Thicker than blood: Conserved mechanisms in Drosophila and vertebrate hematopoiesis

Developmental Cell

Volumn 5, Issue 5, 2003, Pages 673-690

  Evans, Cory J ^a   Hartenstein, Volker ^a   Banerjee, Utpal ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; JANUS KINASE; LAMININ; NOTCH RECEPTOR; STAT PROTEIN; TRANSCRIPTION FACTOR; VASCULOTROPIN;

BLOOD CELL; BONE MARROW CELL; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL PROLIFERATION; DROSOPHILA; EMBRYO; ERYTHROCYTE; ERYTHROID CELL; GENE EXPRESSION; GENETIC CONSERVATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MEGAKARYOCYTE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VERTEBRATE;

ANIMALS; CELL LINEAGE; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HEMATOPOIESIS; HEMOCYTES; LYMPH NODES; MESODERM; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

DROSOPHILA MELANOGASTER; JANUS; MELANOGASTER; VERTEBRATA;

EID: 0242362740     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(03)00335-6     Document Type: Review

References (231)

1. Adya N. Castilla L.H. Liu P.P. Function of CBFβ/Bro proteins Semin. Cell Dev. Biol. 11 2000 361-368
2. Agaisse H. Petersen U.M. Boutros M. Mathey-Prevot B. Perrimon N. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury Dev. Cell 5 2003 441-450
3. Agalioti T. Lomvardas S. Parekh B. Yie J. Maniatis T. Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter Cell 103 2000 667-678
4. Akashi K. Traver D. Miyamoto T. Weissman I.L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages Nature 404 2000 193-197
5. Alfonso T.B. Jones B.W. gcm2 promotes glial cell differentiation and is required with glial cells missing for macrophage development in Drosophila Dev. Biol. 248 2002 369-383
6. Allman D. Aster J.C. Pear W.S. Notch signaling in hematopoiesis and early lymphocyte development Immunol. Rev. 187 2002 75-86
7. Altshuller Y. Copeland N.G. Gilbert D.J. Jenkins N.A. Frohman M.A. Gcm1, a mammalian homolog of Drosophila glial cells missing FEBS Lett. 393 1996 201-204
8. Anderson K.V. Bokla L. Nusslein-Volhard C. Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product Cell 42 1985 791-798
9. Armstrong J.A. Bieker J.J. Emerson B.M. A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro Cell 95 1998 93-104
10. Asha H. Nagy I. Kovacs G. Stetson D. Ando I. Dearolf C.R. Analysis of ras-induced overproliferation in Drosophila hemocytes Genetics 163 2003 203-215
11. Aster J.C. Pear W.S. Notch signaling in leukemia Curr. Opin. Hematol. 8 2001 237-244
12. Ayton P.M. Cleary M.L. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins Oncogene 20 2001 5695-5707
13. Badenhorst P. Voas M. Rebay I. Wu C. Biological functions of the ISWI chromatin remodeling complex NURF Genes Dev. 16 2002 3186-3198
14. Bangs P. Franc N. White K. Molecular mechanisms of cell death and phagocytosis in Drosophila Cell Death Differ. 7 2000 1027-1034
15. Bannister A.J. Kouzarides T. The CBP co-activator is a histone acetyltransferase Nature 384 1996 641-643
16. Bantignies F. Goodman R.H. Smolik S.M. The interaction between the coactivator dCBP and Modulo, a chromatin-associated factor, affects segmentation and melanotic tumor formation in Drosophila Proc. Natl. Acad. Sci. USA 99 2002 2895-2900
17. Bate M. Martinez Arias A. The Development of Drosophila melanogaster 1993 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
18. Beer J. Technau G.M. Campos-Ortega J.A. Lineage analysis of transplanted individual cells in embryos of Drosophila melanogaster. IV. Commitment and proliferative capabilities of mesodermal cells Rouxs Arch. Dev. Biol. 196 1987 222-230
19. Beg A.A. Sha W.C. Bronson R.T. Baltimore D. Constitutive NF-κ B activation, enhanced granulopoiesis, and neonatal lethality in I κ B α-deficient mice Genes Dev. 9 1995 2736-2746
20. Belvin M.P. Jin Y. Anderson K.V. Cactus protein degradation mediates Drosophila dorsal-ventral signaling Genes Dev. 9 1995 783-793
21. Bernardoni R. Vivancos V. Giangrande A. glide/gcm is expressed and required in the scavenger cell lineage Dev. Biol. 191 1997 118-130
22. Betz A. Lampen N. Martinek S. Young M.W. Darnell J.E.Jr. A Drosophila PIAS homologue negatively regulates stat92E Proc. Natl. Acad. Sci. USA 98 2001 9563-9568
23. Bodmer R. Venkatesh T.V. Heart development in Drosophila and vertebrates: conservation of molecular mechanisms Dev. Genet. 22 1998 181-186
24. Braun A. Lemaitre B. Lanot R. Zachary D. Meister M. Drosophila immunity: analysis of larval hemocytes by P-element-mediated enhancer trap Genetics 147 1997 623-634
25. Bromberg J. Stat proteins and oncogenesis J. Clin. Invest. 109 2002 1139-1142
26. Campos-Ortega J.A. Hartenstein V. The Embryonic Development of Drosophila melanogaster Second Edition 1997 Springer-Verlag Berlin, Heidelberg
27. Canon J. Banerjee U. In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein Genes Dev. 17 2003 838-843
28. Cantor A.B. Orkin S.H. Transcriptional regulation of erythropoiesis: an affair involving multiple partners Oncogene 21 2002 3368-3376
29. Cantor A.B. Katz S.G. Orkin S.H. Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation Mol. Cell. Biol. 22 2002 4268-4279
30. Carton Y. Nappi A.J. Immunogenetic aspects of the cellular immune response of Drosophila against parasitoids Immunogenetics 52 2001 157-164
