-
1
-
-
0029856557
-
Three distinct signalling responses by murine fibroblasts to genotoxic stress [see comments]
-
Liu Z.G., Baskaran R., Lea-Chou E.T., Wood L.D., Chen Y., Karin M., Wang J.Y. Three distinct signalling responses by murine fibroblasts to genotoxic stress [see comments]. Nature. 384:1996;273-276.
-
(1996)
Nature
, vol.384
, pp. 273-276
-
-
Liu, Z.G.1
Baskaran, R.2
Lea-Chou, E.T.3
Wood, L.D.4
Chen, Y.5
Karin, M.6
Wang, J.Y.7
-
2
-
-
0029849620
-
Cancer cell cycles
-
Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
3
-
-
2642656403
-
P53 gene mutation: Software and database
-
Beroud C., Soussi T. p53 gene mutation: software and database. Nucleic Acids Res. 26:1998;200-204.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 200-204
-
-
Beroud, C.1
Soussi, T.2
-
4
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
5
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko L.J., Prives C. p53: puzzle and paradigm. Genes Dev. 10:1996;1054-1072.
-
(1996)
Genes Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
6
-
-
0030930366
-
A model for p53-induced apoptosis [see comments]
-
Polyak K., Xia Y., Zweier J.L., Kinzler K.W., Vogelstein B. A model for p53-induced apoptosis [see comments]. Nature. 389:1997;300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
7
-
-
0033105716
-
Abnormal expression or mutation of TP53 and HPV in vulvar cancer
-
Ngan H.Y., Cheung A.N., Liu S.S., Yip P.S., Tsao S.W. Abnormal expression or mutation of TP53 and HPV in vulvar cancer. Eur. J. Cancer. 35:1999;481-484.
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 481-484
-
-
Ngan, H.Y.1
Cheung, A.N.2
Liu, S.S.3
Yip, P.S.4
Tsao, S.W.5
-
9
-
-
0032506460
-
P53 polymorphism and risk of cervical cancer
-
Hildesheim A., Schiffman M., Brinton L.A., Fraumeni J.F. Jr., Herrero R., Bratti M.C., Schwartz P., Mortel R., Barnes W., Greenberg M., McGowan L., Scott D.R., Martin M., Herrera J.E., Carrington M. p53 polymorphism and risk of cervical cancer. Nature. 396:1998;531-532.
-
(1998)
Nature
, vol.396
, pp. 531-532
-
-
Hildesheim, A.1
Schiffman, M.2
Brinton, L.A.3
Fraumeni, J.F.4
Herrero, R.5
Bratti, M.C.6
Schwartz, P.7
Mortel, R.8
Barnes, W.9
Greenberg, M.10
McGowan, L.11
Scott, D.R.12
Martin, M.13
Herrera, J.E.14
Carrington, M.15
-
10
-
-
0031435944
-
DNA damage induces phosphorylation of the amino terminus of p53
-
Siliciano J.D., Canman C.E., Taya Y., Sakaguchi K., Appella E., Kastan M.B. DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev. 11:1997;3471-3481.
-
(1997)
Genes Dev.
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
11
-
-
0032427628
-
The role of ATM in DNA damage responses and cancer
-
Canman C.E., Lim D.S. The role of ATM in DNA damage responses and cancer. Oncogene. 17:1998;3301-3308.
-
(1998)
Oncogene
, vol.17
, pp. 3301-3308
-
-
Canman, C.E.1
Lim, D.S.2
-
12
-
-
0033566329
-
Somatic ATM mutations indicate a pathogenic role of ATM of B-cell chronic lymphocytic leukemia
-
Schaffner C., Stilgenbauer S., Rappold G.A., Dohner H., Lichter P. Somatic ATM mutations indicate a pathogenic role of ATM of B-cell chronic lymphocytic leukemia. Blood. 94:1999;748-753.
-
(1999)
Blood
, vol.94
, pp. 748-753
-
-
Schaffner, C.1
Stilgenbauer, S.2
Rappold, G.A.3
Dohner, H.4
Lichter, P.5
-
13
-
-
0032525111
-
Inactivation of the ATM gene in T-cell prolymphocytic leukemias
-
Stoppa-Lyonnet D., Soulier J., Lauge A., Dastot H., Garand R., Sigaux F., Stern M.H. Inactivation of the ATM gene in T-cell prolymphocytic leukemias. Blood. 91:1998;3920-3926.
