Making a vertebrate limb: New players enter from the wings

BioEssays

Volumn 23, Issue 10, 2001, Pages 865-868

  Martin, Gail ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 8; ONCOPROTEIN; WNT PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL; LIMB; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SIGNAL TRANSDUCTION; VERTEBRATE;

ANIMALS; EXTREMITIES; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; VERTEBRATES; WNT PROTEINS; ZEBRAFISH PROTEINS;

VERTEBRATA;

EID: 0034800356     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.1126     Document Type: Review

References (23)

1. WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo
2. Studies on a limbless mutant in the chick embryo
3. A quantitative analysis of the effect of excision of the AER from the chick limb bud
4. The roles of FGFs in me early development of vertebrate limbs
5. Fibroblast growth factors induce additional limb development from the flank of chick embryos
6. Protein modules and signalling networks
7. Signal transduction by fibroblast growth factor receptors
8. Fibroblast growth factors as multifunctional signaling factors
9. Fibroblast growth factors
10. Roles for FGF8 in the induction, initiation, and maintenance of chick limb development
11. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb
12. The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
13. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless
14. Fgf10 is essential for limb and lung formation
15. Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4
16. Fibrobast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation ICCp between FGF8 and FGF10 is essential for limb induction
17. Fgf8 signalling from me AER is essential for normal limb development
18. Fgf8 is required for outgrowth and patterning of the limbs
19. Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
20. Mechanisms of Wnt signaling in development
21. Beta-catenin: A key mediator of Wnt signaling
22. Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb
23. Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud