-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
0034471796
-
Molecular mechanisms of tumor angiogenesis and tumor progression
-
Cavallaro U, Christofori G. Molecular mechanisms of tumor angiogenesis and tumor progression. J Neurooncol 2000; 50: 63-70.
-
(2000)
J Neurooncol
, vol.50
, pp. 63-70
-
-
Cavallaro, U.1
Christofori, G.2
-
3
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. Mechanisms of angiogenesis. Nature 1997; 386: 671-4.
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
4
-
-
0034076189
-
Mechanisms of angiogenesis and arteriogenesis
-
Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6: 389-95.
-
(2000)
Nat Med
, vol.6
, pp. 389-395
-
-
Carmeliet, P.1
-
5
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002; 2: 727-39.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
6
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407: 249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
0033588842
-
New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
-
Holash J, Wiegand SJ, Yancopoulos GD. New model of tumor angiogenesis: Dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF. Oncogene 1999; 18: 5356-62.
-
(1999)
Oncogene
, vol.18
, pp. 5356-5362
-
-
Holash, J.1
Wiegand, S.J.2
Yancopoulos, G.D.3
-
8
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW, et al. Vascular-specific growth factors and blood vessel formation. Nature 2000; 407: 242-8.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
-
9
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes RO. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
10
-
-
0033374678
-
Cell adhesion: Old and new questions
-
Hynes RO. Cell adhesion: Old and new questions. Trends Cell Biol 1999; 9: M33-7.
-
(1999)
Trends Cell Biol
, vol.9
-
-
Hynes, R.O.1
-
13
-
-
0034715923
-
Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics
-
Sastry SK, Burridge K. Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics. Exp Cell Res 2000; 261: 25-36.
-
(2000)
Exp Cell Res
, vol.261
, pp. 25-36
-
-
Sastry, S.K.1
Burridge, K.2
-
15
-
-
0036222549
-
Sensing the environment: A historical perspective on integrin signal transduction
-
Miranti CK, Brugge JS. Sensing the environment: A historical perspective on integrin signal transduction. Nat Cell Biol 2002; 4: E83-90.
-
(2002)
Nat Cell Biol
, vol.4
-
-
Miranti, C.K.1
Brugge, J.S.2
-
16
-
-
0037043328
-
Tiny dancers: The integrin-growth factor nexus in angiogenic signaling
-
Smyth SS, Patterson C. Tiny dancers: The integrin-growth factor nexus in angiogenic signaling. J Cell Biol 2002; 158: 17-21.
-
(2002)
J Cell Biol
, vol.158
, pp. 17-21
-
-
Smyth, S.S.1
Patterson, C.2
-
17
-
-
0036039315
-
Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: Which side to target?
-
Rüegg C, Dormond O, Foletti A. Suppression of tumor angiogenesis through the inhibition of integrin function and signaling in endothelial cells: Which side to target? Endothelium 2002; 9: 151-60.
-
(2002)
Endothelium
, vol.9
, pp. 151-160
-
-
Rüegg, C.1
Dormond, O.2
Foletti, A.3
-
18
-
-
0035824920
-
Integrin and growth factor receptor crosstalk
-
Eliceiri B P. Integrin and growth factor receptor crosstalk. Circ Res 2001; 89: 1104-10.
-
(2001)
Circ Res
, vol.89
, pp. 1104-1110
-
-
Eliceiri, B.P.1
-
19
-
-
0038724539
-
Vascular integrins: Pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis
-
Rüegg C, Mariotti A. Vascular integrins: Pleiotropic adhesion and signaling molecules in vascular homeostasis and angiogenesis. Cell Mol Life Sci 1997; 78: 83-7.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1135-1157
-
-
Rüegg, C.1
Mariotti, A.2
-
20
-
-
0030809457
-
Targeted mutations in integrins and their ligands: Their implications for vascular biology
-
Hynes RO, Bader BL. Targeted mutations in integrins and their ligands: Their implications for vascular biology. Thromb Haemost 1997; 78: 83-7.
-
(1997)
Thromb Haemost
, vol.78
, pp. 83-87
-
-
Hynes, R.O.1
Bader, B.L.2
-
22
-
-
0034233562
-
In vivo functions of integrins: Lessons from null mutations in mice
-
Sheppard D. In vivo functions of integrins: Lessons from null mutations in mice. Matrix Biol 2000; 19: 203-9.
-
(2000)
Matrix Biol
, vol.19
, pp. 203-209
-
-
Sheppard, D.1
-
23
-
-
0035964805
-
Integrins in vascular development
-
Rupp PA, Little CD. Integrins in vascular development. Circ Res 2001; 89: 566-72.
-
(2001)
Circ Res
, vol.89
, pp. 566-572
-
-
Rupp, P.A.1
Little, C.D.2
-
24
-
-
0035800887
-
Functional consequences of integrin gene mutations in mice
-
Bouvard D, et al. Functional consequences of integrin gene mutations in mice. Circ Res 2001; 89: 211-23.
-
(2001)
Circ Res
, vol.89
, pp. 211-223
-
-
Bouvard, D.1
-
25
-
-
0027371908
-
Embryonic mesodermal defects in alpha 5 integrin-deficient mice
-
Yang JT, Rayburn H, Hynes RO. Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development 1993; 119: 1093-105.
