-
1
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peruxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer, S. A., K. Umesono, D. J. Noonan, R. A. Heyman, and R. M. Evans. 1992. Convergence of 9-cis retinoic acid and peruxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358:771.
-
(1992)
Nature
, vol.358
, pp. 771
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
2
-
-
0029731662
-
Peroxisome prolferator-activated receptors: A nuclear receptor signaling pathway in lipid physiology
-
Lemberger, T., B. Desvergne, and W. Wahli. 1996. Peroxisome prolferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Annu. Rev. Cell. Dev. Biol. 12:1355.
-
(1996)
Annu. Rev. Cell. Dev. Biol.
, vol.12
, pp. 1355
-
-
Lemberger, T.1
Desvergne, B.2
Wahli, W.3
-
3
-
-
0028180070
-
mPPARγ 2: Tissue-specific regulator of an adipocyte enhancer
-
Tontonoz, P., E. Hu, R. A. Graves, A. I. Budavari, and B. M. Spiegelman. 1994. mPPARγ 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev. 8:1224.
-
(1994)
Genes Dev.
, vol.8
, pp. 1224
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
4
-
-
0027749599
-
Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
-
Zhu, Y., K. Alvares, Q. Huang, M. Sambasiva Rao, and J. Reddy. 1993. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J. Biol. Chem. 268:26817.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26817
-
-
Zhu, Y.1
Alvares, K.2
Huang, Q.3
Sambasiva Rao, M.4
Reddy, J.5
-
5
-
-
0028641559
-
Stimulation of adipogeneisis in fibroblasts by PPARy 2, a lipid-activated transcription factor
-
Tontonoz, P., E. Hu, and B. M. Spiegelman, 1994. Stimulation of adipogeneisis in fibroblasts by PPARy 2, a lipid-activated transcription factor. Cell 79:1147.
-
(1994)
Cell
, vol.79
, pp. 1147
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
6
-
-
0028015713
-
Peroxisome proliferator-activated receptor (PPAR) γ: Adipose-predominant expression and induction early in adipocyte differentiation
-
Chawla, A., E. J. Schwartz, D. D. Dimaculangan, and M. A. Lazar. 1994. Peroxisome proliferator-activated receptor (PPAR) γ: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135:798.
-
(1994)
Endocrinology
, vol.135
, pp. 798
-
-
Chawla, A.1
Schwartz, E.J.2
Dimaculangan, D.D.3
Lazar, M.A.4
-
7
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distributon of PPAR-α, -β, and -γ in the adult rat
-
Braissant O., F. Foufelle, C. Scotto, M. Dauca, and W. Wahli. 1996. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distributon of PPAR-α, -β, and -γ in the adult rat. Endocrinology 137:354.
-
(1996)
Endocrinology
, vol.137
, pp. 354
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauca, M.4
Wahli, W.5
-
8
-
-
0029152375
-
Isolation of the human peroxisome proliferator activated receptor γ cDNA: Expression in hematopoietic cells and chromosomal mapping
-
Greene M. E., B. Blumberg, O. W. McBride, H. F. Yi, K. Kronquist, L. Hsieh, G. Greene, and S. D. Nimer. 1995. Isolation of the human peroxisome proliferator activated receptor γ cDNA: expression in hematopoietic cells and chromosomal mapping. Gene Expr. 4:281.
-
(1995)
Gene Expr.
, vol.4
, pp. 281
-
-
Greene, M.E.1
Blumberg, B.2
McBride, O.W.3
Yi, H.F.4
Kronquist, K.5
Hsieh, L.6
Greene, G.7
Nimer, S.D.8
-
9
-
-
0029102676
-
Structural organization of mouse peroxisome proliferator-activated receptor γ (PPARγ) gene: Alternative promoter use and ditferent splicing yield two mPPARγ isoforms
-
Zhu, Y., C. Qi, J. R. Korenberg, X. N. Chen, D. Noya, M. Sambasiva-Rao, and J. K. Reddy. 1995. Structural organization of mouse peroxisome proliferator-activated receptor γ (PPARγ) gene: alternative promoter use and ditferent splicing yield two mPPARγ isoforms. Proc. Natl. Acad. Sci. USA 92:7921.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7921
-
-
Zhu, Y.1
Qi, C.2
Korenberg, J.R.3
Chen, X.N.4
Noya, D.5
Sambasiva-Rao, M.6
Reddy, J.K.7
-
10
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator activated receptor γ
-
Lehman, J. M., L. B. Moore, T. A. Smith-Oliver, W. O. Wilkinson, T. M. Wilson, and S. A. Kliewere. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator activated receptor γ. J. Biol. Chem. 270:12953.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953
-
-
Lehman, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkinson, W.O.4
Wilson, T.M.5
Kliewere, S.A.6
-
13
-
-
0031013395
-
Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs
-
Lehmann, J. M., J. M. Lenhard, B. B. Oliver, G. M. Ringold, and S. A. Kliewer. 1997. Peroxisome proliferator-activated receptors α and γ are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J. Biol. Chem. 272: 3406.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3406
-
-
Lehmann, J.M.1
Lenhard, J.M.2
Oliver, B.B.3
Ringold, G.M.4
Kliewer, S.A.5
-
14
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPARγ
-
Mueller, E., P. Sarraf, P. Tontonoz, R. M. Evans, K. J. Martin, M. Zhang, C. Fletcher, S. Singer, and B. M. Spiegelman. 1998. Terminal differentiation of human breast cancer through PPARγ. Mol. Cell 1:465.
