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Volumn 23, Issue 1-2, 2003, Pages 1-13

Role of peroxisome proliferator-activated receptor γ and its ligands in the control of immune responses

Author keywords

Apoptosis; Cyclopentenone prostaglandins; Dendritic cells; Lymphocytes; Tolerance

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIGEN; ANTINEOPLASTIC AGENT; CELL NUCLEUS RECEPTOR; CYCLOPENTENONE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; LIGAND; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROSTAGLANDIN; PROSTAGLANDIN J2; ROSIGLITAZONE; TROGLITAZONE;

EID: 0038116167     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevImmunol.v23.i12.10     Document Type: Review
Times cited : (56)

References (94)
  • 1
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and Steinman, R. M., Dendritic cells and the control of immunity. Nature 1998; 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 4
    • 0035059416 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cells, tolerance and immunity
    • Heath, W. R., and Carbone, F. R., Cross-presentation, dendritic cells, tolerance and immunity. Annu Rev Immunol 2001; 19:47-64.
    • (2001) Annu Rev Immunol , vol.19 , pp. 47-64
    • Heath, W.R.1    Carbone, F.R.2
  • 5
    • 0034613152 scopus 로고    scopus 로고
    • Dynamics of T lymphocyte responses: Intermediates, effectors, and memory cells
    • Lanzavecchia, A., and Sallusto, F., Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 2000; 290:92-97.
    • (2000) Science , vol.290 , pp. 92-97
    • Lanzavecchia, A.1    Sallusto, F.2
  • 6
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer, P. H., CD95's deadly mission in the immune system. Nature 2000; 407:789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 7
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • Kurts, C., Heath, W. R., Carbone, F. R., Allison, J., Miller, J. F., and Kosaka, H., Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med 1996; 184:923-930.
    • (1996) J Exp Med , vol.184 , pp. 923-930
    • Kurts, C.1    Heath, W.R.2    Carbone, F.R.3    Allison, J.4    Miller, J.F.5    Kosaka, H.6
  • 8
    • 0032811068 scopus 로고    scopus 로고
    • Genetic models of abnormal apoptosis in lymphocytes
    • Refaeli, Y., Van Parijs, L., and Abbas, A. K., Genetic models of abnormal apoptosis in lymphocytes. Immunol Rev 1999; 169:273-282.
    • (1999) Immunol Rev , vol.169 , pp. 273-282
    • Refaeli, Y.1    Van Parijs, L.2    Abbas, A.K.3
  • 9
    • 0034141545 scopus 로고    scopus 로고
    • The nuclear receptor PPAR γ and immunoregulation: PPARγ mediates inhibition of helper T cell responses
    • Clark, R. B., Bishop-Bailey, D., Estrada-Hernandez, T., Hla, T., Puddington, L., and Padula, S. J., The nuclear receptor PPAR γ and immunoregulation: PPARγ mediates inhibition of helper T cell responses. J Immunol 2000; 164:1364-1371.
    • (2000) J Immunol , vol.164 , pp. 1364-1371
    • Clark, R.B.1    Bishop-Bailey, D.2    Estrada-Hernandez, T.3    Hla, T.4    Puddington, L.5    Padula, S.J.6
  • 10
    • 0035062387 scopus 로고    scopus 로고
    • The nuclear receptor PPAR γ is expressed by mouse T lymphocytes and PPAR γ agonists induce apoptosis
    • Harris, S. G., and Phipps, R. P., The nuclear receptor PPAR γ is expressed by mouse T lymphocytes and PPAR γ agonists induce apoptosis. Eur J Immunol 2001; 31:1098-1105.
    • (2001) Eur J Immunol , vol.31 , pp. 1098-1105
    • Harris, S.G.1    Phipps, R.P.2
  • 11
    • 0036467528 scopus 로고    scopus 로고
    • 2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway
    • 2 induces IL-8 production in human T cells by a mitogen-activated protein kinase pathway. J Immunol 2002; 168:1372-1379.
