Theoretical calculation and prediction of brain-blood partitioning of organic solutes using MolSurf parametrization and PLS statistics

Journal of Pharmaceutical Sciences

Volumn 87, Issue 8, 1998, Pages 952-959

  Norinder, Ulf ^a   Sjöberg, Per ^b   Österberg, Thomas ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b Qemist AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2 BUTANONE; 2 PROPANOL; ACETONE; BENZENE; BUTANE; CYCLOPENTANE; ENFLURANE; ETHER; FLUROXENE; HALOTHANE; HEPTANE; HEXANE; ISOBUTANOL; ISOFLURANE; METHANE; NITROGEN; PENTANE; PROPANOL; TOLUENE; TRICHLOROETHANE; TRICHLOROETHYLENE;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CELL MEMBRANE PERMEABILITY; CENTRAL NERVOUS SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; ENDOTHELIUM CELL; PARTITION COEFFICIENT; PRINCIPAL COMPONENT ANALYSIS; STATISTICAL ANALYSIS;

EID: 0031827249     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970439y     Document Type: Article

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