메뉴 건너뛰기




Volumn 17, Issue 1, 1997, Pages 1-32

Functions of IL-4 and control of its expression

Author keywords

basophils; IL 4; mast cells; NF AT; T cells; TCR and FceRI mediated signaling mechanisms; transcriptional regulation

Indexed keywords

FC RECEPTOR; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR;

EID: 0031014560     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: 10.1615/critrevimmunol.v17.i1.10     Document Type: Article
Times cited : (304)

References (257)
  • 1
    • 0025764757 scopus 로고
    • Interleukin 4: A prototypic immunoregulatory cytokine
    • Paul, W. E., Interleukin 4: a prototypic immunoregulatory cytokine, Blood, 77, 1859, 1991.
    • (1991) Blood , vol.77 , pp. 1859
    • Paul, W.E.1
  • 3
    • 0023124410 scopus 로고
    • Receptors for B cell stimulatory factor-1 expressed on cells of haematopoietic lineage
    • Ohara, J. and Paul, W. E., Receptors for B cell stimulatory factor-1 expressed on cells of haematopoietic lineage, Nature (London), 325, 537, 1987.
    • (1987) Nature (London) , vol.325 , pp. 537
    • Ohara, J.1    Paul, W.E.2
  • 4
    • 1842266333 scopus 로고
    • Characterization of the high affinity cell-surface receptor for murine B-cell stimulating factor 1
    • Park, L. S., Friend, D., Grabstein, K., and Urdal, D. L., Characterization of the high affinity cell-surface receptor for murine B-cell stimulating factor 1, Proc. Natl. Acad. Sci. U.S.A., 84, 1669, 1987.
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 1669
    • Park, L.S.1    Friend, D.2    Grabstein, K.3    Urdal, D.L.4
  • 5
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
    • Kondo, M., Takeshita, T., and Ishii, N., Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4, Science, 262, 1874, 1993.
    • (1993) Science , vol.262 , pp. 1874
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3
  • 9
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides, H. and Reich, N. C., Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4, Science, 262, 1265, 1993.
    • (1993) Science , vol.262 , pp. 1265
    • Kotanides, H.1    Reich, N.C.2
  • 10
    • 0028262965 scopus 로고
    • STF-IL-4: A novel IL-4 induced signal transducing factor
    • Schindler, C., Kashleva, H., Pernis, A., Pine, R., and Rothman, P., STF-IL-4: a novel IL-4 induced signal transducing factor, EMBO J., 13, 1350, 1994.
    • (1994) EMBO J. , vol.13 , pp. 1350
    • Schindler, C.1    Kashleva, H.2    Pernis, A.3    Pine, R.4    Rothman, P.5
  • 11
    • 0029057858 scopus 로고
    • Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis
    • Quelle, F. W., Simoda, K., Thierfelder, W., Fischer, C., Kim, A., Ruben, S. M., Cleveland, J. L., Pierce, J. H., Keegan, A. D., and Nelms, K., Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis, Mol. Cell. Biol., 15, 3336, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3336
    • Quelle, F.W.1    Simoda, K.2    Thierfelder, W.3    Fischer, C.4    Kim, A.5    Ruben, S.M.6    Cleveland, J.L.7    Pierce, J.H.8    Keegan, A.D.9    Nelms, K.10
  • 12
    • 0029156064 scopus 로고
    • Characterization of the interleukin-4 nuclear activated factor/STAT and its activation independent of the insulin receptor substrate proteins
    • Kotanides, H., Moczygemba, M., White, M. F., and Reich, N. C., Characterization of the interleukin-4 nuclear activated factor/STAT and its activation independent of the insulin receptor substrate proteins, J. Biol. Chem., 270, 19481, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19481
    • Kotanides, H.1    Moczygemba, M.2    White, M.F.3    Reich, N.C.4
  • 15
    • 0029881543 scopus 로고    scopus 로고
    • Abnormal IL-4 production by atopic T cells is reflected in altered nuclear protein interactions with an IL-4 transcriptional regulatory element
    • Chan, S. C., Brown, M. A., Li, S.-H., Stevens, S. R., and Hanifin, J. C., Abnormal IL-4 production by atopic T cells is reflected in altered nuclear protein interactions with an IL-4 transcriptional regulatory element, J. Invest. Dermatol., 106, 1131, 1996.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 1131
    • Chan, S.C.1    Brown, M.A.2    Li, S.-H.3    Stevens, S.R.4    Hanifin, J.C.5
  • 17
    • 0027251027 scopus 로고
    • An activation responsive element in the murine interleukin-4 gene is the site of an inducible DNA-protein interaction
    • Tara, D., Weiss, D. L., and Brown, M. A., An activation responsive element in the murine interleukin-4 gene is the site of an inducible DNA-protein interaction, J. Immunol., 151, 3617, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 3617
    • Tara, D.1    Weiss, D.L.2    Brown, M.A.3
  • 20
    • 0042927891 scopus 로고
    • Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B cell stimulatory factor-1, that expresses B-cell and T-cell stimulating activities
    • Yokota, T., Otsuka, T., Mosmann, T., Banchereau, J., DeFrance, T., Blanchard, D., DeVries, J. E., Lee, F., and Arai, K., Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B cell stimulatory factor-1, that expresses B-cell and T-cell stimulating activities, Proc. Natl. Acad. Sci. U.S.A., 83, 1, 1986.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 1
    • Yokota, T.1    Otsuka, T.2    Mosmann, T.3    Banchereau, J.4    DeFrance, T.5    Blanchard, D.6    DeVries, J.E.7    Lee, F.8    Arai, K.9
  • 22
    • 0023696554 scopus 로고
    • The IL-4 gene maps to chromosome 11, near the gene encoding IL-3
    • D'Eustachio, P., Brown, M. A., Watson, C., and Paul W. E., The IL-4 gene maps to chromosome 11, near the gene encoding IL-3, J. Immunol., 141, 3067, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 3067
    • D'Eustachio, P.1    Brown, M.A.2    Watson, C.3    Paul, W.E.4
  • 23
    • 0024582777 scopus 로고
    • The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11
    • Lee, J. S., Campbell, H. D., Kozak, C. A., and Young, I. G., The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11, Somat. Cell. Mol. Genet., 15, 143, 1989.
    • (1989) Somat. Cell. Mol. Genet. , vol.15 , pp. 143
    • Lee, J.S.1    Campbell, H.D.2    Kozak, C.A.3    Young, I.G.4
  • 24
    • 0026731946 scopus 로고
    • The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes
    • Morgan, J. G., Dolganov, G. M., Robbins, S. E., Hinton, L. M., and Lovett, M., The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes, Nucl. Acids Res., 20, 5173, 1992.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 5173
    • Morgan, J.G.1    Dolganov, G.M.2    Robbins, S.E.3    Hinton, L.M.4    Lovett, M.5
  • 25
    • 0028910112 scopus 로고
    • Tandem arrangement of human gene for interleukin-4 and interleukin-13: Resemblance in their organization
    • Smirnov, D. V., Smirnova, M. G., Korobko, V. G., and Frolova, E. I., Tandem arrangement of human gene for interleukin-4 and interleukin-13: resemblance in their organization, Gene, 155, 277, 1995.
    • (1995) Gene , vol.155 , pp. 277
    • Smirnov, D.V.1    Smirnova, M.G.2    Korobko, V.G.3    Frolova, E.I.4
  • 26
    • 0024582587 scopus 로고
    • Molecular organization of the cytokine gene cluster involving human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5
    • van Leeuwen, B. H., Martinsom, M. E., Webb, G. C., and G., Y. I., Molecular organization of the cytokine gene cluster involving human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5, Blood, 73, 1142, 1989.
    • (1989) Blood , vol.73 , pp. 1142
    • Van Leeuwen, B.H.1    Martinsom, M.E.2    Webb, G.C.3    G., Y.I.4
  • 27
    • 0028999779 scopus 로고
    • Signal transduction and cytokine production in human basophils
    • MacGlashan, D. W., Signal transduction and cytokine production in human basophils, Chem. Immunol., 61, 88, 1995.
    • (1995) Chem. Immunol. , vol.61 , pp. 88
    • MacGlashan, D.W.1
  • 28
    • 0029000726 scopus 로고
    • Early events in mast cell signaling
    • Scharenberg, A. M. and Kinet, J. P., Early events in mast cell signaling, Chem. Immunol., 61, 72, 1995.
    • (1995) Chem. Immunol. , vol.61 , pp. 72
    • Scharenberg, A.M.1    Kinet, J.P.2
  • 29
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., Signal transduction by lymphocyte antigen receptors, Cell, 76, 263, 1994.
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1
  • 30
    • 0029655781 scopus 로고    scopus 로고
    • Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex
    • Weiss, D. L., Hural, J., Tara, D., Timmerman, L. A., Henkel, G., and Brown, M. A., Nuclear factor of activated T cells is associated with a mast cell interleukin 4 transcription complex, Mol. Cell. Biol., 16, 228, 1996.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 228
    • Weiss, D.L.1    Hural, J.2    Tara, D.3    Timmerman, L.A.4    Henkel, G.5    Brown, M.A.6
  • 31
    • 0027939672 scopus 로고
    • PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer
    • Henkel, G. and Brown, M. A., PU.1 and GATA: components of a mast cell-specific interleukin 4 intronic enhancer, Proc. Natl. Acad. Sci. U.S.A., 91, 7737, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 7737
    • Henkel, G.1    Brown, M.A.2
  • 32
    • 0020081969 scopus 로고
    • Identification of a T-cell derived B cell growth factor distinct from interleukin 2
    • Howard, M., Farrar, J., Hilfiker, M., Johnson, B., Takatsu, K., and Paul, W. E., Identification of a T-cell derived B cell growth factor distinct from interleukin 2, J. Exp. Med., 155, 914, 1982.
    • (1982) J. Exp. Med. , vol.155 , pp. 914
    • Howard, M.1    Farrar, J.2    Hilfiker, M.3    Johnson, B.4    Takatsu, K.5    Paul, W.E.6
  • 33
    • 0021680253 scopus 로고
    • Increased expression of Ia antigens on resting B cells: An additional role for B cell growth factor
    • Noelle, R., Krammer, P. H., Ohara, J., Uhr, J. W., and Vitteta, E. S., Increased expression of Ia antigens on resting B cells: an additional role for B cell growth factor, Proc. Natl. Acad. Sci. U.S.A., 81, 6149, 1984.
    • (1984) Proc. Natl. Acad. Sci. U.S.A. , vol.81 , pp. 6149
    • Noelle, R.1    Krammer, P.H.2    Ohara, J.3    Uhr, J.W.4    Vitteta, E.S.5
  • 35
    • 0025326718 scopus 로고
    • Allergen-directed expression of Fc receptors for IgE (CD23) is modulated by interleukin-4 and interferon-γ
    • Prinz, J. C., Bauer, X., Mazur, G., and Rieber, E. P., Allergen-directed expression of Fc receptors for IgE (CD23) is modulated by interleukin-4 and interferon-γ, Eur. J. Immunol., 20, 1259, 1990.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1259
    • Prinz, J.C.1    Bauer, X.2    Mazur, G.3    Rieber, E.P.4
  • 38
    • 0027317909 scopus 로고
    • Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4
    • Illera, V. A., Perandones, C. E., Stunz, L. L., Mower, D. A. J., and Ashman, R. F., Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4, J. Immunol., 151, 2965, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 2965
    • Illera, V.A.1    Perandones, C.E.2    Stunz, L.L.3    Mower, D.A.J.4    Ashman, R.F.5
  • 39
    • 0026754538 scopus 로고
    • Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-1 expression
    • Dancescu, M., Rubio-Truijillo, M., Biron, G., Bron, D., Delespesse, G., and Sarfati, M., Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-1 expression, J. Exp. Med., 176, 1319, 1992.
