메뉴 건너뛰기




Volumn 14, Issue 3, 1997, Pages 267-288

Application of microdialysis in pharmacokinetic studies

Author keywords

Blood brain barrier; Drug distribution; Extracellular fluid; Microdialysis sampling; Pharmacokinetics; Probe recovery

Indexed keywords

ANALGESIC AGENT; ANTICONVULSIVE AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; BACLOFEN; CAFFEINE; CEFTAZIDIME; CEFTRIAXONE; CYCLOSPORIN A; ETOPOSIDE; FLUOROURACIL; FLURBIPROFEN; GENTAMICIN; INSULIN; MANNITOL; METHOTREXATE; MORPHINE; NICOTINE; OPIATE; PARACETAMOL; PHENAZONE; PROBENECID; PROPRANOLOL; TACRINE; THEOBROMINE; THEOPHYLLINE; UNINDEXED DRUG; VALPROIC ACID; ZIDOVUDINE;

EID: 0030942858     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012081501464     Document Type: Review
Times cited : (284)

References (182)
  • 1
    • 0025338073 scopus 로고
    • Effects of different semipermeable membranes on in vitro and in vivo performance of microdialysis probes
    • J. K. Hsiao, B. A. Ball, P. F. Morrison, I. N. Mefford, and P. M. Bungay. Effects of different semipermeable membranes on in vitro and in vivo performance of microdialysis probes. J. Neurochem. 54:1449-1452 (1990).
    • (1990) J. Neurochem. , vol.54 , pp. 1449-1452
    • Hsiao, J.K.1    Ball, B.A.2    Morrison, P.F.3    Mefford, I.N.4    Bungay, P.M.5
  • 2
    • 0027232178 scopus 로고
    • Microdialysis in pharmacokinetics
    • L. Stahle. Microdialysis in pharmacokinetics. Eur. J. Drug Metab Pharmacok. 18:89-96 (1993).
    • (1993) Eur. J. Drug Metab Pharmacok. , vol.18 , pp. 89-96
    • Stahle, L.1
  • 3
    • 0026779589 scopus 로고
    • Pharmacokinetic estimations from microdialysis data
    • L. Stahle. Pharmacokinetic estimations from microdialysis data. Eur. J. Clin. Pharmacol. 43:289-294 (1992).
    • (1992) Eur. J. Clin. Pharmacol. , vol.43 , pp. 289-294
    • Stahle, L.1
  • 4
    • 0027495745 scopus 로고
    • Zero and first moment area estimation from microdialysis data
    • L. Stahle. Zero and first moment area estimation from microdialysis data. Eur. J. Clin. Pharmacol. 45:477-481 (1993).
    • (1993) Eur. J. Clin. Pharmacol. , vol.45 , pp. 477-481
    • Stahle, L.1
  • 5
    • 0028997392 scopus 로고
    • The use of microdialysis for the study of drug kinetics: Some methodological considerations illustrated with antipyrine in rat frontal cortex
    • P. N. Patsalos, W. T. Abed, M. S. Alavijeh, and M. T. O'Connell. The use of microdialysis for the study of drug kinetics: some methodological considerations illustrated with antipyrine in rat frontal cortex. Brit. J. Pharmacol. 115:503-509 (1995).
    • (1995) Brit. J. Pharmacol. , vol.115 , pp. 503-509
    • Patsalos, P.N.1    Abed, W.T.2    Alavijeh, M.S.3    O'Connell, M.T.4
  • 6
    • 0025106045 scopus 로고
    • Theophylline concentration in the extracellular space of the rat brain: Measurement by microdialysis and relation to behaviour
    • L. Stahle, S. Segersvard, and U. Ungerstedt. Theophylline concentration in the extracellular space of the rat brain: measurement by microdialysis and relation to behaviour. Eur. J. Pharmacol. 185:187-193 (1990).
    • (1990) Eur. J. Pharmacol. , vol.185 , pp. 187-193
    • Stahle, L.1    Segersvard, S.2    Ungerstedt, U.3
  • 7
    • 0026004926 scopus 로고
    • Quantitative microdialysis: Analysis of transients and application to pharmacokinetics in brain
    • P. F. Morrison, P. M. Bungay, J. K. Hsiao, B. A. Ball, I. N. Mefford, and R. L. Dedrick. Quantitative microdialysis: analysis of transients and application to pharmacokinetics in brain. J. Neurochem. 57:103-119 (1991).
    • (1991) J. Neurochem. , vol.57 , pp. 103-119
    • Morrison, P.F.1    Bungay, P.M.2    Hsiao, J.K.3    Ball, B.A.4    Mefford, I.N.5    Dedrick, R.L.6
  • 8
    • 0026501544 scopus 로고
    • Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis
    • S. L. Wong, Y. Wang, and R. J. Sawchuk. Analysis of zidovudine distribution to specific regions in rabbit brain using microdialysis. Pharm. Res. 9:332-338 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 332-338
    • Wong, S.L.1    Wang, Y.2    Sawchuk, R.J.3
  • 9
    • 0000815142 scopus 로고
    • The use of microdialysis for the in vivo study of skeletal muscle glucose metabolism
    • G. Marechal and U. Carraro (Eds.), Intersept Ltd., Andover, UK
    • J. Henriksson, H. Rosdahl, T. Fuchi, Y. Oshida, and U. Ungerstedt. The use of microdialysis for the in vivo study of skeletal muscle glucose metabolism. In: G. Marechal and U. Carraro (Eds.), Muscle and Molility, Vol. 2, Intersept Ltd., Andover, UK (1990).
    • (1990) Muscle and Molility , vol.2
    • Henriksson, J.1    Rosdahl, H.2    Fuchi, T.3    Oshida, Y.4    Ungerstedt, U.5
  • 10
    • 0026002719 scopus 로고
    • Muscle microdialysis as a model study to relate the drug concentration in tissue interstitial fluid and dialysate
    • Y. Deguchi, T. Terasaki, S. Kawasaki, and A. Tsuji. Muscle microdialysis as a model study to relate the drug concentration in tissue interstitial fluid and dialysate. J. Pharmacobio-Dyn. 14:483-492 (1991).
