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Journal of Pharmaceutical Sciences

Volumn 85, Issue 12, 1996, Pages 1336-1340

How structural features influence the biomembrane permeability of peptides

(5) Burton, Philip S a Conradi, Robert A a Ho, Norman F H a Hilgers, Allen R a Borchardt, Ronald T b

a PFIZER INC (United States)

b UNIVERSITY OF KANSAS (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAM ANTIBIOTIC; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; OLIGOMER; PHENYLALANINE DERIVATIVE; SYNTHETIC PEPTIDE; VERAPAMIL;

ARTICLE; BLOOD BRAIN BARRIER; CELL MEMBRANE TRANSPORT; CELL STRAIN CACO 2; DRUG BIOAVAILABILITY; DRUG DIFFUSION; DRUG TRANSPORT; HUMAN; HUMAN CELL; HYDROGEN BOND; INTESTINE EPITHELIUM CELL; LIPOPHILICITY; OLIGOMERIZATION; PHYSICAL CHEMISTRY;

EID: 0030458462 PISSN: 00223549 EISSN: None Source Type: Journal
DOI: 10.1021/js960067d Document Type: Article

Times cited : (164)

References (55)

1
- 0025954040
- Nellins, H. Adv. Drug Deliv. Rev. 1991, 7, 339-364.
- (1991) Adv. Drug Deliv. Rev. , vol.7 , pp. 339-364
- Nellins, H.¹

2
- 0000727573
- Johnson, L. R., Ed.; Raven: New York
- Madara, J. L. and Trier, J. S. In Physiology of the Gastrointestinal Tract; Johnson, L. R., Ed.; Raven: New York, 1987; pp 1209-1249.
- (1987) Physiology of the Gastrointestinal Tract , pp. 1209-1249
- Madara, J.L.¹ Trier, J.S.²

3
- 12644249779
- Academic: Orlando, FL
- Klausner, R. D.; Kempf, C.; Renswoude, J. In Membrane Structure and Function: Current Topics in Membranes and Transport, Vol. 29; Academic: Orlando, FL; 1987.
- (1987) Membrane Structure and Function: Current Topics in Membranes and Transport, Vol. 29 , vol.29
- Klausner, R.D.¹ Kempf, C.² Renswoude, J.³

4
- 0003923044
- Academic: San Diego, CA
- Stein, E. D. Channels, Carriers and Pumps, An Introduction to Membrane Transport; Academic: San Diego, CA; 1990.
- (1990) Channels, Carriers and Pumps, An Introduction to Membrane Transport
- Stein, E.D.¹

5
- 0017264094
- Schultz, S. G. Kidney Int. 1976, 9, 65-75.
- (1976) Kidney Int. , vol.9 , pp. 65-75
- Schultz, S.G.¹

6
- 12644311895
- Johnson, L. R., Ed.; Raven: New York
- Jackson, M. J. In Physiology of the Gastrointestinal Tract; Johnson, L. R., Ed.; Raven: New York, 1987; pp 1587-1621.
- (1987) Physiology of the Gastrointestinal Tract , pp. 1587-1621
- Jackson, M.J.¹

7
- 0016722069
- Smith, R. N.; Hansch, C.; Ames, M. M. J. Pharm. Sci. 1975, 64, 599-606.
- (1975) J. Pharm. Sci. , vol.64 , pp. 599-606
- Smith, R.N.¹ Hansch, C.² Ames, M.M.³

8
- 0002544211
- Topless, J. G., Ed.; Academic: New York
- Austel, V.; Kutter, E. In Quantative Structure-Activity Relationships of Drugs: Topless, J. G., Ed.; Academic: New York, 1980; pp 437-496.
- (1980) Quantative Structure-Activity Relationships of Drugs , pp. 437-496
- Austel, V.¹ Kutter, E.²

9
- 8644243613
- Leo, A.; Hansch, C.; Elkins, D. Chem. Rev. 1977, 71, 525-616.
- (1977) Chem. Rev. , vol.71 , pp. 525-616
- Leo, A.¹ Hansch, C.² Elkins, D.³

10
- 0001255549
- Yalkowsky, S. H.; Morozowich, W. Drug Design 1980, 9, 122-185.
- (1980) Drug Design , vol.9 , pp. 122-185
- Yalkowsky, S.H.¹ Morozowich, W.²

11
- 0019124032
- Levin, V. A. J. Med. Chem. 1980, 23, 682-684.
- (1980) J. Med. Chem. , vol.23 , pp. 682-684
- Levin, V.A.¹