31. Castanon I. Baylies M.K. A Twist in fate: evolutionary comparison of Twist structure and function Gene 287 2002 11-22
32. Chang A.N. Cantor A.B. Fujiwara Y. Lodish M.B. Droho S. Crispino J.D. Orkin S.H. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis Proc. Natl. Acad. Sci. USA 99 2002 9237-9242
33. Cho N.K. Keyes L. Johnson E. Heller J. Ryner L. Karim F. Krasnow M.A. Developmental control of blood cell migration by the Drosophila VEGF pathway Cell 108 2002 865-876
34. Chosa N. Fukumitsu T. Fujimoto K. Ohnishi E. Activation of prophenoloxidase A1 by an activating enzyme in Drosophila melanogaster Insect Biochem. Mol. Biol. 27 1997 61-68
35. Courey A.J. Jia S. Transcriptional repression: the long and the short of it Genes Dev. 15 2001 2786-2796
36. Cripps R.M. Olson E.N. Control of cardiac development by an evolutionarily conserved transcriptional network Dev. Biol. 246 2002 14-28
37. Crispino J.D. Lodish M.B. Thurberg B.L. Litovsky S.H. Collins T. Molkentin J.D. Orkin S.H. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors Genes Dev. 15 2001 839-844
38. Cuenot L. Etudes physiologiques sur les Orthopteres Arch. Biol. 14 1896 293-341
39. Daga A. Karlovich C.A. Dumstrei K. Banerjee U. Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1 Genes Dev. 10 1996 1194-1205
40. Davidson C.J. Tirouvanziam R. Lipsick J.S. Flow cytometry demonstrates a role for Dm-Myb in Drosophila blood cell function and proliferation Annu. Dros. Res. Conf. 44 2003 932B
41. Dearolf C.R. Fruit fly "leukemia." Biochim. Biophys. Acta 1377 1998 M13-M23
42. Deconinck A.E. Mead P.E. Tevosian S.G. Crispino J.D. Katz S.G. Zon L.I. Orkin S.H. FOG acts as a repressor of red blood cell development in Xenopus Development 127 2000 2031-2040
43. De Gregorio E. Han S.J. Lee W.J. Baek M.J. Osaki T. Kawabata S. Lee B.L. Iwanaga S. Lemaitre B. Brey P.T. An immune-responsive Serpin regulates the melanization cascade in Drosophila Dev. Cell 3 2002 581-592
44. Dimarcq J.L. Imler J.L. Lanot R. Ezekowitz R.A. Hoffmann J.A. Janeway C.A. Lagueux M. Treatment of l(2)mbn Drosophila tumorous blood cells with the steroid hormone ecdysone amplifies the inducibility of antimicrobial peptide gene expression Insect Biochem. Mol. Biol. 27 1997 877-886
45. Duchek P. Somogyi K. Jekely G. Beccari S. Rorth P. Guidance of cell migration by the Drosophila PDGF/VEGF receptor Cell 107 2001 17-26
46. Duvic B. Hoffmann J.A. Meister M. Royet J. Notch signaling controls lineage specification during Drosophila larval hematopoiesis Curr. Biol. 12 2002 1923-1927
47. Dzierzak E. Embryonic beginnings of definitive hematopoietic stem cells Ann. NY Acad. Sci. 872 1999 256-262 discussion 262-254
48. Elagib K.E. Racke F.K. Mogass M. Khetawat R. Delehanty L.L. Goldfarb A.N. RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation Blood 101 2003 4333-4341
49. Elfring L.K. Daniel C. Papoulas O. Deuring R. Sarte M. Moseley S. Beek S.J. Waldrip W.R. Daubresse G. DePace A. et al. Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SWI2/SNF2 Genetics 148 1998 251-265
50. Elrod-Erickson M. Mishra S. Schneider D. Interactions between the cellular and humoral immune responses in Drosophila Curr. Biol. 10 2000 781-784
51. el Shatoury H.H. The structure of the lymph glands of Drosophila larvae Roux Arch. EntwMech. Organ. 147 1955 489-495
52. Fadok V.A. Bratton D.L. Rose D.M. Pearson A. Ezekewitz R.A. Henson P.M. A receptor for phosphatidylserine-specific clearance of apoptotic cells Nature 405 2000 85-90
53. Fehling H.J. Gilfillan S. Ceredig R. α β/γ δ lineage commitment in the thymus of normal and genetically manipulated mice Adv. Immunol. 71 1999 1-76
54. Ferrara N. Gerber H.P. LeCouter J. The biology of VEGF and its receptors Nat. Med. 9 2003 669-676
55. Fessler L.I. Nelson R.E. Fessler J.H. Drosophila extracellular matrix Methods Enzymol. 245 1994 271-294
56. Fisher A.G. Cellular identity and lineage choice Nat. Rev. Immunol. 2 2002 977-982
57. Flores G.V. Daga A. Kalhor H.R. Banerjee U. Lozenge is expressed in pluripotent precursor cells and patterns multiple cell types in the Drosophila eye through the control of cell-specific transcription factors Development 125 1998 3681-3687
58. Fossett N. Zhang Q. Gajewski K. Choi C.Y. Kim Y. Schulz R.A. The multitype zinc-finger protein U-shaped functions in heart cell specification in the Drosophila embryo Proc. Natl. Acad. Sci. USA 97 2000 7348-7353
59. Fossett N. Tevosian S.G. Gajewski K. Zhang Q. Orkin S.H. Schulz R.A. The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila Proc. Natl. Acad. Sci. USA 98 2001 7342-7347
60. Fossett N. Hyman K. Gajewski K. Orkin S.H. Schulz R.A. Combinatorial interactions of serpent, lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis Proc. Natl. Acad. Sci. USA 100 2003 11451-11456
61. Franc N.C. Dimarcq J.L. Lagueux M. Hoffmann J. Ezekowitz R.A. Croquemort, a novel Drosophila hemocyte/macrophage receptor that recognizes apoptotic cells Immunity 4 1996 431-443
62. Frasch M. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo Nature 374 1995 464-467
63. Freeman M.R. Delrow J. Kim J. Johnson E. Doe C.Q. Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function Neuron 38 2003 567-580
64. Fujiwara, Y., Chang, A.N., Williams, A.M., and Orkin, S.H. (2003). Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood, in press. Published online September 22, 2003.
