Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription

Nucleic Acids Research

Volumn 29, Issue 3, 2001, Pages 767-773

  Chao, Sheng Hao ^a   Greenleaf, Arno L ^b   Price, David H ^a  

^a UNIVERSITY OF IOWA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS TRANS ISOMERASE; DNA; DNA DIRECTED RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE III; ISOMERASE INHIBITOR; JUGLONE; N ETHYLMALEIMIDE; PROLINE; RECOMBINANT PROTEIN; RNA; RNA POLYMERASE II; SINGLE STRANDED DNA; THIOL GROUP;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA TRANSCRIPTION; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN TARGETING; REPORTER GENE; RNA TRANSLATION; TRANSCRIPTION INITIATION;

EID: 0035253619     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.3.767     Document Type: Article

References (37)

1. Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts
2. Phosphorylation-dependent prolyl isomerization: A novel cell cycle regulatory mechanism
3. Mutations in a peptidylprolyl-cis/trans-isomerase gene lead to a defect in 3′-end formation of a pre-mRNA in Saccharomyces cerevisiae
4. Confirmation of the existence of a third family among peptidyl-prolyl cis/trans isomerases. Amino acid sequence and recombinant production of parvulin
5. The dodo gene family encodes a novel protein involved in signal transduction and protein folding
6. The Arabidopsis thaliana PIN1 At gene encodes a single-domain phosphorylation-dependent peptidyl prolyl cis/trans isomerase
7. A human peptidyl-prolyl isomerase essential for regulation of mitosis
8. Function of WW domains as phosphoserine- or phosphothreonine-binding modules
9. Phosphorylation of mammalian RNA polymerase II
10. Coupling RNA polymerase II transcription with pre-mRNA processing
11. Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3′-end formation
12. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone
13. Control of RNA polymerase II elongation potential by a novel carboxyl-terminal domain kinase
14. Interplay between positive and negative elongation factors: Drawing a new view of DRB
15. P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II
16. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins
17. Control of formation of two distinct classes of RNA polymerase II elongation complexes
18. Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimer
19. RNA polymerase III transcription repressed by Rb through its interactions with TFIIIB and TFIIIC2
20. c cell nuclear extracts
21. Animal DNA-dependent RNA polymerases. 10. General enzymatic properties of purified calf thymus RNA polymerases A1 and B
22. RNA elongation by RNA polymerase II is not inhibited by N-ethylmaleimide or iodoacetamide
23. Animal DNA-dependent RNA polymerases. 11. Mechanism of the inhibition of RNA polymerases B by amatoxins
24. Novobiocin inhibits initiation of RNA polymerase II-directed transcription of the mouse metallothionein-I gene independent of its effect on DNA topoisomerase II
25. Novobiocin inhibits interactions required for yeast TFIIIB sequestration during stable transcription complex formation in vitro
26. Inhibition of RNA polymerase I-directed transcription by novobiocin. Potential use of novobiocin as a general inhibitor of eukaryotic transcription initiation
27. Novobiocin interferes with the binding of transcription factors TFIIIA and TFIIIC to the promoters of class III genes
28. Tagetitoxin: A new inhibitor of eukaryotic transcription by RNA polymerase III
29. Tagetitoxin inhibits RNA synthesis directed by RNA polymerases from chloroplasts and Escherichia coli
30. Mechanistic aspects of tagetitoxin inhibition of RNA polymerase from Escherichia coli
31. Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II
32. Stability of Drosophila RNA polymerase II elongation complexes in vitro
33. Regulation of gene expression by TBP-associated proteins
34. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest
35. Flavopiridol inhibits P-TEFb and blocks HIV-1 replication