    • (2002) J Immunol , vol.168 , pp. 1372-1379
    • Harris, S.G.1    Smith, R.S.2    Phipps, R.P.3
  • 12
    • 0036164609 scopus 로고    scopus 로고
    • 2, and peroxisome proliferator activated receptor-γ agonists induce apoptosis in transformed, but not normal, human T lineage cells
    • 2, and peroxisome proliferator activated receptor-γ agonists induce apoptosis in transformed, but not normal, human T lineage cells. Immunology 2002; 105:23-34.
    • (2002) Immunology , vol.105 , pp. 23-34
    • Harris, S.G.1    Phipps, R.P.2
  • 13
    • 0037199943 scopus 로고    scopus 로고
    • Thiazolidinedione activation of peroxisome proliferator-activated receptor γ can enhance mitochondrial potential and promote cell survival
    • Wang, Y. L., Frauwirth, K. A., Rangwala, S. M., Lazar, M. A., and Thompson, C. B., Thiazolidinedione activation of peroxisome proliferator-activated receptor γ can enhance mitochondrial potential and promote cell survival. J Biol Chem 2002; 277:31781-31788.
    • (2002) J Biol Chem , vol.277 , pp. 31781-31788
    • Wang, Y.L.1    Frauwirth, K.A.2    Rangwala, S.M.3    Lazar, M.A.4    Thompson, C.B.5
  • 14
    • 0001297403 scopus 로고    scopus 로고
    • Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT
    • Yang, X. Y., Wang, L. H., Chen, T., Hodge, D. R., Resau, J. H., DaSilva, L., and Farrar, W. L., Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor γ (PPARγ) agonists. PPARγ co-association with transcription factor NFAT. J Biol Chem 2000; 275:4541-4544.
    • (2000) J Biol Chem , vol.275 , pp. 4541-4544
    • Yang, X.Y.1    Wang, L.H.2    Chen, T.3    Hodge, D.R.4    Resau, J.H.5    DaSilva, L.6    Farrar, W.L.7
  • 15
    • 0037040293 scopus 로고    scopus 로고
    • Interleukin (IL)-4 indirectly suppresses IL-2 production by human T lymphocytes via peroxisome proliferator-activated receptor γ activated by macrophage-derived 12/15-lipoxygenase ligands
    • Yang, X. Y., Wang, L. H., Mihalic, K., Xiao, W., Chen, T., Li, P., Wahl, L. M., and Farrar, W. L., Interleukin (IL)-4 indirectly suppresses IL-2 production by human T lymphocytes via peroxisome proliferator-activated receptor γ activated by macrophage-derived 12/15-lipoxygenase ligands. J Biol Chem 2002; 277:3973-3978.
    • (2002) J Biol Chem , vol.277 , pp. 3973-3978
    • Yang, X.Y.1    Wang, L.H.2    Mihalic, K.3    Xiao, W.4    Chen, T.5    Li, P.6    Wahl, L.M.7    Farrar, W.L.8
  • 16
    • 0035210586 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ haploin-sufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis
    • Setoguchi, K., Misaki, Y., Terauchi, Y., Yamauchi, T., Kawahata, K., Kadowaki, T., and Yamamoto, K., Peroxisome proliferator-activated receptor-γ haploin-sufficiency enhances B cell proliferative responses and exacerbates experimentally induced arthritis. J Clin Invest 2001; 108:1667-1675.
    • (2001) J Clin Invest , vol.108 , pp. 1667-1675
    • Setoguchi, K.1    Misaki, Y.2    Terauchi, Y.3    Yamauchi, T.4    Kawahata, K.5    Kadowaki, T.6    Yamamoto, K.7
  • 18
    • 0036245961 scopus 로고    scopus 로고
    • Human B lymphocytes and B lymphomas express PPAR-γ and are killed by PPAR-γ agonists
    • Padilla, J., Leung, E., and Phipps, R. P. Human B lymphocytes and B lymphomas express PPAR-γ and are killed by PPAR-γ agonists. Clin Immunol 2002; 103:22-33.