65. Gabrilovich D.I. Chen H.L. Girgis K.R. Cunningham H.T. Meny G.M. Nadaf S. Kavanaugh D. Carbone D.P. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells Nat. Med. 2 1996 1096-1103
66. Garzino V. Pereira A. Laurenti P. Graba Y. Levis R.W. Le Parco Y. Pradel J. Cell lineage-specific expression of modulo, a dose-dependent modifier of variegation in Drosophila EMBO J. 11 1992 4471-4479
67. Gateff E. Tumor-suppressor genes, hematopoietic malignancies and other hematopoietic disorders of Drosophila melanogaster Ann. N Y Acad. Sci. 712 1994 260-279
68. Gehring W.J. The genetic control of eye development and its implications for the evolution of the various eye-types Int. J. Dev. Biol. 46 2002 65-73
69. Georgopoulos K. Haematopoietic cell-fate decisions, chromatin regulation and ikaros Nat. Rev. Immunol. 2 2002 162-174
70. Gerber H.P. Malik A.K. Solar G.P. Sherman D. Liang X.H. Meng G. Hong K. Marsters J.C. Ferrara N. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism Nature 417 2002 954-958
71. Gerhart J. Kirschner M. Cells, Embryos and Evolution: Toward a Cellular and Developmental Understanding of Phenotypic Variation and Evolutionary Adaptability 1997 Blackwell Science Boston, MA
72. Gerondakis S. Grossmann M. Nakamura Y. Pohl T. Grumont R. Genetic approaches in mice to understand Rel/NF-κB and IκB function: transgenics and knockouts Oncogene 18 1999 6888-6895
73. Gerttula S. Jin Y.S. Anderson K.V. Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation Genetics 119 1988 123-133
74. Ghelelovitch S. Melanotic tumors in Drosophila melanogaster Natl. Cancer Inst. Monogr. 31 1969 263-275
75. Gisselbrecht S. Skeath J.B. Doe C.Q. Michelson A.M. heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo Genes Dev. 10 1996 3003-3017
76. Godin I. Cumano A. The hare and the tortoise: an embryonic haematopoietic race Nat. Rev. Immunol. 2 2002 593-604
77. Govind S. Control of development and immunity by rel transcription factors in Drosophila Oncogene 18 1999 6875-6887
78. Gunther T. Chen Z.F. Kim J. Priemel M. Rueger J.M. Amling M. Moseley J.M. Martin T.J. Anderson D.J. Karsenty G. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone Nature 406 2000 199-203
79. Gupta A.P. Hemocyte types: their structures, synonymies, interrelationships, and taxonomic significance. In Gupta A.P. (Ed.), Insect Hemocyte 1979 Cambridge University Press Cambridge, UK 85-127.pp
80. Haenlin M. Cubadda Y. Blondeau F. Heitzler P. Lutz Y. Simpson P. Ramain P. Transcriptional activity of pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila Genes Dev. 11 1997 3096-3108
81. Hanratty W.P. Dearolf C.R. The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus Mol. Gen. Genet. 238 1993 33-37
82. Hanratty W.P. Ryerse J.S. A genetic melanotic neoplasm of Drosophila melanogaster Dev. Biol. 83 1981 238-249
83. Harrison D.A. Binari R. Nahreini T.S. Gilman M. Perrimon N. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects EMBO J. 14 1995 2857-2865
84. Hashimoto C. Hudson K.L. Anderson K.V. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein Cell 52 1988 269-279
85. Hattori K. Dias S. Heissig B. Hackett N.R. Lyden D. Tateno M. Hicklin D.J. Zhu Z. Witte L. Crystal R.G. et al. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells J. Exp. Med. 193 2001 1005-1014
86. Haughn L. Hawley R.G. Morrison D.K. von Boehmer H. Hockenbery D.M. BCL-2 and BCL-XL restrict lineage choice during hematopoietic differentiation J. Biol. Chem. 278 2003 25158-25165
87. Heino T.I. Karpanen T. Wahlstrom G. Pulkkinen M. Eriksson U. Alitalo K. Roos C. The Drosophila VEGF receptor homolog is expressed in hemocytes Mech. Dev. 109 2001 69-77
88. Herbomel P. Thisse B. Thisse C. Ontogeny and behaviour of early macrophages in the zebrafish embryo Development 126 1999 3735-3745
89. Hess J.L. Yu B.D. Li B. Hanson R. Korsmeyer S.J. Defects in yolk sac hematopoiesis in Mll-null embryos Blood 90 1997 1799-1806
90. Hetru C. Troxler L. Hoffmann J.A. Drosophila melanogaster antimicrobial defense J. Infect. Dis. 187 Suppl 2 2003 S327-S334
91. Hollande A.C. Contribution a l'etude du sang des Coleopteres Arch. Zool. Exp. Gen. (Ser 5) 21 1909 271-294
92. Holmes M. Turner J. Fox A. Chisholm O. Crossley M. Chong B. hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation J. Biol. Chem. 274 1999 23491-23498
93. Holz A. Bossinger B. Strasser T. Janning W. Klapper R. The two origins of hemocytes in Drosophila Development 130 2003 4955-4962