-
(1993)
Development
, vol.119
, pp. 1093-1105
-
-
Yang, J.T.1
Rayburn, H.2
Hynes, R.O.3
-
26
-
-
0035983579
-
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies
-
Francis SE, Goh KL, Hodivala-Dilke K, et al. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol 2002; 22: 927-33.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 927-933
-
-
Francis, S.E.1
Goh, K.L.2
Hodivala-Dilke, K.3
-
27
-
-
0028955748
-
Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development
-
Yang JT, Rayburn H, Hynes RO. Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development 1995; 121: 549-60.
-
(1995)
Development
, vol.121
, pp. 549-560
-
-
Yang, J.T.1
Rayburn, H.2
Hynes, R.O.3
-
28
-
-
0032514841
-
Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins
-
Bader BL, Rayburn H, Crowley D, et al. Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell 1998; 95: 507-19.
-
(1998)
Cell
, vol.95
, pp. 507-519
-
-
Bader, B.L.1
Rayburn, H.2
Crowley, D.3
-
29
-
-
0036837873
-
Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins
-
McCarty JH, Monahan-Earley RA, Brown LF et al. Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins. Mol Cell Biol 2002; 22: 7667-77.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7667-7677
-
-
McCarty, J.H.1
Monahan-Earley, R.A.2
Brown, L.F.3
-
30
-
-
0033621890
-
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts
-
McHugh KP, Hodivala-Dilke K, Zheng MH et al. Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest 2000; 105: 433-40.
-
(2000)
J Clin Invest
, vol.105
, pp. 433-440
-
-
McHugh, K.P.1
Hodivala-Dilke, K.2
Zheng, M.H.3
-
31
-
-
0033982574
-
Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice
-
Huang X, Griffiths M, Wu J, et al. Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice. Mol Cell Biol 2000; 20: 755-9.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 755-759
-
-
Huang, X.1
Griffiths, M.2
Wu, J.3
-
32
-
-
0036152857
-
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins
-
Reynolds LE, Wyder L, Lively JC, et al. Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. Nat Med 2002; 8: 27-34.
-
(2002)
Nat Med
, vol.8
, pp. 27-34
-
-
Reynolds, L.E.1
Wyder, L.2
Lively, J.C.3
-
33
-
-
0034568429
-
Glanzmann thrombasthenia: Integrin alpha IIb beta 3 deficiency
-
Tomiyama Y. Glanzmann thrombasthenia: Integrin alpha IIb beta 3 deficiency. Int J Hematol 2000; 72: 448-54.
-
(2000)
Int J Hematol
, vol.72
, pp. 448-454
-
-
Tomiyama, Y.1
-
34
-
-
0032725055
-
Insights and questions arising from studies of a mouse model of Glanzmann thrombasthenia
-
Hynes RO, Hodivala-Dilke KM. Insights and questions arising from studies of a mouse model of Glanzmann thrombasthenia. Thromb Haemost 1999; 82: 481-5.
-
(1999)
Thromb Haemost
, vol.82
, pp. 481-485
-
-
Hynes, R.O.1
Hodivala-Dilke, K.M.2
-
35
-
-
0033948027
-
Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1
-
Huang XZ, Wu JF, Ferrando R, et al. Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1. Mol Cell Biol 2000; 20: 5208-15.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5208-5215
-
-
Huang, X.Z.1
Wu, J.F.2
Ferrando, R.3
-
36
-
-
18544386859
-
Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
-
Petrova TV, Makinen T, Makela TP, et al. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. Embo J 2002; 21: 4593-9.
-
(2002)
Embo J
, vol.21
, pp. 4593-4599
-
-
Petrova, T.V.1
Makinen, T.2
Makela, T.P.3
-
37
-
-
0029686918
-
Tumor angiogenesis and the role of vascular cell integrin alphavbeta3
-
Varner JA, Cheresh DA. Tumor angiogenesis and the role of vascular cell integrin alphavbeta3. Important Adv Oncol 1996; 69-87.
-
(1996)
Important Adv Oncol
, pp. 69-87
-
-
Varner, J.A.1
Cheresh, D.A.2
-
38
-
-
0028362876
-
Requirement of vascular integrin alpha v beta 3 for angiogenesis
-
Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 1994; 264: 569-71.
-
(1994)
Science
, vol.264
, pp. 569-571
-
-
Brooks, P.C.1
Clark, R.A.2
Cheresh, D.A.3
-
39
-
-
0030993245
-
Immunohistochemical analysis of integrin alpha vbeta3 expression on tumor-associated vessels of human carcinomas
-
Max R, Gerritsen RR, Nooijen PT, et al. Immunohistochemical analysis of integrin alpha vbeta3 expression on tumor-associated vessels of human carcinomas. Int J Cancer 1997; 71: 320-4.
-
(1997)
Int J Cancer
, vol.71
, pp. 320-324
-
-
Max, R.1
Gerritsen, R.R.2
Nooijen, P.T.3
-
40
-
-
0031862889
-
Detection of tumor angiogenesis in vivo by alpha V beta 3 - Targeted magnetic resonance imaging
-
Sipkins DA, Cheresh DA, Kazemi MR, et al. Detection of tumor angiogenesis in vivo by alpha V beta 3 - Targeted magnetic resonance imaging. Nat Med 1998; 4: 623-6.
