The Notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse

Stem Cells

Volumn 19, Issue 6, 2001, Pages 543-552

  Walker, Liberty ^a   Carlson, Anne ^b   Tan Pertel, Hongying Tina ^b   Weinmaster, Gerry ^a,b   Gasson, Judith ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Delta1; Fetal; Hematopoiesis; Jagged1; Notch1; Notch2

Indexed keywords

ERYTHROPOIETIN; LIGAND; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL MATURATION; CONTROLLED STUDY; ERYTHROPOIESIS; GRANULOPOIESIS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STROMA CELL;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0035176397     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.19-6-543     Document Type: Article

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10. Jagged2: A serratelike gene expressed during rat embryogenesis
11. Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor
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13. Notchl is required for the coordinate segmentation of somites
14. A homolog of Drosophila Notch expressed during mammalian development
15. Notch2: A second mammalian Notch gene
16. Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation
17. The human homolog of rat Jagged 1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
18. Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells
19. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
20. Modulated expression of Notch1 during thymocyte development
21. TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
22. Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1
23. Notch-1 and Notch2 exhibit unique patterns of expression in human B-lineage cells
24. Notch signaling enhances survival and alters differentiation of 32D myeloblasts
25. Expression of Notch receptors, Notch ligands, and Fringe genes in hematopoiesis
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27. + hematopoietic precursors
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29. Constitutive activation of NF-κB and T-cell leukemia/lymphoma in Notch3 transgenic mice
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31. Protective effects of Notch1 on TCR-induced apoptosis
32. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
33. Notch activity influences the alpha beta versus gamma delta T cell lineage decision
34. Notch signalling via RBP-J promotes myeloid differentiation
35. Notch signaling reduces proliferation of myeloid progenitor cells by altering cell-cycle kinetics
36. The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro
37. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
38. Localization of ADAM10 and Notch receptors in bone
39. Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway
40. Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation
41. Cell-specific cyclic AMP-mediated induction of the PDGF receptor
42. Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development
43. Notchl-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics
44. Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
45. Suppression of erythroid but not megakaryocytic differentiation of human K562 erythroleukemic cells by Notch-1
46. A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
47. Stepwise specification of lymphocyte developmental lineages
48. Notch1 expression in early lymphopoiesis influences B versus T lineage determination
49. A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells
50. Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact
51. Development of hematopoietic stem cell activity in the mouse embryo
52. Definitive hematopoiesis is autonomously initiated by the AGM region
53. An early pre-liver intraembryonic source of CFU-S in the developing mouse
54. Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo
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56. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
57. Notch signaling is essential for vascular morphogenesis in mice
58. Apoptosis and hematopoiesis in murine fetal liver
59. Ultrastructural analysis of hepatic haematopoiesis in the foetal mouse
60. JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome
61. Hepatic Jaggedl expression studies
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