    • (2002) Clin Immunol , vol.103 , pp. 22-33
    • Padilla, J.1    Leung, E.2    Phipps, R.P.3
  • 19
    • 0036062664 scopus 로고    scopus 로고
    • Inhibitory effect of peroxisome proliferator-activated receptor-γ ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39
    • Miyazaki, Y., Tachibana, H., and Yamada, K., Inhibitory effect of peroxisome proliferator-activated receptor-γ ligands on the expression of IgE heavy chain germline transcripts in the human B cell line DND39. Biochem Biophys Res Commun 2002; 295:547-552.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 547-552
    • Miyazaki, Y.1    Tachibana, H.2    Yamada, K.3
  • 21
    • 0034777941 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activators affect the maturation of human monocyte-derived dendritic cells
    • Gosset, P., Charbonnier, A. S., Delerive, P., Fontaine, J., Staels, B., Pestel, J., Tonnel, A. B., and Trottein, F., Peroxisome proliferator-activated receptor γ activators affect the maturation of human monocyte-derived dendritic cells. Eur J Immunol 2001; 31:2857-2865.
    • (2001) Eur J Immunol , vol.31 , pp. 2857-2865
    • Gosset, P.1    Charbonnier, A.S.2    Delerive, P.3    Fontaine, J.4    Staels, B.5    Pestel, J.6    Tonnel, A.B.7    Trottein, F.8
  • 22
    • 0036681640 scopus 로고    scopus 로고
    • Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor γ
    • Nencioni, A., Grunebach, F., Zobywlaski, A., Denzlinger, C., Brugger, W., and Brossart, P., Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor γ. J Immunol 2002; 169:1228-1235.
    • (2002) J Immunol , vol.169 , pp. 1228-1235
    • Nencioni, A.1    Grunebach, F.2    Zobywlaski, A.3    Denzlinger, C.4    Brugger, W.5    Brossart, P.6
  • 23
    • 0036754026 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-γ-independent mechanism: Regulation by inflammatory and T cell-derived stimuli
    • Nencioni, A., Lauber, K., Grunebach, F., Brugger, W., Denzlinger, C., Wesselborg, S., and Brossart, P., Cyclopentenone prostaglandins induce caspase activation and apoptosis in dendritic cells by a PPAR-γ-independent mechanism: regulation by inflammatory and T cell-derived stimuli. Exp Hematol 2002; 30:1020-1028.
    • (2002) Exp Hematol , vol.30 , pp. 1020-1028
    • Nencioni, A.1    Lauber, K.2    Grunebach, F.3    Brugger, W.4    Denzlinger, C.5    Wesselborg, S.6    Brossart, P.7
  • 24
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne, B., and Wahli, W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr Rev 1999; 20:649-688.
    • (1999) Endocr Rev , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 25
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARs in health and disease
    • Kersten, S., Desvergne, B., and Wahli, W., Roles of PPARs in health and disease. Nature 2000; 405:421-424.
    • (2000) Nature , vol.405 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 26
    • 0034406481 scopus 로고    scopus 로고
    • PPAR-γ agonists: Therapeutic role in diabetes, inflammation and cancer
    • Murphy, G. J., and Holder, J. C., PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer. Trends Pharmacol Sci 2000; 21:469-474.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 469-474
    • Murphy, G.J.1    Holder, J.C.2
  • 27
    • 0034943192 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ expression in human malignant and normal brain, breast and prostate-derived cells
    • Nwankwo, J. O., and Robbins, M. E., Peroxisome proliferator-activated receptor-γ expression in human malignant and normal brain, breast and prostate-derived cells. Prostaglandins Leukot Essent Fatty Acids 2001; 64:241-245.