94. Hosoya T. Takizawa K. Nitta K. Hotta Y. glial cells missing: a binary switch between neuronal and glial determination in Drosophila Cell 82 1995 1025-1036
95. Hou S.X. Zheng Z. Chen X. Perrimon N. The Jak/STAT pathway in model organisms: emerging roles in cell movement Dev. Cell 3 2002 765-778
96. Ip Y.T. Levine M. Molecular genetics of Drosophila immunity Curr. Opin. Genet. Dev. 4 1994 672-677
97. Iritani B.M. Forbush K.A. Farrar M.A. Perlmutter R.M. Control of B cell development by Ras-mediated activation of Raf EMBO J. 16 1997 7019-7031
98. Jones B.W. Fetter R.D. Tear G. Goodman C.S. glial cells missing: a genetic switch that controls glial versus neuronal fate Cell 82 1995 1013-1023
99. Kaminker J.S. Singh R. Lebestky T. Yan H. Banerjee U. Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila development Development 128 2001 2639-2648
100. Kammerer M. Giangrande A. Glide2, a second glial promoting factor in Drosophila melanogaster EMBO J. 20 2001 4664-4673
101. Karanu F.N. Murdoch B. Gallacher L. Wu D.M. Koremoto M. Sakano S. Bhatia M. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells J. Exp. Med. 192 2000 1365-1372
102. Katz S.G. Cantor A.B. Orkin S.H. Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo Mol. Cell. Biol. 22 2002 3121-3128
103. Kieslinger M. Woldman I. Moriggl R. Hofmann J. Marine J.C. Ihle J.N. Beug H. Decker T. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation Genes Dev. 14 2000 232-244
104. Kiger Jr. J.A. Natzle J.E. Green M.M. Hemocytes are essential for wing maturation in Drosophila melanogaster Proc. Natl. Acad. Sci. USA 98 2001 10190-10195
105. Kim J. Jones B.W. Zock C. Chen Z. Wang H. Goodman C.S. Anderson D.J. Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing Proc. Natl. Acad. Sci. USA 95 1998 12364-12369
106. Kitabayashi I. Yokoyama A. Shimizu K. Ohki M. Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation EMBO J. 17 1998 2994-3004
107. Klapper R. Holz A. Janning W. Fate map and cell lineage relationships of thoracic and abdominal mesodermal anlagen in Drosophila melanogaster Mech. Dev. 71 1998 77-87
108. Kmita M. Duboule D. Organizing axes in time and space; 25 years of colinear tinkering Science 301 2003 331-333
109. Kondo M. Weissman I.L. Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow Cell 91 1997 661-672
110. Kondo M. Wagers A.J. Manz M.G. Prohaska S.S. Scherer D.C. Beilhack G.F. Shizuru J.A. Weissman I.L. Biology of hematopoietic stem cells and progenitors: implications for clinical application Annu. Rev. Immunol. 21 2003 759-806
111. Kowenz-Leutz E. Leutz A. A C/EBP β isoform recruits the SWI/SNF complex to activate myeloid genes Mol. Cell 4 1999 735-743
112. Kumano K. Chiba S. Shimizu K. Yamagata T. Hosoya N. Saito T. Takahashi T. Hamada Y. Hirai H. Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression Blood 98 2001 3283-3289
113. Kumano K. Chiba S. Kunisato A. Sata M. Saito T. Nakagami-Yamaguchi E. Yamaguchi T. Masuda S. Shimizu K. Takahashi T. et al. Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells Immunity 18 2003 699-711
114. Kung A.L. Rebel V.I. Bronson R.T. Ch'ng L.E. Sieff C.A. Livingston D.M. Yao T.P. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP Genes Dev. 14 2000 272-277
115. Kurdistani S.K. Grunstein M. Histone acetylation and deacetylation in yeast Nat. Rev. Mol. Cell Biol. 4 2003 276-284
116. Kurucz E. Zettervall C.J. Sinka R. Vilmos P. Pivarcsi A. Ekengren S. Hegedus Z. Ando I. Hultmark D. Hemese, a hemocyte-specific transmembrane protein, affects the cellular immune response in Drosophila Proc. Natl. Acad. Sci. USA 100 2003 2622-2627
117. Kwon E.J. Park H.S. Kim Y.S. Oh E.J. Nishida Y. Matsukage A. Yoo M.A. Yamaguchi M. Transcriptional regulation of the Drosophila raf proto-oncogene by Drosophila STAT during development and in immune response J. Biol. Chem. 275 2000 19824-19830
118. Lacronique V. Boureux A. Valle V.D. Poirel H. Quang C.T. Mauchauffe M. Berthou C. Lessard M. Berger R. Ghysdael J. Bernard O.A. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia Science 278 1997 1309-1312
119. Lanot R. Zachary D. Holder F. Meister M. Postembryonic hematopoiesis in Drosophila Dev. Biol. 230 2001 243-257
120. Lebestky, T.J. (2001). Specification of hematopoietic lineage in Drosophila melanogaster. PhD thesis, University of California, Los Angeles.