    • (1992) J. Exp. Med. , vol.176 , pp. 1319
    • Dancescu, M.1    Rubio-Truijillo, M.2    Biron, G.3    Bron, D.4    Delespesse, G.5    Sarfati, M.6
  • 40
    • 0027936671 scopus 로고
    • Interleukin-5 (IL-5) increases spontaneous apoptosis of B cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression and is inhibited by IL-4
    • Mainou-Fowler, T., Craig, V. A., Copplestone, J. A., Hamon, M. D., and Prentice, A. G., Interleukin-5 (IL-5) increases spontaneous apoptosis of B cell chronic lymphocytic leukemia cells in vitro independently of bcl-2 expression and is inhibited by IL-4, Blood, 84, 2297, 1994.
    • (1994) Blood , vol.84 , pp. 2297
    • Mainou-Fowler, T.1    Craig, V.A.2    Copplestone, J.A.3    Hamon, M.D.4    Prentice, A.G.5
  • 41
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kuhn, R., Rajewsky, K., and Muller, W., Generation and analysis of interleukin-4 deficient mice, Science, 254, 707, 1991.
    • (1991) Science , vol.254 , pp. 707
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 42
    • 0025287114 scopus 로고
    • Interleukin-4 induces changes in the chromatin structure of the γ1 switch region in resting B cells before switch recombination
    • Berton, M. T. and Vitetta, E. S., Interleukin-4 induces changes in the chromatin structure of the γ1 switch region in resting B cells before switch recombination, J. Exp. Med., 172, 375, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 375
    • Berton, M.T.1    Vitetta, E.S.2
  • 43
    • 0024231914 scopus 로고
    • Mitogen plus interleukin 4 induction of Ce transcripts in B lymphoid cells
    • Rothman, P., Lutzker, S., Cook, W., Coffman, R., and Alt, F., Mitogen plus interleukin 4 induction of Ce transcripts in B lymphoid cells, J. Exp. Med., 168, 2385, 1989.
    • (1989) J. Exp. Med. , vol.168 , pp. 2385
    • Rothman, P.1    Lutzker, S.2    Cook, W.3    Coffman, R.4    Alt, F.5
  • 44
    • 0027173826 scopus 로고
    • Regulation of the expression of human Cε germline transcript: Identification of a novel IL-4 responsive element
    • Ichiki, T., Takahashi, W., and Watanabe, T., Regulation of the expression of human Cε germline transcript: identification of a novel IL-4 responsive element, J. Immunol., 150, 5408, 1993.
    • (1993) J. Immunol. , vol.150 , pp. 5408
    • Ichiki, T.1    Takahashi, W.2    Watanabe, T.3
  • 45
    • 0025942519 scopus 로고
    • Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line ε transcripts
    • Rothman, P., Li, S. C., Gorham, B., Glimcher, L., Alt, F., and Boothby, M., Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line ε transcripts, Mol. Cell. Biol., 11, 5551, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5551
    • Rothman, P.1    Li, S.C.2    Gorham, B.3    Glimcher, L.4    Alt, F.5    Boothby, M.6
  • 47
    • 0027931577 scopus 로고
    • Interleukin-4 - A dual regulatory factor in hematopoiesis
    • Sonoda, Y., Interleukin-4 - a dual regulatory factor in hematopoiesis, Leuk. Lymph., 14, 231, 1994.
    • (1994) Leuk. Lymph. , vol.14 , pp. 231
    • Sonoda, Y.1
  • 49
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain, S. L., Weinberg, A. D., English, M., and Huston, G., IL-4 directs the development of Th2-like helper effectors, J. Immunol., 145, 3796, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 3796
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 50
    • 0026712313 scopus 로고
    • The presence of interleukin-4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T-cell receptor transgenic mice
    • Seder, R. A., Paul, W. E., Davis, M. M., and Fazekas de St. Groth, B., The presence of interleukin-4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T-cell receptor transgenic mice, J. Exp. Med., 176, 1091, 1992.
    • (1992) J. Exp. Med. , vol.176 , pp. 1091
    • Seder, R.A.1    Paul, W.E.2    Davis, M.M.3    Fazekas De St. Groth, B.4
  • 51
    • 0027164561 scopus 로고
    • Switch of CD8 T cells to noncytolytic CD8- CD4- cells that make Th2 cytokines and help B cells
    • Erard, F., Wild, M.-T., Garcia-Sanz, J. A., and LeGros, G., Switch of CD8 T cells to noncytolytic CD8- CD4- cells that make Th2 cytokines and help B cells, Science, 260, 1802, 1993.
    • (1993) Science , vol.260 , pp. 1802
    • Erard, F.1    Wild, M.-T.2    Garcia-Sanz, J.A.3    LeGros, G.4
  • 52
    • 1442270503 scopus 로고
    • Interleukin 4 is a growth factor for activated thymocytes: Possible role in T cell ontogeny
    • Zlotnick, A., Ransom, J., Frank, G., Fischer, M., and Howard, M., Interleukin 4 is a growth factor for activated thymocytes: possible role in T cell ontogeny, Proc. Natl. Acad. Sci. U.S.A., 84, 3856, 1987.
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 3856
    • Zlotnick, A.1    Ransom, J.2    Frank, G.3    Fischer, M.4    Howard, M.5
  • 53
    • 0023069555 scopus 로고
    • Recombinant interleukin4/BSF-1 promotes the growth and differentiation of intrathymic T cell precursors from fetal mice in vitro
    • Palacios, R., Sideras, P., and von Boehmer, H., Recombinant interleukin4/BSF-1 promotes the growth and differentiation of intrathymic T cell precursors from fetal mice in vitro. EMBO J., 6, 91, 1987.
    • (1987) EMBO J. , vol.6 , pp. 91
    • Palacios, R.1    Sideras, P.2    Von Boehmer, H.3
  • 54
    • 0023876886 scopus 로고
    • IL-4 (B cell stimulatory factor 1) exhibits thymocyte growth factor activity in the presence of IL-2
    • Carding, S. and Bottomly, K., IL-4 (B cell stimulatory factor 1) exhibits thymocyte growth factor activity in the presence of IL-2, J. Immunol., 140, 1519, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 1519
    • Carding, S.1    Bottomly, K.2
  • 55
    • 0024237623 scopus 로고
    • IL-4 (B cell-stimulatory factor 1) regulates multiple aspects of influenza virus-specific cell-mediated immunity
    • Horohov, D. W., Crim, J. A., Smith, P. L., and Siegel, J. P., IL-4 (B cell-stimulatory factor 1) regulates multiple aspects of influenza virus-specific cell-mediated immunity, J. Immunol., 141, 4217, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 4217
    • Horohov, D.W.1    Crim, J.A.2    Smith, P.L.3    Siegel, J.P.4
  • 56
    • 0023623496 scopus 로고
    • B cell stimulatory factor 1 (IL-4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors
    • Pfeifer, J. D., McKenzie, D. T., Swain, S. L., and Dutton, R. W., B cell stimulatory factor 1 (IL-4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors, J. Exp. Med., 166, 1464, 1987.
    • (1987) J. Exp. Med. , vol.166 , pp. 1464
    • Pfeifer, J.D.1    McKenzie, D.T.2    Swain, S.L.3    Dutton, R.W.4
  • 57
    • 0023852397 scopus 로고
    • B cell stimulatory factor 1 (IL-4) enhances the development of cytotoxic T cells from Lyt-2+ resting murine T lymphocytes
    • Trenn, G., Takayama, H., Hu Li, J., and Paul, W. E., B cell stimulatory factor 1 (IL-4) enhances the development of cytotoxic T cells from Lyt-2+ resting murine T lymphocytes, J. Immunol., 140, 1101, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 1101
    • Trenn, G.1    Takayama, H.2    Hu Li, J.3    Paul, W.E.4
  • 58
    • 0023140706 scopus 로고
    • Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor
    • Widmer, M. B. and Grabstein, K. H., Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor, Nature, 326, 795, 1987.
    • (1987) Nature , vol.326 , pp. 795
    • Widmer, M.B.1    Grabstein, K.H.2
  • 59
    • 0026026307 scopus 로고
    • Interleukin-4 is a potent mitogen for capillary endothelium
    • Toi, M., Harris, A. L., and Bicknell, R., Interleukin-4 is a potent mitogen for capillary endothelium, Biochem. Biophys. Res. Commun., 174, 1287, 1991.
    • (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 1287
    • Toi, M.1    Harris, A.L.2    Bicknell, R.3
  • 60
    • 0025264318 scopus 로고
    • Effects of six different cytokines on lymphocyte adherence to microvascular endothelium and in vivo lymphocyte migration in the rat
    • Issekutz, T. B., Effects of six different cytokines on lymphocyte adherence to microvascular endothelium and in vivo lymphocyte migration in the rat, J. Immunol., 144, 2140, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 2140
    • Issekutz, T.B.1
  • 62
    • 0026031380 scopus 로고
    • Interleukin-4 induces interleukin-6 production by endothelial cells: Synergy with interferon gamma
    • Howells, G., Pham, P., Taylor, D., Foxwell, B., and Feldmann, M., Interleukin-4 induces interleukin-6 production by endothelial cells: synergy with interferon gamma, Eur. J. Immunol., 21, 97, 1991.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 97
    • Howells, G.1    Pham, P.2    Taylor, D.3    Foxwell, B.4    Feldmann, M.5
  • 63
    • 0025090541 scopus 로고
    • Disparate regulation of interleukin 8 gene expression from blood monocytes, endothelial cells, and fibroblasts by interleukin 4
    • Standiford, T. J., Strieter, R. M., Kasahara, K., and Kunkel, S. L., Disparate regulation of interleukin 8 gene expression from blood monocytes, endothelial cells, and fibroblasts by interleukin 4, Biochem. Biophys. Res. Commun., 171, 531, 1990.
    • (1990) Biochem. Biophys. Res. Commun. , vol.171 , pp. 531
    • Standiford, T.J.1    Strieter, R.M.2    Kasahara, K.3    Kunkel, S.L.4
  • 64
    • 0025336004 scopus 로고
    • IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor or IFN-gamma
    • Thornhill, M. H. and Haskard, D. O., IL-4 regulates endothelial cell activation by IL-1, tumor necrosis factor or IFN-gamma, J. Immunol., 145, 865, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 865
    • Thornhill, M.H.1    Haskard, D.O.2
  • 66
    • 0024502120 scopus 로고
    • Murine interleukin-4 displays potent anti-tumor activity in vivo
    • Tepper, R. I., Pattengale, P. K., and Leder, P., Murine interleukin-4 displays potent anti-tumor activity in vivo, Cell, 57, 503, 1989.
    • (1989) Cell , vol.57 , pp. 503
    • Tepper, R.I.1    Pattengale, P.K.2    Leder, P.3
  • 68
    • 0023272603 scopus 로고
    • B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens
    • Crawford, R. M., Finbloom, D. S., Ohara, J., Paul, W. E., and Meltzer, M. S., B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens, J. Immunol., 139, 135, 1987.
    • (1987) J. Immunol. , vol.139 , pp. 135
    • Crawford, R.M.1    Finbloom, D.S.2    Ohara, J.3    Paul, W.E.4    Meltzer, M.S.5
  • 69
    • 0023871959 scopus 로고
    • Role of IL-2, IL-4, and alpha, beta, and gamma interferon in stimulating macrophage antibody-dependent tumoricidal activity
    • Ralph, P., Nakoinz, I., and Rennick, D., Role of IL-2, IL-4, and alpha, beta, and gamma interferon in stimulating macrophage antibody-dependent tumoricidal activity, J. Exp. Med., 167, 712, 1988.