    • (2001) Prostaglandins Leukot Essent Fatty Acids , vol.64 , pp. 241-245
    • Nwankwo, J.O.1    Robbins, M.E.2
  • 28
    • 0029152375 scopus 로고
    • Isolation of the human peroxisome proliferator activated receptor γ cDNA: Expression in hematopoietic cells and chromosomal mapping
    • Greene, M. E., Blumberg, B., McBride, O. W., Yi, H. F., Kronquist, K., Kwan, K., Hsieh, L., Greene, G., and Nimer, S. D., Isolation of the human peroxisome proliferator activated receptor γ cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expr 1995; 4:281-299.
    • (1995) Gene Expr , vol.4 , pp. 281-299
    • Greene, M.E.1    Blumberg, B.2    McBride, O.W.3    Yi, H.F.4    Kronquist, K.5    Kwan, K.6    Hsieh, L.7    Greene, G.8    Nimer, S.D.9
  • 29
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • Jiang, C., Ting, A. T., and Seed, B., PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 30
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J., and Glass, C. K., The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 1998; 391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 32
    • 0024432264 scopus 로고
    • 2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissues
    • 2 production is likely antigen-presenting cells. Localization of glutathione-requiring prostaglandin D synthetase in histiocytes, dendritic, and Kupffer cells in various rat tissues. J Immunol 1989; 143:2982-2989.
    • (1989) J Immunol , vol.143 , pp. 2982-2989
    • Urade, Y.1    Ujihara, M.2    Horiguchi, Y.3    Ikai, K.4    Hayaishi, O.5
  • 35
    • 0035942212 scopus 로고    scopus 로고
    • IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression
    • Spanbroek, R., Hildner, M., Kohler, A., Muller, A., Zintl, F., Kuhn, H., Radmark, O., Samuelsson, B., and Habenicht, A. J., IL-4 determines eicosanoid formation in dendritic cells by down-regulation of 5-lipoxygenase and up-regulation of 15-lipoxygenase 1 expression. Proc Natl Acad Sci U S A 2001; 98:5152-5157.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5152-5157
    • Spanbroek, R.1    Hildner, M.2    Kohler, A.3    Muller, A.4    Zintl, F.5    Kuhn, H.6    Radmark, O.7    Samuelsson, B.8    Habenicht, A.J.9
  • 36
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla, A., Barak, Y., Nagy, L., Liao, D., Tontonoz, P., and Evans, R. M., PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001; 7:48-52.
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 38
    • 0030788683 scopus 로고    scopus 로고
    • The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium
    • Rubartelli, A., Poggi, A., and Zocchi, M. R., The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium. Eur J Immunol 1997; 27:1893-1900.
    • (1997) Eur J Immunol , vol.27 , pp. 1893-1900
    • Rubartelli, A.1    Poggi, A.2    Zocchi, M.R.3
  • 39
    • 0036908619 scopus 로고    scopus 로고
    • Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter
    • Girnun, G. D., Domann, F. E., Moore, S. A., and Robbins, M. E., Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Mol Endocrinol 2002; 16:2793-2801.
    • (2002) Mol Endocrinol , vol.16 , pp. 2793-2801
    • Girnun, G.D.1    Domann, F.E.2    Moore, S.A.3    Robbins, M.E.4
  • 43
    • 0031013395 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
    • Lehmann, J. M., Lenhard, J. M., Oliver, B. B., Ringold, G. M., and Kliewer, S. A., Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem 1997; 272:3406-3410.
    • (1997) J Biol Chem , vol.272 , pp. 3406-3410
    • Lehmann, J.M.1    Lenhard, J.M.2    Oliver, B.B.3    Ringold, G.M.4    Kliewer, S.A.5
  • 45
    • 0033950209 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins - New allies in the war on inflammation
    • Willoughby, D. A., Moore, A. R., and Colville-Nash, P. R., Cyclopentenone prostaglandins - new allies in the war on inflammation. Nat Med 2000; 6:137-138.
    • (2000) Nat Med , vol.6 , pp. 137-138
    • Willoughby, D.A.1    Moore, A.R.2    Colville-Nash, P.R.3
  • 46
    • 0035053973 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins: New insights on biological activities and cellular targets
    • Straus, D. S., and Glass, C. K., Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev 2001; 21:185-210.