12
- 0026756068
- Bernards, M. D.; Hill, H. F. Anesthesiology 1992, 77, 750-756.
- (1992) Anesthesiology , vol.77 , pp. 750-756
- Bernards, M.D.¹ Hill, H.F.²

13
- 0024578889
- Macheras, P. E.; Symillides, M. Y. Biopharm. Drug Dispos. 1989, 10, 43-53.
- (1989) Biopharm. Drug Dispos. , vol.10 , pp. 43-53
- Macheras, P.E.¹ Symillides, M.Y.²

14
- 0023923405
- Nook, T.; Doelker, E.; Buri, P. Int. J. Pharm. 1988, 43, 119-129.
- (1988) Int. J. Pharm. , vol.43 , pp. 119-129
- Nook, T.¹ Doelker, E.² Buri, P.³

15
- 0018850819
- Komiya, I.; Park, J. Y.; Kamani, A.; Ho, N. F. H.; Higuchi, W. I. Int. J. Pharm. 1980, 4, 249-262.
- (1980) Int. J. Pharm. , vol.4 , pp. 249-262
- Komiya, I.¹ Park, J.Y.² Kamani, A.³ Ho, N.F.H.⁴ Higuchi, W.I.⁵

16
- 0001935155
- Roche, E. B., Ed.; American Pharmaceutical Association, Academy of Pharm. Sci.: Washington, D. C.
- Ho, N. F. H.; Park, J. Y.; Morozowich, W.; Higuchi, W. I. In Design of Biopharmaceutical Properties Through Prodrugs and Analogs; Roche, E. B., Ed.; American Pharmaceutical Association, Academy of Pharm. Sci.: Washington, D. C., 1977; pp 136-227.
- (1977) Design of Biopharmaceutical Properties Through Prodrugs and Analogs , pp. 136-227
- Ho, N.F.H.¹ Park, J.Y.² Morozowich, W.³ Higuchi, W.I.⁴

17
- 0024267858
- Van Bree, J. B. M. M.; De Boer, A. G.; Danhof, M.; Ginsel, L. A.; Breimer, D. D. J. Pharmacol. Exp. Ther. 1988, 247, 1233-1239.
- (1988) J. Pharmacol. Exp. Ther. , vol.247 , pp. 1233-1239
- Van Bree, J.B.M.M.¹ De Boer, A.G.² Danhof, M.³ Ginsel, L.A.⁴ Breimer, D.D.⁵

18
- 0024437870
- Tavakoli-Saberi, M. R.; Audus, K. L. Int. J. Pharm. 1989, 56, 135-142.
- (1989) Int. J. Pharm. , vol.56 , pp. 135-142
- Tavakoli-Saberi, M.R.¹ Audus, K.L.²

19
- 0016289401
- Westergaard, H.; Dietschy, J. M. J. Clin. Invest. 1974, 54, 718-732
- (1974) J. Clin. Invest. , vol.54 , pp. 718-732
- Westergaard, H.¹ Dietschy, J.M.²

20
- 0022349214
- Banks, W. A.; Kastin, A. J. Brain Res. Bull. 1985, 15, 287-292.
- (1985) Brain Res. Bull. , vol.15 , pp. 287-292
- Banks, W.A.¹ Kastin, A.J.²

21
- 0025357318
- Odoom, J. E.; Campbell, I. D.; Ellory, J. C.; King, G. F. Biochem. J. 1990, 267, 141-147.
- (1990) Biochem. J. , vol.267 , pp. 141-147
- Odoom, J.E.¹ Campbell, I.D.² Ellory, J.C.³ King, G.F.⁴

22
- 0025087968
- Begley, D. J.; Squires, L. K.; Zlokovic, B. V.; Mitrovic, D. M.; Hughes, C. C. W.; Revest, P. A.; Greenwood, J. J. Neurochem. 1990, 55, 1222-1230.
- (1990) J. Neurochem. , vol.55 , pp. 1222-1230
- Begley, D.J.¹ Squires, L.K.² Zlokovic, B.V.³ Mitrovic, D.M.⁴ Hughes, C.C.W.⁵ Revest, P.A.⁶ Greenwood, J.⁷