    • (1991) J. Pharmacobio-Dyn. , vol.14 , pp. 483-492
    • Deguchi, Y.1    Terasaki, T.2    Kawasaki, S.3    Tsuji, A.4
  • 11
    • 0025989174 scopus 로고
    • In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle. A microdialysis study
    • D. Deleu, S. Sarre, G. Ebinger, and Y. Michotte. In vivo pharmacokinetics of levodopa and 3-O-methyldopa in muscle. A microdialysis study. Naunyn-Schmied. Arch Pharmacol. 344:514-519 (1991).
    • (1991) Naunyn-Schmied. Arch Pharmacol. , vol.344 , pp. 514-519
    • Deleu, D.1    Sarre, S.2    Ebinger, G.3    Michotte, Y.4
  • 13
    • 0026625182 scopus 로고
    • Antipyrine as a dialyzable reference to correct differences in efficiency among and within sampling devices during in vivo microdialysis
    • R. A. Yokel, D. D. Allen, D. E. Burgio, and P. J. McNamara. Antipyrine as a dialyzable reference to correct differences in efficiency among and within sampling devices during in vivo microdialysis. J. Pharmacol. Toxicol. Meth. 27:135-142 (1992).
    • (1992) J. Pharmacol. Toxicol. Meth. , vol.27 , pp. 135-142
    • Yokel, R.A.1    Allen, D.D.2    Burgio, D.E.3    McNamara, P.J.4
  • 15
    • 0023627577 scopus 로고
    • A microdialysis method allowing characterization of intercellular water space in humans
    • P. Lonnroth, P. A. Jansson, and U. Smith. A microdialysis method allowing characterization of intercellular water space in humans. Am. J. Physiol. 253:E228-E231 (1987).
    • (1987) Am. J. Physiol. , vol.253
    • Lonnroth, P.1    Jansson, P.A.2    Smith, U.3
  • 16
    • 0025334552 scopus 로고
    • Interstitial glycerol concentration measured by microdialysis in two subcutaneous regions in humans
    • P. A. Jansson, U. Smith, and P. Lonnroth. Interstitial glycerol concentration measured by microdialysis in two subcutaneous regions in humans. Am. J. Physiol. 258:E918-E922 (1990).
    • (1990) Am. J. Physiol. , vol.258
    • Jansson, P.A.1    Smith, U.2    Lonnroth, P.3
  • 17
    • 0025013081 scopus 로고
    • Microdialysis sampling for determination of plasma protein binding of drugs
    • A. M. Herrera, D. O. Scott, and C. E. Lunte. Microdialysis sampling for determination of plasma protein binding of drugs. Pharm. Res. 7:1077-1081 (1990).
    • (1990) Pharm. Res. , vol.7 , pp. 1077-1081
    • Herrera, A.M.1    Scott, D.O.2    Lunte, C.E.3
  • 18
    • 0006469116 scopus 로고
    • In vitro microdialysis study of the thermodynamics of cyclosporin A binding to components of human plasma
    • W. F. Elmquist and H. Yang. In vitro microdialysis study of the thermodynamics of cyclosporin A binding to components of human plasma. Curr. Sep. 12:54 (1993).
    • (1993) Curr. Sep. , vol.12 , pp. 54
    • Elmquist, W.F.1    Yang, H.2
  • 19
    • 0019731754 scopus 로고
    • Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum
    • Lond.
    • C. Nicholson and J. M. Phillips. Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum. J. Physiol. (Lond.) 321:225-257 (1981).
    • (1981) J. Physiol. , vol.321 , pp. 225-257
    • Nicholson, C.1    Phillips, J.M.2
  • 20
    • 0024414347 scopus 로고
    • Intracerebral microdialysis. II. Mathematical studies of diffusion kinetics
    • G. Amberg and N. Lindefors. Intracerebral microdialysis. II. Mathematical studies of diffusion kinetics. J. Pharmacol. Meth. 22:157-183 (1989).
    • (1989) J. Pharmacol. Meth. , vol.22 , pp. 157-183
    • Amberg, G.1    Lindefors, N.2
  • 21
    • 0024343821 scopus 로고
    • Intracerebral microdialysis. I. Experimental studies of diffusion kinetics
    • N. Lindefors, G. Amberg, and U. Ungerstedt. Intracerebral microdialysis. I. Experimental studies of diffusion kinetics. J. Pharmacol. Meth. 22:141-156 (1989).
    • (1989) J. Pharmacol. Meth. , vol.22 , pp. 141-156
    • Lindefors, N.1    Amberg, G.2    Ungerstedt, U.3
  • 22
    • 0025044931 scopus 로고
    • Microdialysis: Theory and application
    • H. Benveniste and P. C. Huttemeier. Microdialysis: theory and application. Prog. Neurobiol 35:195-215 (1990).
    • (1990) Prog. Neurobiol , vol.35 , pp. 195-215
    • Benveniste, H.1    Huttemeier, P.C.2
  • 23
    • 0025051997 scopus 로고
    • Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro
    • P. M. Bungay, P. F. Morrison, and R. L. Dedrick. Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitro. Life Sci. 46:105-119 (1990).
    • (1990) Life Sci. , vol.46 , pp. 105-119
    • Bungay, P.M.1    Morrison, P.F.2    Dedrick, R.L.3
  • 24
    • 85023518792 scopus 로고
    • The use of microdialysis in pharmacokinetics and pharmacodynamics
    • T. E. Robinson and J. B. Justice, Jr. (Eds.), Elsevier, Amsterdam
    • L. Stahle. The use of microdialysis in pharmacokinetics and pharmacodynamics. In: T. E. Robinson and J. B. Justice, Jr. (Eds.), Microdialysis in the Neurosciences, Techniques in the Behavioral and Neural Sciences, Vol. 7, Elsevier, Amsterdam, pp. 155-174 (1991).