    • (1988) J. Exp. Med. , vol.167 , pp. 712
    • Ralph, P.1    Nakoinz, I.2    Rennick, D.3
  • 70
    • 0023747688 scopus 로고
    • IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures
    • Spits, H., Yssel, H., Paliard, X., Kastelein, R., Figdor, C., and de Vries, J. E., IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures, J. Immunol., 141, 29, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 29
    • Spits, H.1    Yssel, H.2    Paliard, X.3    Kastelein, R.4    Figdor, C.5    De Vries, J.E.6
  • 71
    • 0024534349 scopus 로고
    • Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFNγ
    • Littman, B. H., Dastvan, F., Frank, F., Carlson, P.L., and Sanders, K. M., Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFNγ, J. Immunol., 142, 520, 1989.
    • (1989) J. Immunol. , vol.142 , pp. 520
    • Littman, B.H.1    Dastvan, F.2    Frank, F.3    Carlson, P.L.4    Sanders, K.M.5
  • 72
    • 0023667058 scopus 로고
    • B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cell lines
    • Brown, M. A., Pierce, J. H., Watson, C. J., Falco, J., Ihle, J. N., and Paul, W. E., B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cell lines, Cell, 50, 809, 1987.
    • (1987) Cell , vol.50 , pp. 809
    • Brown, M.A.1    Pierce, J.H.2    Watson, C.J.3    Falco, J.4    Ihle, J.N.5    Paul, W.E.6
  • 73
    • 0024564031 scopus 로고
    • Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores
    • Plaut, M., Pierce, J. H., Watson, C. J., Hanley-Hyde, J., Nordon, R. P., and Paul, W. E., Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores, Nature, 339, 64, 1989.
    • (1989) Nature , vol.339 , pp. 64
    • Plaut, M.1    Pierce, J.H.2    Watson, C.J.3    Hanley-Hyde, J.4    Nordon, R.P.5    Paul, W.E.6
  • 74
    • 0029036278 scopus 로고
    • Expression of the CD40 ligand in T lymphocytes and induction of IgE isotype switching
    • Fuleihan, R., Ahern, D., and Geha, R. S., Expression of the CD40 ligand in T lymphocytes and induction of IgE isotype switching, Int. Arch. Allergy Immunol., 107, 43, 1995.
    • (1995) Int. Arch. Allergy Immunol. , vol.107 , pp. 43
    • Fuleihan, R.1    Ahern, D.2    Geha, R.S.3
  • 75
    • 0028527386 scopus 로고
    • CD40 and its ligand in the regulation of humoral immunity
    • Klaus, S., Berberich, I., Shu, G., and Clark, E. A., CD40 and its ligand in the regulation of humoral immunity, Semin. Immunol., 6, 279, 1994.
    • (1994) Semin. Immunol. , vol.6 , pp. 279
    • Klaus, S.1    Berberich, I.2    Shu, G.3    Clark, E.A.4
  • 77
    • 0023132811 scopus 로고
    • Interleukin 4 is an essential factor for in vitro clonal growth of murine connective tissue-type mast cells
    • Hamaguchi, Y., Kanakura, Y., Fujita, J., Takeda, S., Nakano, T., Tarui, S., Honjo, T., and Kitamura, Y., Interleukin 4 is an essential factor for in vitro clonal growth of murine connective tissue-type mast cells, J. Exp. Med., 165, 268, 1987.
    • (1987) J. Exp. Med. , vol.165 , pp. 268
    • Hamaguchi, Y.1    Kanakura, Y.2    Fujita, J.3    Takeda, S.4    Nakano, T.5    Tarui, S.6    Honjo, T.7    Kitamura, Y.8
  • 79
    • 0025083185 scopus 로고
    • IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice
    • Tepper, R. L., Levison, D. A., Stanger, B. Z., Campos-Torres, J., Abbas, A. K., and Leder, P., IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice, Cell, 62, 457, 1990.
    • (1990) Cell , vol.62 , pp. 457
    • Tepper, R.L.1    Levison, D.A.2    Stanger, B.Z.3    Campos-Torres, J.4    Abbas, A.K.5    Leder, P.6
  • 81
    • 0028144786 scopus 로고
    • IL-4: A key cytokine in atopy
    • Ricci, M., IL-4: a key cytokine in atopy, Clin. Exp. Allergy, 24, 801, 1994.
    • (1994) Clin. Exp. Allergy , vol.24 , pp. 801
    • Ricci, M.1
  • 82
    • 0027297244 scopus 로고
    • Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5 and IL-6 in human allergic mucosal inflammation
    • Bradding, P., Feather, I. H., Wilson, S., Bardin, P. G., Heusser, C. H., Holgate, S. T., and Howarth, P. H., Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5 and IL-6 in human allergic mucosal inflammation, J. Immunol., 151, 3853, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 3853
    • Bradding, P.1    Feather, I.H.2    Wilson, S.3    Bardin, P.G.4    Heusser, C.H.5    Holgate, S.T.6    Howarth, P.H.7
  • 83
    • 0028230946 scopus 로고
    • Linkage analysis of IL4 and other chromosomal 5q31.1 markers and total serum concentrations
    • Marsh, D. G., Neely, J. D., and Breazeale, D. R., Linkage analysis of IL4 and other chromosomal 5q31.1 markers and total serum concentrations, Science, 264, 1152, 1994.
    • (1994) Science , vol.264 , pp. 1152
    • Marsh, D.G.1    Neely, J.D.2    Breazeale, D.R.3
  • 84
    • 0028096020 scopus 로고
    • Novel fundamental approaches to intervening in IgE-mediated allergic diseases
    • de Vries, J. E., Novel fundamental approaches to intervening in IgE-mediated allergic diseases, J. Invest. Dermatol., 102, 141, 1994.
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 141
    • De Vries, J.E.1
  • 85
    • 0023946485 scopus 로고
    • IL-4-induced lymphokine-activated killer cells. Lytic activity is mediated by phenotypically distinct natural killer-like and T cell-like large granular lymphocytes
    • Peace, D. J., Kern, D. E., Schultz, K. R., Greenberg, P. D., and Cheever, M. A., IL-4-induced lymphokine-activated killer cells. Lytic activity is mediated by phenotypically distinct natural killer-like and T cell-like large granular lymphocytes, J. Immunol., 140, 3679, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 3679
    • Peace, D.J.1    Kern, D.E.2    Schultz, K.R.3    Greenberg, P.D.4    Cheever, M.A.5
  • 86
    • 0023735385 scopus 로고
    • The effects of IL-4 on human natural killer cells. A potent regulator of IL-2 activation and proliferation
    • Nagler, A., Lanier, L. L., and Phillips, J. H., The effects of IL-4 on human natural killer cells. A potent regulator of IL-2 activation and proliferation, J. Immunol., 141, 2349, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 2349
    • Nagler, A.1    Lanier, L.L.2    Phillips, J.H.3
  • 87
    • 0023575741 scopus 로고
    • Interleukin-4 (B cell stimulatory factor 1) can mediate the induction of lymphokine-activated killer cell activity directed against fresh tumor cells
    • Mule, J. J., Smith, C. A., and Rosenberg, S. A., Interleukin-4 (B cell stimulatory factor 1) can mediate the induction of lymphokine-activated killer cell activity directed against fresh tumor cells, J. Exp. Med., 166, 792, 1987.
    • (1987) J. Exp. Med. , vol.166 , pp. 792
    • Mule, J.J.1    Smith, C.A.2    Rosenberg, S.A.3
  • 89
    • 0026657391 scopus 로고
    • An eosinophil-dependent mechanism for the antitumor effect of interleukin-4
    • Tepper, R. I., Coffman, R. L., and Leder, P., An eosinophil-dependent mechanism for the antitumor effect of interleukin-4, Science, 257, 548, 1992.
    • (1992) Science , vol.257 , pp. 548
    • Tepper, R.I.1    Coffman, R.L.2    Leder, P.3
  • 90
    • 0027407938 scopus 로고
    • Mechanisms of rejection induced by tumor cell targeted gene transfer of interleukin-2, interleukin-4, interleukin-7, tumor necrosis factor and interferon gamma
    • Hock, H., Dorsch, M., Kunzendorf, U., Quin, Z., Diamanstein, T., and Blankenstein, T., Mechanisms of rejection induced by tumor cell targeted gene transfer of interleukin-2, interleukin-4, interleukin-7, tumor necrosis factor and interferon gamma, Proc. Natl. Acad. Sci. U.S.A., 90, 2774, 1993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 2774
    • Hock, H.1    Dorsch, M.2    Kunzendorf, U.3    Quin, Z.4    Diamanstein, T.5    Blankenstein, T.6
  • 91
    • 0025119692 scopus 로고
    • Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently non-immunogenic tumors and induce a tumor-specific immune memory
    • Bosco, M., Giovarelli, M., Forni, M., Modesti, A., Scarpas, S., Masuelli, L., and Forni, G., Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently non-immunogenic tumors and induce a tumor-specific immune memory, J. Immunol., 145, 3136, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 3136
    • Bosco, M.1    Giovarelli, M.2    Forni, M.3    Modesti, A.4    Scarpas, S.5    Masuelli, L.6    Forni, G.7
  • 92
    • 0024210868 scopus 로고
    • Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma
    • Kawakami, Y., Rosenberg, S. A., and Lotze, M. T., Interleukin 4 promotes the growth of tumor-infiltrating lymphocytes cytotoxic for human autologous melanoma, J. Exp. Med., 168, 2183, 1988.
    • (1988) J. Exp. Med. , vol.168 , pp. 2183
    • Kawakami, Y.1    Rosenberg, S.A.2    Lotze, M.T.3
  • 95
    • 0029146695 scopus 로고
    • Gene therapy of metastatic cancer by in vivo retroviral gene targeting
    • Hurford, P. K. J., Dranoff, G., Mulligan, R. C., and Tepper, R. I., Gene therapy of metastatic cancer by in vivo retroviral gene targeting, Nature Genet., 10, 430, 1995.
    • (1995) Nature Genet. , vol.10 , pp. 430
    • Hurford, P.K.J.1    Dranoff, G.2    Mulligan, R.C.3    Tepper, R.I.4
  • 96
    • 0027167517 scopus 로고
    • Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone
    • Louie, S. W., Rammirez, L. M., Krieg, A. M., Maliszewski, C. R., and Bishop, G. A., Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone, J. Immunol., 150, 339, 1993.
    • (1993) J. Immunol. , vol.150 , pp. 339
    • Louie, S.W.1    Rammirez, L.M.2    Krieg, A.M.3    Maliszewski, C.R.4    Bishop, G.A.5
  • 97
    • 0024247417 scopus 로고
    • Constitutive production of lymphokines by cloned murine B-cell lymphomas-CH12 B lymphoma produces interleukin-4
    • O'Garra, A., Barbis, D., Harada, N., Lee, F., and Howard, M., Constitutive production of lymphokines by cloned murine B-cell lymphomas-CH12 B lymphoma produces interleukin-4, J. Mol. Cell. Immunol., 4, 149, 1989.
    • (1989) J. Mol. Cell. Immunol. , vol.4 , pp. 149
    • O'Garra, A.1    Barbis, D.2    Harada, N.3    Lee, F.4    Howard, M.5
  • 99
    • 0023727628 scopus 로고
    • Leukemic cells from some adult T cell leukemia patients proliferate in response to IL-4
    • Uchiyama, T., Kamio, M., Kodaka, T., Fukahara, S., Amakawa, R., Uchino, H., and Araki, K., Leukemic cells from some adult T cell leukemia patients proliferate in response to IL-4, Blood, 72, 1182, 1988.
