons from transient focal cerebral ischemia
-
in press
-
Gu, P., Zhao, H., Yenari, M.A., Sapolsky, R.M. and Steinberg, G.K. Catalase overexpression protects striatal neurons from transient focal cerebral ischemia. Neuroreport 2003, in press.
-
(2003)
Neuroreport
-
-
Gu, P.1
Zhao, H.2
Yenari, M.A.3
Sapolsky, R.M.4
Steinberg, G.K.5
-
103
-
-
0141642104
-
Glutathione peroxidase overexpression inhibits cytochrome c release and pro-apoptotic mediators, to protect neurons from experimental stroke
-
Hoehn, B., Yenari, M., Sapolsky, R. and Steinberg, G. Glutathione peroxidase overexpression inhibits cytochrome c release and pro-apoptotic mediators, to protect neurons from experimental stroke. Stroke 2003, 34: 2489-94.
-
(2003)
Stroke
, vol.34
, pp. 2489-2494
-
-
Hoehn, B.1
Yenari, M.2
Sapolsky, R.3
Steinberg, G.4
-
104
-
-
0035085210
-
A synthetic inhibitor of p53 protects neurons against death induced ischemic and excitotoxic insults, and amyloid beta-peptide
-
Culmsee, C., Zhu, X., Yu, Q.S. et al. A synthetic inhibitor of p53 protects neurons against death induced ischemic and excitotoxic insults, and amyloid beta-peptide. J Neurochem 2001, 77: 220-8.
-
(2001)
J Neurochem
, vol.77
, pp. 220-228
-
-
Culmsee, C.1
Zhu, X.2
Yu, Q.S.3
-
105
-
-
0037352279
-
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
-
Cheng, T., Liu, D., Griffin, J.H. et al. Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective. Nat Med 2003, 9: 338-42.
-
(2003)
Nat Med
, vol.9
, pp. 338-342
-
-
Cheng, T.1
Liu, D.2
Griffin, J.H.3
-
106
-
-
0036969301
-
Adenovirus-mediated Bcl-X(L) expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice
-
Kilic, E., Hermann, D.M., Kugler, S. et al. Adenovirus-mediated Bcl-X(L) expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice. Neurobiol Dis 2002, 11: 275-84.
-
(2002)
Neurobiol Dis
, vol.11
, pp. 275-284
-
-
Kilic, E.1
Hermann, D.M.2
Kugler, S.3
-
107
-
-
0030848529
-
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
-
Xu, D.G., Crocker, S.J., Doucet, J.P. et al. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat Med 1997, 3: 997-1004.
-
(1997)
Nat Med
, vol.3
, pp. 997-1004
-
-
Xu, D.G.1
Crocker, S.J.2
Doucet, J.P.3
-
108
-
-
0035400124
-
Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptodc DNA fragmentation in transient cerebral ischemia and in neuronal cultures
-
Cao, G., Pei, W., Lan, J. et al. Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptodc DNA fragmentation in transient cerebral ischemia and in neuronal cultures. J Neurosci 2001, 21: 4678-90.
-
(2001)
J Neurosci
, vol.21
, pp. 4678-4690
-
-
Cao, G.1
Pei, W.2
Lan, J.3
-
109
-
-
0034131832
-
Protective effect ofa caspase inhibitor in models for cerebral ischemia in vitro and in vivo
-
Wiessner, C., Sauer, D., Alaimo, D. and Allegrini, P.R. Protective effect ofa caspase inhibitor in models for cerebral ischemia in vitro and in vivo. Cell Mol Biol (Noisy-legrand) 2000, 46: 53-62.
-
(2000)
Cell Mol Biol (Noisy-legrand)
, vol.46
, pp. 53-62
-
-
Wiessner, C.1
Sauer, D.2
Alaimo, D.3
Allegrini, P.R.4
-
110
-
-
0037095746
-
Transforming growthfactor-beta 1 increases bad phosphorylation and protects neurons against damage
-
Zhu, Y., Yang, G.Y., Ahlemeyer, B. et al. Transforming growthfactor-beta 1 increases bad phosphorylation and protects neurons against damage. J Neurosci 2002, 22: 3898-909.
-
(2002)
J Neurosci
, vol.22
, pp. 3898-3909
-
-
Zhu, Y.1
Yang, G.Y.2
Ahlemeyer, B.3
-
111
-
-
17944375146
-
Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons
-
Hayashi, K., Morishita, R., Nakagami, H. et al. Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Ther 2001, 8: 1167-73.
-
(2001)
Gene Ther
, vol.8
, pp. 1167-1173
-
-
Hayashi, K.1
Morishita, R.2
Nakagami, H.3
|