    • (1991) Microdialysis in the Neurosciences, Techniques in the Behavioral and Neural Sciences , vol.7 , pp. 155-174
    • Stahle, L.1
  • 28
    • 0027244155 scopus 로고
    • A survey on quantitative microdialysis: Theoretical models and practical implications
    • J. Kehr. A survey on quantitative microdialysis: theoretical models and practical implications. J. Neurosci. Meth. 48:251-261 (1993).
    • (1993) J. Neurosci. Meth. , vol.48 , pp. 251-261
    • Kehr, J.1
  • 30
    • 0027382432 scopus 로고
    • Microdialysis calibration using retrodialysis and zero-net flux: Application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus
    • Y. Wang, S. L. Wong, and R. J. Sawchuk. Microdialysis calibration using retrodialysis and zero-net flux: application to a study of the distribution of zidovudine to rabbit cerebrospinal fluid and thalamus. Pharm. Res. 10:1411-1419 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 1411-1419
    • Wang, Y.1    Wong, S.L.2    Sawchuk, R.J.3
  • 31
    • 0022404730 scopus 로고
    • Mass transfer in brain dialysis devices: A new method for estimation of extracellular amino acids concentration
    • I. Jacobson, M. Sandberg, and A. Hamberger. Mass transfer in brain dialysis devices: a new method for estimation of extracellular amino acids concentration. J. Neurosci. Meth. 15:263-268 (1985).
    • (1985) J. Neurosci. Meth. , vol.15 , pp. 263-268
    • Jacobson, I.1    Sandberg, M.2    Hamberger, A.3
  • 32
    • 0025804750 scopus 로고
    • A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis
    • L. Stahle, S. Segersvard, and U. Ungerstedt. A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis. J. Pharmacol. Meth. 25:41-52 (1990).
    • (1990) J. Pharmacol. Meth. , vol.25 , pp. 41-52
    • Stahle, L.1    Segersvard, S.2    Ungerstedt, U.3
  • 33
    • 0024324218 scopus 로고
    • Brain microdialysis
    • H. Benveniste. Brain microdialysis. J. Neurochem. 52:1667-179 (1989).
    • (1989) J. Neurochem. , vol.52 , pp. 1667-2179
    • Benveniste, H.1
  • 34
    • 0006876340 scopus 로고
    • Comparison of in vitro and in vivo calibration of microdialysis probes using retrodialysis
    • Y. Wang, S. L. Wong, and R. J. Sawchuk. Comparison of in vitro and in vivo calibration of microdialysis probes using retrodialysis. Curr. Sep. 10:87 (1991).
    • (1991) Curr. Sep. , vol.10 , pp. 87
    • Wang, Y.1    Wong, S.L.2    Sawchuk, R.J.3
  • 35
    • 0022750051 scopus 로고
    • Sampling considerations for on-line microbore liquid chromatography of brain dialysate
    • S. A. Wages, W. H. Church, and J. B. Justice. Sampling considerations for on-line microbore liquid chromatography of brain dialysate. Anal. Chem. 58:1649-1656 (1986).
    • (1986) Anal. Chem. , vol.58 , pp. 1649-1656
    • Wages, S.A.1    Church, W.H.2    Justice, J.B.3
  • 36
    • 0024997055 scopus 로고
    • Optimization of LC apparatus for determinations in neurochemistry with an emphasis on microdialysis samples. J
    • P. T. Kissinger and R. E. Shoup. Optimization of LC apparatus for determinations in neurochemistry with an emphasis on microdialysis samples. J Neurosci. Meth. 34:3-10 (1990).
    • (1990) Neurosci. Meth. , vol.34 , pp. 3-10
    • Kissinger, P.T.1    Shoup, R.E.2
  • 37
    • 0025141788 scopus 로고
    • On-line analysis of penicillin blood levels in the live rat by combined microdialysis/fast-atom bombardment mass spectroscopy
    • R. M. Caprioli and S. N. Lin. On-line analysis of penicillin blood levels in the live rat by combined microdialysis/fast-atom bombardment mass spectroscopy. Proc. Natl. Acad. Sci. 87:240-243 (1990).
    • (1990) Proc. Natl. Acad. Sci. , vol.87 , pp. 240-243
    • Caprioli, R.M.1    Lin, S.N.2
  • 38
    • 0029246591 scopus 로고
    • Continuous in vivo monitoring of amino acid neurotransmitters by microdialysis sampling with on-line derivatization and capillary electrophoresis separation
    • S. Y. Zhou, H. Zuo, J. F. Stobaugh, C. E. Lunte, and S. M. Lunte. Continuous in vivo monitoring of amino acid neurotransmitters by microdialysis sampling with on-line derivatization and capillary electrophoresis separation. Anal. Chem. 67:584-599 (1995).
    • (1995) Anal. Chem. , vol.67 , pp. 584-599
    • Zhou, S.Y.1    Zuo, H.2    Stobaugh, J.F.3    Lunte, C.E.4    Lunte, S.M.5
  • 39
    • 0026388158 scopus 로고
    • RIA-linked microdialysis sampling in the awake rat: Application to free-drug pharmacokinetics of hydrocortisone
    • M. A. Miller and R. S. Geary. RIA-linked microdialysis sampling in the awake rat: application to free-drug pharmacokinetics of hydrocortisone. J. Pharm. Biomed. Anal. 9:901-910 (1991).
    • (1991) J. Pharm. Biomed. Anal. , vol.9 , pp. 901-910
    • Miller, M.A.1    Geary, R.S.2
  • 40
    • 0028959182 scopus 로고
    • Microdialysis sampling coupled to on-line microbore liquid chromatography for pharmacokinetic studies
    • K. M. Steele and C. E. Lunte. Microdialysis sampling coupled to on-line microbore liquid chromatography for pharmacokinetic studies. J. Pharm. Biomed. Anal. 13:149-154 (1995).