-
(1998)
Blood
, vol.91
, pp. 3920-3926
-
-
Stoppa-Lyonnet, D.1
Soulier, J.2
Lauge, A.3
Dastot, H.4
Garand, R.5
Sigaux, F.6
Stern, M.H.7
-
14
-
-
0030800922
-
MDM2: Keeping p53 under control
-
Piette J., Neel H., Marechal V. MDM2: keeping p53 under control. Oncogene. 15:1997;1001-1010.
-
(1997)
Oncogene
, vol.15
, pp. 1001-1010
-
-
Piette, J.1
Neel, H.2
Marechal, V.3
-
15
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
Prives C. Signaling to p53: breaking the MDM2-p53 circuit. Cell. 95:1998;5-8.
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
16
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S.Y., Ikeda M., Taya Y., Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell. 91:1997;325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
17
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by MDM2
-
Unger T., Juven-Gershon T., Moallem E., Berger M., Vogt Sionov R., Lozano G., Oren M., Haupt Y. Critical role for Ser20 of human p53 in the negative regulation of p53 by MDM2. EMBO J. 18:1999;1805-1814.
-
(1999)
EMBO J.
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Vogt Sionov, R.5
Lozano, G.6
Oren, M.7
Haupt, Y.8
-
18
-
-
0030881590
-
Differential regulation of the p21/WAF-1 and MDM2 genes after high-dose UV irradiation: P53-dependent and p53-independent regulation of the MDM2 gene
-
Wu L., Levine A.J. Differential regulation of the p21/WAF-1 and MDM2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the MDM2 gene. Mol. Med. 3:1997;441-451.
-
(1997)
Mol. Med.
, vol.3
, pp. 441-451
-
-
Wu, L.1
Levine, A.J.2
-
19
-
-
0030689782
-
The p53 targets MDM2 and Fas are not required as mediators of apoptosis in vivo
-
Reinke V., Lozano G. The p53 targets MDM2 and Fas are not required as mediators of apoptosis in vivo. Oncogene. 15:1997;1527-1534.
-
(1997)
Oncogene
, vol.15
, pp. 1527-1534
-
-
Reinke, V.1
Lozano, G.2
-
21
-
-
0032518917
-
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
-
Roth J., Dobbelstein M., Freedman D.A., Shenk T., Levine A.J. Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J. 17:1998;554-564.
-
(1998)
EMBO J.
, vol.17
, pp. 554-564
-
-
Roth, J.1
Dobbelstein, M.2
Freedman, D.A.3
Shenk, T.4
Levine, A.J.5
-
22
-
-
0030905284
-
MDM2 promotes the rapid degradation of p53
-
Haupt Y., Maya R., Kazaz A., Oren M. MDM2 promotes the rapid degradation of p53. Nature. 387:1997;296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
24
-
-
0031724593
-
Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
-
Freedman D.A., Levine A.J. Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6. Mol. Cell. Biol. 18:1998;7288-7293.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7288-7293
-
-
Freedman, D.A.1
Levine, A.J.2
-
25
-
-
0032980646
-
Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53
-
Tao W., Levine A.J. Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc. Natl. Acad. Sci. U.S.A. 96:1999;3077-3080.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3077-3080
-
-
Tao, W.1
Levine, A.J.2
-
26
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R., Tanaka H., Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420:1997;25-27.
-
(1997)
FEBS Lett.
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
27
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain [comment]
-
Kussie P.H., Gorina S., Marechal V., Elenbaas B., Moreau J., Levine A.J., Pavletich N.P. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain [comment]. Science. 274:1996;948-953.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
28
-
-
0033020147
-
Regulation of p53 function and stability by phosphorylation
-
Ashcroft M., Kubbutat M.H., Vousden K.H. Regulation of p53 function and stability by phosphorylation. Mol. Cell. Biol. 19:1999;1751-1758.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1751-1758
-
-
Ashcroft, M.1
Kubbutat, M.H.2
Vousden, K.H.3
-
29
-
-
0033522143
-
DNA damage induced p53 stabilization: No indication for an involvement of p53 phosphorylation
-
Blattner C., Tobiasch E., Litfen M., Rahmsdorf H.J., Herrlich P. DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation. Oncogene. 18:1999;1723-1732.
