Cleavage of CPP32 by granzyme B represents a critical role for granzyme B in the induction of target cell DNA fragmentation

Journal of Biological Chemistry

Volumn 271, Issue 36, 1996, Pages 21709-21712

  Darmon, Alison J ^a   Ley, Timothy J ^b   Nicholson, Donald W ^c   Bleackley, R Chris ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; DNA FRAGMENT; FAS ANTIGEN; GRANZYME B; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA DEGRADATION; ENZYME DEFICIENCY; ENZYME DEGRADATION; ETIOLOGY; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; APOPTOSIS; CAENORHABDITIS ELEGANS PROTEINS; CASPASE 1; CASPASE 3; CASPASES; CELL LINE; CHROMIUM; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DIMETHYL SULFOXIDE; DNA; DNA DAMAGE; GRANZYMES; HELMINTH PROTEINS; MICE; OLIGOPEPTIDES; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC; THYMIDINE;

EID: 0029832173     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.36.21709     Document Type: Article

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