Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons

Gene Therapy

Volumn 8, Issue 15, 2001, Pages 1167-1173

  Hayashi, K ^a   Morishita, R ^b   Nakagami, H ^b   Yoshimura, S ^a   Hara, A ^a   Matsumoto, K ^b   Nakamura, T ^b   Ogihara, T ^b   Kaneda, Y ^b   Sakai, N ^a  

^a GIFU UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Delayed neuronal death; Gene therapy; HGF; Stroke

Indexed keywords

LIPOSOME; NEUROTROPHIC FACTOR; SCATTER FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERY OCCLUSION; ARTICLE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL DEATH; CELL NUCLEUS; CEREBROSPINAL FLUID; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; CYTOPLASM; FOREBRAIN; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; GERBIL; HIPPOCAMPUS; IN VIVO STUDY; MALE; NONHUMAN; PARAINFLUENZA VIRUS 1; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SUBARACHNOID SPACE;

ANIMALS; APOPTOSIS; BETA-GALACTOSIDASE; CEREBROVASCULAR ACCIDENT; GENE THERAPY; GERBILLINAE; HEPATOCYTE GROWTH FACTOR; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INJECTIONS, INTRALESIONAL; MALE; NEURONS; RESPIROVIRUS; SUBARACHNOID SPACE; TIME FACTORS; TRANSFECTION; TRANSLOCATION, GENETIC;

EID: 17944375146     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301498     Document Type: Article

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