Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

Journal of Neuroscience Research

Volumn 61, Issue 6, 2000, Pages 686-692

  Rosenbaum, Daniel M ^a   Gupta, Gaurav ^a   D'Amore, Jason ^a   Singh, Manjeet ^a   Weidenheim, Karen ^a   Zhang, Hong ^a   Kessler, John A ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Cerebral ischemia; Mice; Mutant; Rats

Indexed keywords

DNA FRAGMENT; FAS ANTIGEN; FAS LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MORPHOLOGY; MOUSE; NICK END LABELING; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; GENE EXPRESSION; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, MUTANT STRAINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034666684     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20000915)61:6<686::AID-JNR12>3.0.CO;2-7     Document Type: Article

References (36)

1. CD95-CD95L: Can the brain learn from the immune system?
2. Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
3. Attenuation of p53 expression protects against focal ischemic damage in transgenic mice
4. Correlation of p53- and fas (CD95)-mediated apoptosis in Alzheimer disease
5. Very delayed infarction after mild focal cerebral ischemia: A role for apoptosis
6. Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family
7. Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury
8. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
9. Fas-ligand-induced apoptosis as a mechanism of immune privilege
10. Inhibition of interleukin 1β converting enzyme family of proteases reduces ischemia and excitotoxic neuronal damage
11. Attenuation of transient focal cerebral ischemia injury in transgenic mice expressing a mutant ICE inhibitory protein
12. Cytokines and adhesion molecules in stroke and related diseases
13. Upregulation of Bax protein levels in neurons following cerebral ischemia
14. Temporal profile of in situ DNA fragmentation after transient MCA occlusion in the rat
15. Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats
16. Evidence supporting a role for programmed cell death in focal ischemia in rats
17. Reversible middle cerebral artery occlusion without craniectomy in rats
18. Difference in DNA fragmentation following transient cerebral or decapitation ischemia in rats
19. Fas antigen mRNA induction in postischemic murine brain
20. Localization of fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization
21. The soluble form of fas molecule is elevated in Parkinsonian brain tissues
22. The fas death factor
23. Fas antigen expression in brains of patients with Alzheimer-type dementia
24. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischernia vs apoptosis
25. Radiation and stress-induced apoptosis: A role for fas/fas ligand interactions
26. Pretreatment with intraventricular aurintricarboxylic acid decreases infarct size by inhibiting apoptosis following transient global ischemsia in gerbils
27. Caspases as treatment targets in stroke and neurodegenerative diseases
28. Inflammation and glial responses in ischemic brain lesions
29. Hydrogen peroxide induces up-regulation of fas in human endothelial cells
30. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
31. Intrathecal expression of proteins regulating apoptosis in acute stroke
32. Oxidative stress and hypoxia/reoxygenation trigger CD95 (APO-1/fas) ligand expression in microglial cells
33. The cDNA structure, expression, and chromosomal assignment of the mouse to antigen
34. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin 1β converting enzyme
35. Increased susceptibility to ischemic brain damage in transgenic mice overexpressing the amyloid precursor protein
36. Temporal profile of microglial response following transient (2 hr) middle cerebral artery occlusion