    • (1995) J. Pharm. Biomed. Anal. , vol.13 , pp. 149-154
    • Steele, K.M.1    Lunte, C.E.2
  • 41
    • 0028890141 scopus 로고
    • Microdialysis sampling coupled on-line to fast microbore liquid chromatography
    • A. Chen and C. E. Lunte. Microdialysis sampling coupled on-line to fast microbore liquid chromatography. J. Chromatogr. A 691:29-35 (1995).
    • (1995) J. Chromatogr. A , vol.691 , pp. 29-35
    • Chen, A.1    Lunte, C.E.2
  • 42
    • 0025004770 scopus 로고
    • Electrochemical detection, HPLC and in vivo monitoring in the biosciences
    • C. A. Marsden, I. A. Macdonald, M. H. Joseph, and D. Perrett. Electrochemical detection, HPLC and in vivo monitoring in the biosciences. J. Neurosci. Meth. 34:1-2 (1990).
    • (1990) J. Neurosci. Meth. , vol.34 , pp. 1-2
    • Marsden, C.A.1    Macdonald, I.A.2    Joseph, M.H.3    Perrett, D.4
  • 43
    • 0027205384 scopus 로고
    • Determination of dopamine and its metabolites in microdialysates by capillary liquid chromatography with electrochemical detection
    • V. F. Ruban. Determination of dopamine and its metabolites in microdialysates by capillary liquid chromatography with electrochemical detection. J. Chromatog. 619:11-115 (1993).
    • (1993) J. Chromatog. , vol.619 , pp. 11-115
    • Ruban, V.F.1
  • 44
    • 0028944630 scopus 로고
    • High-performance liquid chromatographic analysis with electrochemical detection of biogenic amines using microbore columns
    • F. C. Cheng and J. S. Kuo. High-performance liquid chromatographic analysis with electrochemical detection of biogenic amines using microbore columns. J. Chromatog. B 665:1-13 (1995).
    • (1995) J. Chromatog. B , vol.665 , pp. 1-13
    • Cheng, F.C.1    Kuo, J.S.2
  • 45
    • 0027288111 scopus 로고
    • Simultaneous measurement of monoamines, metabolites and amino acids in brain tissue and microdialysis perfusates
    • P. Gamache, E. Ryan, C. Svendsen, K. Murayama, and I. N. Acworth. Simultaneous measurement of monoamines, metabolites and amino acids in brain tissue and microdialysis perfusates. J. Chromatog. 614:213-220 (1993).
    • (1993) J. Chromatog. , vol.614 , pp. 213-220
    • Gamache, P.1    Ryan, E.2    Svendsen, C.3    Murayama, K.4    Acworth, I.N.5
  • 46
    • 0028290952 scopus 로고
    • Liquid chromatographic determination of tacrine and its metabolites in rat bile microdialysates
    • M. E. Hadwiger, M. Telting-Diaz, and C. E. Lunte. Liquid chromatographic determination of tacrine and its metabolites in rat bile microdialysates. J. Chromatog. B 655:235-241 (1994).
    • (1994) J. Chromatog. B , vol.655 , pp. 235-241
    • Hadwiger, M.E.1    Telting-Diaz, M.2    Lunte, C.E.3
  • 47
    • 0027935610 scopus 로고
    • Investigation of the distribution of EAB 515 to cortical ECF and CSF in freely moving rats utilizing microdialysis
    • B. K. Malhotra, M. Lemaire, and R. J. Sawchuk. Investigation of the distribution of EAB 515 to cortical ECF and CSF in freely moving rats utilizing microdialysis. Pharm. Res. 11:1223-1232 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 1223-1232
    • Malhotra, B.K.1    Lemaire, M.2    Sawchuk, R.J.3
  • 48
    • 0027769788 scopus 로고
    • Distributional transport kinetics of zidovudine between plasma and brain extracellular fluid/cerebrospinal fluid in the rabbit: Investigation of the inhibitory effect of probenecid utilizing microdialysis
    • S. L. Wong, K. van Belle, and R. J. Sawchuk. Distributional transport kinetics of zidovudine between plasma and brain extracellular fluid/cerebrospinal fluid in the rabbit: Investigation of the inhibitory effect of probenecid utilizing microdialysis. J. Pharmacol. Exp. Ther. 264:899-909 (1993).
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 899-909
    • Wong, S.L.1    Van Belle, K.2    Sawchuk, R.J.3
  • 49
    • 0025314801 scopus 로고
    • In vivo microdialysis sampling coupled to liquid chromatography for the study of acetaminophen metabolism
    • D. O. Scott, L. R. Sorensen, and C. E. Lunte. In vivo microdialysis sampling coupled to liquid chromatography for the study of acetaminophen metabolism. J. Chromatog. 506:461-469 (1990).
    • (1990) J. Chromatog. , vol.506 , pp. 461-469
    • Scott, D.O.1    Sorensen, L.R.2    Lunte, C.E.3
  • 50
    • 0026698233 scopus 로고
    • Coupling microdialysis with capillary electrophoresis: A new approach to the study of drug transfer between two compartments of the body in freely moving rats
    • S. Tellez, N. Forges, A. Roussin, and L. Hernandez. Coupling microdialysis with capillary electrophoresis: a new approach to the study of drug transfer between two compartments of the body in freely moving rats. J. Chromatog. 581:257-266 (1992).
    • (1992) J. Chromatog. , vol.581 , pp. 257-266
    • Tellez, S.1    Forges, N.2    Roussin, A.3    Hernandez, L.4
  • 51
    • 0028399721 scopus 로고
    • On-line coupling of in vivo microdialysis sampling with capillary electrophoresis
    • B. L. Hogan, S. M. Lunte, J. F. Stobaugh, and C. E. Lunte. On-line coupling of in vivo microdialysis sampling with capillary electrophoresis. Anal. Chem. 66:596-602 (1994).