-
(1998)
Nat Med
, vol.4
, pp. 623-626
-
-
Sipkins, D.A.1
Cheresh, D.A.2
Kazemi, M.R.3
-
41
-
-
0005306564
-
Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor
-
Cheresh DA. Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. Proc Natl Acad Sci U S A 1987; 84: 6471-5.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 6471-6475
-
-
Cheresh, D.A.1
-
42
-
-
0033549864
-
N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists
-
Dechantsreiter MA, Planker E, Matha B, et al. N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists. J Med Chem 1999; 42: 3033-40.
-
(1999)
J Med Chem
, vol.42
, pp. 3033-3040
-
-
Dechantsreiter, M.A.1
Planker, E.2
Matha, B.3
-
43
-
-
0029610677
-
Definition of two angiogenic pathways by distinct alpha v integrins
-
Friedlander M, Brooks PC, Shaffer RW, et al. Definition of two angiogenic pathways by distinct alpha v integrins. Science 1995; 270: 1500-2.
-
(1995)
Science
, vol.270
, pp. 1500-1502
-
-
Friedlander, M.1
Brooks, P.C.2
Shaffer, R.W.3
-
44
-
-
0029925079
-
Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
-
Hammes HP, Brownlee M, Jonczyk A, et al. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nat Med 1996; 2: 529-33.
-
(1996)
Nat Med
, vol.2
, pp. 529-533
-
-
Hammes, H.P.1
Brownlee, M.2
Jonczyk, A.3
-
45
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks PC, Montgomery AM, Rosenfeld M, et al. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994; 79: 1157-64.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
-
46
-
-
0028972105
-
Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
-
Brooks PC, Stromblad S, Klemke R, et al. Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. J Clin Invest 1995; 96: 1815-22.
-
(1995)
J Clin Invest
, vol.96
, pp. 1815-1822
-
-
Brooks, P.C.1
Stromblad, S.2
Klemke, R.3
-
47
-
-
0033558087
-
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2
-
Soldi R, Mitola S, Strasly M, et al. Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. Embo J 1999; 18: 882-92.
-
(1999)
Embo J
, vol.18
, pp. 882-892
-
-
Soldi, R.1
Mitola, S.2
Strasly, M.3
-
48
-
-
0032498640
-
Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
-
Eliceiri BP, et al. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J. Cell Biol 1998; 140: 1255-63.
-
(1998)
J. Cell Biol
, vol.140
, pp. 1255-1263
-
-
Eliceiri, B.P.1
-
49
-
-
15844420283
-
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
-
Brooks PC, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996; 85: 683-93.
-
(1996)
Cell
, vol.85
, pp. 683-693
-
-
Brooks, P.C.1
-
50
-
-
0033636606
-
A mechanism for modulation of cellular responses to VEGF: Activation of the integrins
-
Byzova TV, Goldman CK, Pampori N, et al. A mechanism for modulation of cellular responses to VEGF: Activation of the integrins. Mol Cell 2000; 6: 851-60.
-
(2000)
Mol Cell
, vol.6
, pp. 851-860
-
-
Byzova, T.V.1
Goldman, C.K.2
Pampori, N.3
-
51
-
-
0031596991
-
NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival
-
Scatena M, Almeida M, Chaisson ML, et al. NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. J Cell Biol 1998; 141: 1083-93.
-
(1998)
J Cell Biol
, vol.141
, pp. 1083-1093
-
-
Scatena, M.1
Almeida, M.2
Chaisson, M.L.3
-
52
-
-
0030038229
-
Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
-
Stromblad S, Becker JC, Yebra M, et al. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. J Clin Invest 1996; 98: 426-33.
-
(1996)
J Clin Invest
, vol.98
, pp. 426-433
-
-
Stromblad, S.1
Becker, J.C.2
Yebra, M.3
-
53
-
-
0035851912
-
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
-
Stupack DG, Puente XS, Boutsaboualoy S, et al. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol 2001; 155: 459-70.
-
(2001)
J Cell Biol
, vol.155
, pp. 459-470
-
-
Stupack, D.G.1
Puente, X.S.2
Boutsaboualoy, S.3
-
54
-
-
0036734093
-
A reevaluation of integrins as regulators of angiogenesis
-
Hynes RO. A reevaluation of integrins as regulators of angiogenesis. Nat Med 2002; 8: 918-21.
-
(2002)
Nat Med
, vol.8
, pp. 918-921
-
-
Hynes, R.O.1
-
55
-
-
0032969073
-
Endothelial cell integrin alpha5beta1 expression in modulated by cytokines and during migration in vitro
-
Collo G, Pepper MS. Endothelial cell integrin alpha5beta1 expression in modulated by cytokines and during migration in vitro. Journal of Cell Science 1999; 112: 569-78.
-
(1999)
Journal of Cell Science
, vol.112
, pp. 569-578
-
-
Collo, G.1
Pepper, M.S.2
-
56
-
-
0035394235
-
Reduced blood vessel formation and tumor growth in alpha5-integrin-negative teratocarcinomas and embryoid bodies
-
Taverna D, Hynes RO. Reduced blood vessel formation and tumor growth in alpha5-integrin-negative teratocarcinomas and embryoid bodies. Cancer Res 2001; 61: 5255-61.
-
(2001)
Cancer Res
, vol.61
, pp. 5255-5261
-
-
Taverna, D.1
Hynes, R.O.2
-
57
-
-
0036792466
-
Inhibition of endothelial cell survival and angiogenesis by protein kinase A
-
Kim S, Bakre M, Yin H, Varner JA. Inhibition of endothelial cell survival and angiogenesis by protein kinase A. J Clin Invest 2002; 110: 933-41.