-
(1999)
Oncogene
, vol.18
, pp. 1723-1732
-
-
Blattner, C.1
Tobiasch, E.2
Litfen, M.3
Rahmsdorf, H.J.4
Herrlich, P.5
-
30
-
-
0030665146
-
MDM-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53
-
Mayo L.D., Turchi J.J., Berberich S.J. MDM-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53. Cancer Res. 57:1997;5013-5016.
-
(1997)
Cancer Res.
, vol.57
, pp. 5013-5016
-
-
Mayo, L.D.1
Turchi, J.J.2
Berberich, S.J.3
-
31
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz J., Schreiber-Agus N., Liegeois N.J., Silverman A., Alland L., Chin L., Potes J., Chen K., Orlow I., Lee H.W., Cordon-Cardo C., DePinho R.A. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell. 92:1998;713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
Depinho, R.A.12
-
32
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang Y., Xiong Y., Yarbrough W.G. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 92:1998;725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
33
-
-
0031985007
-
Mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway
-
Chang Y.C., Lee Y.S., Tejima T., Tanaka K., Omura S., Heintz N.H., Mitsui Y., Magae J. mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway. Cell Growth Differ. 9:1998;79-84.
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 79-84
-
-
Chang, Y.C.1
Lee, Y.S.2
Tejima, T.3
Tanaka, K.4
Omura, S.5
Heintz, N.H.6
Mitsui, Y.7
Magae, J.8
-
34
-
-
0033521621
-
Association of p19(ARF) with MDM2 inhibits ubiquitin ligase activity of MDM2 for tumor suppressor p53
-
Honda R., Yasuda H. Association of p19(ARF) with MDM2 inhibits ubiquitin ligase activity of MDM2 for tumor suppressor p53. EMBO J. 18:1999;22-27.
-
(1999)
EMBO J.
, vol.18
, pp. 22-27
-
-
Honda, R.1
Yasuda, H.2
-
35
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott F.J., Bates S., James M.C., McConnell B.B., Starborg M., Brookes S., Palmero I., Ryan K., Hara E., Vousden K.H., Peters G. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17:1998;5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
36
-
-
0033605576
-
C-Abl neutralizes the inhibitory effect of MDM2 on p53
-
Sionov R.V., Moallem E., Berger M., Kazaz A., Gerlitz O., Ben-Neriah Y., Oren M., Haupt Y. c-Abl neutralizes the inhibitory effect of MDM2 on p53. J. Biol. Chem. 274:1999;8371-8374.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8371-8374
-
-
Sionov, R.V.1
Moallem, E.2
Berger, M.3
Kazaz, A.4
Gerlitz, O.5
Ben-Neriah, Y.6
Oren, M.7
Haupt, Y.8
-
38
-
-
0030957746
-
Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases
-
Erhardt P., Tomaselli K.J., Cooper G.M. Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases. J. Biol. Chem. 272:1997;15049-15052.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15049-15052
-
-
Erhardt, P.1
Tomaselli, K.J.2
Cooper, G.M.3
-
39
-
-
0030955170
-
Proteolytic cleavage of the MDM2 oncoprotein during apoptosis
-
Chen L., Marechal V., Moreau J., Levine A.J., Chen J. Proteolytic cleavage of the MDM2 oncoprotein during apoptosis. J. Biol. Chem. 272:1997;22966-22973.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22966-22973
-
-
Chen, L.1
Marechal, V.2
Moreau, J.3
Levine, A.J.4
Chen, J.5
-
40
-
-
0032548105
-
A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells
-
Pochampally R., Fodera B., Chen L., Shao W., Levine E.A., Chen J. A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells. Oncogene. 17:1998;2629-2636.