    • (1988) Blood , vol.72 , pp. 1182
    • Uchiyama, T.1    Kamio, M.2    Kodaka, T.3    Fukahara, S.4    Amakawa, R.5    Uchino, H.6    Araki, K.7
  • 100
    • 0023792281 scopus 로고
    • Leukemic cells from a CLL patient proliferated in response to both IL-2 and IL-4 without prior stimulation and produced IL-2 mRNA with stimulation
    • Umadome, H., Uchiyama, T., Onishi, R., Hori, T., Uchino, H., and Nesumi, N., Leukemic cells from a CLL patient proliferated in response to both IL-2 and IL-4 without prior stimulation and produced IL-2 mRNA with stimulation, Blood, 72, 1177, 1988.
    • (1988) Blood , vol.72 , pp. 1177
    • Umadome, H.1    Uchiyama, T.2    Onishi, R.3    Hori, T.4    Uchino, H.5    Nesumi, N.6
  • 101
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul, W. E. and Seder, R. A., Lymphocyte responses and cytokines, Cell, 76, 241, 1994.
    • (1994) Cell , vol.76 , pp. 241
    • Paul, W.E.1    Seder, R.A.2
  • 102
    • 2042462430 scopus 로고
    • Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B cell stimulatory factor-1
    • Finkelman, F. D., Katona, I. M., Urban, J. F., Snapper, C. M., Ohara, J., and Paul, W. E., Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B cell stimulatory factor-1, Proc. Natl. Acad. Sci. U.S.A., 83, 9675, 1986.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 9675
    • Finkelman, F.D.1    Katona, I.M.2    Urban, J.F.3    Snapper, C.M.4    Ohara, J.5    Paul, W.E.6
  • 103
    • 0025133974 scopus 로고
    • Cure of murine leishmaniasis with anti-interleukin-4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism
    • Sadick, M. D., Heinzel, F. P., Holaday, B. J., Pu, R. T., Dawkins, R. S., and Locksley, R. M., Cure of murine leishmaniasis with anti-interleukin-4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism, J. Exp. Med., 171, 115, 1990.
    • (1990) J. Exp. Med. , vol.171 , pp. 115
    • Sadick, M.D.1    Heinzel, F.P.2    Holaday, B.J.3    Pu, R.T.4    Dawkins, R.S.5    Locksley, R.M.6
  • 104
  • 105
    • 0027526657 scopus 로고
    • Changes in interleukin 2 and interleukin 4 production in asymptomatic, human immunodeficiency virus-seropositive individuals
    • Clerici, M., Hakim, F. T., Venzon, D. J., Blatt, S., Hendrix, C. W., Wynn, T. A., and Shearer, G. M., Changes in interleukin 2 and interleukin 4 production in asymptomatic, human immunodeficiency virus-seropositive individuals, J. Clin. Invest., 91, 759, 1993.
    • (1993) J. Clin. Invest. , vol.91 , pp. 759
    • Clerici, M.1    Hakim, F.T.2    Venzon, D.J.3    Blatt, S.4    Hendrix, C.W.5    Wynn, T.A.6    Shearer, G.M.7
  • 108
    • 0028334719 scopus 로고
    • Tolerance induction to multiple minor histoincompatible cells by activated B cells is associated with preferential activation of Th2 cells
    • Gorczynski, R. M. and Kiziroglu, F., Tolerance induction to multiple minor histoincompatible cells by activated B cells is associated with preferential activation of Th2 cells, Transplantation, 58, 51, 1994.
    • (1994) Transplantation , vol.58 , pp. 51
    • Gorczynski, R.M.1    Kiziroglu, F.2
  • 109
    • 0029145618 scopus 로고
    • Administration of intragraft interleukin-4 prolongs cardiac allograft survival in rats treated with donor-specific transfusion/ cyclosporine
    • Levy, A. E. and Alexander, J. W., Administration of intragraft interleukin-4 prolongs cardiac allograft survival in rats treated with donor-specific transfusion/ cyclosporine, Transplantation, 60, 405, 1995.
    • (1995) Transplantation , vol.60 , pp. 405
    • Levy, A.E.1    Alexander, J.W.2
  • 111
    • 0028922933 scopus 로고
    • Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance
    • Chen, N. and Field, E. H., Enhanced type 2 and diminished type 1 cytokines in neonatal tolerance, Transplantation, 59, 933, 1995.
    • (1995) Transplantation , vol.59 , pp. 933
    • Chen, N.1    Field, E.H.2
  • 112
    • 0028967385 scopus 로고
    • Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long surviving mouse heart allografts after brief CD4-monoclonal antibody therapy
    • Mottram, P. L., Han, W. R., Purcell, L. J., McKenzie, I, F., and Hancock, W. W., Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long surviving mouse heart allografts after brief CD4-monoclonal antibody therapy, Transplantation, 59, 559, 1995.
    • (1995) Transplantation , vol.59 , pp. 559
    • Mottram, P.L.1    Han, W.R.2    Purcell, L.J.3    McKenzie, I.F.4    Hancock, W.W.5
  • 113
    • 0023492716 scopus 로고
    • Murine cutaneous leishmaniasis: Susceptibility correlates with differential expansion of helper T cell subsets
    • Locksley, R. M., Heinzel, F. P., Sadick, M. D., Holaday, B. J., and Gardner, K. D., Jr., Murine cutaneous leishmaniasis: susceptibility correlates with differential expansion of helper T cell subsets, Ann. Inst. Pasteur Immunol., 138, 744, 1987.
    • (1987) Ann. Inst. Pasteur Immunol. , vol.138 , pp. 744
    • Locksley, R.M.1    Heinzel, F.P.2    Sadick, M.D.3    Holaday, B.J.4    Gardner Jr., K.D.5
  • 114
    • 0026562075 scopus 로고
    • CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly through an early, transient, Th0-like stage
    • Vella, A. T. and Pearce, E. J., CD4+ Th2 response induced by Schistosoma mansoni eggs develops rapidly through an early, transient, Th0-like stage, J. Immunol., 148, 2283, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 2283
    • Vella, A.T.1    Pearce, E.J.2
  • 115
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R. and Coffman, R. L., Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties, Annu. Rev. Immunol., 7, 145, 1989.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 117
    • 0025358166 scopus 로고
    • Evidence for compartmentalization of functional subsets of CD4+ T lymphocytes in atopic patients
    • Wierenga, E. A., Snock, M., deGroot, C., Chretien, L, Jansen, H. M., and Kapsenberg, M. L., Evidence for compartmentalization of functional subsets of CD4+ T lymphocytes in atopic patients, J. Immunol., 144, 4651, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 4651
    • Wierenga, E.A.1    Snock, M.2    DeGroot, C.3    Chretien, L.4    Jansen, H.M.5    Kapsenberg, M.L.6
  • 118
    • 0026571223 scopus 로고
    • T cell activation inducing epitopes on the house dust allergen Der p I: Proliferation and lymphokine production patterns for der p I-specific CD4+ T cell clones
    • Yssel, H., Johnson, K., Schneider, P. V., Wideman, J., Tere, A., Kastelein, R., and de Vries, J., T cell activation inducing epitopes on the house dust allergen Der p I: proliferation and lymphokine production patterns for der p I-specific CD4+ T cell clones, J. Immunol., 148, 738, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 738
    • Yssel, H.1    Johnson, K.2    Schneider, P.V.3    Wideman, J.4    Tere, A.5    Kastelein, R.6    De Vries, J.7
  • 119
    • 0023726937 scopus 로고
    • Antiproliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • Gajewski, T. F. and Fitch, F. W., Antiproliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones, J. Immunol., 140, 4245, 1988.
    • (1988) J. Immunol. , vol.140 , pp. 4245
    • Gajewski, T.F.1    Fitch, F.W.2
  • 120
    • 0025335354 scopus 로고
    • Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein Barr virus gene BCRF
    • Moore, K. W., Vieira, P., Florentine, D. F., Trounstine, M. L., Khan, T. A., and Mosmann, T. R., Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein Barr virus gene BCRF, Science, 248, 1230, 1990.
    • (1990) Science , vol.248 , pp. 1230
    • Moore, K.W.1    Vieira, P.2    Florentine, D.F.3    Trounstine, M.L.4    Khan, T.A.5    Mosmann, T.R.6
  • 121
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response in Leishmania major-infected mice
    • Chatelain, R., Varkila, K., and Coffman, R. L., IL-4 induces a Th2 response in Leishmania major-infected mice, J. Immunol., 148, 1182, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 1182
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 122
    • 0028980812 scopus 로고
    • Differential production of interferon-y and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo
    • Ferrick, D. A., Schrenzel, M. D., Mulvania, T., Hsieh, B., Ferlin, W. G., and Lepper, H., Differential production of interferon-y and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo, Nature, 373, 255, 1995.
    • (1995) Nature , vol.373 , pp. 255
    • Ferrick, D.A.1    Schrenzel, M.D.2    Mulvania, T.3    Hsieh, B.4    Ferlin, W.G.5    Lepper, H.6
  • 123
    • 0021739871 scopus 로고
    • Frequent coexpression of cytolytic activity and lymphokine production among human T lymphocytes: Production of B cell growth factor and IL-2 by T8+ and T4+ cytolytic clones
    • Mingari, M. C., Moretta, A., Maggi, E., Pantaleo, G., Gerosa, F., Romagnani, S., and Moretta, L., Frequent coexpression of cytolytic activity and lymphokine production among human T lymphocytes: production of B cell growth factor and IL-2 by T8+ and T4+ cytolytic clones, Eur. J. Immunol., 14, 1066, 1984.
    • (1984) Eur. J. Immunol. , vol.14 , pp. 1066
    • Mingari, M.C.1    Moretta, A.2    Maggi, E.3    Pantaleo, G.4    Gerosa, F.5    Romagnani, S.6    Moretta, L.7
  • 126
    • 0025360024 scopus 로고
    • Alloreactive murine T cell clones secrete the Th1 pattern of cytokines
    • Fong, T. A. T. and Mossman, T. R., Alloreactive murine T cell clones secrete the Th1 pattern of cytokines, J. Immunol., 144, 1744, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 1744
    • Fong, T.A.T.1    Mossman, T.R.2
  • 128
    • 0028960040 scopus 로고
    • Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines
    • Sad, S., Marcotte, R., and Mosmann, T. R., Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines, Immunity, 2, 271, 1995.
    • (1995) Immunity , vol.2 , pp. 271
    • Sad, S.1    Marcotte, R.2    Mosmann, T.R.3
  • 129
    • 0026708993 scopus 로고
    • Cytokine production by mature and immature CD4-CD8- T cells. αβ-T cell receptor + CD4-CD8- T cells produce IL-4
    • Zlotnick, A., Godfrey, D. I., Fischer, M., and Suda, T., Cytokine production by mature and immature CD4-CD8- T cells. αβ-T cell receptor + CD4-CD8- T cells produce IL-4, J. Immunol., 149, 1211, 1992.
    • (1992) J. Immunol. , vol.149 , pp. 1211
    • Zlotnick, A.1    Godfrey, D.I.2    Fischer, M.3    Suda, T.4
  • 131
    • 0028177589 scopus 로고
    • CD4+, NK1.1+ T cells promptly produce interleukin-4 in response to in vivo challenge with anti-CD3
    • Yoshimoto, T. and Paul, W. E., CD4+, NK1.1+ T cells promptly produce interleukin-4 in response to in vivo challenge with anti-CD3, J. Exp. Med., 179, 1285, 1994.