-
(2002)
J Clin Invest
, vol.110
, pp. 933-941
-
-
Kim, S.1
Bakre, M.2
Yin, H.3
Varner, J.A.4
-
58
-
-
0034721888
-
Regulation of integrin alpha vbeta 3-mediated endothelial cell migration and angiogenesis by integrin alpha 5beta 1 and protein kinase A
-
Kim S, Harris M, Varner JA. Regulation of integrin alpha vbeta 3-mediated endothelial cell migration and angiogenesis by integrin alpha 5beta 1 and protein kinase A J Biol Chem 2000; 275: 33920-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 33920-33928
-
-
Kim, S.1
Harris, M.2
Varner, J.A.3
-
59
-
-
0029120428
-
A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins
-
Pasqualini R, Koivunen E, Ruoslahti E. A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins. J Cell Biol 1995; 130: 1189-96.
-
(1995)
J Cell Biol
, vol.130
, pp. 1189-1196
-
-
Pasqualini, R.1
Koivunen, E.2
Ruoslahti, E.3
-
60
-
-
0037457423
-
Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice
-
Stoeltzing O, Liu W, Reinmuth N, et al. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer 2003; 104: 496-503.
-
(2003)
Int J Cancer
, vol.104
, pp. 496-503
-
-
Stoeltzing, O.1
Liu, W.2
Reinmuth, N.3
-
62
-
-
0036142782
-
The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis
-
Senger DR, Perruzzi CA, Streit M, et al. The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 2002; 160: 195-204.
-
(2002)
Am J Pathol
, vol.160
, pp. 195-204
-
-
Senger, D.R.1
Perruzzi, C.A.2
Streit, M.3
-
63
-
-
0036828258
-
Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium
-
Funahashi Y, Sugi NH, Semba T, et al. Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. Cancer Res 2002; 62: 6116-23.
-
(2002)
Cancer Res
, vol.62
, pp. 6116-6123
-
-
Funahashi, Y.1
Sugi, N.H.2
Semba, T.3
-
64
-
-
0034007381
-
Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization
-
Pozzi A, Moberg PE, Miles LA, et al. Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization. Proc Natl Acad Sci USA 2000; 97: 2202-7.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2202-2207
-
-
Pozzi, A.1
Moberg, P.E.2
Miles, L.A.3
-
65
-
-
0032572410
-
Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo
-
Pozzi A, Wary KK, Giancotti FG, et al. Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo. J Cell Biol 1998; 142: 587-94.
-
(1998)
J Cell Biol
, vol.142
, pp. 587-594
-
-
Pozzi, A.1
Wary, K.K.2
Giancotti, F.G.3
-
66
-
-
0033035808
-
Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis
-
Gardner H, Broberg A, Pozzi A, et al. Absence of integrin alpha1beta1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis. J Cell Sci 1999; 112: 263-72.
-
(1999)
J Cell Sci
, vol.112
, pp. 263-272
-
-
Gardner, H.1
Broberg, A.2
Pozzi, A.3
-
67
-
-
0037192771
-
Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen
-
Holtkotter O, Nieswandt B, Smyth N, et al. Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem 2002; 277: 10789-94.
-
(2002)
J Biol Chem
, vol.277
, pp. 10789-10794
-
-
Holtkotter, O.1
Nieswandt, B.2
Smyth, N.3
-
68
-
-
0036314793
-
The alpha(2) integrin subunit-deficient mouse: A multifaceted phenotype including defects of branching morphogenesis and hemostasis
-
Chen J, Diacovo TG, Grenache DG, et al. The alpha(2) integrin subunit-deficient mouse: A multifaceted phenotype including defects of branching morphogenesis and hemostasis. Am J Pathol 2002; 161: 337-44.
-
(2002)
Am J Pathol
, vol.161
, pp. 337-344
-
-
Chen, J.1
Diacovo, T.G.2
Grenache, D.G.3
-
69
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer, and development
-
Williams CS, Mann M, DuBois RN. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999; 18: 7908-16.
-
(1999)
Oncogene
, vol.18
, pp. 7908-7916
-
-
Williams, C.S.1
Mann, M.2
DuBois, R.N.3
-
70
-
-
0027197062
-
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
-
Giardiello FM, Hamilton SR, Krush AJ, et al. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 1993; 328: 1313-6.
-
(1993)
N Engl J Med
, vol.328
, pp. 1313-1316
-
-
Giardiello, F.M.1
Hamilton, S.R.2
Krush, A.J.3
-
71
-
-
0034685192
-
COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease
-
Willoughby DA, Moore AR, Colville-Nash PR. COX-1, COX-2, and COX-3 and the future treatment of chronic inflammatory disease. Lancet 2000; 355: 646-8.
-
(2000)
Lancet
, vol.355
, pp. 646-648
-
-
Willoughby, D.A.1
Moore, A.R.2
Colville-Nash, P.R.3
-
72
-
-
0037108979
-
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
-
Chandrasekharan NV, Dai H, Roos KL, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Proc Natl Acad Sci USA 2002; 99: 13926-31.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13926-13931
-
-
Chandrasekharan, N.V.1
Dai, H.2
Roos, K.L.3
-
73
-
-
0031689543
-
Cyclooxygenase in biology and disease
-
Dubois RN, Abramson SB, Crofford L, et al. Cyclooxygenase in biology and disease. Faseb J 1998; 12: 1063-73.
