Assessment of blood-brain barrier penetration: In silico, in vitro and in vivo

Current Drug Metabolism

Volumn 3, Issue 6, 2002, Pages 647-657

  Feng, Meihua R ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CEFALOTIN; CIMETIDINE; CYCLOSPORIN A; DIGOXIN; GABAPENTIN; GLYCOPROTEIN P; INDOMETACIN; INSULIN; IVERMECTIN; KANAMYCIN; LOPERAMIDE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; OFLOXACIN; PENICILLIN G; PIPERAZINE DERIVATIVE; PREGABALIN; PROTEIN INHIBITOR; QUINOLINE DERIVED ANTIINFECTIVE AGENT; STREPTOMYCIN; TOBRAMYCIN; UNINDEXED DRUG; VALSPODAR; VINBLASTINE; XENOBIOTIC AGENT; ZIDOVUDINE;

ANALYTIC METHOD; ARTERY PERFUSION; AUTORADIOGRAPHY; BLOOD BRAIN BARRIER; CAROTID ARTERY; CELL CULTURE; CENTRAL NERVOUS SYSTEM; CHEMICAL STRUCTURE; COMPUTER MODEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE PERMEABILITY; MICRODIALYSIS; MOUSE; NONHUMAN; PHARMACODYNAMICS; PREDICTION; RAT; REVIEW;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; COMPUTER SIMULATION; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS;

EID: 0036889901     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389200023337063     Document Type: Review

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