23
- 0025774429
- Muranishi, S.; Sakai, A.; Yamada, K.; Murakami, M.; Takada, K; Kiso, Y. Pharm. Res. 1991, 8, 649-652.
- (1991) Pharm. Res. , vol.8 , pp. 649-652
- Muranishi, S.¹ Sakai, A.² Yamada, K.³ Murakami, M.⁴ Takada, K.⁵ Kiso, Y.⁶

24
- 0027472110
- Kahns, A. H.; Buur, A.; Bundhaard, H. Pharm. Res. 1993, 10, 68-74.
- (1993) Pharm. Res. , vol.10 , pp. 68-74
- Kahns, A.H.¹ Buur, A.² Bundhaard, H.³

25
- 0027953633
- Kararli, T. T.; Farhadieh, B.; Bittner, S.; Babler, M.; Yarg, P-C.; Walsh, G. M. Int. J. Pharm. 1994, 102, 177-184.
- (1994) Int. J. Pharm. , vol.102 , pp. 177-184
- Kararli, T.T.¹ Farhadieh, B.² Bittner, S.³ Babler, M.⁴ Yarg, P.-C.⁵ Walsh, G.M.⁶

26
- 0028904424
- Hamilton, H. W.; Steinbaugh, B. A.; Stewart, B. H.; Chan, O. H.; Schmid, H. L.; Schroeder, R.; Ryan, M. J.; Keiser, J.; Taylor, M. D.; Blankley, C. J.; Kaltenbronn, J. S.; Wright, J.; Hicks, J. J. Med. Chem. 1995, 38, 1446-1455.
- (1995) J. Med. Chem. , vol.38 , pp. 1446-1455
- Hamilton, H.W.¹ Steinbaugh, B.A.² Stewart, B.H.³ Chan, O.H.⁴ Schmid, H.L.⁵ Schroeder, R.⁶ Ryan, M.J.⁷ Keiser, J.⁸ Taylor, M.D.⁹ Blankley, C.J.¹⁰ Kaltenbronn, J.S.¹¹ Wright, J.¹² Hicks, J.¹³

27
- 0028923458
- Walter, E.; Kissel, T.; Reers, M.; Dickneite, G.; Hoffman, D.; Stüber, W. Pharm. Res. 1995, 12, 360-365.
- (1995) Pharm. Res. , vol.12 , pp. 360-365
- Walter, E.¹ Kissel, T.² Reers, M.³ Dickneite, G.⁴ Hoffman, D.⁵ Stüber, W.⁶

28
- 0025999171
- Conradi, R. A.; Hilgers, A. R.; Ho, N. F. H.; Burton, P. S. Pharm. Res., 1991, 8, 1453-1459.
- (1991) Pharm. Res. , vol.8 , pp. 1453-1459
- Conradi, R.A.¹ Hilgers, A.R.² Ho, N.F.H.³ Burton, P.S.⁴

29
- 0026513211
- Conradi, R. A.; Hilgers, A. R.; Ho, N. F. H.; Burton, P. S. Pharm. Res. 1992, 9, 435-439.
- (1992) Pharm. Res. , vol.9 , pp. 435-439
- Conradi, R.A.¹ Hilgers, A.R.² Ho, N.F.H.³ Burton, P.S.⁴

30
- 0021067619
- Pinto, M.; Ronine-Leon, S., Appay, M. D.; Kidinger, M.; Triadov, N.; Dussaulx, E.; Lacroix, B.; Simon-Assmann, P.; Hoffen, K.; Fogh, J.; Zwiebaum, A. Biol. Cell 1983, 47, 323-330.
- (1983) Biol. Cell , vol.47 , pp. 323-330
- Pinto, M.¹ Ronine-Leon, S.² Appay, M.D.³ Kidinger, M.⁴ Triadov, N.⁵ Dussaulx, E.⁶ Lacroix, B.⁷ Simon-Assmann, P.⁸ Hoffen, K.⁹ Fogh, J.¹⁰ Zwiebaum, A.¹¹

31
- 0024593744
- Hidalgo, I. J.; Raub, T. J.; Borchardt, R. T. Gastroenterology 1989, 96, 736-749.
- (1989) Gastroenterology , vol.96 , pp. 736-749
- Hidalgo, I.J.¹ Raub, T.J.² Borchardt, R.T.³

32
- 0025132942
- Hilgers, A. R.; Conradi, R. A.; Burton, P. S. Pharm. Res. 1990, 7, 902-910.
- (1990) Pharm. Res. , vol.7 , pp. 902-910
- Hilgers, A.R.¹ Conradi, R.A.² Burton, P.S.³