-
(1998)
Mol. Cell
, vol.1
, pp. 465
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
Fletcher, C.7
Singer, S.8
Spiegelman, B.M.9
-
15
-
-
0030612740
-
PPARγ induces cell cycle withdrawal: Inhibition of E2/DP DNA-binding activity via down-regulation of PP2A
-
Altiok, S., M. Xu, and B. M. Spiegelman. 1997. PPARγ induces cell cycle withdrawal: inhibition of E2/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 11:1987.
-
(1997)
Genes Dev.
, vol.11
, pp. 1987
-
-
Altiok, S.1
Xu, M.2
Spiegelman, B.M.3
-
16
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
Sarraf, P., E. Mueller, D. Jones, F. J. King, D. J. DeAngelo, J. B. Partridge, S. A. Holden, L. B. Chen, S. Singer, C. Fletcher, and B. M. Spiegelman. 1998. Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat. Med 4:1046.
-
(1998)
Nat. Med
, vol.4
, pp. 1046
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
King, F.J.4
DeAngelo, D.J.5
Partridge, J.B.6
Holden, S.A.7
Chen, L.B.8
Singer, S.9
Fletcher, C.10
Spiegelman, B.M.11
-
18
-
-
0031667938
-
Activators of the nuclear receptor PPARy enhance colon polyp formation
-
Saez, E., P. Tontonoz, M. C. Nelson, J. G. Alvarez, U. T. Ming, S. M. Baird, V. A. Thomazy. and R. M. Evans, 1998. Activators of the nuclear receptor PPARy enhance colon polyp formation. Nat. Med. 4:1058.
-
(1998)
Nat. Med.
, vol.4
, pp. 1058
-
-
Saez, E.1
Tontonoz, P.2
Nelson, M.C.3
Alvarez, J.G.4
Ming, U.T.5
Baird, S.M.6
Thomazy, V.A.7
Evans, R.M.8
-
19
-
-
0031694577
-
Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6j-APCmin/+ mice
-
Lefebvre, A., I. Chen, P. Desreumaux, J. Najib, J. Fruchart, K. Geboes, M. Briggs, R. Heyman, and J. Auwerx. 1998. Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6j-APCmin/+ mice. Nat. Med. 4:1053.
-
(1998)
Nat. Med.
, vol.4
, pp. 1053
-
-
Lefebvre, A.1
Chen, I.2
Desreumaux, P.3
Najib, J.4
Fruchart, J.5
Geboes, K.6
Briggs, M.7
Heyman, R.8
Auwerx, J.9
-
20
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P., L. Nagy, J. G. A. Alvarez, V. A. Triomazy, and R. M. Evans, 1998. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93:241.
-
(1998)
Cell
, vol.93
, pp. 241
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
Triomazy, V.A.4
Evans, R.M.5
-
21
-
-
0032560545
-
Expression of the peroxisome proliferator-activated receptor γ in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
-
Ricote, M., J. Huang, L. Fajas, A. Li, J. Welch, J. Najib, J. Witztum, J. Auwerx, W. Palinski, and C. K. Glass. 1998. Expression of the peroxisome proliferator-activated receptor γ in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc: Natl. Acad. Sci. USA 95:7614.
-
(1998)
Proc: Natl. Acad. Sci. USA
, vol.95
, pp. 7614
-
-
Ricote, M.1
Huang, J.2
Fajas, L.3
Li, A.4
Welch, J.5
Najib, J.6
Witztum, J.7
Auwerx, J.8
Palinski, W.9
Glass, C.K.10
-
22
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote, M., A. C. Li, T. M. Willson, C. J. Kelly, and C. K. Glass. 1998. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391:79.
-
(1998)
Nature
, vol.391
, pp. 79
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
23
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C. , A. T. Ting, and B. Seed. 1998. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82.
-
(1998)
Nature
, vol.391
, pp. 82
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
24
-
-
0032565868
-
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPAR-γ activators
-
Staels, B., W. Koenig, A. Habib, R. Merval. M.-Lebret, I. P. Torra, P. Delerive, G. Chinetti, J. C. Fruchart, J. Najib, J. Maclouf, and A. Tedgui. 1998. Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPAR-γ activators. Nature 393:790.