    • (1994) J. Exp. Med. , vol.179 , pp. 1285
    • Yoshimoto, T.1    Paul, W.E.2
  • 132
    • 0025266887 scopus 로고
    • Anti-CD3 antibodies induce T cells from unprimed animals to secrete IL-4 both in vivo and in vitro
    • Flamand, V., Abramowicz, D., Goldman, M., Biernaux, C., Huez, G., Urbain, J., Moser, M., and Leo, O., Anti-CD3 antibodies induce T cells from unprimed animals to secrete IL-4 both in vivo and in vitro, J. Immunol., 144, 2875, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 2875
    • Flamand, V.1    Abramowicz, D.2    Goldman, M.3    Biernaux, C.4    Huez, G.5    Urbain, J.6    Moser, M.7    Leo, O.8
  • 133
    • 0025094642 scopus 로고
    • Anti-CD3 antibody induces rapid expression of cytokine genes in vivo
    • Scott, D. E., Gause, W. C., Finkleman, F. D., and Steinberg, A. D., Anti-CD3 antibody induces rapid expression of cytokine genes in vivo, J. Immunol., 145, 2183, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 2183
    • Scott, D.E.1    Gause, W.C.2    Finkleman, F.D.3    Steinberg, A.D.4
  • 134
    • 0027511242 scopus 로고
    • NK1.1 + CD4+ CD8- thymocytes with specific lymphokine secretion
    • Arase, H., Arase, N., Nakagaw, K., Good, R. A., and Onoe, K., NK1.1 + CD4+ CD8- thymocytes with specific lymphokine secretion, Eur. J. Immunol., 23, 307, 1993.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 307
    • Arase, H.1    Arase, N.2    Nakagaw, K.3    Good, R.A.4    Onoe, K.5
  • 135
    • 0029562066 scopus 로고
    • Role of NK1.1+ T cells in a Th2 response and in immunoglobulin E production
    • Yoshimoto, T., Bendelac, A., Watson, C., Hu-Li, J., and Paul, W. E., Role of NK1.1+ T cells in a Th2 response and in immunoglobulin E production, Science, 270, 1845, 1995.
    • (1995) Science , vol.270 , pp. 1845
    • Yoshimoto, T.1    Bendelac, A.2    Watson, C.3    Hu-Li, J.4    Paul, W.E.5
  • 136
    • 0023625207 scopus 로고
    • Mechanisms and mediators in urticaria
    • Czarnetzki, B. M., Mechanisms and mediators in urticaria, Semin. Dermatol., 6, 272, 1987.
    • (1987) Semin. Dermatol. , vol.6 , pp. 272
    • Czarnetzki, B.M.1
  • 138
    • 0024566954 scopus 로고
    • Production of the haemopoietic growth factors GM-CSF and interleukin 3 by mast cells in response to IgE receptor-mediated activation
    • Wodnar-Filipowicz, A., Heusser, C. H., and Moroni, C., Production of the haemopoietic growth factors GM-CSF and interleukin 3 by mast cells in response to IgE receptor-mediated activation, Nature, 339, 150, 1989.
    • (1989) Nature , vol.339 , pp. 150
    • Wodnar-Filipowicz, A.1    Heusser, C.H.2    Moroni, C.3
  • 139
    • 0025242472 scopus 로고
    • Mast cells as a source of multifunctional cytokines
    • Gordon, J. R., Burd, P. R., and Galli, S. J., Mast cells as a source of multifunctional cytokines, Immunol. Today, 11, 458, 1991.
    • (1991) Immunol. Today , vol.11 , pp. 458
    • Gordon, J.R.1    Burd, P.R.2    Galli, S.J.3
  • 140
    • 0025880963 scopus 로고
    • Interleukin-4 production by FcεR+ cells
    • Paul, W. E., Interleukin-4 production by FcεR+ cells, Skin Pharmacol., 4, 8, 1991.
    • (1991) Skin Pharmacol. , vol.4 , pp. 8
    • Paul, W.E.1
  • 141
    • 0028278699 scopus 로고
    • Secretion of IL-4 from basophils: The relationship between IL-4 mRNA and protein in resting and stimulated basophils
    • MacGlashan, D. W., White, J. M., Huang, S. K., Ono, S. J., Schroeder, J., and Lichtenstein, L. M., Secretion of IL-4 from basophils: the relationship between IL-4 mRNA and protein in resting and stimulated basophils, J. Immunol., 152, 3006, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 3006
    • MacGlashan, D.W.1    White, J.M.2    Huang, S.K.3    Ono, S.J.4    Schroeder, J.5    Lichtenstein, L.M.6
  • 147
    • 0025014866 scopus 로고
    • Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines
    • Ben-Sasson, S. Z., LeGros, G., Conrad, D. H., Finkelman, F. D., and Paul, W. E., Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines, Proc. Natl. Acad. Sci. U.S.A., 87, 1421, 1990.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 1421
    • Ben-Sasson, S.Z.1    LeGros, G.2    Conrad, D.H.3    Finkelman, F.D.4    Paul, W.E.5
  • 149
    • 0027464843 scopus 로고
    • Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation
    • Brunner, T., Heusser, C. H., and Dahinden, C. A., Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation, J. Exp. Med., 177, 605, 1993.
    • (1993) J. Exp. Med. , vol.177 , pp. 605
    • Brunner, T.1    Heusser, C.H.2    Dahinden, C.A.3
  • 154
    • 0017087542 scopus 로고
    • The late phase of immediate wheal and flare skin reaction: Its dependence on IgE antibodies
    • Solley, G. O., Gleich, G. J., Jordon, R. E., and Shroeter, A. L., The late phase of immediate wheal and flare skin reaction: its dependence on IgE antibodies, J. Clin. Invest., 58, 408, 1976.
    • (1976) J. Clin. Invest. , vol.58 , pp. 408
    • Solley, G.O.1    Gleich, G.J.2    Jordon, R.E.3    Shroeter, A.L.4
  • 155
    • 0015292546 scopus 로고
    • Basophilic leukocytes in allergic contact dermatitis
    • Dvorak, H. F. and Mihm, M. C., Basophilic leukocytes in allergic contact dermatitis, J. Exp. Med., 135, 235, 1972.
    • (1972) J. Exp. Med. , vol.135 , pp. 235
    • Dvorak, H.F.1    Mihm, M.C.2
  • 157
    • 0017578426 scopus 로고
    • Extracellular release of peroxidase from eosinophils by interaction with immune complexes
    • Takenaka, T., Okuda, M., Kawabori, S., and Kubo, K., Extracellular release of peroxidase from eosinophils by interaction with immune complexes, Clin. Exp. Immunol., 28, 56, 1977.
    • (1977) Clin. Exp. Immunol. , vol.28 , pp. 56
    • Takenaka, T.1    Okuda, M.2    Kawabori, S.3    Kubo, K.4
  • 158
    • 0021949555 scopus 로고
    • Extracellular release of rat eosinophil peroxidase (EPO). I. Role of anaphylactic immunoglobulins
    • Khalife, J., Capron, M., Grzych, J. M., Bazin, H., and Capron, A., Extracellular release of rat eosinophil peroxidase (EPO). I. Role of anaphylactic immunoglobulins, J. Immunol., 134, 1968, 1985.
    • (1985) J. Immunol. , vol.134 , pp. 1968
    • Khalife, J.1    Capron, M.2    Grzych, J.M.3    Bazin, H.4    Capron, A.5
  • 160
    • 0024470222 scopus 로고
    • Detection of individual interleukin 4 and γ Interferon producing murine spleen cells after activation with T cell mitogens
    • Sander, B., Cardell, S., Heremans, H., and Andersson, U., Detection of individual interleukin 4 and γ Interferon producing murine spleen cells after activation with T cell mitogens, Scand. J. Immunol., 30, 315, 1989.
    • (1989) Scand. J. Immunol. , vol.30 , pp. 315
    • Sander, B.1    Cardell, S.2    Heremans, H.3    Andersson, U.4
  • 161
    • 0007465909 scopus 로고
    • Analysis by in situ hybridization of cells expressing mRNA for interleukin 4 in the developing thymus and in peripheral lymphocytes from mice
    • Sideras, P. K., Funa, K., Zalcberg-Quintana, I., Xanthopoulos, K. G., Kisielow, P., and Palacios, R., Analysis by in situ hybridization of cells expressing mRNA for interleukin 4 in the developing thymus and in peripheral lymphocytes from mice, Proc. Natl. Acad. Sci. U.S.A., 82, 218, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 218
    • Sideras, P.K.1    Funa, K.2    Zalcberg-Quintana, I.3    Xanthopoulos, K.G.4    Kisielow, P.5    Palacios, R.6
  • 163
    • 0029032046 scopus 로고
    • Molecular mechanisms underlying functional T cell unresponsiveness
    • Mueller, D. L. and Jenkins, M. K., Molecular mechanisms underlying functional T cell unresponsiveness, Curr. Opin. Immunol., 7, 375, 1995.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 375
    • Mueller, D.L.1    Jenkins, M.K.2
  • 165
    • 0025791981 scopus 로고
    • Structure-function relationships in the mast cell high affinity receptor for IgE. Role of the cytoplasmic domains and of the beta subunit
    • Alber, G., Miller, L., Jelsema, C. L., Varin-Blank, N., and Metzger, H., Structure-function relationships in the mast cell high affinity receptor for IgE. Role of the cytoplasmic domains and of the beta subunit, J. Biol. Chem., 266, 22613, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22613
    • Alber, G.1    Miller, L.2    Jelsema, C.L.3    Varin-Blank, N.4    Metzger, H.5
  • 166
    • 0027998862 scopus 로고
    • Differ ential control of the tyrosine kinases lyn and syk by the two signaling chains of the high affinity immunoglobulin E receptor
    • Jouvin, M. H., Adamczewsk, M., Numerof, R., Letourneur, O., Valle, A., and Kinet, J. P., Differ ential control of the tyrosine kinases lyn and syk by the two signaling chains of the high affinity immunoglobulin E receptor, J. Biol. Chem., 269, 5918, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 5918
    • Jouvin, M.H.1    Adamczewsk, M.2    Numerof, R.3    Letourneur, O.4    Valle, A.5    Kinet, J.P.6
  • 167
    • 1842315667 scopus 로고
    • Transmembrane signalling in P815 mastocytoma cells by transfected IgE receptors
    • Miller, L., Alber, G., Varin-Blank, N., Ludowyke, R., and Metzger, H., Transmembrane signalling in P815 mastocytoma cells by transfected IgE receptors, J. Biol. Chem., 205, 7819, 1988.
    • (1988) J. Biol. Chem. , vol.205 , pp. 7819
    • Miller, L.1    Alber, G.2    Varin-Blank, N.3    Ludowyke, R.4    Metzger, H.5
  • 168
    • 0025887061 scopus 로고
    • Relationship of IgE receptor topography to secretion in RBL-2H3 mast cells
    • Seagrave, J. C., Pfeiffer, J. R., Wofsy, C., and Oliver, J. O., Relationship of IgE receptor topography to secretion in RBL-2H3 mast cells, J. Cell. Phys., 148, 139, 1991.
    • (1991) J. Cell. Phys. , vol.148 , pp. 139
    • Seagrave, J.C.1    Pfeiffer, J.R.2    Wofsy, C.3    Oliver, J.O.4
  • 169
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth, M., Antigen receptor tail clue, Nature, 338, 383, 1989.
