Synergy between tumor suppressor APC and the β-catenin-Tcf4 target Tcf1

Science

Volumn 285, Issue 5435, 1999, Pages 1923-1926

  Roose, Jeroen ^a   Huls, Gerwin ^a   Van Beest, Moniek ^a   Moerer, Petra ^a   Van Der Horn, Karin ^a   Goldschmeding, Roel ^a   Logtenberg, Ton ^a   Clevers, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; TRANSCRIPTION FACTOR;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST ADENOMA; CELL TRANSFORMATION; FEEDBACK SYSTEM; GENE ACTIVATION; GENE MUTATION; HISTOPATHOLOGY; INTESTINE EPITHELIUM; INTESTINE POLYP; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TUMOR SUPPRESSOR GENE;

ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; INTESTINAL NEOPLASMS; LYMPHOID ENHANCER-BINDING FACTOR 1; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEOPLASM PROTEINS; PROMOTER REGIONS (GENETICS); T CELL TRANSCRIPTION FACTOR 1; TCF TRANSCRIPTION FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0033578918     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5435.1923     Document Type: Article

References (55)

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55. We thank the Department of Pathology and the Audio-Visual Center for support, K. Kinzler for the HT-29 cell lines, and R. Fodde and colleagues for helpful discussions.