33
- 0025311288
- Artursson, P. J. Pharm. Sci. 1990, 79, 476-482.
- (1990) J. Pharm. Sci. , vol.79 , pp. 476-482
- Artursson, P.¹

34
- 0025189818
- Wilson, G.; Hassan, J. F.; Dix, C. J.; Williamson, I.; Shah, R.; Mackay, M.; Artursson, P. J. Contolled Release 1990, 11, 25-40.
- (1990) J. Contolled Release , vol.11 , pp. 25-40
- Wilson, G.¹ Hassan, J.F.² Dix, C.J.³ Williamson, I.⁴ Shah, R.⁵ Mackay, M.⁶ Artursson, P.⁷

35
- 0027497560
- Rubas, W.; Jezyk, N.; Grass, G. M. Pharm. Res. 1993, 10, 113-118.
- (1993) Pharm. Res. , vol.10 , pp. 113-118
- Rubas, W.¹ Jezyk, N.² Grass, G.M.³

36
- 0028080058
- Adson, A.; Raub, T. J.; Burton, P. S.; Barsuhn, C. L.; Hilgers, A. R.; Audus, K. L.; Ho, N. F. H. J. Pharm. Sci. 1994, 83, 1529-1536.
- (1994) J. Pharm. Sci. , vol.83 , pp. 1529-1536
- Adson, A.¹ Raub, T.J.² Burton, P.S.³ Barsuhn, C.L.⁴ Hilgers, A.R.⁵ Audus, K.L.⁶ Ho, N.F.H.⁷

37
- 0003411759
- Academic: New York
- Stein, W. D. The Movement of Molecules Across Cell Membranes; Academic: New York, 1967; pp 65-125.
- (1967) The Movement of Molecules Across Cell Membranes , pp. 65-125
- Stein, W.D.¹

38
- 0026535563
- Burton, P. S.; Conradi, R. A.; Hilgers, A. R.; Ho, N. F. H.; Maggiora, L. L. J. Controlled Release 1992, 19, 87-98.
- (1992) J. Controlled Release , vol.19 , pp. 87-98
- Burton, P.S.¹ Conradi, R.A.² Hilgers, A.R.³ Ho, N.F.H.⁴ Maggiora, L.L.⁵

39
- 0028261806
- Paterson, D. A.; Conradi, R. A.; Hilgers, A. R.; Vidmar, T. J.; Burton, P. S. Quant. Struct.-Act. Relat. 1994, 13, 4-10.
- (1994) Quant. Struct.-Act. Relat. , vol.13 , pp. 4-10
- Paterson, D.A.¹ Conradi, R.A.² Hilgers, A.R.³ Vidmar, T.J.⁴ Burton, P.S.⁵

40
- 0027141263
- Kim, D.-C.; Burton, P. S.; Borchardt, R. T. Pharm. Res. 1993, 10, 1710-1714.
- (1993) Pharm. Res. , vol.10 , pp. 1710-1714
- Kim, D.-C.¹ Burton, P.S.² Borchardt, R.T.³

41
- 0028270064
- Chikhale, E. G.; Ng, K.-Y.; Burton, P. S.; Borchardt, R. T. Pharm. Res. 1994, 11, 412-419.
- (1994) Pharm. Res. , vol.11 , pp. 412-419
- Chikhale, E.G.¹ Ng, K.-Y.² Burton, P.S.³ Borchardt, R.T.⁴

42
- 0027267598
- Burton, P. S.; Conradi, R. A.; Hilgers, A. R.; Ho, N. F. H. Biochem. Biophys. Res. Comm. 1993, 190, 760-766.
- (1993) Biochem. Biophys. Res. Comm. , vol.190 , pp. 760-766
- Burton, P.S.¹ Conradi, R.A.² Hilgers, A.R.³ Ho, N.F.H.⁴

43
- 0025040859
- Kane, S. E.; Pastan, I.; Gottesman, M. M. J. Bioenerg. Biomembr. 1990, 22, 593-618.
- (1990) J. Bioenerg. Biomembr. , vol.22 , pp. 593-618
- Kane, S.E.¹ Pastan, I.² Gottesman, M.M.³

44
- 0027120232
- Ling, V. Cancer 1992, 69, 2603-2609.
- (1992) Cancer , vol.69 , pp. 2603-2609
- Ling, V.¹