    • (1989) Nature , vol.338 , pp. 383
    • Reth, M.1
  • 170
    • 0025610845 scopus 로고
    • IL-10, a novel growth cofactor for mature and immature T cells
    • MacNeil, I. A., Suda, T., Moore, K. W., Mosmann, T. R., and Zlotnik, A., IL-10, a novel growth cofactor for mature and immature T cells, J. Immunol., 145, 4167, 1990.
    • (1990) J. Immunol. , vol.145 , pp. 4167
    • MacNeil, I.A.1    Suda, T.2    Moore, K.W.3    Mosmann, T.R.4    Zlotnik, A.5
  • 172
    • 0026601947 scopus 로고
    • Engagement of the high affinity IgE receptor activates src protein-related tyrosine kinases
    • Eiseman, E. and Bolen, J. B., Engagement of the high affinity IgE receptor activates src protein-related tyrosine kinases, Nature, 355, 78, 1992.
    • (1992) Nature , vol.355 , pp. 78
    • Eiseman, E.1    Bolen, J.B.2
  • 173
    • 0025156165 scopus 로고
    • CD4, CD8 and the TCR-CD3 complex, a novel class of protein-tyrosine kinase receptor
    • Rudd, C. E., CD4, CD8 and the TCR-CD3 complex, a novel class of protein-tyrosine kinase receptor, Immunol. Today, 11, 400, 1990.
    • (1990) Immunol. Today , vol.11 , pp. 400
    • Rudd, C.E.1
  • 174
    • 0026705903 scopus 로고
    • Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
    • Strauss, D. B. and Weiss, A., Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor, Cell, 70, 585, 1992.
    • (1992) Cell , vol.70 , pp. 585
    • Strauss, D.B.1    Weiss, A.2
  • 176
    • 0026612655 scopus 로고
    • The gamma-zeta dimers of Fc receptors as connectors to signal transduction
    • Kinet, J. P., The gamma-zeta dimers of Fc receptors as connectors to signal transduction, Curr. Opin. Immunol., 4, 43, 1992.
    • (1992) Curr. Opin. Immunol. , vol.4 , pp. 43
    • Kinet, J.P.1
  • 177
    • 0026454253 scopus 로고
    • Phosphorylation/dephosphorylation of high affinity IgE receptors: A mechanism for coupling/uncoupling a large signaling complex
    • Paolini, R., Numeroff, R., and Kinet, J. P., Phosphorylation/dephosphorylation of high affinity IgE receptors: a mechanism for coupling/uncoupling a large signaling complex, Proc. Natl. Acad. Sci. U.S.A., 89, 10733, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10733
    • Paolini, R.1    Numeroff, R.2    Kinet, J.P.3
  • 178
    • 0026483786 scopus 로고
    • ZAP-70 a 70kd protein-tyrosine kinase that associates with the TCR ζ chain
    • Chan, A. C., Iwshima, M., Turck, C. W., and Weiss, A., ZAP-70 a 70kd protein-tyrosine kinase that associates with the TCR ζ chain, Cell, 71, 649, 1992.
    • (1992) Cell , vol.71 , pp. 649
    • Chan, A.C.1    Iwshima, M.2    Turck, C.W.3    Weiss, A.4
  • 179
    • 0025942245 scopus 로고
    • The ζ-chain is associated with a tyrosine kinase and upon T cell antigen receptor stimulation associates with ZAP-70 a 70 kilodalton phosphoprotein
    • Chan, A. C., Irving, B. A., Fraser, J. D., and Weiss, A. D., The ζ-chain is associated with a tyrosine kinase and upon T cell antigen receptor stimulation associates with ZAP-70 a 70 kilodalton phosphoprotein, Proc. Natl. Acad. Sci. U.S.A., 88, 9166, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 9166
    • Chan, A.C.1    Irving, B.A.2    Fraser, J.D.3    Weiss, A.D.4
  • 180
    • 0028209548 scopus 로고
    • Sequential interactions of the TCR with two distinct tyrosine kinases
    • Iwashima, M., Irving, B. A., Van Oers, N. S., Chan, A. C., and Weiss, A., Sequential interactions of the TCR with two distinct tyrosine kinases, Science, 263, 1136, 1994.
    • (1994) Science , vol.263 , pp. 1136
    • Iwashima, M.1    Irving, B.A.2    Van Oers, N.S.3    Chan, A.C.4    Weiss, A.5
  • 181
    • 0028072499 scopus 로고
    • Role of the protein tyrosine kinase, syk, in signal transduction in mast cells: Inhibition of FcεRI mediated signaling by the syk selective inhibitor piceatannol
    • Oliver, J. M., Burg, D. L., Deanin, G. G., McLaughlin, J. L., and Geahlen, R. L., Role of the protein tyrosine kinase, syk, in signal transduction in mast cells: inhibition of FcεRI mediated signaling by the syk selective inhibitor piceatannol, J. Biol. Chem., 269, 29697, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29697
    • Oliver, J.M.1    Burg, D.L.2    Deanin, G.G.3    McLaughlin, J.L.4    Geahlen, R.L.5
  • 182
    • 0027433055 scopus 로고
    • Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation
    • Benhamou, M., Ryba, N. J., Kihara, N., Nishkata, H., and Siraganian, R. P., Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation, J. Biol. Chem., 268, 23318, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 23318
    • Benhamou, M.1    Ryba, N.J.2    Kihara, N.3    Nishkata, H.4    Siraganian, R.P.5
  • 183
    • 0026611481 scopus 로고
    • Fcε-RI-mediated tyrosine phosphorylation and activation of the 72 kd protein tyrosine kinase PTK72 in RBL-2H3 rat tumor mast cells
    • Hutchcroft, J. E., Geahlen, R. L., Deanin, G. G., and Oliver, J. O., Fcε-RI-mediated tyrosine phosphorylation and activation of the 72 kd protein tyrosine kinase PTK72 in RBL-2H3 rat tumor mast cells, Proc. Natl. Acad. Sci. U.S.A., 89, 9107, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 9107
    • Hutchcroft, J.E.1    Geahlen, R.L.2    Deanin, G.G.3    Oliver, J.O.4
  • 184
    • 0026612253 scopus 로고
    • Fcε-RI-mediated tyrosine phosphorylation of multiple proteins including phospholipase C gamma 1 and the receptor beta/gamma2 complex in RBL-2H3 cells
    • Li, W., Deanin, G. G., Margolis, B., Schlessinger, J., and Oliver, J. M., Fcε-RI-mediated tyrosine phosphorylation of multiple proteins including phospholipase C gamma 1 and the receptor beta/gamma2 complex in RBL-2H3 cells, Mol. Cell. Biol., 12, 3176, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3176
    • Li, W.1    Deanin, G.G.2    Margolis, B.3    Schlessinger, J.4    Oliver, J.M.5
  • 185
    • 0021917674 scopus 로고
    • Transmembrane signaling by the T cell antigen receptor: Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores
    • Imboden, J. B. and Stobo, J. D., Transmembrane signaling by the T cell antigen receptor: perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores, J. Exp. Med., 161, 446, 1985.
    • (1985) J. Exp. Med. , vol.161 , pp. 446
    • Imboden, J.B.1    Stobo, J.D.2
  • 186
    • 0026600298 scopus 로고
    • Phospholipase C gamma 1 is translocated to the membrane of rat basophilic leukemia cells in response to aggregation of IgE receptors
    • Atkinson, T. P., Kaliner, M. A., and Hohman, R. J., Phospholipase C gamma 1 is translocated to the membrane of rat basophilic leukemia cells in response to aggregation of IgE receptors, J. Immunol., 148, 2194, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 2194
    • Atkinson, T.P.1    Kaliner, M.A.2    Hohman, R.J.3
  • 188
    • 0026575932 scopus 로고
    • The mechanism of action of cyclosporin A and FK506
    • Schreiber, S. L. and Crabtree, G. R., The mechanism of action of cyclosporin A and FK506, Immunol. Today, 13, 136, 1992.
    • (1992) Immunol. Today , vol.13 , pp. 136
    • Schreiber, S.L.1    Crabtree, G.R.2
  • 189
    • 0027518679 scopus 로고
    • Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex
    • Northrop, J. P., Ullman, K. S., and Crabtree, G. R., Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex, J. Biol. Chem., 268, 2917, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 2917
    • Northrop, J.P.1    Ullman, K.S.2    Crabtree, G.R.3
  • 190
    • 0028300431 scopus 로고
    • NF-ATp: A transcription factor required for the coordinate induction of several cytokine genes
    • Rao, A., NF-ATp: a transcription factor required for the coordinate induction of several cytokine genes, Immunol. Today, 15, 274, 1994.
    • (1994) Immunol. Today , vol.15 , pp. 274
    • Rao, A.1
  • 191
    • 0023690127 scopus 로고
    • Translocation of protein kinase C in rat basophilic leukemia cells induced by phorbol ester or aggregation of IgE receptors
    • White, K. N. and Metzger, H., Translocation of protein kinase C in rat basophilic leukemia cells induced by phorbol ester or aggregation of IgE receptors, J. Immunol., 141, 942, 1988.
    • (1988) J. Immunol. , vol.141 , pp. 942
    • White, K.N.1    Metzger, H.2
  • 192
    • 0027207287 scopus 로고
    • Tyrosine kinase stimulated guanine nucleotide exchange activity of Vav in T cell activation
    • Gulbins, E., Coggeshall, K. M., Baier, G., Katsav, S., Burn, P., and Altman, A., Tyrosine kinase stimulated guanine nucleotide exchange activity of Vav in T cell activation, Science, 260, 822, 1993.
    • (1993) Science , vol.260 , pp. 822
    • Gulbins, E.1    Coggeshall, K.M.2    Baier, G.3    Katsav, S.4    Burn, P.5    Altman, A.6
  • 193
    • 0026535589 scopus 로고
    • Tyrosine phosphorylation of the Vav proto-oncogene product: A potential transcriptional regulator with SH2 and SH3 domains
    • Margolis, B., Hu, P., Katzav, S., Li, W., Olive, R. J. M., Ullrich, A., Weiss, A., and Schlessinger, J., Tyrosine phosphorylation of the Vav proto-oncogene product: a potential transcriptional regulator with SH2 and SH3 domains, Nature, 356, 71, 1992.
    • (1992) Nature , vol.356 , pp. 71
    • Margolis, B.1    Hu, P.2    Katzav, S.3    Li, W.4    Olive, R.J.M.5    Ullrich, A.6    Weiss, A.7    Schlessinger, J.8
  • 194
    • 0026338533 scopus 로고
    • CD45: A prototype for transmembrane protein tyrosine phosphatases
    • Trowbridge, I. S., CD45: a prototype for transmembrane protein tyrosine phosphatases, J. Biol. Chem., 266, 23517, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23517
    • Trowbridge, I.S.1
  • 195
    • 0024346410 scopus 로고
    • A monoclonal antibody to murine CD45R distinguishes T cell populations that produce different cytokines
    • Bottomly, K., Luqman, M., Greenbaum, L., Carding, S., West, J., Pasqualini, T., and Murphy, D. B., A monoclonal antibody to murine CD45R distinguishes T cell populations that produce different cytokines, Eur. J. Immunol., 19, 617, 1989.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 617
    • Bottomly, K.1    Luqman, M.2    Greenbaum, L.3    Carding, S.4    West, J.5    Pasqualini, T.6    Murphy, D.B.7
  • 196
    • 0024343604 scopus 로고
    • CD45-protein tyrosine phosphatase cross-linking inhibits T cell receptor CD3-mediated activation in human T cells
    • Kiener, P. A. and Mittler, R. S., CD45-protein tyrosine phosphatase cross-linking inhibits T cell receptor CD3-mediated activation in human T cells, J. Immunol., 143, 23, 1989.