    • (2001) Med Res Rev , vol.21 , pp. 185-210
    • Straus, D.S.1    Glass, C.K.2
  • 47
    • 0035839603 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway
    • Mullally, J. E., Moos, P.J., Edes, K., and Fitzpatrick, F. A., Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway. J Biol Chem 2001; 276:30366-30373.
    • (2001) J Biol Chem , vol.276 , pp. 30366-30373
    • Mullally, J.E.1    Moos, P.J.2    Edes, K.3    Fitzpatrick, F.A.4
  • 49
    • 0034610759 scopus 로고    scopus 로고
    • Antiinflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
    • Rossi, A., Kapahi, P., Natoli, G., Takahashi, T., Chen, Y., Karin, M., and Santoro, M. G., Antiinflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase. Nature 2000; 403:103-108.
    • (2000) Nature , vol.403 , pp. 103-108
    • Rossi, A.1    Kapahi, P.2    Natoli, G.3    Takahashi, T.4    Chen, Y.5    Karin, M.6    Santoro, M.G.7
  • 51
    • 0035851123 scopus 로고    scopus 로고
    • 2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors
    • 2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. J Biol Chem 2001; 276:38152-39158.
    • (2001) J Biol Chem , vol.276 , pp. 38152-39158
    • Li, L.1    Tao, J.2    Davaille, J.3    Feral, C.4    Mallat, A.5    Rieusset, J.6    Vidal, H.7    Lotersztajn, S.8
  • 52
    • 0035853707 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress
    • Kondo, M., Oya-Ito, T., Kumagai, T., Osawa, T., and Uchida, K., Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress. J Biol Chem 2001; 276:12076-12083.
    • (2001) J Biol Chem , vol.276 , pp. 12076-12083
    • Kondo, M.1    Oya-Ito, T.2    Kumagai, T.3    Osawa, T.4    Uchida, K.5
  • 53
    • 0034547853 scopus 로고    scopus 로고
    • Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages
    • Hortelano, S., Castrillo, A., Alvarez, A. M., and Bosca, L., Contribution of cyclopentenone prostaglandins to the resolution of inflammation through the potentiation of apoptosis in activated macrophages. J Immunol 2000; 165:6525-6531.
    • (2000) J Immunol , vol.165 , pp. 6525-6531
    • Hortelano, S.1    Castrillo, A.2    Alvarez, A.M.3    Bosca, L.4
  • 54
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A., Luo, C., and Hogan, P. G., Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 1997; 15:707-747.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 55
    • 0037096205 scopus 로고    scopus 로고
    • 2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of IκBα degradation using a peroxisome proliferator-activated receptor-γ-independent mechanism
    • 2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of IκBα degradation using a peroxisome proliferator-activated receptor-γ-independent mechanism. J Immunol 2002; 168:6232-6243.
    • (2002) J Immunol , vol.168 , pp. 6232-6243
    • Ward, C.1    Dransfield, I.2    Murray, J.3    Farrow, S.N.4    Haslett, C.5    Rossi, A.G.6
  • 60
    • 0031014560 scopus 로고    scopus 로고
    • Functions of IL-4 and control of its expression
    • Brown, M. A., and Hural, J., Functions of IL-4 and control of its expression. Crit Rev Immunol 1997; 17:1-32.
    • (1997) Crit Rev Immunol , vol.17 , pp. 1-32
    • Brown, M.A.1    Hural, J.2
  • 62
    • 0032864097 scopus 로고    scopus 로고
    • The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii
    • Caamano, J., Alexander, J., Craig, L., Bravo, R., and Hunter, C. A., The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii. J Immunol 1999; 163:4453-4461.
    • (1999) J Immunol , vol.163 , pp. 4453-4461
    • Caamano, J.1    Alexander, J.2    Craig, L.3    Bravo, R.4    Hunter, C.A.5
  • 63
    • 0036681795 scopus 로고    scopus 로고
    • A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling
    • Zhou, J., Zhang, J., Lichtenheld, M. G., and Meadows, G. G., A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling. J Immunol 2002; 169:1319-1325.
