Theoretical descriptors in quantitative structure-affinity and selectivity relationship study of potent N4-substituted arylpiperazine 5-HT1(A) receptor antagonists

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 5, 1998, Pages 535-550

  Menziani, M C ^a   De Benedetti, P G ^a   Karelson, M ^b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF TARTU   (Estonia)

Author keywords

1 adrenoceptor selectivity; 5 HT1(A) receptor antagonists; CODESSA; QSAR; Theoretical descriptors

Indexed keywords

RECEPTOR SUBTYPE; SEROTONIN 1A ANTAGONIST;

ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

MOLECULAR STRUCTURE; PIPERAZINES; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031799903     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00008-X     Document Type: Article

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