    • (1994) Anal. Chem. , vol.66 , pp. 596-602
    • Hogan, B.L.1    Lunte, S.M.2    Stobaugh, J.F.3    Lunte, C.E.4
  • 52
    • 0025322564 scopus 로고
    • In vivo microdialysis and thermospray tandem mass spectroscopy of the dopamine uptake blocker 1[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)-piper azine (GBR-12909)
    • S. D. Menacherry and J. B. Justice. In vivo microdialysis and thermospray tandem mass spectroscopy of the dopamine uptake blocker 1[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)-piper azine (GBR-12909). Anal. Chem. 62:597-601 (1990).
    • (1990) Anal. Chem. , vol.62 , pp. 597-601
    • Menacherry, S.D.1    Justice, J.B.2
  • 53
    • 0028469349 scopus 로고
    • An automated liquid chromatography/mass spectrometry system coupled on-line with microdialysis for the in vivo analysis of contrast agents
    • P. Michelsen and G. Petterssen. An automated liquid chromatography/mass spectrometry system coupled on-line with microdialysis for the in vivo analysis of contrast agents. Rapid Commun. Mass Spectrom. 8:517-520 (1994).
    • (1994) Rapid Commun. Mass Spectrom. , vol.8 , pp. 517-520
    • Michelsen, P.1    Petterssen, G.2
  • 54
    • 0026955486 scopus 로고
    • On-line coupling of in vivo microdialysis with tandem mass spectrometry
    • L. J. Deterding, K. Dix, L. T. Burka, and K. B. Tomer. On-line coupling of in vivo microdialysis with tandem mass spectrometry. Anal. Chem. 64:2636-2641 (1992).
    • (1992) Anal. Chem. , vol.64 , pp. 2636-2641
    • Deterding, L.J.1    Dix, K.2    Burka, L.T.3    Tomer, K.B.4
  • 55
    • 0027943234 scopus 로고
    • Tris(2-chloroethyl) phosphate pharmacokinetics in the fischer 344 rat: A comparison of conventional methods and in vivo microdialysis coupled with tandem mass spectrometry
    • K. Dix, L. J. Deterding, L. T. Burka, and K. B. Tomer. Tris(2-chloroethyl) phosphate pharmacokinetics in the fischer 344 rat: a comparison of conventional methods and in vivo microdialysis coupled with tandem mass spectrometry. J. Pharm. Sci. 83:1622-1629 (1994).
    • (1994) J. Pharm. Sci. , vol.83 , pp. 1622-1629
    • Dix, K.1    Deterding, L.J.2    Burka, L.T.3    Tomer, K.B.4
  • 56
    • 0028893213 scopus 로고
    • Detection of gamma-aminobutyric acid in a living rat brain using in vivo microdialysis-capillary electrophoresis/mass spectrometry
    • Y. Takada, M. Yoshida, M. Sakairi, and H. Koizumi. Detection of gamma-aminobutyric acid in a living rat brain using in vivo microdialysis-capillary electrophoresis/mass spectrometry. Rapid Commun. Mass Spectrom. 9:895-896 (1995).
    • (1995) Rapid Commun. Mass Spectrom. , vol.9 , pp. 895-896
    • Takada, Y.1    Yoshida, M.2    Sakairi, M.3    Koizumi, H.4
  • 57
    • 0000397233 scopus 로고
    • The feasibility of repeated microdialysis for within-subjects design experiment: Studies on the mesostriatal dopamine system
    • T. E. Robinson and J. B. Justice, Jr. (eds) Elsevier
    • T. E. Robinson and D. M. Camp. The feasibility of repeated microdialysis for within-subjects design experiment: studies on the mesostriatal dopamine system. in Microdialysis in the Neurosciences, T. E. Robinson and J. B. Justice, Jr. (eds) Elsevier, 1991.
    • (1991) Microdialysis in the Neurosciences
    • Robinson, T.E.1    Camp, D.M.2
  • 58
    • 0029013672 scopus 로고
    • Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion
    • Y. Wang and R. J. Sawchuk. Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion. J. Pharm. Sci. 84:871-876 (1995).
    • (1995) J. Pharm. Sci. , vol.84 , pp. 871-876
    • Wang, Y.1    Sawchuk, R.J.2
  • 59
    • 0028998552 scopus 로고
    • Effect of the P-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: An in vivo microdialysis study in freely-moving rats
    • Q. Wang, H. Yang, D. W. Miller, and W. F. Elmquist. Effect of the P-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: An in vivo microdialysis study in freely-moving rats. Biochem. Biophys. Res. Commun. 211:719-726 (1995).
    • (1995) Biochem. Biophys. Res. Commun. , vol.211 , pp. 719-726
    • Wang, Q.1    Yang, H.2    Miller, D.W.3    Elmquist, W.F.4
  • 60
    • 0028153040 scopus 로고
    • Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain
    • E. C. M. de Lange, M. Danhof, A. G. de Boer, and D. D. Breimer. Critical factors of intracerebral microdialysis as a technique to determine the pharmacokinetics of drugs in rat brain. Brain Res. 666:1-8 (1994).
    • (1994) Brain Res. , vol.666 , pp. 1-8
    • De Lange, E.C.M.1    Danhof, M.2    De Boer, A.G.3    Breimer, D.D.4
  • 61
    • 0027524422 scopus 로고
    • Tissue and microdialysate changes after repeated and permanent probe implantation in the striatum of freely moving rats
    • J. Georgieva, J. Luthman, B. Mohringe, and O. Magnusson. Tissue and microdialysate changes after repeated and permanent probe implantation in the striatum of freely moving rats. Brain Res. Bull. 31:463-470 (1993).
    • (1993) Brain Res. Bull. , vol.31 , pp. 463-470
    • Georgieva, J.1    Luthman, J.2    Mohringe, B.3    Magnusson, O.4
  • 62
    • 0023266728 scopus 로고
    • Cellular reactions to implantation of a microdialysis tube in the rat hippocampus
    • H. Benveniste and N. H. Diemer. Cellular reactions to implantation of a microdialysis tube in the rat hippocampus. Acta Neuropathol. 74:234-238 (1987).
