-
1
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
4
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
(1994)
Nature
, vol.369
, pp. 31-37
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Seiler, P.4
Odermatt, B.5
Olsen, K.J.6
Podack, E.R.7
Zinkernagel, R.M.8
Hengartner, H.9
-
5
-
-
10544252275
-
New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29073-29079
-
-
Froelich, C.J.1
Orth, K.2
Turbov, J.3
Seth, P.4
Gottlieb, R.5
Babior, B.6
Shah, G.M.7
Bleackley, R.C.8
Dixit, V.M.9
Hanna, W.10
-
6
-
-
0033499729
-
Cytosolic delivery of granzyme B by bacterial toxins: Evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8604-8615
-
-
Browne, K.A.1
Blink, E.2
Sutton, V.R.3
Froelich, C.J.4
Jans, D.A.5
Trapani, J.A.6
-
9
-
-
0030008812
-
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16720-16724
-
-
Duan, H.1
Orth, K.2
Chinnaiyan, A.M.3
Poirier, G.G.4
Froelich, C.J.5
He, W.W.6
Dixit, V.M.7
-
11
-
-
0032147225
-
Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis
-
(1998)
Blood
, vol.92
, pp. 1044-1054
-
-
Pinkoski, M.J.1
Hobman, M.2
Heibein, J.A.3
Tomaselli, K.4
Li, F.5
Seth, P.6
Froelich, C.J.7
Bleackley, R.C.8
-
13
-
-
0035853855
-
Granzyme B-mediated apoptosis proceeds predominantly through a BCL-2-inhibitable mitrochondrial pathway
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12060-12067
-
-
Pinkoski, M.J.1
Waterhouse, N.J.2
Jeffrey, A.3
Heibein, B.4
Wolf, B.5
Kuwana, T.6
Goldstein, J.C.7
Newmeyer, D.D.8
Bleackley, R.C.9
Green, D.R.10
-
15
-
-
0034694091
-
Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1403-1414
-
-
Sutton, V.R.1
Davis, J.E.2
Cancilla, M.3
Johnstone, R.W.4
Ruefli, A.A.5
Sedelies, K.6
Browne, K.A.7
Trapani, J.A.8
-
20
-
-
0035793580
-
Lysosomal protease pathways to apoptosis: Cleavage of bid, not pro-caspases, is the most likely route
-
(2000)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredesen, D.8
Freeze, H.9
Abrahamson, M.10
-
21
-
-
0034640102
-
Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
-
(2000)
Cell
, vol.101
, pp. 389-399
-
-
Li, K.1
Li, Y.2
Shelton, J.M.3
Richardson, J.A.4
Spencer, E.5
Chen, Z.J.6
Wang, X.7
Williams, R.S.8
-
25
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
(2000)
Genes Dev.
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
27
-
-
0033535350
-
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
-
(1999)
J. Cell Biol.
, vol.144
, pp. 891-901
-
-
Desagher, S.1
Osen-Sand, A.2
Nichols, A.3
Eskes, R.4
Montessuit, S.5
Lauper, S.6
Maundrell, K.7
Antonsson, B.8
Martinou, J.C.9
-
29
-
-
0035823558
-
A role for mitochondial Bak in apoptotic response to anticancer drugs
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34307-34317
-
-
Wang, G.Q.1
Gastman, B.R.2
Wieckowski, E.3
Goldstein, L.A.4
Gambotto, A.5
Kim, T.H.6
Fang, B.7
Rabinovitz, A.8
-
31
-
-
0034652461
-
Adenoviral Bak overexpression mediates caspase-dependent tumor killing
-
(2000)
Cancer Res.
, vol.60
, pp. 788-792
-
-
Pataer, A.1
Fang, B.2
Yu, R.3
Kagawa, S.4
Hunt, K.K.5
McDonnell, T.J.6
Roth, J.A.7
Swisher, S.G.8
-
34
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
(1998)
J. Cell Biol.
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
36
-
-
0034721646
-
Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis
-
(2000)
Cell
, vol.103
, pp. 491-500
-
-
Motyka, B.1
Korbutt, G.2
Pinkoski, M.J.3
Heibein, J.A.4
Caputo, A.5
Hobman, M.6
Barry, M.7
Shostak, I.8
Sawchuk, T.9
Holmes, C.F.10
-
41
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
(1999)
Nature
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
Zhao, Y.4
Zinkel, S.5
Klocke, B.6
Roth, K.A.7
Korsmeyer, S.J.8
-
46
-
-
0033598718
-
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13950-13955
-
-
Mullbacher, A.1
Waring, P.2
Tha Hla, R.3
Tran, T.4
Chin, S.5
Stehle, T.6
Museteanu, C.7
Simon, M.M.8
-
48
-
-
0031459164
-
Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 3492-3498
-
-
Medema, J.P.1
Toes, R.E.2
Scaffidi, C.3
Zheng, T.S.4
Flavell, R.A.5
Melief, C.J.6
Peter, M.E.7
Offringa, R.8
Krammer, P.H.9
-
53
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
55
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
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