-
(1998)
Oncogene
, vol.17
, pp. 2629-2636
-
-
Pochampally, R.1
Fodera, B.2
Chen, L.3
Shao, W.4
Levine, E.A.5
Chen, J.6
-
41
-
-
0033591433
-
Activation of an MDM2-specific caspase by p53 in the absence of apoptosis
-
Pochampally R., Fodera B., Chen L., Lu W., Chen J. Activation of an MDM2-specific caspase by p53 in the absence of apoptosis. J. Biol. Chem. 274:1999;15271-15277.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15271-15277
-
-
Pochampally, R.1
Fodera, B.2
Chen, L.3
Lu, W.4
Chen, J.5
-
42
-
-
0033051322
-
MDM2 interacts with MDMX through their RING finger domains
-
Tanimura S., Ohtsuka S., Mitsui K., Shirouzu K., Yoshimura A., Ohtsubo M. MDM2 interacts with MDMX through their RING finger domains. FEBS Lett. 447:1999;5-9.
-
(1999)
FEBS Lett.
, vol.447
, pp. 5-9
-
-
Tanimura, S.1
Ohtsuka, S.2
Mitsui, K.3
Shirouzu, K.4
Yoshimura, A.5
Ohtsubo, M.6
-
43
-
-
10144259344
-
MDMX: A novel p53-binding protein with some functional properties of MDM2
-
Shvarts A., Steegenga W.T., Riteco N., van Laar T., Dekker P., Bazuine M., van Ham R.C., van der Houven van Oordt W., Hateboer G., van der Eb A.J., Jochemsen A.G. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 15:1996;5349-5357.
-
(1996)
EMBO J.
, vol.15
, pp. 5349-5357
-
-
Shvarts, A.1
Steegenga, W.T.2
Riteco, N.3
Van Laar, T.4
Dekker, P.5
Bazuine, M.6
Van Ham, R.C.7
Van Der Houven Van Oordt, W.8
Hateboer, G.9
Van Der Eb, A.J.10
Jochemsen, A.G.11
-
44
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman C.E., Lim D.S., Cimprich K.A., Taya Y., Tamai K., Sakaguchi K., Appella E., Kastan M.B., Siliciano J.D. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science. 281:1998;1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
45
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts R.S., Brumbaugh K.M., Williams J.M., Sarkaria J.N., Cliby W.A., Shieh S.Y., Taya Y., Prives C., Abraham R.T. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev. 13:1999;152-157.
-
(1999)
Genes Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
46
-
-
0029941651
-
P53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts
-
Huang L.C., Clarkin K.C., Wahl G.M. p53-dependent cell cycle arrests are preserved in DNA-activated protein kinase-deficient mouse fibroblasts. Cancer Res. 56:1996;2940-2944.
-
(1996)
Cancer Res.
, vol.56
, pp. 2940-2944
-
-
Huang, L.C.1
Clarkin, K.C.2
Wahl, G.M.3
-
47
-
-
0031025079
-
DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage
-
Rathmell W.K., Kaufmann W.K., Hurt J.C., Byrd L.L., Chu G. DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Res. 57:1997;68-74.
-
(1997)
Cancer Res.
, vol.57
, pp. 68-74
-
-
Rathmell, W.K.1
Kaufmann, W.K.2
Hurt, J.C.3
Byrd, L.L.4
Chu, G.5
-
48
-
-
0033532174
-
The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase
-
Kachnic L.A., Wu B., Wunsch H., Mekeel K.L., DeFrank J.S., Tang W., Powell S.N. The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase. J. Biol. Chem. 274:1999;13111-13117.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13111-13117
-
-
Kachnic, L.A.1
Wu, B.2
Wunsch, H.3
Mekeel, K.L.4
Defrank, J.S.5
Tang, W.6
Powell, S.N.7
-
49
-
-
0032514485
-
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
-
Woo R.A., McLure K.G., Lees-Miller S.P., Rancourt D.E., Lee P.W. DNA-dependent protein kinase acts upstream of p53 in response to DNA damage. Nature. 394:1998;700-704.
