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Volumn 169, Issue , 1999, Pages 273-282

Genetic models of abnormal apoptosis in lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; APOPTOSIS; GENETIC MODEL; INFLAMMATION; KNOCKOUT MOUSE; LYMPHOCYTE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

EID: 0032811068     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1999.tb01322.x     Document Type: Review
Times cited : (35)

References (48)
  • 1
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-tolerance in the immune system: Turning lymphocytes off
    • 1. Van Parijs L, Abbas AK. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. Science 1998;280:243-248.
    • (1998) Science , vol.280 , pp. 243-248
    • Van Parijs, L.1    Abbas, A.K.2
  • 2
    • 0028927607 scopus 로고
    • The Fas death factor
    • 2. Nagata S, Goldstein P. The Fas death factor. Science; 1995;267:1449-1456.
    • (1995) Science , vol.267 , pp. 1449-1456
    • Nagata, S.1    Goldstein, P.2
  • 3
    • 0031805451 scopus 로고    scopus 로고
    • Death-inducing functions of ligands of the tumor necrosis factor family: A Sanhedrin verdict
    • 3. Wallach D, Kovalenko AV, Varfolomeev EE, Boldin MP. Death-inducing functions of ligands of the tumor necrosis factor family: a Sanhedrin verdict. Curr Opin Immunol 1998;10:279-288.
    • (1998) Curr Opin Immunol , vol.10 , pp. 279-288
    • Wallach, D.1    Kovalenko, A.V.2    Varfolomeev, E.E.3    Boldin, M.P.4
  • 4
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • 4. Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science 1998;281:1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 5
    • 0032575723 scopus 로고    scopus 로고
    • Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
    • 5. Yang X, Chang HY, Baltimore P. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science 1998;281:1355-1357.
    • (1998) Science , vol.281 , pp. 1355-1357
    • Yang, X.1    Chang, H.Y.2    Baltimore, P.3
  • 6
    • 0028915454 scopus 로고
    • Regulation of lymphocyte survival by the bcl-2 gene family
    • 6. Cory S. Regulation of lymphocyte survival by the bcl-2 gene family. Annu Rev Immunol 1995;13:513-543.
    • (1995) Annu Rev Immunol , vol.13 , pp. 513-543
    • Cory, S.1
  • 7
    • 0028980902 scopus 로고
    • Fas and fas ligand: Lpr and gld mutations
    • 7. Nagata S, Suda T. Fas and Fas ligand: lpr and gld mutations. Immonul Today 1995;16:39-43.
    • (1995) Immonul Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 8
    • 0032493910 scopus 로고    scopus 로고
    • Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
    • 8. Kuida K, et al. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 1998;94:325-337.
    • (1998) Cell , vol.94 , pp. 325-337
    • Kuida, K.1
  • 9
    • 0032546387 scopus 로고    scopus 로고
    • Fas mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort-1
    • 9. Zhang J, Cado D, Chen A, Kabra NH, Winoto A. Fas mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort-1. Nature 1998;392:296-300.
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 10
    • 7144263731 scopus 로고    scopus 로고
    • FADD: Essential for embryo development and signaling from some, but not all, inducers of apoptosis
    • 10. Yeh WC, et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998;279:1954-1958.
    • (1998) Science , vol.279 , pp. 1954-1958
    • Yeh, W.C.1
  • 11
    • 0032143986 scopus 로고    scopus 로고
    • Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo-i, and DR3 and is lethal prenatally
    • 11. Varfolomeev EE, et al. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo-I, and DR3 and is lethal prenatally. Immunity 1998;9:267-276.
    • (1998) Immunity , vol.9 , pp. 267-276
    • Varfolomeev, E.E.1
  • 12
    • 0026487088 scopus 로고
    • The lpr and gld genes in systemic autoimmunity: Life and death in the Fas lane
    • 12. Cohen PL, Eisenberg RA. The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane. Immunol Today 1992;13:427-428.
    • (1992) Immunol Today , vol.13 , pp. 427-428
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 14
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • 14. Singer GG, Abbas AK. The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994;1:365-371.
    • (1994) Immunity , vol.1 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 15
    • 0032031457 scopus 로고    scopus 로고
    • Functional roles of Fas and Bcl-1-regulated apoptosis of T lymphocytes
    • 15. Van Parijs L, Biuckians A, Abbas AK. Functional roles of Fas and Bcl-1-regulated apoptosis of T lymphocytes. J Immunol 1998;160:2065-2071.