121. Lebestky T. Chang T. Hartenstein V. Banerjee U. Specification of Drosophila hematopoietic lineage by conserved transcription factors Science 288 2000 146-149
122. Lebestky T. Jung S.H. Banerjee U. A Serrate-expressing signaling center controls Drosophila hematopoiesis Genes Dev. 17 2003 348-353
123. Lee C.H. Murphy M.R. Lee J.S. Chung J.H. Targeting a SWI/SNF-related chromatin remodeling complex to the β-globin promoter in erythroid cells Proc. Natl. Acad. Sci. USA 96 1999 12311-12315
124. Lemaitre B. Meister M. Govind S. Georgel P. Steward R. Reichhart J.M. Hoffmann J.A. Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila EMBO J. 14 1995 536-545
125. Lessard J. Sauvageau G. Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis Exp. Hematol. 31 2003 567-585
126. Letting D.L. Rakowski C. Weiss M.J. Blobel G.A. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1 Mol. Cell. Biol. 23 2003 1334-1340
127. Levanon D. Goldstein R.E. Bernstein Y. Tang H. Goldenberg D. Stifani S. Paroush Z. Groner Y. Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors Proc. Natl. Acad. Sci. USA 95 1998 11590-11595
128. Li L.H. Gergen J.P. Differential interactions between Brother proteins and Runt domain proteins in the Drosophila embryo and eye Development 126 1999 3313-3322
129. Ligoxygakis P. Pelte N. Ji C. Leclerc V. Duvic B. Belvin M. Jiang H. Hoffmann J.A. Reichhart J.M. A serpin mutant links Toll activation to melanization in the host defence of Drosophila EMBO J. 21 2002 6330-6337
130. Lindsell C.E. Shawber C.J. Boulter J. Weinmaster G. Jagged: a mammalian ligand that activates Notch1 Cell 80 1995 909-917
131. Lowry J.A. Atchley W.R. Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain J. Mol. Evol. 50 2000 103-115
132. Luo H. Hanratty W.P. Dearolf C.R. An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects EMBO J. 14 1995 1412-1420
133. Luo H. Rose P.E. Roberts T.M. Dearolf C.R. The Hopscotch Jak kinase requires the Raf pathway to promote blood cell activation and differentiation in Drosophila Mol. Genet. Genomics 267 2002 57-63
134. Lutterbach B. Hiebert S.W. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation Gene 245 2000 223-235
135. Maduro M.F. Rothman J.H. Making worm guts: the gene regulatory network of the Caenorhabditis elegans endoderm Dev. Biol. 246 2002 68-85
136. Martin G. Making a vertebrate limb: new players enter from the wings Bioessays 23 2001 865-868
137. Mikula M. Schreiber M. Husak Z. Kucerova L. Ruth J. Wieser R. Zatloukal K. Beug H. Wagner E.F. Baccarini M. Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene EMBO J. 20 2001 1952-1962
138. Miller R.W. Rubinstein J.H. Tumors in Rubinstein-Taybi syndrome Am. J. Med. Genet. 56 1995 112-115
139. Munier A.I. Doucet D. Perrodou E. Zachary D. Meister M. Hoffmann J.A. Janeway Jr. C.A. Lagueux M. PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae EMBO Rep. 3 2002 1195-1200
140. Murray M.A. Fessler L.I. Palka J. Changing distributions of extracellular matrix components during early wing morphogenesis in Drosophila Dev. Biol. 168 1995 150-165
141. Nappi A.J. Inhibition by parasites of melanotic tumour formation in Drosophila melanogaster Nature 255 1975 402-404
142. Nappi A.J. Vass E. Hydrogen peroxide production in immune-reactive Drosophila melanogaster J. Parasitol. 84 1998 1150-1157
143. Nappi A.J. Vass E. Frey F. Carton Y. Nitric oxide involvement in Drosophila immunity Nitric Oxide 4 2000 423-430
144. Neubauer H. Cumano A. Muller M. Wu H. Huffstadt U. Pfeffer K. Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis Cell 93 1998 397-409
145. Ogawa H. Ueda T. Aoyama T. Aronheim A. Nagata S. Fukunaga R. A SWI2/SNF2-type ATPase/helicase protein, mDomino, interacts with myeloid zinc finger protein 2A (MZF-2A) to regulate its transcriptional activity Genes Cells 8 2003 325-339
146. Ohinata H. Tochinai S. Katagiri C. Occurrence of nonlymphoid leukocytes that are not derived from blood islands in Xenopus laevis larvae Dev. Biol. 141 1990 123-129
147. Okuda T. van Deursen J. Hiebert S.W. Grosveld G. Downing J.R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis Cell 84 1996 321-330
148. Orkin S.H. Shivdasani R.A. Fujiwara Y. McDevitt M.A. Transcription factor GATA-1 in megakaryocyte development Stem Cells 16 Suppl 2 1998 79-83
