메뉴 건너뛰기




Volumn 7, Issue 1, 2001, Pages 41-47

The role of PPAR-γ in macrophage differentiation and cholesterol uptake

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE; CD36 ANTIGEN; CYTOKINE; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; SCAVENGER RECEPTOR; TROGLITAZONE;

EID: 0035139016     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/83328     Document Type: Article
Times cited : (462)

References (47)
  • 3
    • 0031589638 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ. A key regulator of adipogenesis and systemic insulin sensitivity
    • (1997) Eur. J. Med. Res. , vol.2 , pp. 457-464
    • Spiegelman, B.M.1
  • 4
    • 0034696412 scopus 로고    scopus 로고
    • Expression and function of PPAR-γ in rat and human vascular smooth muscle cells
    • (2000) Circulation , vol.101 , pp. 1311-1318
    • Law, R.E.1
  • 5
    • 0034141545 scopus 로고    scopus 로고
    • The nuclear receptor PPAR-γ and immunoregulation: PPAR-γ mediates inhibition of helper T cell responses
    • (2000) J. Immunol. , vol.164 , pp. 1364-1371
    • Clark, R.B.1
  • 6
    • 0028972025 scopus 로고
    • 2 is a ligand for the adipocyte determination factor PPAR-γ
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1
  • 7
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR-γ)
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1
  • 8
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1
  • 13
    • 0031870652 scopus 로고    scopus 로고
    • Macrophages in human atheroma contain PPAR-γ differentiation-dependent peroxisomal proliferator-activated receptor γ (PPAR-γ) expression and reduction of MMP-9 activity through PPAR-γ activation in mononuclear phagocytes in vitro
    • (1998) Am. J. Pathol. , vol.153 , pp. 17-23
    • Marx, N.1    Sukhova, G.2    Murphy, C.3    Libby, P.4    Plutzky, J.5
  • 14
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor γ (PPAR-γ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoproteins
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7614-7619
    • Ricote, M.1
  • 15
    • 0034705071 scopus 로고    scopus 로고
    • CLA-1/SR-B1 is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors
    • (2000) Circulation , vol.101 , pp. 2411-2417
    • Chinetti, G.1
  • 18
    • 0034610759 scopus 로고    scopus 로고
    • Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of lκB kinase
    • (2000) Nature , vol.403 , pp. 103-108
    • Rossi, A.1
  • 22
  • 23
    • 0033213637 scopus 로고    scopus 로고
    • PPAR-γ is required for placental, cardiac, and adipose tissue development
    • (1999) Mol. Cell , vol.4 , pp. 585-595
    • Barak, Y.1
  • 24
    • 0033213631 scopus 로고    scopus 로고
    • PPAR-γ is required for the differentiation of adipose tissue in vivo and in vitro
    • (1999) Mol. Cell , vol.4 , pp. 611-617
    • Rosen, E.D.1
  • 25
    • 0033212964 scopus 로고    scopus 로고
    • PPAR-γ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
    • (1999) Mol. Cell , vol.4 , pp. 597-609
    • Kubota, N.1
  • 27
    • 0034650330 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor γ does not inhibit IL-6 or TNF-α responses of macrophages to lipopolysaccharide in vitro or in vivo
    • (2000) J. Immunol. , vol.164 , pp. 1046-1054
    • Thieringer, R.1
  • 28
    • 0033595261 scopus 로고    scopus 로고
    • Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
    • (1999) Nature , vol.400 , pp. 378-382
    • Huang, J.T.1
  • 29
    • 0034123963 scopus 로고    scopus 로고
    • Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-γ
    • (2000) J. Lipid Res. , vol.41 , pp. 688-696
    • Feng, J.1
  • 32
    • 0033516477 scopus 로고    scopus 로고
    • A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
    • (1999) J. Biol. Chem. , vol.274 , pp. 19055-19062
    • Febbraio, M.1
  • 33
    • 0034101821 scopus 로고    scopus 로고
    • Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice
    • (2000) J. Clin. Invest. , vol.105 , pp. 1049-1056
    • Febbraio, M.1
  • 36
    • 0034284918 scopus 로고    scopus 로고
    • Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
    • (2000) Science , vol.289 , pp. 1524-1529
    • Repa, J.J.1
  • 37
    • 0033864582 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor-deficient mice
    • (2000) J. Clin. Invest. , vol.106 , pp. 523-531
    • Li, A.C.1
  • 38
    • 0031054699 scopus 로고    scopus 로고
    • Cardiac and glycemic benefits of troglitazone treatment in NIDDM. The troglitazone study group
    • (1997) Diabetes , vol.46 , pp. 433-439
    • Ghazzi, M.N.1
  • 39
    • 0029902629 scopus 로고    scopus 로고
    • Inhibition of oxidation of low density lipoprotein by troglitazone
    • (1996) Atherosclerosis , vol.123 , pp. 227-234
    • Noguchi, N.1
  • 41
    • 0029861097 scopus 로고    scopus 로고
    • Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
    • (1996) J. Clin. Invest. , vol.98 , pp. 1897-1905
    • Law, R.E.1
  • 42
    • 0032006966 scopus 로고    scopus 로고
    • Troglitazone suppresses intimal formation following balloon injury in insulin-resistant Zucker fatty rats
    • (1998) Atherosclerosis , vol.136 , pp. 275-279
    • Shinohara, E.1
  • 43
    • 0025253834 scopus 로고
    • An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8810-8814
    • Freeman, M.1
  • 45
    • 17044441930 scopus 로고    scopus 로고
    • Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse
    • (2000) Nature Genet. , vol.24 , pp. 381-386
    • Lindblad-Toh, K.1
  • 46
    • 0030698029 scopus 로고    scopus 로고
    • Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum
    • (1997) J. Lipid Res. , vol.38 , pp. 1973-1987
    • Jacobs, N.L.1
  • 47
    • 0027288279 scopus 로고
    • Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors
    • (1993) J. Lipid Res. , vol.34 , pp. 983-1000
    • Ashkenas, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.