    • (1998) J Immunol , vol.160 , pp. 2065-2071
    • Van Parijs, L.1    Biuckians, A.2    Abbas, A.K.3
  • 16
    • 0031054632 scopus 로고    scopus 로고
    • Negative selection in the thymus includes semimature T cells
    • 16. Kishimoto H, Sprent J. Negative selection in the thymus includes semimature T cells. J Exp Med 1997;185:263-271.
    • (1997) J Exp Med , vol.185 , pp. 263-271
    • Kishimoto, H.1    Sprent, J.2
  • 17
    • 0029076561 scopus 로고
    • + T cells
    • + T cells. Nature 1995;376:181-184.
    • (1995) Nature , vol.376 , pp. 181-184
    • Rathmell, J.C.1
  • 18
    • 0028789148 scopus 로고
    • Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice
    • 18. Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK, Marshak Rothstein A. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity 1995;4:509-519.
    • (1995) Immunity , vol.4 , pp. 509-519
    • Jacobson, B.A.1    Panka, D.J.2    Nguyen, K.A.3    Erikson, J.4    Abbas, A.K.5    Marshak Rothstein, A.6
  • 20
    • 0029025441 scopus 로고
    • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
    • 20. Fisher GH, et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995;81:935-946.
    • (1995) Cell , vol.81 , pp. 935-946
    • Fisher, G.H.1
  • 21
    • 0029006893 scopus 로고
    • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
    • 21. Rieux-Laucat F, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995;268:1347-1349.
    • (1995) Science , vol.268 , pp. 1347-1349
    • Rieux-Laucat, F.1
  • 22
    • 0030708809 scopus 로고    scopus 로고
    • Host modifier genes affect mouse autoimmunity induced by the lpr gene
    • 22. Wang Y. Nose M, Kamoto T, Nishimura M, Hiai H. Host modifier genes affect mouse autoimmunity induced by the lpr gene. Am J Pathol 1997;151:1791-1798.
    • (1997) Am J Pathol , vol.151 , pp. 1791-1798
    • Wang, Y.1    Nose, M.2    Kamoto, T.3    Nishimura, M.4    Hiai, H.5
  • 24
    • 0032472916 scopus 로고    scopus 로고
    • A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
    • 24. Newton K, Harris AW, Bath ML, Smith K. GC, Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J 1998;17:706 -718.
    • (1998) EMBO J , vol.17 , pp. 706-718
    • Newton, K.1    Harris, A.W.2    Bath, M.L.3    Smith, K.G.C.4    Strasser, A.5
  • 25
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell ipoptosis and peripheral tolerance
    • 25. Van Parijs L, Ibraghimov A, Abbas AK. The roles of costimulation and Fas in T cell ipoptosis and peripheral tolerance. Immunity 1996;4:321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 27
    • 0031726359 scopus 로고    scopus 로고
    • Inhibition of fas death signals by FLIPs
    • 27. Tschopp J, Irmler M, Thome M. Inhibition of fas death signals by FLIPs. Curr Opin Immunol 1998;10:552-528.
    • (1998) Curr Opin Immunol , vol.10 , pp. 552-1528
    • Tschopp, J.1    Irmler, M.2    Thome, M.3
  • 28
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • 28. Irmler M, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-195.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1
  • 29
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxin shock, yet succumb to L. monocytogenes infection
    • 29. Pfeffer K, et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxin shock, yet succumb to L. monocytogenes infection. Cell 1993;73:457-467.
    • (1993) Cell , vol.73 , pp. 457-467
    • Pfeffer, K.1
  • 30
    • 0028784289 scopus 로고
    • Interleukin-2 receptor a chain regulates the size and content of he peripheral lymphoid compartment
    • 30. Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interleukin-2 receptor a chain regulates the size and content of he peripheral lymphoid compartment. Immunity 1995;3:541-530.
    • (1995) Immunity , vol.3 , pp. 541-1530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 31
    • 0029028363 scopus 로고
    • Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β
    • 31. Suzuki H, et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β. Science 1995;268:1472-1476.
    • (1995) Science , vol.268 , pp. 1472-1476
    • Suzuki, H.1
  • 32
    • 0027369395 scopus 로고
    • Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
    • 31. Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993;75:253-261.