-
(1998)
Nature
, vol.393
, pp. 790
-
-
Staels, B.1
Koenig, W.2
Habib, A.3
Merval, R.4
Lebret, M.5
Torra, I.P.6
Delerive, P.7
Chinetti, G.8
Fruchart, J.C.9
Najib, J.10
Maclouf, J.11
Tedgui, A.12
-
25
-
-
0032475922
-
Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
-
Chinetti G., S. Griglio, M. Antonucci, I. P. Torra, P. Delerive, Z. Majd, J. C. Fruchart, J. Chapman, J. Najib, and B. Stael. 1998. Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. J. Biol. Chem. 273:25573.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25573
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
Torra, I.P.4
Delerive, P.5
Majd, Z.6
Fruchart, J.C.7
Chapman, J.8
Najib, J.9
Stael, B.10
-
26
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy, L., P. Tontonoz, J. G. Alvarez, H. Chen, and R. M. Evans. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93:229.
-
(1998)
Cell
, vol.93
, pp. 229
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
27
-
-
0032528350
-
Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: Correlation with induction of heme oxygenase I
-
Colville-Nash, P. R., S. S. Qureshi, D. Willis, and D. A. Willoughby. 1998. inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: correlation with induction of heme oxygenase I. J. Immunol. 161:978.
-
(1998)
J. Immunol.
, vol.161
, pp. 978
-
-
Colville-Nash, P.R.1
Qureshi, S.S.2
Willis, D.3
Willoughby, D.A.4
-
28
-
-
0033000906
-
Inducible cyclooxygenase may have anti-inflammatory properties
-
Gilroy, D. W., P. R. Colville-Nash, W. J. Chivers, M. J. Paul-Clark, and D. A. Willoughby. 1999. Inducible cyclooxygenase may have anti-inflammatory properties. Nat. Med. 6:698.
-
(1999)
Nat. Med.
, vol.6
, pp. 698
-
-
Gilroy, D.W.1
Colville-Nash, P.R.2
Chivers, W.J.3
Paul-Clark, M.J.4
Willoughby, D.A.5
-
29
-
-
0023685532
-
Subtypes of helper cells: Noninflammatory type 1 helper T cells
-
Wong, R. L., N. H. Ruddle, S. J. Padula, E. G. Lingenheld, C. M. Bergman, R. V. Rugen, D. L. Epstein, and R. B. Clark. 1988. Subtypes of helper cells: noninflammatory type 1 helper T cells. J. Immunol. 141:3329.
-
(1988)
J. Immunol.
, vol.141
, pp. 3329
-
-
Wong, R.L.1
Ruddle, N.H.2
Padula, S.J.3
Lingenheld, E.G.4
Bergman, C.M.5
Rugen, R.V.6
Epstein, D.L.7
Clark, R.B.8
-
30
-
-
0026090664
-
Identification of encephalitogenic Vβ-4-bearing T cells in SJL mice: Further evidence for the V-region disease hypothesis?
-
Padula, S. J., E. G. Lingenheld, P. R. Stabach, C. H. J. Chou, D. H. Kono, and R. B. Clark. 1991. Identification of encephalitogenic Vβ-4-bearing T cells in SJL mice: further evidence for the V-region disease hypothesis? J. Immunol. 146:879.
-
(1991)
J. Immunol.
, vol.146
, pp. 879
-
-
Padula, S.J.1
Lingenheld, E.G.2
Stabach, P.R.3
Chou, C.H.J.4
Kono, D.H.5
Clark, R.B.6
-
31
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156
-
-
Chomczynski, P.1
Sacchi, N.2
-
32
-
-
0032540013
-
PPARγ in monocytes: Less pain, any gain?
-
Spiegelman, B. M. 1998. PPARγ in monocytes: less pain, any gain? Cell 93:153.
-
(1998)
Cell
, vol.93
, pp. 153
-
-
Spiegelman, B.M.1
-
33
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters, J. M., N. Hennuyer, B. Staels, J. C. Fruchart, J. C. Fievet, F. J. Gonzales, and J. Auwerx. 1997. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J. Biol. Chem. 272:27307.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27307
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.C.4
Fievet, J.C.5
Gonzales, F.J.6
Auwerx, J.7
-
35
-
-
0032484224
-
A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties
-
Reginato, M. J., S. T. Bailey, S. L. Krakow, C. Minami, S. Ishii, H. Tanaka, and M. A. Lazar. 1998. A potent antidiabetic thiazolidinedione with unique peroxisome proliferator-activated receptor γ-activating properties. J. Biol. Chem. 273: 32679.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32679
-
-
Reginato, M.J.1
Bailey, S.T.2
Krakow, S.L.3
Minami, C.4
Ishii, S.5
Tanaka, H.6
Lazar, M.A.7
-
36
-
-
13044286786
-
A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation
-
Oberfield, J. I., J. L. Collins, C. P. Holmes, D. M. Goreham, J. P. Cooper, J. E. Cobb, J. M. Lenhard, E. A. Hull-Ryde, C. P. Mohr, S. G. Blanchard, et al. 1999. A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation. Proc: Natl. Acad. Sci. USA 96:6102.
-
(1999)
Proc: Natl. Acad. Sci. USA
, vol.96
, pp. 6102
-
-
Oberfield, J.I.1
Collins, J.L.2
Holmes, C.P.3
Goreham, D.M.4
Cooper, J.P.5
Cobb, J.E.6
Lenhard, J.M.7
Hull-Ryde, E.A.8
Mohr, C.P.9
Blanchard, S.G.10
|