Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition

Immunity

Volumn 18, Issue 3, 2003, Pages 355-365

  Goping, Ing Swie ^a   Barry, Michele ^a   Liston, Peter ^b   Sawchuk, Tracy ^a   Constantinescu, Gabriela ^a   Michalak, Karolina M ^a   Shostak, Irene ^a   Roberts, Darren L ^a   Hunter, Allison M ^b   Korneluk, Robert ^b   Bleackley, R Chris ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; CELL PROTEIN; GRANZYME B; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BCL 2; PROTEIN P17; PROTEIN P20; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING;

EID: 0037343068     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(03)00032-3     Document Type: Article

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