    • (1987) Acta Neuropathol. , vol.74 , pp. 234-238
    • Benveniste, H.1    Diemer, N.H.2
  • 63
    • 0025034796 scopus 로고
    • Brain eicosanoid formation following acute penetration injury as studied by in vivo microdialysis
    • J. A. Yergey and M. P. Heyes. Brain eicosanoid formation following acute penetration injury as studied by in vivo microdialysis. J. Cereb. Blood Flow Metab. 10:143-146 (1990).
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 143-146
    • Yergey, J.A.1    Heyes, M.P.2
  • 64
    • 0023406490 scopus 로고
    • Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fiber through the dorsal hippocampus in the rat
    • H. Benveniste, J. Drejer, A. Schousboe, and N. H. Diemer. Regional cerebral glucose phosphorylation and blood flow after insertion of a microdialysis fiber through the dorsal hippocampus in the rat. J. Neurochem. 49:729-734 (1987).
    • (1987) J. Neurochem. , vol.49 , pp. 729-734
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 65
    • 0026720437 scopus 로고
    • On the use of multiple probe insertions at the same site for repeated intracerebral microdialysis experiments in the nigrostriatal dopamine system of rats
    • D. M. Camp and T. E. Robinson. On the use of multiple probe insertions at the same site for repeated intracerebral microdialysis experiments in the nigrostriatal dopamine system of rats. J. Neurochem. 58:1706-1715 (1992).
    • (1992) J. Neurochem. , vol.58 , pp. 1706-1715
    • Camp, D.M.1    Robinson, T.E.2
  • 66
    • 0027043291 scopus 로고
    • 4-trimethylammonium antipyrine: A quaternary ammonium nonradionuclide marker for blood-brain barrier integrity during in vivo microdialysis
    • D. D. Allen, P. A. Crooks, and R. A. Yokel. 4-trimethylammonium antipyrine: A quaternary ammonium nonradionuclide marker for blood-brain barrier integrity during in vivo microdialysis. J. Pharmacol. Tox. Methods. 28:129-135 (1992).
    • (1992) J. Pharmacol. Tox. Methods. , vol.28 , pp. 129-135
    • Allen, D.D.1    Crooks, P.A.2    Yokel, R.A.3
  • 67
    • 0022470850 scopus 로고
    • Microdialysis in the study of extracellular levels of amino acids in the rat brain
    • U. Tossman and U. Ungerstedt. Microdialysis in the study of extracellular levels of amino acids in the rat brain. Acta Physiol. Scand. 128:9-14 (1986).
    • (1986) Acta Physiol. Scand. , vol.128 , pp. 9-14
    • Tossman, U.1    Ungerstedt, U.2
  • 68
    • 0028825450 scopus 로고
    • Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling
    • T. A. Aasmundstad, J. Morland, and R. E. Paulsen. Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling. J. Pharmacal. Exper. Ther. 275:435-441 (1995).
    • (1995) J. Pharmacal. Exper. Ther. , vol.275 , pp. 435-441
    • Aasmundstad, T.A.1    Morland, J.2    Paulsen, R.E.3
  • 69
    • 0026525408 scopus 로고
    • Determination of in vivo steady-state unbound drug concentration in the brain interstitial fluid by microdialysis
    • T. Terasaki, Y. Deguchi, Y. Kasama, W. M. Pardridge, and A. Tsuji. Determination of in vivo steady-state unbound drug concentration in the brain interstitial fluid by microdialysis. Int. J. Pharmaceut. 81:143-152 (1992).
    • (1992) Int. J. Pharmaceut. , vol.81 , pp. 143-152
    • Terasaki, T.1    Deguchi, Y.2    Kasama, Y.3    Pardridge, W.M.4    Tsuji, A.5
  • 70
    • 0017210792 scopus 로고
    • The application of brain capillary permeability coefficient measurements to pathological conditions and the selection of agents which cross the blood-brain barrier
    • V. A. Levin, H. D. Landahl, and M. A. Freeman-Dove. The application of brain capillary permeability coefficient measurements to pathological conditions and the selection of agents which cross the blood-brain barrier. J. Pharmacokinet. Biopharm. 4:499-519 (1976).
    • (1976) J. Pharmacokinet. Biopharm. , vol.4 , pp. 499-519
    • Levin, V.A.1    Landahl, H.D.2    Freeman-Dove, M.A.3
  • 71
    • 0344582183 scopus 로고
    • Effect of interleukin-2 on the blood brain barrier: An in vivo microdialysis study
    • M. Fontaine, Q. Wang, H. Yang, and W. F. Elmquist. Effect of interleukin-2 on the blood brain barrier: An in vivo microdialysis study. Pharm. Res. 12:S-406 (1995).
    • (1995) Pharm. Res. , vol.12
    • Fontaine, M.1    Wang, Q.2    Yang, H.3    Elmquist, W.F.4
  • 74
    • 0030435368 scopus 로고    scopus 로고
    • Quantitative assessment of blood-brain barrier damage during microdialysis
    • M. E. Morgan, D. Singhal, and B. D. Anderson. Quantitative assessment of blood-brain barrier damage during microdialysis. J. Pharmacol. Exper. Ther. 277:1167-1176 (1996).
    • (1996) J. Pharmacol. Exper. Ther. , vol.277 , pp. 1167-1176
    • Morgan, M.E.1    Singhal, D.2    Anderson, B.D.3
  • 75
    • 0027982389 scopus 로고
    • Quantitative approaches to in vivo brain microdialysis
    • L. H. Parsons and J. B. Justice. Quantitative approaches to in vivo brain microdialysis. Crit. Reviews in Neurobiology 8:189-220 (1994).
    • (1994) Crit. Reviews in Neurobiology , vol.8 , pp. 189-220
    • Parsons, L.H.1    Justice, J.B.2
  • 76
    • 0025827888 scopus 로고
    • In vivo transport of a dynorphin-like analgesic peptide, E-2078, through the blood-brain barrier: An application of brain microdialysis
    • T. Terasaki Y. Deguchi H. Sato, K. Hirai, and A. Tsuji. In vivo transport of a dynorphin-like analgesic peptide, E-2078, through the blood-brain barrier: An application of brain microdialysis. Pharm. Res. 8:815-820 (1991).
