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Volumn 8, Issue 9, 2002, Pages 995-1003

Parathyroid hormone-related peptide is a naturally occurring protein kinase A-dependent angiogenesis inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATASE; PARATHYROID HORMONE RELATED PROTEIN; RAC PROTEIN;

EID: 0036734144     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm753     Document Type: Article
Times cited : (94)

References (45)
  • 2
    • 0030635917 scopus 로고    scopus 로고
    • The role of vascular cell integrin αvβ3 and αvβ5 in angiogenesis
    • (1997) Exs. , vol.79 , pp. 361-390
    • Varner, J.A.1
  • 3
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • (1995) Nature Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 4
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1
  • 6
    • 0035805614 scopus 로고    scopus 로고
    • Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin
    • (2001) J. Biol. Chem. , vol.276 , pp. 15240-15248
    • Maeshima, Y.1
  • 10
    • 0028057743 scopus 로고
    • Lethal skeletal dysplasia from targeted deletion of the parathyroid hormone-related peptide gene
    • (1994) Genes. Dev. , vol.8 , pp. 277-289
    • Karaplis, A.C.1
  • 12
    • 0032717355 scopus 로고    scopus 로고
    • Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development
    • (1999) J. Clin. Invest. , vol.104 , pp. 399-407
    • Lanske, B.1
  • 13
    • 0026598246 scopus 로고
    • Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone related peptide from rat osteoblasts-like cells: A single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2732-2736
    • Abou-Samra, A.B.1
  • 14
    • 0035896569 scopus 로고    scopus 로고
    • Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor: Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation
    • (2001) J. Biol. Chem. , vol.276 , pp. 7741-7753
    • Hoare, S.1    Gardella, T.2    Usdin, T.B.3
  • 15
    • 0028232758 scopus 로고
    • Changes in parathyroid hormone receptors during chondrocyte cytodifferentiation
    • (1994) J. Biol. Chem. , vol.269 , pp. 17245-17251
    • Iwamoto, M.1
  • 16
    • 0033022243 scopus 로고    scopus 로고
    • Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility
    • (1999) Endocrinology , vol.140 , pp. 1815-1825
    • Maeda, S.1
  • 19
    • 0031851401 scopus 로고    scopus 로고
    • Amino-terminal fragment (1-34) of parathyroid hormone-related protein inhibits migration and proliferation of cultures vascular smooth muscle cells
    • (1998) Atherosclerosis , vol.136 , pp. 59-66
    • Ishikawa, M.1
  • 20
    • 0027292853 scopus 로고
    • Cloned, stably expressed parathyroid hormone (PTH)/PTH-related peptide receptors activate multiple messenger signals and biological responses in LLC-PK 1 kidney cells
    • (1993) Endocrinology , vol.132 , pp. 2090-2098
    • Bringhurst, F.R.1
  • 21
    • 10144241022 scopus 로고    scopus 로고
    • Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis
    • (1996) J. Clin. Invest. , vol.98 , pp. 1544-1549
    • Guise, T.A.1
  • 22
    • 0032512898 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of breast and prostate cancer metastasis to bone
    • (1998) Eur. J. Cancer , vol.34 , pp. 240-245
    • Yoneda, T.1
  • 23
    • 0033305222 scopus 로고
    • Breast cancer cells interact with osteoblasts to support osteoclast formation
    • (1990) Endocrinology , vol.140 , pp. 4451-4458
    • Thomas, R.J.1
  • 27
    • 0032429069 scopus 로고    scopus 로고
    • Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor-β in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate
    • (1998) Arthritis Rheum. , vol.41 , pp. 2152-2164
    • Terkeltaub, R.1
  • 29
    • 0034282928 scopus 로고    scopus 로고
    • Crystal structure of human parathyroid hormone 1- 34 at 0.9 a resolution
    • (2000) J. Biol. Chem. , vol.275 , pp. 27238-27244
    • Jin, L.1
  • 30
    • 0034698165 scopus 로고    scopus 로고
    • Minimization of parathyroid hormone. Novel amino-terminal parathyroid hormone fragments with enhanced potency in activating the type-1 parathyroid hormone receptor
    • (2000) J. Biol. Chem. , vol.275 , pp. 21836
    • Shimizu, M.1    Potts, J.T.2    Gardella, T.J.3
  • 34
    • 0034599542 scopus 로고    scopus 로고
    • Extracellular-regulated kinase activation and CA5/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix
    • (2000) J. Cell Biol. , vol.149 , pp. 223-236
    • Cho, Y.1    Klemke, R.L.2
  • 36
    • 0036124520 scopus 로고    scopus 로고
    • Abnormalities in pericytes on blood vessel and endothelial sprouts in tumors
    • (2002) Am. J. Pathol. , vol.160 , pp. 985-1000
    • Morikawa, S.1
  • 37
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • (1999) Nature Med. , vol.5 , pp. 623-628
    • Gerber, H.P.1
  • 38
    • 0346963598 scopus 로고    scopus 로고
    • MMP-9/Gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
    • (1998) Cell , vol.93 , pp. 411-422
    • Vu, T.H.1
  • 40
    • 0033695743 scopus 로고    scopus 로고
    • Parathyroid hormone-related peptide is a potent tumor angiogenic factor
    • (2000) Endocrinology , vol.141 , pp. 4313-4316
    • Akino, K.1
  • 45
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
    • (1999) Mol. Cell , vol.4 , pp. 915-924
    • Eliceiri, B.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.