Prediction of the brain-blood distribution of a large set of drugs from structurally derived descriptors using partial least-squares (PLS) modeling

Journal of Chemical Information and Computer Sciences

Volumn 39, Issue 2, 1999, Pages 396-404

  Luco, Juan M ^a  

^a UNIVERSIDAD NACIONAL DE SAN LUIS   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOD BRAIN BARRIER; CHEMISTRY; HUMAN; PERMEABILITY; PHARMACOKINETICS; PHYSIOLOGY; REGRESSION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BLOOD-BRAIN BARRIER; HUMANS; LEAST-SQUARES ANALYSIS; MODELS, BIOLOGICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033088690     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci980411n     Document Type: Article

References (42)

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