    • (2002) J Immunol , vol.169 , pp. 1319-1325
    • Zhou, J.1    Zhang, J.2    Lichtenheld, M.G.3    Meadows, G.G.4
  • 64
    • 0035170432 scopus 로고    scopus 로고
    • Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells
    • Albert, M. L., Jegathesan, M., and Darnell, R. B., Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells. Nat Immunol 2001; 2:1010-1017.
    • (2001) Nat Immunol , vol.2 , pp. 1010-1017
    • Albert, M.L.1    Jegathesan, M.2    Darnell, R.B.3
  • 65
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family
    • Weih, F., Carrasco, D., Durham, S. K., Barton, D. S., Rizzo, C. A., Ryseck, R. P., Lira, S. A., and Bravo, R., Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family. Cell 1995; 80:331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8
  • 66
  • 67
    • 0033571320 scopus 로고    scopus 로고
    • Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway
    • Ashany, D., Savir, A., Bhardway, N., and Elkon, K. B., Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway. J Immunol 1999; 163:5303-5311.
    • (1999) J Immunol , vol.163 , pp. 5303-5311
    • Ashany, D.1    Savir, A.2    Bhardway, N.3    Elkon, K.B.4
  • 69
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus Interleukin 4 and down-regulated by tumor necrosis factor α
    • Sallusto, F., and Lanzavecchia, A., Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus Interleukin 4 and down-regulated by tumor necrosis factor α. J Exp Med 1994; 179:1109-1118.
    • (1994) J Exp Med , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 72
    • 0036781052 scopus 로고    scopus 로고
    • NF-κB regulation in the immune system
    • Li, Q., and Verma, I. M., NF-κB regulation in the immune system. Nat Rev Immunol 2002; 2:725-734.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 73
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh, S., and Karin, M., Missing pieces in the NF-κB puzzle. Cell 2002; 109 Suppl:S81-96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 75
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB
    • Chung, S. W., Kang, B. Y., Kim, S. H., Pak, Y. K., Cho, D., Trinchieri, G., and Kim, T. S., Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB. J Biol Chem 2000; 275:32681-32687.
    • (2000) J Biol Chem , vol.275 , pp. 32681-32687
    • Chung, S.W.1    Kang, B.Y.2    Kim, S.H.3    Pak, Y.K.4    Cho, D.5    Trinchieri, G.6    Kim, T.S.7
  • 76
    • 0035853840 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300
    • Subbaramaiah, K., Lin, D. T., Hart, J. C., and Dannenberg, A J., Peroxisome proliferator-activated receptor γ ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300. J Biol Chem 2001; 276:12440-12448.
    • (2001) J Biol Chem , vol.276 , pp. 12440-12448
    • Subbaramaiah, K.1    Lin, D.T.2    Hart, J.C.3    Dannenberg, A.J.4
  • 78
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V., and Baldwin, A. S. Jr., NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 79
    • 0036094148 scopus 로고    scopus 로고
    • Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases
    • Yang, T. T., Xiong, Q., Enslen, H., Davis, R.J., and Chow, C. W., Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol Cell Biol 2002; 22:3892-3904.
    • (2002) Mol Cell Biol , vol.22 , pp. 3892-3904
    • Yang, T.T.1    Xiong, Q.2    Enslen, H.3    Davis, R.J.4    Chow, C.W.5
  • 80
    • 0037072826 scopus 로고    scopus 로고
    • Constitutive activation of peroxisome proliferator-activated receptor-γ suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells
    • Wang, N., Verna, L., Chen, N. G., Chen, J., Li, H., Forman, B. M., and Stemerman, M. B., Constitutive activation of peroxisome proliferator-activated receptor-γ suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells. J Biol Chem 2002; 277:34176-34181.