-
(1998)
Faseb J
, vol.12
, pp. 1063-1073
-
-
Dubois, R.N.1
Abramson, S.B.2
Crofford, L.3
-
74
-
-
0026716651
-
Regulation of mesangial cell cyclooxygenase synthesis by cytokines and glucocorticoids
-
Coyne DW, Nickols M, Bertrand W, et al. Regulation of mesangial cell cyclooxygenase synthesis by cytokines and glucocorticoids. Am J Physiol 1992; 263: F97-102.
-
(1992)
Am J Physiol
, vol.263
-
-
Coyne, D.W.1
Nickols, M.2
Bertrand, W.3
-
75
-
-
0013181383
-
Identification of a phorbol ester-repressible v-src-inducible gene
-
Simmons DL, Levy DB, Yannoni Y, et al. Identification of a phorbol ester-repressible v-src-inducible gene. Proc Natl Acad Sci U S A 1989; 86: 1178-82.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 1178-1182
-
-
Simmons, D.L.1
Levy, D.B.2
Yannoni, Y.3
-
76
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart CE, Coffey RJ, Radhika A, et al. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994; 107: 1183-8.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
-
77
-
-
0030606299
-
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Oshima M, Dinchuk JE, Kargman SL, et al. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996; 87: 803-9.
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
-
78
-
-
0037126069
-
Transgenic cyclooxgenase-2 overexpression sensitizes mouse skin for carcinogenesis
-
Muller-Decker K, Neufang G, Berger I, et al. Transgenic cyclooxgenase-2 overexpression sensitizes mouse skin for carcinogenesis. Proc Natl Acad Sci U S A 2002; 99: 12483-8.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12483-12488
-
-
Muller-Decker, K.1
Neufang, G.2
Berger, I.3
-
79
-
-
0035947709
-
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
-
Liu CH, Chang SH, Narko K, et al. Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 2001; 276: 18563-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 18563-18569
-
-
Liu, C.H.1
Chang, S.H.2
Narko, K.3
-
80
-
-
0034089566
-
Host cyclooxygenase-2 modulates carcinoma growth
-
Williams CS, Tsujii M, Reese J, et al. Host cyclooxygenase-2 modulates carcinoma growth. J Clin Invest 2000; 105: 1589-94.
-
(2000)
J Clin Invest
, vol.105
, pp. 1589-1594
-
-
Williams, C.S.1
Tsujii, M.2
Reese, J.3
-
81
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G, Lynch PM, Phillips RK, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000; 342: 1946-52.
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.3
-
82
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
Masferrer JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000; 60: 1306-11.
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
-
83
-
-
0036468287
-
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
-
Leahy KM, Ornberg RL, Wang Y, et al. Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 2002; 62: 625-31.
-
(2002)
Cancer Res
, vol.62
, pp. 625-631
-
-
Leahy, K.M.1
Ornberg, R.L.2
Wang, Y.3
-
84
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii M, Kawano S, Tsuji S, et al. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998; 93: 705-16.
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
-
85
-
-
0032750920
-
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
-
Jones MK, Wang H, Peskar BM, et al. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 1999; 5: 1418-23.
-
(1999)
Nat Med
, vol.5
, pp. 1418-1423
-
-
Jones, M.K.1
Wang, H.2
Peskar, B.M.3
-
86
-
-
0034791297
-
NSAIDs inhibit alphaVbeta3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
-
Dormond O, Foletti A, Paroz C, et al. NSAIDs inhibit alphaVbeta3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat Med 2001; 7: 1041-7.
-
(2001)
Nat Med
, vol.7
, pp. 1041-1047
-
-
Dormond, O.1
Foletti, A.2
Paroz, C.3
-
87
-
-
0037195421
-
Prostaglandin E2 promotes integrin aVb3-dependent endothelial cell adhesion, Rac-activation and spreading through cAMP/PKA signaling
-
Dormond O, Bezzi M, Mariotti A, et al. Prostaglandin E2 promotes integrin aVb3-dependent endothelial cell adhesion, Rac-activation and spreading through cAMP/PKA signaling. J Biol Chem 2002; 277: 45838-46.
-
(2002)
J Biol Chem
, vol.277
, pp. 45838-45846
-
-
Dormond, O.1
Bezzi, M.2
Mariotti, A.3
-
88
-
-
0035672899
-
Rac regulates vascular endothelial growth factor stimulated motility
-
Soga N, Connolly JO, Chellaiah M, et al. Rac regulates vascular endothelial growth factor stimulated motility. Cell Comm Adhes 2001; 8: 1-13.
-
(2001)
Cell Comm Adhes
, vol.8
, pp. 1-13
-
-
Soga, N.1
Connolly, J.O.2
Chellaiah, M.3
-
89
-
-
0037023648
-
A dominant-negative p65 PAK peptide inhibits angiogenesis
-
Kiosses WB, Hood J, Yang S, et al. A dominant-negative p65 PAK peptide inhibits angiogenesis. Circ Res 2002; 90: 697-702.
-
(2002)
Circ Res
, vol.90
, pp. 697-702
-
-
Kiosses, W.B.1
Hood, J.2
Yang, S.3
-
90
-
-
0026595961
-
Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion
-
Shimizu Y, Van Seventer GA, Ennis E, et al. Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion. J Exp Med 1992; 175: 577-82.
