The role of Notch signaling during hematopoietic lineage commitment

Immunological Reviews

Volumn 187, Issue , 2002, Pages 65-74

  Radtke, Freddy ^a   Wilson, Anne ^a   Ernst, Bettina ^a   MacDonald, H Robson ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; NOTCH RECEPTOR;

BONE MARROW; CELL FUNCTION; CELL LINEAGE; HEMATOPOIESIS; HEMATOPOIETIC CELL; HUMAN; LYMPHATIC SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; HEMATOPOIESIS; HUMANS; LYMPHOCYTES; MEMBRANE PROTEINS; MYELOID CELLS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 0036749748     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2002.18706.x     Document Type: Review

References (67)

1. Artavanis-Tsakonas S, Matsuno K, Fortini Me. Notch signaling. Science 1995;268:225-232.
2. Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 1999;284:770-776.
3. Mohr OL. Character changes caused by mutation of an entire region of chromosome in Drosophila. Genetics 1919;4:275-282.
4. Weinmaster G, Roberts VJ, Lemke G. A homolog of Drosophila Notch expressed during mammalian development. Development 1991;113:199-205.
5. Weinmaster G, Roberts VJ, Lemke G. Notch2: a second mammalian Notch gene. Development 1992;116:931-941.
6. Reaume AG, Conlon RA, Zirngibl R, Yamaguchi TP, Rossant J. Expression analysis of a Notch homologue in the mouse embryo. Dev Biol 1992;154:377-387.
7. del Amo FF, Gendron-Maguire M, Swiatek PJ, Jenkins NA, Copeland NG, Gridley T. Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila Notch. Genomics 1993;15:259-264.
8. Lardelli M, Lendahl U. Motch A and motch B - two mouse Notch homologues coexpressed in a wide variety of tissues. Exp Cell Res 1993;204:364-372.
9. Lardelli M, Dahlstrand J, Lendahl U. The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech Dev 1994;46:123-136.
10. Uyttendaele H, Marazzi G, Wu G, Yan Q, Sassoon D, Kitajewski J. Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene. Development 1996;122:2251-2259.
11. Lindsell CE, Shawber CJ, Boulter J, Weinmaster G. Jagged: a mammalian ligand that activates Notch1. Cell 1995;80:909-917.
12. Bettenhausen B, Hrabe de Angelis M, Simon D, Guenet JL, Gossler A. Transient and restricted expression during mouse embryo-genesis of Dll1, a murine gene closely related to Drosophila Delta. Development 1995;121:2407-2418.
13. Dunwoodie SL, Henrique D, Harrison SM, Beddington RS. Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development 1997;124:3065-3076.
14. Shawber C, Boulter J, Lindsell CE, Weinmaster G. Jagged2: a serrate-like gene expressed during rat embryogenesis. Dev Biol 1996;180:370-376.
15. Shutter JR et al. Dll4, a novel Notch ligand expressed in arterial endothelium. Genes Dev 2000;14:1313-1318.
16. Blaumueller CM, Qi H, Zagouras P, Artavanis-Tsakonas S. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 1997;90:281-291.
17. Logeat F, et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. Proc Natl Acad Sci USA 1998;95:8108-8112.
18. Weinmaster G. Notch signal transduction: a real rip and more. Curr Opin Genet Dev 2000;10:363-369.
19. Furukawa T, Kawaichi M, Matsunami N, Ryo H, Nishida Y, Honjo T. The Drosophila RBP-Jκ gene encodes the binding protein for the immunoglobulin Jκ recombination signal sequence. J Biol Chem 1991;266:23334-23340.
20. Irvine KD, Wieschaus E. Fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 1994;79:595-606.
21. Panin VM, Papayannopoulos V, Wilson R, Irvine KD. Fringe modulates Notch-ligand interactions. Nature 1997;387:908-912.
22. Panin VM, Irvine KD. Modulators of Notch signaling. Semin Cell Dev Biol 1998;9:609-617.
23. + hematopoietic precursors. Blood 1994;83:2057-2062.
24. Li L, et al. The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity 1998;8:43-55.
25. Milner LA, Bigas A. Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation. Blood 1999;93:2431-2448.
26. Lewis J. Neurogenic genes and vertebrate neurogenesis. Curr Opin Neurobiol 1996;6:3-10.
27. Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 1995;375:761-766.
28. Henrique D, et al. Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Curr Biol 1997;7:661-670.
29. Karanu FN, et al. The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells. J Exp Med 2000;192:1365-1372.
30. Milner LA, Bigas A, Kopan R, Brashem-Stein C, Bernstein ID, Martin DI. Inhibition of granulocytic differentiation by mNotch1. Proc Natl Acad Sci USA 1996;93:13014-13019.