    • (1993) Cell , vol.75 , pp. 253-261
    • Sadlack, B.1    Merz, H.2    Schorle, H.3    Schimpl, A.4    Feller, A.C.5    Horak, I.6
  • 33
    • 0031906218 scopus 로고    scopus 로고
    • Lymphoid hyperplasia, autoimmunity, and compromised intestinal intracpithelial lymphocyte development in colitis-free gnotobiotic Il.-2-deficient mice
    • 33. Contractor NV, et al. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intracpithelial lymphocyte development in colitis-free gnotobiotic Il.-2-deficient mice. J Immunol 1998;160:385-394.
    • (1998) J Immunol , vol.160 , pp. 385-394
    • Contractor, N.V.1
  • 34
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse αβ T lymphocytes for apoptosis
    • 34. Lenardo MJ. Interleukin-2 programs mouse αβ T lymphocytes for apoptosis. Nature 1991;353:858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 35
    • 0031569514 scopus 로고    scopus 로고
    • Functional responses and apoptosis of CD25 (IL-2R α)-deficient T cells expressing a trangenic antigen receptor
    • 35. Van Parijs L, Biukians A, Ibragimov A, Alt FW, Willerford DM, Abbas AK. Functional responses and apoptosis of CD25 (IL-2R α)-deficient T cells expressing a trangenic antigen receptor. J Immunol 1997;158:3738-3745.
    • (1997) J Immunol , vol.158 , pp. 3738-3745
    • Van Parijs, L.1    Biukians, A.2    Ibragimov, A.3    Alt, F.W.4    Willerford, D.M.5    Abbas, A.K.6
  • 36
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
    • 36. Refaeli Y, Van Parijs L, London CA, Tschopp J, Abbas AK. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998;8:615-623.
    • (1998) Immunity , vol.8 , pp. 615-623
    • Refaeli, Y.1    Van Parijs, L.2    London, C.A.3    Tschopp, J.4    Abbas, A.K.5
  • 37
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998;188:287-296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 38
    • 0029962080 scopus 로고    scopus 로고
    • The interleukin-2 receptor γ chain: Its role in the multiple cytokine receptor complexes and T cell development in XSCID
    • 38. Sugamura K, Asao H, Kondo M, Tanaka N, Ishii N, Ohbo K, Nakamura M, Takeshita T. The interleukin-2 receptor γ chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID. Annu Rev Immunol 1996; 14:179-205.
    • (1996) Annu Rev Immunol , vol.14 , pp. 179-205
    • Sugamura, K.1    Asao, H.2    Kondo, M.3    Tanaka, N.4    Ishii, N.5    Ohbo, K.6    Nakamura, M.7    Takeshita, T.8
  • 39
    • 15144356187 scopus 로고    scopus 로고
    • Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene
    • 39. Denny P, et al. Mapping of the IDDM locus Idd3 to a 0.35-cM interval containing the interleukin-2 gene. Diabetes 1997;46:695-700.
    • (1997) Diabetes , vol.46 , pp. 695-700
    • Denny, P.1
  • 40
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • 40. Vyse TJ, Todd JA. Genetic analysis of autoimmune disease. Cell 1996;85:311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 41
    • 0028920079 scopus 로고
    • Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells
    • 41. Rothstein TL, et al. Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature 1995;374:163-165.
    • (1995) Nature , vol.374 , pp. 163-165
    • Rothstein, T.L.1
  • 42
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • 42. Adams JM. Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 1998;281:1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 44
    • 0025939204 scopus 로고
    • Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
    • 44. Strasser, A, et al. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sci USA 1991;88:8661-8665.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8661-8665
    • Strasser, A.1
  • 45
    • 0028117306 scopus 로고
    • Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene
    • 45. Strasser A. Harris AW, von Boehmer H, Cory S. Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene. Proc Natl Acad Sci USA 1994;91:1376-1380.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1376-1380
    • Strasser, A.1    Harris, A.W.2    Von Boehmer, H.3    Cory, S.4
  • 46
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • 46. Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993;75:229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 47
    • 0028922885 scopus 로고
    • Massive cell death of immature hematopoietic cells and neurons in Bcl-2-deficient mice
    • 47. Motoyama N, et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-2-deficient mice. Science 1995;167:1506-1510.
    • (1995) Science , vol.167 , pp. 1506-1510
    • Motoyama, N.1
  • 48
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathways and Bcl-2 regulate T cell responses to model self and foreign antigens
    • 48. Van Parijs L, Peterson DA, Abbas AK. The Fas/Fas ligand pathways and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 1998;8:265-274.
    • (1998) Immunity , vol.8 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3


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