149. Parganas E. Wang D. Stravopodis D. Topham D.J. Marine J.C. Teglund S. Vanin E.F. Bodner S. Colamonici O.R. van Deursen J.M. et al. Jak2 is essential for signaling through a variety of cytokine receptors Cell 93 1998 385-395
150. Patient R.K. McGhee J.D. The GATA family (vertebrates and invertebrates) Curr. Opin. Genet. Dev. 12 2002 416-422
151. Peeples E.E. Geisler A. Whitcraft C.J. Oliver C. Comparative studies of phenol oxidase activity during pupal development of three lozenge mutants (lzs, lz, lzk) of Drosophila melanogaster Genetics 62 1969 161-170
152. Peeters P. Raynaud S.D. Cools J. Wlodarska I. Grosgeorge J. Philip P. Monpoux F. Van Rompaey L. Baens M. Van den Berghe H. Marynen P. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia Blood 90 1997 2535-2540
153. Perrimon N. Mahowald A.P. l(1)hopscotch, a larval-pupal zygotic lethal with a specific maternal effect on segmentation in Drosophila Dev. Biol. 118 1986 28-41
154. Petrij F. Giles R.H. Dauwerse H.G. Saris J.J. Hennekam R.C. Masuno M. Tommerup N. van Ommen G.J. Goodman R.H. Peters D.J. et al. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP Nature 376 1995 348-351
155. Pevny L. Simon M.C. Robertson E. Klein W.H. Tsai S.F. D'Agati V. Orkin S.H. Costantini F. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 Nature 349 1991 257-260
156. Pui J.C. Allman D. Xu L. DeRocco S. Karnell F.G. Bakkour S. Lee J.Y. Kadesch T. Hardy R.R. Aster J.C. Pear W.S. Notch1 expression in early lymphopoiesis influences B versus T lineage determination Immunity 11 1999 299-308
157. Qiu P. Pan P.C. Govind S. A role for the Drosophila Toll/Cactus pathway in larval hematopoiesis Development 125 1998 1909-1920
158. Radtke F. Wilson A. Stark G. Bauer M. van Meerwijk J. MacDonald H.R. Aguet M. Deficient T cell fate specification in mice with an induced inactivation of Notch1 Immunity 10 1999 547-558
159. Radtke F. Wilson A. Ernst B. MacDonald H.R. The role of Notch signaling during hematopoietic lineage commitment Immunol. Rev. 187 2002 65-74
160. Ramet M. Pearson A. Manfruelli P. Li X. Koziel H. Gobel V. Chung E. Krieger M. Ezekowitz R.A. Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria Immunity 15 2001 1027-1038
161. Ramet M. Lanot R. Zachary D. Manfruelli P. JNK signaling pathway is required for efficient wound healing in Drosophila Dev. Biol. 241 2002a 145-156
162. Ramet M. Manfruelli P. Pearson A. Mathey-Prevot B. Ezekowitz R.A. Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli Nature 416 2002b 644-648
163. Rane S.G. Reddy E.P. JAKs, STATs and Src kinases in hematopoiesis Oncogene 21 2002 3334-3358
164. Ratcliffe N.A. Rowley A.F. Role of hemocytes in defense against biological agents. In Gupta A.P. (Ed.), Insect Hemocytes 1979 Cambridge University Press Cambridge, UK 331-414.pp
165. Rayet B. Gelinas C. Aberrant rel/nfkb genes and activity in human cancer Oncogene 18 1999 6938-6947
166. Rehorn K.P. Thelen H. Michelson A.M. Reuter R. A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila Development 122 1996 4023-4031
167. Remillieux-Leschelle N. Santamaria P. Randsholt N.B. Regulation of larval hematopoiesis in Drosophila melanogaster: a role for the multi sex combs gene Genetics 162 2002 1259-1274
168. Rizki T.M. Blood cells of Drosophila as related to metamorphosis. In Campbell F.L. (Ed.), Physiology of Insect Development 1956 Chicago University Press Chicago, IL 91-94.pp
169. Rizki T.M. Experimental analysis of hemocyte morphology in insects Am. Zool. 2 1962 247-256
170. Rizki T.M. The circulatory system and associated cells and tissues. In Ashburner M. Wright T.R.F. (Eds.), The Genetics and Biology of Drosophila 1978 Academic Press New York, London
171. Rizki R.M. Rizki T.M. Basement membrane abnormalities in melanotic tumor formation of Drosophila Experientia 30 1974 543-546
172. Rizki R.M. Rizki T.M. Cell interactions in the differentiation of a melanotic tumor in Drosophila Differentiation 12 1979 167-178
173. Rizki T.M. Rizki R.M. Properties of the larval hemocytes of Drosophila melanogaster Experientia 36 1980 1223-1226
174. Rizki T.M. Rizki R.M. Alleles of lz as suppressors of the Bc-phene in Drosophila melanogaster Genetics 97 1981 S90
175. Rizki T.M. Rizki R.M. Paracrystalline inclusions of D. melanogaster hemocytes have prophenoloxidases Genetics 110 1985 S98
176. Rizki T.M. Rizki R.M. Lamellocyte differentiation in Drosophila larvae parasitized by Leptopilina Dev. Comp. Immunol. 16 1992 103-110