    • (1989) J. Immunol. , vol.143 , pp. 23
    • Kiener, P.A.1    Mittler, R.S.2
  • 197
    • 0009013817 scopus 로고
    • CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells
    • Ledbetter, J. A., Tonks, N. K., Fischer, E. H., and Clark, E. A., CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells, Proc. Natl. Acad. Sci. U.S.A., 85, 8628, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 8628
    • Ledbetter, J.A.1    Tonks, N.K.2    Fischer, E.H.3    Clark, E.A.4
  • 198
    • 0025297050 scopus 로고
    • Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidylinositol pathway
    • Koretzky, G. A., Picus, J., Thomas, M. L., and Weiss, A., Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidylinositol pathway, Nature, 346, 66, 1990.
    • (1990) Nature , vol.346 , pp. 66
    • Koretzky, G.A.1    Picus, J.2    Thomas, M.L.3    Weiss, A.4
  • 199
    • 0026011310 scopus 로고
    • Tyrosine phosphatase CD45 is required for both T cell antigen receptor and CD2 mediated activation of a protein tyrosine kinase and interleukin-2 production
    • Koretzky, G. A., Picus, J., Schultz, T., and Weiss, A., Tyrosine phosphatase CD45 is required for both T cell antigen receptor and CD2 mediated activation of a protein tyrosine kinase and interleukin-2 production, Proc. Natl. Acad. Sci. U.S.A., 88, 2037, 1991.
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 2037
    • Koretzky, G.A.1    Picus, J.2    Schultz, T.3    Weiss, A.4
  • 200
    • 0022559078 scopus 로고
    • Tyr 527 is phosphorylated in pp60c-src: Implication for regulation
    • Cooper, J. A., Gould, K. A., Cartwright, C. A., and Hunter, T., Tyr 527 is phosphorylated in pp60c-src: implication for regulation, Science, 231, 1431, 1986.
    • (1986) Science , vol.231 , pp. 1431
    • Cooper, J.A.1    Gould, K.A.2    Cartwright, C.A.3    Hunter, T.4
  • 201
    • 0026657173 scopus 로고
    • Evidence for two distinct phosphorylation pathways activated by high affinity immunoglobulin E receptors
    • Adamczewski, M., Paolini, R., and Kinet, J. P., Evidence for two distinct phosphorylation pathways activated by high affinity immunoglobulin E receptors, J. Biol. Chem., 267, 18126, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18126
    • Adamczewski, M.1    Paolini, R.2    Kinet, J.P.3
  • 202
    • 0028914242 scopus 로고
    • Regulation by CD-45 of the activation-induced phosphorylation of high affinity IgE receptor β and γ chains
    • Adamczewski, M., Numerof, R., and Kinet, J. P., Regulation by CD-45 of the activation-induced phosphorylation of high affinity IgE receptor β and γ chains, J. Immunol., 154, 3047, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 3047
    • Adamczewski, M.1    Numerof, R.2    Kinet, J.P.3
  • 204
    • 0027192884 scopus 로고
    • Antigen presenting cell-derived co-stimulatory signals can selectively regulate IL-2 and IL-4 production from a Th0 cell hybridoma
    • Fox, B. S., Antigen presenting cell-derived co-stimulatory signals can selectively regulate IL-2 and IL-4 production from a Th0 cell hybridoma, Int. Immunol., 5, 323, 1993.
    • (1993) Int. Immunol. , vol.5 , pp. 323
    • Fox, B.S.1
  • 205
    • 0029073090 scopus 로고
    • Distinct roles for costimulatory ligands B7-1 and B7-2 in T helper cell differentiation
    • Thompson, C. B., Distinct roles for costimulatory ligands B7-1 and B7-2 in T helper cell differentiation, Cell, 81, 979, 1995.
    • (1995) Cell , vol.81 , pp. 979
    • Thompson, C.B.1
  • 206
    • 0028979466 scopus 로고
    • New perspectives of CD28-B7 mediated T cell costimulation
    • Bluestone, J., New perspectives of CD28-B7 mediated T cell costimulation, Immunity, 2, 555, 1995.
    • (1995) Immunity , vol.2 , pp. 555
    • Bluestone, J.1
  • 207
    • 0029073050 scopus 로고
    • B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
    • Freeman, G. J., Boussiotis, V. A., Anumanthan, A., Bernstein, G. M., Ke, X.-Y., Rennert, P. D., Gray, G. S., Gribben, J. G., and Nadler, L. M., B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4, Immunity, 2, 523, 1995.
    • (1995) Immunity , vol.2 , pp. 523
    • Freeman, G.J.1    Boussiotis, V.A.2    Anumanthan, A.3    Bernstein, G.M.4    Ke, X.-Y.5    Rennert, P.D.6    Gray, G.S.7    Gribben, J.G.8    Nadler, L.M.9
  • 208
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/ Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo, V. K., Das, M. P., Brown, J. A., Ranger, A. M., Zamvil, S. S., Sobel, R. A., Weiner, H. L., Nabavi, N., and Glimcher, L. H., B7-1 and B7-2 costimulatory molecules activate differentially the Th1/ Th2 developmental pathways: application to autoimmune disease therapy, Cell, 80, 707, 1995.
    • (1995) Cell , vol.80 , pp. 707
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6    Weiner, H.L.7    Nabavi, N.8    Glimcher, L.H.9
  • 209
    • 0024802919 scopus 로고
    • Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4
    • Daynes, R. A. and Araneo, B. S., Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4, Eur. J. Immunol., 19, 2319, 1989.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2319
    • Daynes, R.A.1    Araneo, B.S.2
  • 210
    • 0025667152 scopus 로고
    • cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells
    • Novak, T. J. and Rothenberg, E. V., cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells, Proc. Natl. Acad. Sci., U.S.A., 87, 9353, 1990.
    • (1990) Proc. Natl. Acad. Sci., U.S.A. , vol.87 , pp. 9353
    • Novak, T.J.1    Rothenberg, E.V.2
  • 211
    • 0025338731 scopus 로고
    • Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: Role of cAMP in T cell proliferation
    • Munoz, E., Zubiaga, A. M., Merrow, M., Sauter, N. P., and Huber, B. T., Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation, J. Exp. Med., 172, 95, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 95
    • Munoz, E.1    Zubiaga, A.M.2    Merrow, M.3    Sauter, N.P.4    Huber, B.T.5
  • 212
    • 0025924175 scopus 로고
    • Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines
    • Betz, M. and Fox, B. S., Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines, J. Immunol., 146, 108, 1991.
    • (1991) J. Immunol. , vol.146 , pp. 108
    • Betz, M.1    Fox, B.S.2
  • 213
    • 0025288654 scopus 로고
    • Evidence implicating utilization of different T cell receptor-associated signaling pathways by Th1 and Th2 clones
    • Gajewski, T. F., Schell, S. R., and Fitch, F. W., Evidence implicating utilization of different T cell receptor-associated signaling pathways by Th1 and Th2 clones, J. Immunol., 144, 4110, 1990.
    • (1990) J. Immunol. , vol.144 , pp. 4110
    • Gajewski, T.F.1    Schell, S.R.2    Fitch, F.W.3
  • 214
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • Mitchell, P. J. and Tijan, R., Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins, Science, 245, 371, 1989.
    • (1989) Science , vol.245 , pp. 371
    • Mitchell, P.J.1    Tijan, R.2
  • 215
    • 0028903049 scopus 로고
    • Combinatorial regular tion of transcription I: General aspects of transcriptional control
    • Ernest, P. and Smale, S. T., Combinatorial regular tion of transcription I: general aspects of transcriptional control, Immunity, 2, 311, 1995.
    • (1995) Immunity , vol.2 , pp. 311
    • Ernest, P.1    Smale, S.T.2
  • 216
    • 0027305687 scopus 로고
    • Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: Roles for NF-Y and NF-ATc
    • Szabo, S. J., Gold, J. S., Murphy, T. L., and Murphy, K. M., Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc, Mol. Cell. Biol., 13, 4793, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4793
    • Szabo, S.J.1    Gold, J.S.2    Murphy, T.L.3    Murphy, K.M.4
  • 219
    • 0029008237 scopus 로고
    • Characterization of the constitutive and inducible components of a T cell activation responsive element
    • Tara, D., Weiss, D. L., and Brown, M. A., Characterization of the constitutive and inducible components of a T cell activation responsive element, J. Immunol., 154, 4592, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 4592
    • Tara, D.1    Weiss, D.L.2    Brown, M.A.3
  • 220
    • 0025931765 scopus 로고
    • Characterization of the mouse granulocyte-macrophage colony stimulating factor (GM-CSF) gene promoter: Nuclear factors that interact with an element shared by three lymphokine genes-those for GM-CSF, interleukin-4 (IL-4) and IL-5
    • Miyatake, S., Shlomai, J., Ariai, K.-I., and Arai, N., Characterization of the mouse granulocyte-macrophage colony stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes-those for GM-CSF, interleukin-4 (IL-4) and IL-5, Mol. Cell. Biol., 11, 5894, 1991.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5894
    • Miyatake, S.1    Shlomai, J.2    Ariai, K.-I.3    Arai, N.4
  • 221
    • 0027251928 scopus 로고
    • Transcription of the interleukin 4 gene is regulated by multiple promoter elements
    • Todd, M. D., Grusby, M. J., Lederer, J. A., Lacy, E., Lichtman, A. H., and Glimcher, L. H., Transcription of the interleukin 4 gene is regulated by multiple promoter elements, J. Exp. Med., 177, 1663, 1993.
    • (1993) J. Exp. Med. , vol.177 , pp. 1663
    • Todd, M.D.1    Grusby, M.J.2    Lederer, J.A.3    Lacy, E.4    Lichtman, A.H.5    Glimcher, L.H.6
  • 222
    • 0029023580 scopus 로고
    • The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors
    • Hodge, M. R., Rooney, J. W., and Glimcher, L. H., The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors, J. Immunol., 154, 6397, 1995.
    • (1995) J. Immunol. , vol.154 , pp. 6397
    • Hodge, M.R.1    Rooney, J.W.2    Glimcher, L.H.3
  • 223
    • 0026552626 scopus 로고
    • An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T cell activation signals
    • Abe, E., Malefyt, R., Matsuda, I., Arai, K., and Arai, N., An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T cell activation signals, Proc. Natl. Acad. Sci. U.S.A., 89, 2864, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 2864
    • Abe, E.1    Malefyt, R.2    Matsuda, I.3    Arai, K.4    Arai, N.5
  • 224
    • 0028064905 scopus 로고
    • Activation of the interleukin-4 gene is controlled by the unique calcineurin-dependent transcriptional factor NF(P)
    • Kubo, M., Kincaid, R. L., and Ransom, J. T., Activation of the interleukin-4 gene is controlled by the unique calcineurin-dependent transcriptional factor NF(P), J. Biol. Chem., 269, 19441, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19441
    • Kubo, M.1    Kincaid, R.L.2    Ransom, J.T.3
  • 225
    • 0028355876 scopus 로고
    • Characterization of NF(P), the nuclear factor that interacts with the regulatory P sequence (5́CGAAAATTTCC-3́) of the human interleukin-4 gene: Relationship to NF-kB and NF-AT
    • Matsuda, I., Masuda, E. S., Tsuboi, A., Behnam, S., Arai, N., and Arai, K.-I., Characterization of NF(P), the nuclear factor that interacts with the regulatory P sequence (5́CGAAAATTTCC-3́) of the human interleukin-4 gene: relationship to NF-kB and NF-AT, Biochem. Biophys. Res. Comm., 199, 439, 1994.
