Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 1, 1997, Pages 293-304

  Ooie, Tsuyoshi ^a,b   Terasaki, Tetsuya ^a,c   Suzuki, Hiroshi ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYORIN PHARMACEUTICAL CO LTD   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FLEROXACIN; GATIFLOXACIN; NORFLOXACIN; OFLOXACIN; PEFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

AGITATION; ANIMAL CELL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ANXIETY NEUROSIS; ARTICLE; BLOOD BRAIN BARRIER; CONFUSION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG UPTAKE; HALLUCINATION; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; MALE; MATHEMATICAL ANALYSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

4-QUINOLONES; ANIMALS; ANTI-INFECTIVE AGENTS; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD-BRAIN BARRIER; BRAIN; KINETICS; RATS;

EID: 0030799004     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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