177. Rizki T.M. Rizki R.M. Grell E.H. A mutant affecting the crystal cells in Drosophila melanogaster Rouxs Arch. Dev. Biol. 188 1980 91-99
178. Robertson C.W. The metamorphosis of Drosophila melanogaster, including an accurately timed account of the principal morphological changes J. Morphol. 59 1936 351-399
179. Robey E. Chang D. Itano A. Cado D. Alexander H. Lans D. Weinmaster G. Salmon P. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages Cell 87 1996 483-492
180. Roos E. Bjorklund G. Engstrom Y. In vivo regulation of tissue-specific and LPS-inducible expression of the Drosophila Cecropin genes Insect Mol. Biol. 7 1998 51-62
181. Rosetto M. Engstrom Y. Baldari C.T. Telford J.L. Hultmark D. Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line Biochem. Biophys. Res. Commun. 209 1995 111-116
182. Rugendorff A.E. Younossi-Hartenstein A. Hartenstein V. Embryonic origin and differentiation of the Drosophila heart Rouxs Arch. Dev. Biol. 203 1994 266-280
183. Ruhf M.L. Braun A. Papoulas O. Tamkun J.W. Randsholt N. Meister M. The domino gene of Drosophila encodes novel members of the SWI2/SNF2 family of DNA-dependent ATPases, which contribute to the silencing of homeotic genes Development 128 2001 1429-1441
184. Russo J. Dupas S. Frey F. Carton Y. Brehelin M. Insect immunity: early events in the encapsulation process of parasitoid (Leptopilina boulardi) eggs in resistant and susceptible strains of Drosophila Parasitology 112 1996 135-142
185. Saito T. Chiba S. Ichikawa M. Kunisato A. Asai T. Shimizu K. Yamaguchi T. Yamamoto G. Seo S. Kumano K. et al. Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development Immunity 18 2003 675-685
186. Sam S. Leise W. Hoshizaki D.K. The serpent gene is necessary for progression through the early stages of fat-body development Mech. Dev. 60 1996 197-205
187. Samakovlis C. Kimbrell D.A. Kylsten P. Engstrom A. Hultmark D. The immune response in Drosophila: pattern of cecropin expression and biological activity EMBO J. 9 1990 2969-2976
188. Sasaki K. Yagi H. Bronson R.T. Tominaga K. Matsunashi T. Deguchi K. Tani Y. Kishimoto T. Komori T. Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor β Proc. Natl. Acad. Sci. USA 93 1996 12359-12363
189. Schneider D.S. Hudson K.L. Lin T.Y. Anderson K.V. Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo Genes Dev. 5 1991 797-807
190. Schreiber J. Riethmacher-Sonnenberg E. Riethmacher D. Tuerk E.E. Enderich J. Bosl M.R. Wegner M. Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa Mol. Cell. Biol. 20 2000 2466-2474
191. Schwaller J. Parganas E. Wang D. Cain D. Aster J.C. Williams I.R. Lee C.K. Gerthner R. Kitamura T. Frantsve J. et al. Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2 Mol. Cell 6 2000 693-704
192. Sears H.C. Kennedy C.J. Garrity P.A. Macrophage-mediated corpse engulfment is required for normal Drosophila CNS morphogenesis Development 130 2003 3557-3565
193. Shivdasani R.A. Fujiwara Y. McDevitt M.A. Orkin S.H. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development EMBO J. 16 1997 3965-3973
194. Shrestha R. Gateff E. Ultrastructure and cytochemistry of the cell types in the larval hematopoietic organs and hemolymph of Drosophila melanogaster Dev. Growth Differ. 24 1982 65-82
195. Siddall N.A. Behan K.J. Crew J.R. Cheung T.L. Fair J.A. Batterham P. Pollock J.A. Mutations in lozenge and D-Pax2 invoke ectopic patterned cell death in the developing Drosophila eye using distinct mechanisms Dev. Genes Evol. 213 2003 107-119
196. Silverman N. Maniatis T. NF-κB signaling pathways in mammalian and insect innate immunity Genes Dev. 15 2001 2321-2342
197. Silvers M. Hanratty W.P. Alterations in the production of hemocytes due to a neoplastic mutation of Drosophila melanogaster J. Invertebr. Pathol. 44 1984 324-328
198. Soderhall K. Cerenius L. Role of the prophenoloxidase-activating system in invertebrate immunity Curr. Opin. Immunol. 10 1998 23-28
199. Sorrentino R.P. Carton Y. Govind S. Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated Dev. Biol. 243 2002 65-80
200. Speck N.A. Gilliland D.G. Core-binding factors in haematopoiesis and leukaemia Nat. Rev. Cancer 2 2002 502-513
201. Stark, M.B., and Marshall, A.K. (1930). The blood-forming organ of the larva of Drosophila melanogaster. Bell Telephone System Tech. Pub. Monogr. 1931, 1204-1206.
