Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier

Journal of Pharmaceutical Sciences

Volumn 90, Issue 11, 2001, Pages 1681-1698

  Gumbleton, Mark ^a   Audus, Kenneth L ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

Blood brain barrier; Brain capillary endothelial cell; Cell culture; In vitro model; Permeability; Transendothelial transport

Indexed keywords

ANIMAL CELL; BLOOD BRAIN BARRIER; CELL CULTURE; CELL IMMORTALIZATION; CELL INTERACTION; CENTRAL NERVOUS SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; DRUG SCREENING; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; REVIEW;

EID: 0035156232     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.1119     Document Type: Review

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