    • (1991) Pharm. Res. , vol.8 , pp. 815-820
    • Terasaki, T.1    Deguchi, Y.2    Sato, H.3    Hirai, K.4    Tsuji, A.5
  • 77
    • 0028100091 scopus 로고
    • Application of microdialysis to the pharmacokinetics of analgesics: Problems with reduction of dialysis efficiency in vivo
    • C. Sauernheimer, K. M. Williams, K. Brune, and G. Geisslinger. Application of microdialysis to the pharmacokinetics of analgesics: problems with reduction of dialysis efficiency in vivo. J. Pharmacol. Toxicol. Methods 32:149-154 (1994).
    • (1994) J. Pharmacol. Toxicol. Methods , vol.32 , pp. 149-154
    • Sauernheimer, C.1    Williams, K.M.2    Brune, K.3    Geisslinger, G.4
  • 78
    • 0026635834 scopus 로고
    • Estimation of unbound concentrations of morphine from microdialysate concentrations by use of nonlinear regression analysis in vivo and in vitro during steady state conditions
    • M. Ekblom, M. Gardmark, and M. Hammarlund-Udenaes. Estimation of unbound concentrations of morphine from microdialysate concentrations by use of nonlinear regression analysis in vivo and in vitro during steady state conditions. Life Sciences 51:449-460 (1992).
    • (1992) Life Sciences , vol.51 , pp. 449-460
    • Ekblom, M.1    Gardmark, M.2    Hammarlund-Udenaes, M.3
  • 79
    • 0026643628 scopus 로고
    • Simultaneous measurement of extracellular morphine and serotonin in brain tissue and CSF by microdialysis in awake rats
    • F. F. Matos, H. Rollema, and A. I. Basbaum. Simultaneous measurement of extracellular morphine and serotonin in brain tissue and CSF by microdialysis in awake rats. J. Neurochem. 58:1773-1781 (1992).
    • (1992) J. Neurochem. , vol.58 , pp. 1773-1781
    • Matos, F.F.1    Rollema, H.2    Basbaum, A.I.3
  • 80
    • 0029589460 scopus 로고
    • Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: A microdialysis study
    • M. J. Barjavel J-M. Scherrmann, and H. N. Bargava. Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: a microdialysis study. Brit. J. Pharmacol. 116:3205-3210 (1995).
    • (1995) Brit. J. Pharmacol. , vol.116 , pp. 3205-3210
    • Barjavel, M.J.1    Scherrmann, J.-M.2    Bargava, H.N.3
  • 81
    • 0029025920 scopus 로고
    • Analgesic response and plasma and brain extracellular fluid pharmacokinetics of morphine and morphine-6-,β-D-glucuronide in the rat
    • F. Stain, M. J. Barjavel, P. Sandouk, M. Plotkine, J-M. Scherrmann, and H. N. Bhargava. Analgesic response and plasma and brain extracellular fluid pharmacokinetics of morphine and morphine-6-,β-D-glucuronide in the rat. J. Pharmacol. Exper. Ther. 274:852-857 (1995).
    • (1995) J. Pharmacol. Exper. Ther. , vol.274 , pp. 852-857
    • Stain, F.1    Barjavel, M.J.2    Sandouk, P.3    Plotkine, M.4    Scherrmann, J.-M.5    Bhargava, H.N.6
  • 82
  • 83
    • 0028859488 scopus 로고
    • Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid of and cerebral extracellular space in awake rats by in vivo microdialysis
    • L. Granero, M. Santiago, J. Cano, A. Machado, and J-E. Peris. Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid of and cerebral extracellular space in awake rats by in vivo microdialysis. Antimicrob. Agents Chemother. 39:2728-2731 (1995).
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 2728-2731
    • Granero, L.1    Santiago, M.2    Cano, J.3    Machado, A.4    Peris, J.-E.5
  • 84
    • 0029910856 scopus 로고    scopus 로고
    • Fluconazole distribution to the brain: A crossover study in freely-moving rats using in vivo microdialysis
    • H. Yang, Q. Wang, and W. F. Elmquist. Fluconazole distribution to the brain: A crossover study in freely-moving rats using in vivo microdialysis. Pharm. Res. 13:1570-1575 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 1570-1575
    • Yang, H.1    Wang, Q.2    Elmquist, W.F.3
  • 85
    • 0024953619 scopus 로고
    • Effect of probenecid on the renal and nonrenal clearances of zidovudine and its distribution to the cerebrospinal fluid of the rabbit
    • M. A. Hedaya and R. J. Sawchuk. Effect of probenecid on the renal and nonrenal clearances of zidovudine and its distribution to the cerebrospinal fluid of the rabbit. J. Pharm. Sci. 78:716-722 (1989).
    • (1989) J. Pharm. Sci. , vol.78 , pp. 716-722
    • Hedaya, M.A.1    Sawchuk, R.J.2
  • 86
    • 0029013672 scopus 로고
    • Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion
    • Y. Wang and R. J. Sawchuk. Zidovudine transport in the rabbit brain during intravenous and intracerebroventricular infusion. J. Pharm. Sci. 84:871-876 (1995).
    • (1995) J. Pharm. Sci. , vol.84 , pp. 871-876
    • Wang, Y.1    Sawchuk, R.J.2
  • 87
    • 0026474639 scopus 로고
    • Penetration of zidovudine and 3′fluoro-3′-deoxythymidine into the brain, muscle tissue, and veins in Cynomolgus monkeys: Relation to antiviral action
    • E. Ljungdahl-Stahle, E. Guzenda, D. Bottiger, B. Wahren, B. Oberg, and L. Stahle. Penetration of zidovudine and 3′fluoro-3′-deoxythymidine into the brain, muscle tissue, and veins in Cynomolgus monkeys: relation to antiviral action. Antimicrob. Agents Chemother. 36:2418-2422 (1992).