-
(1992)
J Exp Med
, vol.175
, pp. 577-582
-
-
Shimizu, Y.1
Van Seventer, G.A.2
Ennis, E.3
-
91
-
-
0026014052
-
Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets
-
Van Willigen G, Akkerman JW. Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets. Biochem J 1991; 273: 115-20.
-
(1991)
Biochem J
, vol.273
, pp. 115-120
-
-
Van Willigen, G.1
Akkerman, J.W.2
-
92
-
-
0026708982
-
Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. II. Interaction between phorbol ester- and cAMP-sensitive pathways
-
Haverstick DM, Gray LS. Lymphocyte adhesion mediated by lymphocyte function-associated antigen-1. II. Interaction between phorbol ester- and cAMP-sensitive pathways. J Immunol 1992; 149: 397-402.
-
(1992)
J Immunol
, vol.149
, pp. 397-402
-
-
Haverstick, D.M.1
Gray, L.S.2
-
93
-
-
0028807730
-
Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes
-
Halvorson MJ, Coligan JE. Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes. J Immunol 1995; 155: 4567-74.
-
(1995)
J Immunol
, vol.155
, pp. 4567-4574
-
-
Halvorson, M.J.1
Coligan, J.E.2
-
94
-
-
0025037387
-
Endothelial cell motility, integrin receptor clustering, and microfilament organization are inhibited by agents that increase intracellular cAMP
-
Lampugnani MG, Giorgi M, Gaboli M, et al. Endothelial cell motility, integrin receptor clustering, and microfilament organization are inhibited by agents that increase intracellular cAMP. Lab Invest 1990; 63: 521-31.
-
(1990)
Lab Invest
, vol.63
, pp. 521-531
-
-
Lampugnani, M.G.1
Giorgi, M.2
Gaboli, M.3
-
95
-
-
0030040750
-
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
-
Lang P, Gesbert F, Delespine-Carmagnat M, et al. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. Embo J 1996; 15: 510-9.
-
(1996)
Embo J
, vol.15
, pp. 510-519
-
-
Lang, P.1
Gesbert, F.2
Delespine-Carmagnat, M.3
-
96
-
-
0036734144
-
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor
-
Bakre MM, Zhu Y, Yin H, et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med 2002; 8: 995-1003.
-
(2002)
Nat Med
, vol.8
, pp. 995-1003
-
-
Bakre, M.M.1
Zhu, Y.2
Yin, H.3
-
97
-
-
0031587987
-
Dual action of cAMP-dependent protein kinase on granulocyte movement
-
Ydrenius L, Molony L, Ng-Sikorski J, et al. Dual action of cAMP-dependent protein kinase on granulocyte movement. Biochem Biophys Res Commun 1997; 235: 445-50.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 445-450
-
-
Ydrenius, L.1
Molony, L.2
Ng-Sikorski, J.3
-
98
-
-
0032405901
-
Meloxicam inhibits the growth of colorectal cancer cells
-
Goldman AP, Williams CS, Sheng H, et al. Meloxicam inhibits the growth of colorectal cancer cells. Carcinogenesis 1998; 19: 2195-9.
-
(1998)
Carcinogenesis
, vol.19
, pp. 2195-2199
-
-
Goldman, A.P.1
Williams, C.S.2
Sheng, H.3
-
99
-
-
0031721083
-
Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice
-
Fukutake M, Nakatsugi S, Isoi T, et al. Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice. Carcinogenesis 1998; 19: 1939-42.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1939-1942
-
-
Fukutake, M.1
Nakatsugi, S.2
Isoi, T.3
-
100
-
-
0033567459
-
Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis
-
Daniel TO, Liu H, Morrow JD, et al. Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis. Cancer Res 1999; 59: 4574-7.
-
(1999)
Cancer Res
, vol.59
, pp. 4574-4577
-
-
Daniel, T.O.1
Liu, H.2
Morrow, J.D.3
-
101
-
-
0034162780
-
Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor
-
Kishi K, Petersen S, Petersen C, et al. Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor. Cancer Res 2000; 60: 1326-31.
-
(2000)
Cancer Res
, vol.60
, pp. 1326-1331
-
-
Kishi, K.1
Petersen, S.2
Petersen, C.3
-
102
-
-
0034029780
-
Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants
-
Majima M, Hayashi I, Muramatsu M, et al. Cyclo-oxygenase-2 enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge implants. Br J Pharmacol 2000; 130: 641-9.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 641-649
-
-
Majima, M.1
Hayashi, I.2
Muramatsu, M.3
-
103
-
-
0033575760
-
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts
-
Zhang X, Morham SG, Langenbach R, et al. Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts. J Exp Med 1999; 190: 451-59.
-
(1999)
J Exp Med
, vol.190
, pp. 451-459
-
-
Zhang, X.1
Morham, S.G.2
Langenbach, R.3
-
104
-
-
0035650943
-
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib
-
Grosch S, Tegeder I, Niederberger E, et al. COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB J 2001; 15: 2742-4.
-
(2001)
FASEB J
, vol.15
, pp. 2742-2744
-
-
Grosch, S.1
Tegeder, I.2
Niederberger, E.3
-
105
-
-
0036254638
-
Antiangiogenic and chemopreventive activities of celecoxib in oral carcinoma cell
-
Wang Z, Fuentes CF, Shapshay SM. Antiangiogenic and chemopreventive activities of celecoxib in oral carcinoma cell. Laryngoscope 2002; 112: 839-43.