45
- 0029558244
- Ho, N. F. H.; Burton, P. S.; Conradi, R. A.; Barsuhn, C. L. J. Pharm. Sci. 1995, 84, 21-27.
- (1995) J. Pharm. Sci. , vol.84 , pp. 21-27
- Ho, N.F.H.¹ Burton, P.S.² Conradi, R.A.³ Barsuhn, C.L.⁴

46
- 0027730961
- Augustijns, P. F.; Bradshaw, T. P.; Gan, L. S.; Hendren, R. W.; Thakker, D. R. Biochem. Biophys. Res. Comm. 1993, 197, 360-365.
- (1993) Biochem. Biophys. Res. Comm. , vol.197 , pp. 360-365
- Augustijns, P.F.¹ Bradshaw, T.P.² Gan, L.S.³ Hendren, R.W.⁴ Thakker, D.R.⁵

47
- 85030290725
- unpublished results
- Bafna, S.; Conradi, R. A.; Hilgers, A. R.; Ho, N. F. H.; Burton, P. S., unpublished results.
- Bafna, S.¹ Conradi, R.A.² Hilgers, A.R.³ Ho, N.F.H.⁴ Burton, P.S.⁵

48
- 0029085951
- Burton, P. S.; Bafna, S.; Conradi, R. A.; Ho, N. F. H.; Hilgers, A. R. Proceed. Intern. Symp. Controlled Release Bioact. Mater. 1995, 22, 602-603.
- (1995) Proceed. Intern. Symp. Controlled Release Bioact. Mater. , vol.22 , pp. 602-603
- Burton, P.S.¹ Bafna, S.² Conradi, R.A.³ Ho, N.F.H.⁴ Hilgers, A.R.⁵

49
- 0004165677
- Pitman Advanced Publishing Program: Boston
- Höfer, M. Transport Across Biological Membranes; Pitman Advanced Publishing Program: Boston, 1981; pp 36-55.
- (1981) Transport Across Biological Membranes , pp. 36-55
- Höfer, M.¹

50
- 85030286671
- unpublished results
- Ho, N. F. H.; Day, J. S.; Burton, P. S., unpublished results.
- Ho, N.F.H.¹ Day, J.S.² Burton, P.S.³

51
- 0028932174
- Chikhale, E. G.; Burton, P. S.; Borchardt, R. T. J. Pharmacol. Exp. Ther. 1995, 273, 298-303.
- (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 298-303
- Chikhale, E.G.¹ Burton, P.S.² Borchardt, R.T.³

52
- 0026255075
- Burton, P. S.; Conradi, R. A.; Hilgers, A. R. Adv. Drug Deliv. Rev. 1991, 7, 365-386.
- (1991) Adv. Drug Deliv. Rev. , vol.7 , pp. 365-386
- Burton, P.S.¹ Conradi, R.A.² Hilgers, A.R.³

53
- 0003670171
- Pliska, V.; Testa, B.; van de Waterbeemd, H., Eds.; VCH Weinheim, B. R. D., in press
- Conradi, R. A.; Burton, P. S.; Borchardt, R. T. In Lipophilicity in Drug Action and Toxicity; Pliska, V.; Testa, B.; van de Waterbeemd, H., Eds.; VCH Weinheim, B. R. D., in press.
- Lipophilicity in Drug Action and Toxicity
- Conradi, R.A.¹ Burton, P.S.² Borchardt, R.T.³

54
- 0028229150
- Schinkel, A. H.; Smit, J. J. M.; van Tellingen, O.; Beijnen, J. H.; Wagennar. E.; van Deemster, L.; Mol, C. A. A. M.; van der Valk, M. A.; Robanus-Maandag, E. C., Reile, H. P. J.; Berns, A. J. M.; Borst, P. Cell 1994, 77, 491-502.
- (1994) Cell , vol.77 , pp. 491-502
- Schinkel, A.H.¹ Smit, J.J.M.² Van Tellingen, O.³ Beijnen, J.H.⁴ Wagennar, E.⁵ Van Deemster, L.⁶ Mol, C.A.A.M.⁷ Van Der Valk, M.A.⁸ Robanus-Maandag, E.C.⁹ Reile, H.P.J.¹⁰ Berns, A.J.M.¹¹ Borst, P.¹²

55
- 0029013159
- Leveque, D.; Jehl, F. Anticancer Res. 1995, 15, 331-336.
- (1995) Anticancer Res. , vol.15 , pp. 331-336
- Leveque, D.¹ Jehl, F.²

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