15-Deoxy-Δ12,14-prostaglandin J2 Inhibition of NF-κB-DNA Binding through Covalent Modification of the p50 Subunit

Journal of Biological Chemistry

Volumn 276, Issue 38, 2001, Pages 35530-35536

  Cernuda Morollón, Eva ^a   Pineda Molina, Estela ^a   Javier Canada F ^b   Pérez Sala, Dolores ^a,c  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^c Depto Estructura/Funcion Proteinas   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DNA; KETONES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUTAGENESIS; PRECIPITATION (CHEMICAL);

PROSTAGLANDINS; SIGNALING PATHWAYS;

PROTEINS;

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; AVIDIN; CYCLOPENTENONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTAGLANDIN J2; PROTEIN P50; TRANSCRIPTION FACTOR; 15 DEOXY DELTA(12,14) PROSTAGLANDIN J2; 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J2; DNA; DRUG DERIVATIVE; GLUTATHIONE; PROSTAGLANDIN D2;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; COVALENT BOND; DNA BINDING; GENE MUTATION; IMMUNE RESPONSE; INFLAMMATORY CELL; MASS SPECTROMETRY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DRUG ANTAGONISM; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING;

BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; GLUTATHIONE; HELA CELLS; HUMANS; MASS SPECTROMETRY; NF-KAPPA B; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN D2; PROTEIN BINDING;

EID: 0035929592     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104518200     Document Type: Article

References (39)

1. Baeuerle, P. A., and Baichwal, V. R. (1997) Adv. Immunol. 65, 111-137
2. Pahl, H. L. (1999) Oncogene 18, 6853-6866
3. Baeuerle, P. A. (1998) Curr. Biol. 8, R19-R22
4. Karin, M. (1999) Oncogene 18, 6867-6874
5. Ghosh, S., May, M. J., and Kopp, E. B. (1998) Annu. Rev. Immunol. 16, 225-260
6. Zhong, H., Yang, H. S., Erdjument-Bromage, H., Tempst, P., and Ghosh, S. (1997) Cell 89, 413-424
7. Sizemore, N., Leung, S., and Stark, G. R. (1999) Mol. Cell. Biol. 19, 4798-4805
8. Martin, A. G., and Fresno, M. (2000) J. Biol. Chem. 275, 24383-24391
9. Li, C. C., Dai, R. M., Chen, E., and Longo, D. L. (1994) J. Biol. Chem. 269, 30089-30092
10. Mackichan, M. L., Logeat, F., and Israel, A. (1996) J. Biol. Chem. 271, 6084-6091
11. Mathews, J. R., Botting, C. H., Panieo, M., Morris, H. R., and Hay, R. T. (1996) Nucleic Acids Res. 24, 2236-2242
12. Toledano, M. B., Ghosh, D., Trinh, F., and Leonard, W. J. (1993) Mol. Cell. Biol. 13, 852-860
13. Janssen-Heininger, Y. M., Poynter, M. E., and Baeuerle, P. A. (2000) Free Radic. Biol. Med. 28, 1317-1327
14. Seibert, K., Zhang, Y., Leahy, K., Hauser, S., Masferrer, J., Perkins, W., Lee, L., and Isakson, P. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 12013-12017
15. Crofford, L. J., Wilder, R. L., Ristimaki, A. P., Sano, H., Remmers, E. F., Epps, H. R., and Hla, T. (1994) J. Clin. Invest. 93, 1095-1101
16. Appleton, I., Tomlinson, A., and Willoughby, D. A. (1996) Adv. Pharmacol. 35, 27-78
17. Gilroy, D. W., Colville-Nash, P. R., Willis, D., Chivers, J., Paul-Clark, M. J., and Willoughby, D. A. (1999) Nat. Med. 5, 698-701
18. Fukushima, M., Kato, T., Narumiya, S., Mizushima, Y., Sasaki, H., Terashima, Y., Nishiyama, Y., and Santoro, M. G. (1989) Adv. Prostaglandin Thromboxane Leukotriene Res. 19, 415-418
19. Kim, I. K., Lee, J. H., Sohn, H. W., Kim, H. S., and Kim, S. H. (1993) FEBS Lett. 321, 209-214
20. Ricote, M., Li, A. C., Willson, T. M., Kelly, C. J., and Glass, C. K. (1998) Nature 391, 79-82
21. Petrova, T. V., Akama, K. T., and Eldik, L. J. V. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 4668-4673
22. Li, M., Pascual, G., and Glass, C. K. (2000) Mol. Cell. Biol. 20, 4699-4707
23. Castrillo, A., Díaz-Guerra, M. J., Hortelano, S., Martín-Sanz, P., and Boscá, L. (2000) Mol. Cell. Biol. 20, 1692-1698
24. Rossi, A., Kapahi, P., Natoli, G., Takahashi, T., Chen, Y., Karin, M., and Santoro, M. G. (2000) Nature 403, 103-108
25. Straus, D. S., Pascual, G., Li, M., Welch, J. S., Ricote, M., Hsiang, C. H., Sengchanthalangsy, L. L., Ghosh, G., and Glass, C. K. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4844-4849
26. Inoue, H., Tanabe, T., and Umesono, K. (2000) J. Biol. Chem. 275, 28028-28032
27. Hortelano, S., Castrillo, A., Alvarez, A. M., and Boscá, L. (2000) J. Immunol. 165, 6525-6531
28. Klatt, P., Pineda-Molina, E., Pérez-Sala, D., and Lamas, S. (2000) Biochem. J. 349, 567-578
29. Díaz-Cazorla, M., Pérez-Sala, D., and Lamas, S. (1999) J. Am. Soc. Nephrol. 10, 943-952
30. Parker, J. (1996) Prostaglandins 50, 359-375
31. Narumiya, S., Ohno, K., Fukushima, M., and Fujiwara, M. (1987) J. Pharmacol. Exp. Ther. 242, 306-311
32. Noyori, R., and Suzuki, M. (1993) Science 259, 44-45
33. Atsmon, J., Freeman, M. L., Meredith, M. J., Sweetman, B. J., and Roberts, L. J., II. (1990) Cancer Res. 50, 1879-1885
34. Mihm, S., Galter, D., and Dröge, W. (1995) FASEB J. 9, 246-252
35. Forman, B. M., Tontonoz, P., Chen, J., Brun, R. P., Spiegelman, B. M., and Evans, R. M. (1995) Cell 83, 803-812
36. Santoro, M. G. (1997) Trends Microbiol. 5, 276-281
37. Kersten, S., Desvergne, B., and Wahli, W. (2000) Nature 405, 421-424
38. Atsmon, J., Sweetman, B. J., Baertschi, S. W., Harris, T. M., and Roberts, L. J., II. (1990) Biochemistry 29, 3760-3765
39. Chen, Y., Morrow, J. D., and Roberts, L. J., II. (1999) J. Biol. Chem. 274, 10863-10868