-
(2002)
Laryngoscope
, vol.112
, pp. 839-843
-
-
Wang, Z.1
Fuentes, C.F.2
Shapshay, S.M.3
-
106
-
-
0037089506
-
Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer
-
Kundu N, Fulton AM. Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer. Cancer Res 2002; 62: 2343-6.
-
(2002)
Cancer Res
, vol.62
, pp. 2343-2346
-
-
Kundu, N.1
Fulton, A.M.2
-
107
-
-
0036837835
-
Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle
-
Kundu N, Smyth MJ, Samsel L, et al. Cyclooxygenase inhibitors block cell growth, increase ceramide and inhibit cell cycle. Breast Cancer Res Tr 2002; 76: 57-64.
-
(2002)
Breast Cancer Res Tr
, vol.76
, pp. 57-64
-
-
Kundu, N.1
Smyth, M.J.2
Samsel, L.3
-
108
-
-
0037112442
-
Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors
-
Zweifel BS, Davis TW, Ornberg RL, et al. Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors. Cancer Res 2002; 62: 6706-11.
-
(2002)
Cancer Res
, vol.62
, pp. 6706-6711
-
-
Zweifel, B.S.1
Davis, T.W.2
Ornberg, R.L.3
-
109
-
-
0030602860
-
Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway
-
Hanif R, Pittas A, Feng Y, et al. Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. Biochem Pharmacol 1996; 52: 237-45.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 237-245
-
-
Hanif, R.1
Pittas, A.2
Feng, Y.3
-
110
-
-
0033859744
-
Blockade of cyclooxygenase-2 inhibits proliferation and induces apoptosis in human pancreatic cancer cells
-
Ding XZ, Tong WG, Adrian TE. Blockade of cyclooxygenase-2 inhibits proliferation and induces apoptosis in human pancreatic cancer cells. Anticancer Res 2000; 20: 2625-31.
-
(2000)
Anticancer Res
, vol.20
, pp. 2625-2631
-
-
Ding, X.Z.1
Tong, W.G.2
Adrian, T.E.3
-
111
-
-
0034660889
-
Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): In vitro antiproliferative effects of a COX-2 inhibitor
-
Marrogi A, Pass HI, Khan M, et al. Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): In vitro antiproliferative effects of a COX-2 inhibitor. Cancer Res 2000; 60: 3696-700.
-
(2000)
Cancer Res
, vol.60
, pp. 3696-3700
-
-
Marrogi, A.1
Pass, H.I.2
Khan, M.3
-
112
-
-
0030947525
-
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2
-
Sheng H, Shao J, Kirkland SC, et al.. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997; 99: 2254-9.
-
(1997)
J Clin Invest
, vol.99
, pp. 2254-2259
-
-
Sheng, H.1
Shao, J.2
Kirkland, S.C.3
-
113
-
-
0034646688
-
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2
-
Hsu AL, Ching TT, Wang DS, et al.. The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. J Biol Chem 2000; 275: 11397-403.
-
(2000)
J Biol Chem
, vol.275
, pp. 11397-11403
-
-
Hsu, A.L.1
Ching, T.T.2
Wang, D.S.3
-
114
-
-
0035879809
-
Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells
-
Li M, Wu X, Xu XC. Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. Int J Cancer 2001; 93: 218-23.
-
(2001)
Int J Cancer
, vol.93
, pp. 218-223
-
-
Li, M.1
Wu, X.2
Xu, X.C.3
-
115
-
-
0034665122
-
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis
-
Jacoby RF, Seibert K, Cole CE, et al.. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res 2000; 60: 5040-4.
-
(2000)
Cancer Res
, vol.60
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
Cole, C.E.3
-
116
-
-
0035866401
-
Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
-
Oshima M, Murai N, Kargman S, et al.. Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor. Cancer Res 2001; 61: 1733-40.
-
(2001)
Cancer Res
, vol.61
, pp. 1733-1740
-
-
Oshima, M.1
Murai, N.2
Kargman, S.3
-
117
-
-
0032006784
-
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
-
Kawamori T, Rao CV, Seibert K, et al.. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 1998; 58: 409-12.
-
(1998)
Cancer Res
, vol.58
, pp. 409-412
-
-
Kawamori, T.1
Rao, C.V.2
Seibert, K.3
-
118
-
-
0034650771
-
Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis
-
Reddy BS, Hirose Y, Lubet R, et al.. Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res 2000; 60: 293-7.
-
(2000)
Cancer Res
, vol.60
, pp. 293-297
-
-
Reddy, B.S.1
Hirose, Y.2
Lubet, R.3
-
119
-
-
0036792206
-
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer
-
Howe LR, Subbaramaiah K, Patel J, et al.. Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer. Cancer Res 2002; 62: 5405-7.
-
(2002)
Cancer Res
, vol.62
, pp. 5405-5407
-
-
Howe, L.R.1
Subbaramaiah, K.2
Patel, J.3
-
120
-
-
0035571588
-
Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis
-
Abou-Issa HM, Alshafie GA, Seibert K, et al. Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis. Anticancer Res 2001; 21: 3425-32.