    • (2002) J Biol Chem , vol.277 , pp. 34176-34181
    • Wang, N.1    Verna, L.2    Chen, N.G.3    Chen, J.4    Li, H.5    Forman, B.M.6    Stemerman, M.B.7
  • 86
    • 0035866756 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptors α and γ inhibit chemically induced colitis and formation of aberrant crypt foci in rats
    • Tanaka, T., Kohno, H., Yoshitani, S., Takashima, S., Okumura, A., Murakami, A., and Hosokawa, M., Ligands for peroxisome proliferator-activated receptors α and γ inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res 2001; 61:2424-2428.
    • (2001) Cancer Res , vol.61 , pp. 2424-2428
    • Tanaka, T.1    Kohno, H.2    Yoshitani, S.3    Takashima, S.4    Okumura, A.5    Murakami, A.6    Hosokawa, M.7
  • 89
    • 0037010478 scopus 로고    scopus 로고
    • Role of peroxisome proliferator-activated receptor γ and retinoid X receptor heterodimer in hepatogastroenterological diseases
    • Dubuquoy, L., Dharancy, S., Nutten, S., Pettersson, S., Auwerx, J., and Desreumaux, P., Role of peroxisome proliferator-activated receptor γ and retinoid X receptor heterodimer in hepatogastroenterological diseases. Lancet 2002; 60:1410-1418.
    • (2002) Lancet , vol.60 , pp. 1410-1418
    • Dubuquoy, L.1    Dharancy, S.2    Nutten, S.3    Pettersson, S.4    Auwerx, J.5    Desreumaux, P.6
  • 90
    • 0035881317 scopus 로고    scopus 로고
    • Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
    • Palakurthi, S. S., Aktas, H., Grubissich, L. M., Mortensen, R. M., and Halperin, J. A., Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation. Cancer Res 2001; 61:6213-6218.
    • (2001) Cancer Res , vol.61 , pp. 6213-6218
    • Palakurthi, S.S.1    Aktas, H.2    Grubissich, L.M.3    Mortensen, R.M.4    Halperin, J.A.5
  • 91
    • 0034192904 scopus 로고    scopus 로고
    • Regulation of TRAIL-induced apoptosis by transcription factors
    • Goke, R., Goke, A., Goke, B., and Chen, Y., Regulation of TRAIL-induced apoptosis by transcription factors. Cell Immunol 2000; 201:77-82.
    • (2000) Cell Immunol , vol.201 , pp. 77-82
    • Goke, R.1    Goke, A.2    Goke, B.3    Chen, Y.4
  • 92
    • 0034641932 scopus 로고    scopus 로고
    • From bench to clinic with apoptosis-based therapeutic agents
    • Nicholson, D. W., From bench to clinic with apoptosis-based therapeutic agents. Nature 2000; 407:810-816.
    • (2000) Nature , vol.407 , pp. 810-816
    • Nicholson, D.W.1
  • 93
    • 0035743494 scopus 로고    scopus 로고
    • Pioglitazone inhibits growth of carcinoid cells and promotes TRAIL-induced apoptosis by induction of p21waf1/cip1
    • Goke, R., Goke, A., Goke, B., El-Deiry, W. S., and Chen, Y., Pioglitazone inhibits growth of carcinoid cells and promotes TRAIL-induced apoptosis by induction of p21waf1/cip1. Digestion 2001; 64:75-80.
    • (2001) Digestion , vol.64 , pp. 75-80
    • Goke, R.1    Goke, A.2    Goke, B.3    El-Deiry, W.S.4    Chen, Y.5
  • 94
    • 0037151079 scopus 로고    scopus 로고
    • An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
    • Jun 21
    • Kim Y, Suh N, Sporn M, Reed JC. An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. J Biol Chem 2002 Jun 21; 277(25):22320-22329.
    • (2002) J Biol Chem , vol.277 , Issue.25 , pp. 22320-22329
    • Kim, Y.1    Suh, N.2    Sporn, M.3    Reed, J.C.4


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