    • (1994) Biochem. Biophys. Res. Comm. , vol.199 , pp. 439
    • Matsuda, I.1    Masuda, E.S.2    Tsuboi, A.3    Behnam, S.4    Arai, N.5    Arai, K.-I.6
  • 226
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
    • Rooney, J. W., Hoey, T., and Glimcher, L. H., Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene, Immunity, 2, 473, 1995.
    • (1995) Immunity , vol.2 , pp. 473
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 227
    • 0028157768 scopus 로고
    • A common factor regulates both ThI and Th2-specific cytokine gene expression
    • Rooney, J. W., Hodge, M. R., McCaffrey, P. G., Rao, A., and Glimcher, L. H., A common factor regulates both ThI and Th2-specific cytokine gene expression, EMBO J., 13, 625, 1994.
    • (1994) EMBO J. , vol.13 , pp. 625
    • Rooney, J.W.1    Hodge, M.R.2    McCaffrey, P.G.3    Rao, A.4    Glimcher, L.H.5
  • 228
    • 0023821516 scopus 로고
    • Identification of a putative regulator of early T cell activation genes
    • Shaw, J.-P., Utz, P. J., Durand, D. B., Toole, J. J., Emmel, E. A., and Crabtree, G. R., Identification of a putative regulator of early T cell activation genes, Science, 241, 202, 1988.
    • (1988) Science , vol.241 , pp. 202
    • Shaw, J.-P.1    Utz, P.J.2    Durand, D.B.3    Toole, J.J.4    Emmel, E.A.5    Crabtree, G.R.6
  • 229
    • 0027339327 scopus 로고
    • NF-ATp, a T lymphocyte DNA binding protein that is a target for calcineurin and immunosuppressive drugs
    • McCaffrey, P. G., Perrino, B. A., Soderling, T. R., and Rao, A., NF-ATp, a T lymphocyte DNA binding protein that is a target for calcineurin and immunosuppressive drugs, J. Biol. Chem., 268, 3747, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 3747
    • McCaffrey, P.G.1    Perrino, B.A.2    Soderling, T.R.3    Rao, A.4
  • 230
    • 0028361589 scopus 로고
    • NF-AT components define a family of transcription factors targeted in T cell activation
    • Northrop, J. P., Ho, S. N., Timmerman, L. A., Nolan, G. P., Admon, A., and Crabtree, G. R., NF-AT components define a family of transcription factors targeted in T cell activation. Nature, 369, 497, 1994.
    • (1994) Nature , vol.369 , pp. 497
    • Northrop, J.P.1    Ho, S.N.2    Timmerman, L.A.3    Nolan, G.P.4    Admon, A.5    Crabtree, G.R.6
  • 232
    • 0029125831 scopus 로고
    • NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity
    • Ho, S. N., Thomas, D. J., Timmerman, L. A., Li, X., Francke, U., and Crabtree, G. R., NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity, J. Biol. Chem., 270, 19898, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19898
    • Ho, S.N.1    Thomas, D.J.2    Timmerman, L.A.3    Li, X.4    Francke, U.5    Crabtree, G.R.6
  • 233
    • 0029053852 scopus 로고
    • Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
    • Hoey, T., Sun, Y.-L., Williamson, K., and Xu, X., Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins, Immunity, 2, 461, 1995.
    • (1995) Immunity , vol.2 , pp. 461
    • Hoey, T.1    Sun, Y.-L.2    Williamson, K.3    Xu, X.4
  • 234
    • 0028930843 scopus 로고
    • NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus
    • Masuda, E. S., Naito, Y., Tokumitsu, H., Campbell, D., Saito, F., Hannum, C., Arai, K. I., and Arai, N., NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus, Mol. Cell. Biol., 15, 2697, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2697
    • Masuda, E.S.1    Naito, Y.2    Tokumitsu, H.3    Campbell, D.4    Saito, F.5    Hannum, C.6    Arai, K.I.7    Arai, N.8
  • 235
    • 0028180103 scopus 로고
    • The Ca2+/calmodulin activated phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene
    • Kubo, M., Kincaid, R. L., Webb, D. R., and Ransom, J. T., The Ca2+/calmodulin activated phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene, Int. Immunol., 6, 179, 1994.
    • (1994) Int. Immunol. , vol.6 , pp. 179
    • Kubo, M.1    Kincaid, R.L.2    Webb, D.R.3    Ransom, J.T.4
  • 236
    • 0027985435 scopus 로고
    • Role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression
    • Li-Weber, M., Davydov, I. V., Krafft, H., and Krammer, P. H., Role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression, J. Immunol., 153, 4122, 1994.
    • (1994) J. Immunol. , vol.153 , pp. 4122
    • Li-Weber, M.1    Davydov, I.V.2    Krafft, H.3    Krammer, P.H.4
  • 238
    • 0028889432 scopus 로고
    • Nuclear factor-IL6 activates the human IL-4 promoter in T cells
    • Davydov, I. V., Krammer, P. H., and Li-Weber, M., Nuclear factor-IL6 activates the human IL-4 promoter in T cells, J. Immunol., 155, 5273, 1995.
    • (1995) J. Immunol. , vol.155 , pp. 5273
    • Davydov, I.V.1    Krammer, P.H.2    Li-Weber, M.3
  • 239
    • 0029098998 scopus 로고
    • Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-1 enhancer element of the human interleukin-4 promoter
    • Davydov, I. V., Bohmann, D., Krammer, P. H., and Li-Weber, M., Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-1 enhancer element of the human interleukin-4 promoter, Gene, 161, 1995.
    • (1995) Gene , pp. 161
    • Davydov, I.V.1    Bohmann, D.2    Krammer, P.H.3    Li-Weber, M.4
  • 240
    • 0025311121 scopus 로고
    • Transcriptional repression in eukaryotes
    • Renkawitz, R., Transcriptional repression in eukaryotes, Trends Genet., 6, 192, 1990.
    • (1990) Trends Genet. , vol.6 , pp. 192
    • Renkawitz, R.1
  • 241
    • 0024412752 scopus 로고
    • Transcriptional repression of eukaryotic promoters
    • Levine, M. and Manley, J. L., Transcriptional repression of eukaryotic promoters, Cell, 59, 405, 1989.
    • (1989) Cell , vol.59 , pp. 405
    • Levine, M.1    Manley, J.L.2
  • 242
    • 0026510627 scopus 로고
    • T cell specific negative regulation of transcription of the human cytokine IL-4
    • Li-Weber, M., Eder, A., Krafft-Czepa, H., and Krammer, P. H., T cell specific negative regulation of transcription of the human cytokine IL-4, J. Immunol., 148, 1913, 1992.
    • (1992) J. Immunol. , vol.148 , pp. 1913
    • Li-Weber, M.1    Eder, A.2    Krafft-Czepa, H.3    Krammer, P.H.4
  • 243
    • 0024853833 scopus 로고
    • The same 50 kDa cellular protein binds to the negative regulatory elements of interieukin 2 receptor 2-chain gene and the human immunodeficiency virus type 1 long terminal repeat
    • Smith, M. R. and Greene, W. C., The same 50 kDa cellular protein binds to the negative regulatory elements of interieukin 2 receptor 2-chain gene and the human immunodeficiency virus type 1 long terminal repeat, Proc. Natl. Acad. Sci. U.S.A., 86, 8526, 1989.
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 8526
    • Smith, M.R.1    Greene, W.C.2
  • 244
    • 0025336820 scopus 로고
    • Modular structure of chicken lysozyme silencer. Involvement of usual thyroid hormone receptor binding site
    • Baniamad, A., Steiner, C., Kohne, A. C., and Renkawitz, R., Modular structure of chicken lysozyme silencer. Involvement of usual thyroid hormone receptor binding site, Cell, 61, 505, 1990.
    • (1990) Cell , vol.61 , pp. 505
    • Baniamad, A.1    Steiner, C.2    Kohne, A.C.3    Renkawitz, R.4
  • 245
    • 0027275095 scopus 로고
    • A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer
    • Li-Weber, M., Karfft, H., and Krammer, P. H., A novel enhancer element in the human IL-4 promoter is suppressed by a position-independent silencer, J. Immunol., 151, 1371, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 1371
    • Li-Weber, M.1    Karfft, H.2    Krammer, P.H.3
  • 247
    • 0027303114 scopus 로고
    • The B7 adhesion molecule is expressed on activated human T cells: Functional involvement in T-T cell interactions
    • Wyss-Coray, T., Mauri-Hellweg, D., Bauman, K., Bettens, F., Grunow, R., and Pichler, W. J., The B7 adhesion molecule is expressed on activated human T cells: functional involvement in T-T cell interactions, Eur. J. Immunol., 23, 2157, 1993.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2157
    • Wyss-Coray, T.1    Mauri-Hellweg, D.2    Bauman, K.3    Bettens, F.4    Grunow, R.5    Pichler, W.J.6
  • 248
    • 0027199019 scopus 로고
    • Interleukin 7 specifically induces B7/BB1 antigen on human cord blood and peripheral blood T cells and T cell clones
    • Yssel, H., Schneider, P. V., and Lanier, L. L., Interleukin 7 specifically induces B7/BB1 antigen on human cord blood and peripheral blood T cells and T cell clones, Int. Immunol., 5, 753, 1993.
    • (1993) Int. Immunol. , vol.5 , pp. 753
    • Yssel, H.1    Schneider, P.V.2    Lanier, L.L.3
  • 249
  • 251
    • 0027141283 scopus 로고
    • Current understanding of IL-4 gene regulation in T cells
    • Murphy, K. M., Murphy, T. L., Gold, J. S., and Szabo, S. J., Current understanding of IL-4 gene regulation in T cells, Res. Immunol., 144, 575, 1993.
    • (1993) Res. Immunol. , vol.144 , pp. 575
    • Murphy, K.M.1    Murphy, T.L.2    Gold, J.S.3    Szabo, S.J.4
  • 252
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • Le Gros, G., Ben-Sasson, S. Z., Seder, R., Finkleman, F. D., and Paul, W. E., Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells, J. Exp. Med., 172, 921, 1990.
    • (1990) J. Exp. Med. , vol.172 , pp. 921
    • Le Gros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkleman, F.D.4    Paul, W.E.5
  • 254
    • 0028500569 scopus 로고
    • Cytokines and growth factors signal through tyrosine phosphorylation of a family of related transcription factors
    • Rothman, P., Kreider, Azam, M. B., Levy, D., Wegenka, U., Eilers, A., Decker, T., Horn, F., Ihle, J., and Schindler, C., Cytokines and growth factors signal through tyrosine phosphorylation of a family of related transcription factors, Immunity, 1, 457, 1994.
    • (1994) Immunity , vol.1 , pp. 457
    • Rothman, P.1    Kreider2    Azam, M.B.3    Levy, D.4    Wegenka, U.5    Eilers, A.6    Decker, T.7    Horn, F.8    Ihle, J.9    Schindler, C.10
  • 256
    • 0023899769 scopus 로고
    • Nuclease hypersensitive sites in chromatin
    • Gross, D. S. and Garrard, W. T., Nuclease hypersensitive sites in chromatin, Annu. Rev. Biochem., 57, 159, 1988.
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 159
    • Gross, D.S.1    Garrard, W.T.2
  • 257
    • 0027285756 scopus 로고
    • Regulated expression of germline antigen receptor genes in mast cell lines from the murine embryo
    • Siden, E., Regulated expression of germline antigen receptor genes in mast cell lines from the murine embryo, J. Immunol., 150, 4427, 1993.
    • (1993) J. Immunol. , vol.150 , pp. 4427
    • Siden, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.