202. Struhl K. Histone acetylation and transcriptional regulatory mechanisms Genes Dev. 12 1998 599-606
203. Sundqvist A. Sollerbrant K. Svensson C. The carboxy-terminal region of adenovirus E1A activates transcription through targeting of a C-terminal binding protein-histone deacetylase complex FEBS Lett. 429 1998 183-188
204. Svensson E.C. Tufts R.L. Polk C.E. Leiden J.M. Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes Proc. Natl. Acad. Sci. USA 96 1999 956-961
205. Takahashi K. Naito M. Development, differentiation, and proliferation of macrophages in the rat yolk sac Tissue Cell 25 1993 351-362
206. Takahashi K. Yamamura F. Naito M. Differentiation, maturation, and proliferation of macrophages in the mouse yolk sac: a light-microscopic, enzyme-cytochemical, immunohistochemical, and ultrastructural study J. Leukoc. Biol. 45 1989 87-96
207. Tepass U. Fessler L.I. Aziz A. Hartenstein V. Embryonic origin of hemocytes and their relationship to cell death in Drosophila Development 120 1994 1829-1837
208. Tevosian S.G. Deconinck A.E. Cantor A.B. Rieff H.I. Fujiwara Y. Corfas G. Orkin S.H. FOG-2: a novel gata-family cofactor related to multitype zinc-finger proteins friend of GATA-1 and u-shaped Proc. Natl. Acad. Sci. USA 96 1999 950-955
209. Ting C.N. Olson M.C. Barton K.P. Leiden J.M. Transcription factor GATA-3 is required for development of the T-cell lineage Nature 384 1996 474-478
210. Traver D. Zon L.I. Walking the walk: migration and other common themes in blood and vascular development Cell 108 2002 731-734
211. Tsai F.Y. Keller G. Kuo F.C. Weiss M. Chen J. Rosenblatt M. Alt F.W. Orkin S.H. An early haematopoietic defect in mice lacking the transcription factor GATA-2 Nature 371 1994 221-226
212. Tsang A.P. Visvader J.E. Turner C.A. Fujiwara Y. Yu C. Weiss M.J. Crossley M. Orkin S.H. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation Cell 90 1997 109-119
213. Tsang A.P. Fujiwara Y. Hom D.B. Orkin S.H. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG Genes Dev. 12 1998 1176-1188
214. Turner J. Crossley M. Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators EMBO J. 17 1998 5129-5140
215. Tzou P. De Gregorio E. Lemaitre B. How Drosophila combats microbial infection: a model to study innate immunity and host-pathogen interactions Curr. Opin. Microbiol. 5 2002 102-110
216. Varnum-Finney B. Purton L.E. Yu M. Brashem-Stein C. Flowers D. Staats S. Moore K.A. Le Roux I. Mann R. Gray G. et al. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells Blood 91 1998 4084-4091
217. Vincent S. Vonesch J.L. Giangrande A. Glide directs glial fate commitment and cell fate switch between neurones and glia Development 122 1996 131-139
218. Walker L. Carlson A. Tan-Pertel H.T. Weinmaster G. Gasson J. The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse Stem Cells 19 2001 543-552
219. Waltzer L. Bataille L. Peyrefitte S. Haenlin M. Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis EMBO J. 21 2002 5477-5486
220. Wang Q. Stacy T. Binder M. Marin-Padilla M. Sharpe A.H. Speck N.A. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis Proc. Natl. Acad. Sci. USA 93 1996a 3444-3449
221. Wang Q. Stacy T. Miller J.D. Lewis A.F. Gu T.L. Huang X. Bushweller J.H. Bories J.C. Alt F.W. Ryan G. et al. The CBFβ subunit is essential for CBFα2 (AML1) function in vivo Cell 87 1996b 697-708
222. Washburn T. Schweighoffer E. Gridley T. Chang D. Fowlkes B.J. Cado D. Robey E. Notch activity influences the αβ versus γδ T cell lineage decision Cell 88 1997 833-843
223. Wegner M. Riethmacher D. Chronicles of a switch hunt: gcm genes in development Trends Genet. 17 2001 286-290
224. Wigglesworth, V.B. (1939). The Principles of Insect Physiology, First Edition (Methuen, London).
225. Wilson A. MacDonald H.R. Radtke F. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus J. Exp. Med. 194 2001 1003-1012
226. Wu X. Golden K. Bodmer R. Heart development in Drosophila requires the segment polarity gene wingless Dev. Biol. 169 1995 619-628
227. Yagi H. Deguchi K. Aono A. Tani Y. Kishimoto T. Komori T. Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice Blood 92 1998 108-117
228. Yasothornsrikul S. Davis W.J. Cramer G. Kimbrell D.A. Dearolf C.R. viking: identification and characterization of a second type IV collagen in Drosophila Gene 198 1997 17-25
229. Yeager J.F. The blood picture of the southern armyworm (Prodenia eridania) J. Agric. Res. 71 1945 1-40
230. Zhang W. Kadam S. Emerson B.M. Bieker J.J. Site-specific acetylation by p300 or CREB binding protein regulates erythroid Kruppel-like factor transcriptional activity via its interaction with the SWI-SNF complex Mol. Cell. Biol. 21 2001 2413-2422
231. Zhou Z. Hartwieg E. Horvitz H.R. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans Cell 104 2001 43-56