31. Carlesso N, Aster JC, Sklar J, Scadden DT. Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics. Blood 1999;93:838-848.
32. Shelly LL, Fuchs C, Miele L. Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds. J Cell Biochem 1999;73:164-175.
33. Schroeder T, Just U. Notch signalling via RBP-Jκ promotes myeloid differentiation. EMBO J 2000;19:2558-2568.
34. Kawamata SC, Li K, Lavau C. Notch1 perturbation of hemopoiesis involves non-cell-autonomous modifications. J Immunol 2002;168:1738-1745.
35. Stier S, Cheng T, Dombkowski D, Carlesso N, Scadden DT. Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome. Blood 2002;99:2369-2378.
36. Pui JC, et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 1999;11:299-308.
37. + thymocytes by modulating TCR signal strength. Immunity 2001;14:253-264.
38. Radtke F, Ferrero I, Wilson A, Lees R, Aguet M, MacDonald HR. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. J Exp Med 2000;191:1085-1094.
39. Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661-672.
40. Radtke F, et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999;10:547-558.
41. Wilson A, Ferrero I, MacDonald HR, Radtke F. Cutting edge. an essential role for notch-1 in the development of both thymus-independent and -dependent T cells in the Gut. J Immunol 2000;165:5397-5400.
42. Wilson A, MacDonald HR, Radtke F. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J Exp Med 2001;194:1003-1012.
43. Yan XQ, et al. A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer. Blood 2001;98:3793-3999.
44. Jaleco AC, et al. Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. J Exp Med 2001;194:991-1002.
45. Fleming RJ, Gu Y, Hukriede NA. Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc. Development 1997;124:2973-2981.
46. Koch U, et al. Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1. Immunity 2001;15:225-236.
47. Xu T, Artavanis-Tsakonas S. Deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster. Genetics 1990;126:665-677.
48. Sestan N, Artavanis-Tsakonas S, Rakic P. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 1999;286:741-746.
49. Izon DJ, et al. Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing notch1. Immunity 2002;16:231-243.
50. Fehling HJ, Gilfillan S, Ceredig R. Alpha beta/gamma delta lineage commitment in the thymus of normal and genetically manipulated mice. Adv Immunol 1999;71:1-76.
51. + T cells from a common precursor. Semin Immunol 1997;9:171-179.
52. MacDonald HR, Wilson A. The role of the T-cell receptor (TCR) in αβ/γδ lineage commitment: clues from intracellular TCR staining. Immunol Rev 1998;165:87-94.
53. Robey E, Fowlkes BJ. The αβ versus γδ T-cell lineage choice. Curr Opin Immunol 1998;10:181-187.
54. Washburn T, et al. Notch activity influences the ab versus gd T cell lineage decision. Cell 1997;88:833-843.
55. Wolfer A, et al. Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development. Nature Immunol 2001;3:235-241.
56. Wolfer A, et al. Inactivation of Notch1 impairs VDJβ rearrangement and allows pre TCR independent survival of early αβ lineage thymocytes. Immunity 2002;16:869-879.
57. Kang J, Volkmann A, Raulet DH. Evidence that γδ versus αβ T cell fate determination is initiated independently of T cell receptor signaling. J Exp Med 2001;193:689-698.
58. Hernandez-Hoyos G, Sohn SJ, Rothenberg EV, Alberola-Ila J. Lck activity controls CD4/CD8 T cell lineage commitment. Immunity 2000;12:313-322.
59. Legname G, et al. Inducible expression of a p56Lck transgene reveals a central role for Lck in the differentiation of CD4 SP thymocytes. Immunity 2000;12:537-546.
60. Robey E, et al. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 1996;87:483-492.
61. Deftos ML, Bevan MJ. Notch signaling in T cell development. Curr Opin Immunol 2000;12:166-172.
62. + T-cell lineage fate. Nature 2000;404:506-510.
63. Felli MP, et al. Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol 1999;11:1017-1025.
64. Doerfler P. Shearman MS, Perlmutter RM. Presenilin-dependent γ-secretase activity modulates thymocyte development. Proc Natl Acad Sci USA 2001;98:9312-9317.
65. Hadland BK, et al. γ-secretase inhibitors repress thymocyte development. Proc Natl Acad Sci USA 2001;98:7487-7491.
66. Hoyne GF, et al. Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4 (+) T cells. Int Immunol 2000;12:177-185.
67. Hoyne GF, Dallman MJ, Lamb JR. Linked suppression in peripheral T cell tolerance to the house dust mite derived allergen Der p 1. Int Arch Allergy Immunol 1999;118:122-124.