-
(2001)
Anticancer Res
, vol.21
, pp. 3425-3432
-
-
Abou-Issa, H.M.1
Alshafie, G.A.2
Seibert, K.3
-
121
-
-
0034320268
-
Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model
-
Alshafie GA, Abou-Issa HM, Seibert K, et al.. Chemotherapeutic evaluation of Celecoxib, a cyclooxygenase-2 inhibitor, in a rat mammary tumor model. Oncol Rep 2000; 7: 1377-81.
-
(2000)
Oncol Rep
, vol.7
, pp. 1377-1381
-
-
Alshafie, G.A.1
Abou-Issa, H.M.2
Seibert, K.3
-
122
-
-
0034667354
-
Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats
-
Grubbs CJ, Lubet RA, Koki AT, et al.. Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats. Cancer Res 2000; 60: 5599-602.
-
(2000)
Cancer Res
, vol.60
, pp. 5599-5602
-
-
Grubbs, C.J.1
Lubet, R.A.2
Koki, A.T.3
-
123
-
-
0032929712
-
Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane
-
Yoshimi N, Shimizu M, Matsunaga K, et al.. Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane. Jpn J Cancer Res 1999; 90: 406-12.
-
(1999)
Jpn J Cancer Res
, vol.90
, pp. 406-412
-
-
Yoshimi, N.1
Shimizu, M.2
Matsunaga, K.3
-
124
-
-
0032403140
-
Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398
-
Rioux N, Castonguay A. Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398. Cancer Res 1998; 58: 5354-60.
-
(1998)
Cancer Res
, vol.58
, pp. 5354-5360
-
-
Rioux, N.1
Castonguay, A.2
-
125
-
-
0034326837
-
Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models
-
Williams CS, Watson AJ, Sheng H, et al.. Celecoxib prevents tumor growth in vivo without toxicity to normal gut: Lack of correlation between in vitro and in vivo models. Cancer Res 2000; 60: 6045-51.
-
(2000)
Cancer Res
, vol.60
, pp. 6045-6051
-
-
Williams, C.S.1
Watson, A.J.2
Sheng, H.3
-
126
-
-
0037311125
-
Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice
-
Yao M, Kargman S, Lam EC, et al.. Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. Cancer Res 2003; 63: 586-92.
-
(2003)
Cancer Res
, vol.63
, pp. 586-592
-
-
Yao, M.1
Kargman, S.2
Lam, E.C.3
-
127
-
-
15944388899
-
Selective cyclooxygenase-2 inhibitor rofecoxib (Vioxx) induces expression of cell cycle arrest genes and slows tumor growth in human pancreatic cancer
-
discussion 844
-
Tseng WW, Deganutti A, Chen MN, et al.. Selective cyclooxygenase-2 inhibitor rofecoxib (Vioxx) induces expression of cell cycle arrest genes and slows tumor growth in human pancreatic cancer. J Gastroint Surg 2002; 6: 838-43; discussion 844.
-
(2002)
J Gastroint Surg
, vol.6
, pp. 838-843
-
-
Tseng, W.W.1
Deganutti, A.2
Chen, M.N.3
-
128
-
-
0033391630
-
Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo
-
Sawaoka H, Tsuji S, Tsujii M, et al.. Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo. Lab Invest 1999; 79: 1469-77.
-
(1999)
Lab Invest
, vol.79
, pp. 1469-1477
-
-
Sawaoka, H.1
Tsuji, S.2
Tsujii, M.3
-
129
-
-
0036213316
-
Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane
-
Kishimoto Y, Yashima K, Morisawa T, et al.. Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane. J Gastroenterol 2002; 37: 186-93.
-
(2002)
J Gastroenterol
, vol.37
, pp. 186-193
-
-
Kishimoto, Y.1
Yashima, K.2
Morisawa, T.3
-
130
-
-
0001501848
-
Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo
-
Liu X H, Kirschenbaum A, Yao S, et al.. Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo. J Urol 2000; 164: 820-5.
-
(2000)
J Urol
, vol.164
, pp. 820-825
-
-
Liu, X.H.1
Kirschenbaum, A.2
Yao, S.3
-
131
-
-
0031799475
-
Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice
-
Sawaoka H, Kawano S, Tsuji S, et al.. Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice. Am J Physiol 1998; 274: G1061-7.
-
(1998)
Am J Physiol
, vol.274
-
-
Sawaoka, H.1
Kawano, S.2
Tsuji, S.3
-
132
-
-
0035882534
-
Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis
-
Rozic JG, Chakraborty C, Lala PK. Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis. Int J Cancer 2001; 93: 497-506.
-
(2001)
Int J Cancer
, vol.93
, pp. 497-506
-
-
Rozic, J.G.1
Chakraborty, C.2
Lala, P.K.3
-
133
-
-
0034769855
-
A cyclooxygenase-2 inhibitor (SC-58125) blocks growth of established human colon cancer xenografts
-
Williams CS, Sheng H, Brockman JA, et al.. A cyclooxygenase-2 inhibitor (SC-58125) blocks growth of established human colon cancer xenografts. Neoplasia 2001; 3: 428-36.
-
(2001)
Neoplasia
, vol.3
, pp. 428-436
-
-
Williams, C.S.1
Sheng, H.2
Brockman, J.A.3
-
134
-
-
0037108880
-
Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11
-
Trifan OC, Durham WF, Salazar VS, et al.. Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11. Cancer Res 2002; 62: 5778-84.
-
(2002)
Cancer Res
, vol.62
, pp. 5778-5784
-
-
Trifan, O.C.1
Durham, W.F.2
Salazar, V.S.3
|