-
(1998)
Nature
, vol.394
, pp. 700-704
-
-
Woo, R.A.1
McLure, K.G.2
Lees-Miller, S.P.3
Rancourt, D.E.4
Lee, P.W.5
-
50
-
-
17444370101
-
Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells
-
Araki R., Fukumura R., Fujimori A., Taya Y., Shiloh Y., Kurimasa A., Burma S., Li G.C., Chen D.J., Sato K., Hoki Y., Tatsumi K., Abe M. Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells. Cancer Res. 59:1999;3543-3546.
-
(1999)
Cancer Res.
, vol.59
, pp. 3543-3546
-
-
Araki, R.1
Fukumura, R.2
Fujimori, A.3
Taya, Y.4
Shiloh, Y.5
Kurimasa, A.6
Burma, S.7
Li, G.C.8
Chen, D.J.9
Sato, K.10
Hoki, Y.11
Tatsumi, K.12
Abe, M.13
-
51
-
-
0030693181
-
JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases
-
Hu M.C., Qiu W.R., Wang Y.P. JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases. Oncogene. 15:1997;2277-2287.
-
(1997)
Oncogene
, vol.15
, pp. 2277-2287
-
-
Hu, M.C.1
Qiu, W.R.2
Wang, Y.P.3
-
52
-
-
0032478331
-
Stabilization and activation of p53 are regulated independently by different phosphorylation events
-
Chernov M.V., Ramana C.V., Adler V.V., Stark G.R. Stabilization and activation of p53 are regulated independently by different phosphorylation events. Proc. Natl. Acad. Sci. U.S.A. 95:1998;2284-2289.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 2284-2289
-
-
Chernov, M.V.1
Ramana, C.V.2
Adler, V.V.3
Stark, G.R.4
-
53
-
-
0032530486
-
DNA damage activates p53 through a phosphorylation-acetylation cascade
-
Sakaguchi K., Herrera J.E., Saito S., Miki T., Bustin M., Vassilev A., Anderson C.W., Appella E. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 12:1998;2831-2841.
-
(1998)
Genes Dev.
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustin, M.5
Vassilev, A.6
Anderson, C.W.7
Appella, E.8
-
54
-
-
0032484128
-
Phosphorylation of p53 serine 15 increases interaction with CBP
-
Lambert P.F., Kashanchi F., Radonovich M.F., Shiekhattar R., Brady J.N. Phosphorylation of p53 serine 15 increases interaction with CBP. J. Biol. Chem. 273:1998;33048-33053.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33048-33053
-
-
Lambert, P.F.1
Kashanchi, F.2
Radonovich, M.F.3
Shiekhattar, R.4
Brady, J.N.5
-
55
-
-
0032127947
-
Suppression of the p300-dependent MDM2 negative-feedback loop induces the p53 apoptotic function
-
Thomas A., White E. Suppression of the p300-dependent MDM2 negative-feedback loop induces the p53 apoptotic function. Genes Dev. 12:1998;1975-1985.
-
(1998)
Genes Dev.
, vol.12
, pp. 1975-1985
-
-
Thomas, A.1
White, E.2
-
56
-
-
0032539816
-
Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation
-
Kapoor M., Lozano G. Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation. Proc. Natl. Acad. Sci. U.S.A. 95:1998;2834-2837.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 2834-2837
-
-
Kapoor, M.1
Lozano, G.2
-
57
-
-
0032572792
-
DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site
-
Blaydes J.P., Hupp T.R. DNA damage triggers DRB-resistant phosphorylation of human p53 at the CK2 site. Oncogene. 17:1998;1045-1052.
-
(1998)
Oncogene
, vol.17
, pp. 1045-1052
-
-
Blaydes, J.P.1
Hupp, T.R.2
-
58
-
-
0030610565
-
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro
-
Lu H., Fisher R.P., Bailey P., Levine A.J. The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Mol. Cell. Biol. 17:1997;5923-5934.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5923-5934
-
-
Lu, H.1
Fisher, R.P.2
Bailey, P.3
Levine, A.J.4
-
59
-
-
0029969418
-
P53 is linked directly to homologous recombination processes via Rad51/Reca protein interaction
-
Sturzbecher H.W., Donzelmann B., Henning W., Knippschild U., Buchhop S. p53 is linked directly to homologous recombination processes via Rad51/Reca protein interaction. EMBO J. 15:1996;1992-2002.
-
(1996)
EMBO J.
, vol.15
, pp. 1992-2002
-
-
Sturzbecher, H.W.1
Donzelmann, B.2
Henning, W.3
Knippschild, U.4
Buchhop, S.5
-
60
-
-
0030883593
-
Interaction of p53 with the human Rad51 protein
-
Buchhop S., Gibson M.K., Wang X.W., Wagner P., Sturzbecher H.W., Harris C.C. Interaction of p53 with the human Rad51 protein. Nucleic Acids Res. 25:1997;3868-3874.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3868-3874
-
-
Buchhop, S.1
Gibson, M.K.2
Wang, X.W.3
Wagner, P.4
Sturzbecher, H.W.5
Harris, C.C.6
-
62
-
-
0032473879
-
BRCA1 physically associates with p53 and stimulates its transcriptional activity
-
Zhang H., Somasundaram K., Peng Y., Tian H., Zhang H., Bi D., Weber B.L., El-Deiry W.S. BRCA1 physically associates with p53 and stimulates its transcriptional activity. Oncogene. 16:1998;1713-1721.
-
(1998)
Oncogene
, vol.16
, pp. 1713-1721
-
-
Zhang, H.1
Somasundaram, K.2
Peng, Y.3
Tian, H.4
Zhang, H.5
Bi, D.6
Weber, B.L.7
El-Deiry, W.S.8
-
63
-
-
0030900605
-
Identification of redox/repair protein Ref-1 as a potent activator of p53
-
Jayaraman L., Murthy K.G., Zhu C., Curran T., Xanthoudakis S., Prives C. Identification of redox/repair protein Ref-1 as a potent activator of p53. Genes Dev. 11:1997;558-570.
-
(1997)
Genes Dev.
, vol.11
, pp. 558-570
-
-
Jayaraman, L.1
Murthy, K.G.2
Zhu, C.3
Curran, T.4
Xanthoudakis, S.5
Prives, C.6
-
64
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F., Dutriaux A., Lengauer C., Waldman T., Zhou S., Brown J.P., Sedivy J.M., Kinzler K.W., Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science. 282:1998;1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
65
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking H., Lengauer C., Polyak K., He T.C., Zhang L., Thiagalingam S., Kinzler K.W., Vogelstein B. 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol. Cell. 1:1997;3-11.
-
(1997)
Mol. Cell
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
Thiagalingam, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
67
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
-
Attardi L.D., Lowe S.W., Brugarolas J., Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J. 15:1996;3693-3701.
-
(1996)
EMBO J.
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
68
-
-
0032568037
-
Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis
-
Canman C.E., Kastan M.B. Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis. Oncogene. 16:1998;957-966.
-
(1998)
Oncogene
, vol.16
, pp. 957-966
-
-
Canman, C.E.1
Kastan, M.B.2
-
69
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas M.S., Alarcon R.M., Yoshida H., Giaccia A.J., Hakem R., Mak T.W., Lowe S.W. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science. 284:1999;156-159.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
Lowe, S.W.7
-
70
-
-
0032160407
-
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors
-
Pan H., Yin C., Dyson N.J., Harlow E., Yamasaki L., Van Dyke T. Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors. Mol. Cell. 2:1998;283-292.
-
(1998)
Mol. Cell
, vol.2
, pp. 283-292
-
-
Pan, H.1
Yin, C.2
Dyson, N.J.3
Harlow, E.4
Yamasaki, L.5
Van Dyke, T.6
-
71
-
-
0029958381
-
Reactive oxygen species are downstream mediators of p53-dependent apoptosis
-
Johnson T.M., Yu Z.X., Ferrans V.J., Lowenstein R.A., Finkel T. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc. Natl. Acad. Sci. U.S.A. 93:1996;11848-11852.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 11848-11852
-
-
Johnson, T.M.1
Yu, Z.X.2
Ferrans, V.J.3
Lowenstein, R.A.4
Finkel, T.5
-
72
-
-
0032541325
-
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
-
Venot C., Maratrat M., Dureuil C., Conseiller E., Bracco L., Debussche L. The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J. 17:1998;4668-4679.
-
(1998)
EMBO J.
, vol.17
, pp. 4668-4679
-
-
Venot, C.1
Maratrat, M.2
Dureuil, C.3
Conseiller, E.4
Bracco, L.5
Debussche, L.6
-
73
-
-
0033597221
-
Transcriptional activation of the human glutathione peroxidase promoter by p53
-
Tan M., Li S., Swaroop M., Guan K., Oberley L.W., Sun Y. Transcriptional activation of the human glutathione peroxidase promoter by p53. J. Biol. Chem. 274:1999;12061-12066.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12061-12066
-
-
Tan, M.1
Li, S.2
Swaroop, M.3
Guan, K.4
Oberley, L.W.5
Sun, Y.6
-
74
-
-
0031887249
-
Regulation of the p85/p110 phosphatidylinositol 3′-kinase: Stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit
-
Yu J., Zhang Y., McIlroy J., Rordorf-Nikolic T., Orr G.A., Backer J.M. Regulation of the p85/p110 phosphatidylinositol 3′-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit. Mol. Cell. Biol. 18:1998;1379-1387.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1379-1387
-
-
Yu, J.1
Zhang, Y.2
McIlroy, J.3
Rordorf-Nikolic, T.4
Orr, G.A.5
Backer, J.M.6
-
75
-
-
0032514801
-
Regulation of the p85/p110alpha phosphatidylinositol 3′-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains
-
Yu J., Wjasow C., Backer J.M. Regulation of the p85/p110alpha phosphatidylinositol 3′-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains. J. Biol. Chem. 273:1998;30199-30203.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 30199-30203
-
-
Yu, J.1
Wjasow, C.2
Backer, J.M.3
-
76
-
-
0032510136
-
Involvement of p85 in p53-dependent apoptotic response to oxidative stress
-
Yin Y., Terauchi Y., Solomon G.G., Aizawa S., Rangarajan P.N., Yazaki Y., Kadowaki T., Barrett J.C. Involvement of p85 in p53-dependent apoptotic response to oxidative stress. Nature. 391:1998;707-710.
-
(1998)
Nature
, vol.391
, pp. 707-710
-
-
Yin, Y.1
Terauchi, Y.2
Solomon, G.G.3
Aizawa, S.4
Rangarajan, P.N.5
Yazaki, Y.6
Kadowaki, T.7
Barrett, J.C.8
-
77
-
-
0033602361
-
Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity
-
Zhu J., Jiang J., Zhou W., Zhu K., Chen X. Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity. Oncogene. 18:1999;2149-2155.
-
(1999)
Oncogene
, vol.18
, pp. 2149-2155
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Zhu, K.4
Chen, X.5
-
78
-
-
0032532553
-
Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers
-
Simms L.A., Radford-Smith G., Biden K.G., Buttenshaw R., Cummings M., Jass J.R., Young J., Meltzer S.J., Leggett B.A. Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers. Oncogene. 17:1998;2003-2008.
-
(1998)
Oncogene
, vol.17
, pp. 2003-2008
-
-
Simms, L.A.1
Radford-Smith, G.2
Biden, K.G.3
Buttenshaw, R.4
Cummings, M.5
Jass, J.R.6
Young, J.7
Meltzer, S.J.8
Leggett, B.A.9
-
79
-
-
0032590011
-
PIK3CA is implicated as an oncogene in ovarian cancer [see comments]
-
Shayesteh L., Lu Y., Kuo W.L., Baldocchi R., Godfrey T., Collins C., Pinkel D., Powell B., Mills G.B., Gray J.W. PIK3CA is implicated as an oncogene in ovarian cancer [see comments]. Nat. Genet. 21:1999;99-102.
-
(1999)
Nat. Genet.
, vol.21
, pp. 99-102
-
-
Shayesteh, L.1
Lu, Y.2
Kuo, W.L.3
Baldocchi, R.4
Godfrey, T.5
Collins, C.6
Pinkel, D.7
Powell, B.8
Mills, G.B.9
Gray, J.W.10
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