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 2418-2422
    • Ljungdahl-Stahle, E.1    Guzenda, E.2    Bottiger, D.3    Wahren, B.4    Oberg, B.5    Stahle, L.6
  • 88
    • 0026528884 scopus 로고
    • Pharmacokinetics and distribution over the blood-brain barrier of two acyclic guanosine analogs in rats, studied by microdialysis
    • L. Stahle, and B. Oberg. Pharmacokinetics and distribution over the blood-brain barrier of two acyclic guanosine analogs in rats, studied by microdialysis. Antimicrob. Agents Chemother. 36:339-342 (1992).
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 339-342
    • Stahle, L.1    Oberg, B.2
  • 89
    • 0029619438 scopus 로고
    • The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain
    • E. C. M. de Lange, J. D. de Vries, C. Zurcher, M. Danhof, A. G. de Boer, and D. D. Breimer. The use of intracerebral microdialysis for the determination of pharmacokinetic profiles of anticancer drugs in tumor-bearing rat brain. Pharm. Res. 12:1924-1931 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 1924-1931
    • De Lange, E.C.M.1    De Vries, J.D.2    Zurcher, C.3    Danhof, M.4    De Boer, A.G.5    Breimer, D.D.6
  • 90
    • 0029838343 scopus 로고    scopus 로고
    • In vivo microdialysis to characterize drug transport in brain tumors: Analysis of methotrexate uptake in rat glioma-2 (RG-2) bearing rats
    • in press
    • D. Devineni, A. Klein-Szanto, and J. M. Gallo. In vivo microdialysis to characterize drug transport in brain tumors: analysis of methotrexate uptake in rat glioma-2 (RG-2) bearing rats, in press, Cancer Chemother. Pharmacol.
    • Cancer Chemother. Pharmacol.
    • Devineni, D.1    Klein-Szanto, A.2    Gallo, J.M.3
  • 91
    • 0029875694 scopus 로고    scopus 로고
    • Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470
    • D. Devineni, A. Klein-Szanto, and J. M. Gallo. Uptake of temozolomide in a rat glioma model in the presence and absence of the angiogenesis inhibitor TNP-470. Cancer Res. 56:1983-1987 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 1983-1987
    • Devineni, D.1    Klein-Szanto, A.2    Gallo, J.M.3
  • 92
    • 0027998226 scopus 로고
    • In vivo evidence for ATP-dependent and P-glycoprotein mediated transport of cyclosporin A at the blood-brain barrier
    • A. Sakata, I. Tamai, K. Kawazu, Y. Deguchi, T. Ohnishi, A. Saheki, and A. Tsuji. In vivo evidence for ATP-dependent and P-glycoprotein mediated transport of cyclosporin A at the blood-brain barrier. Biochem. Pharmacol. 48:1989-1992 (1994).
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1989-1992
    • Sakata, A.1    Tamai, I.2    Kawazu, K.3    Deguchi, Y.4    Ohnishi, T.5    Saheki, A.6    Tsuji, A.7
  • 93
    • 0029940587 scopus 로고    scopus 로고
    • Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis
    • D. E. Burgio, M. P. Gosland, and P. J. McNamara. Modulation effects of cyclosporine on etoposide pharmacokinetics and CNS distribution in the rat utilizing microdialysis. Biochem. Pharmacol. 51:987-992 (1996).
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 987-992
    • Burgio, D.E.1    Gosland, M.P.2    McNamara, P.J.3
  • 94
    • 0028146558 scopus 로고
    • Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis
    • R. D. Scheyer, M. J. During, D. D. Spencer, J. A. Cramer, and R. H. Mattson. Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis. Neurology 44:1469-1472 (1994).
    • (1994) Neurology , vol.44 , pp. 1469-1472
    • Scheyer, R.D.1    During, M.J.2    Spencer, D.D.3    Cramer, J.A.4    Mattson, R.H.5
  • 96
    • 0030043508 scopus 로고    scopus 로고
    • Monitoring free extracellular valproic acid by microdialysis in epileptic patients
    • L. Stahle, C. Alm, B. Ekquist, B. Lundquist, and T. Tomson. Monitoring free extracellular valproic acid by microdialysis in epileptic patients. Thera. Drug Monit. 18:14-18 (1996).
    • (1996) Thera. Drug Monit. , vol.18 , pp. 14-18
    • Stahle, L.1    Alm, C.2    Ekquist, B.3    Lundquist, B.4    Tomson, T.5
  • 97
    • 0026058001 scopus 로고
    • The extracellular concentration of the anti-epileptic drug valproate in the rat brain as determined with microdialysis and an automated HPLC procedure
    • J. H. Wolf, L. Veenma-Van der Duin, and J. Korf. The extracellular concentration of the anti-epileptic drug valproate in the rat brain as determined with microdialysis and an automated HPLC procedure. J. Pharm. Pharmacol. 43:101-106 (1991).
    • (1991) J. Pharm. Pharmacol. , vol.43 , pp. 101-106
    • Wolf, J.H.1    Veenma-Van Der Duin, L.2    Korf, J.3
  • 98
    • 0027131182 scopus 로고
    • Assessment of valproic acid serum-cerebrospinal fluid transport by microdialysis
    • P. L. Golden, K. R. Brouwer, and G. M. Pollack. Assessment of valproic acid serum-cerebrospinal fluid transport by microdialysis. Pharm. Res. 10:1765-1771 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 1765-1771
    • Golden, P.L.1    Brouwer, K.R.2    Pollack, G.M.3
  • 99
    • 0027723017 scopus 로고
    • Gabapentin anticonvulsant action in rats: Disequilibrium with peak drug concentrations in plasma and brain microdialysate
    • D. F. Welty, G. P. Schielke, M. G. Vartanian, and C. P. Taylor. Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate. Epilepsy Res. 16:175-181 (1993).
    • (1993) Epilepsy Res. , vol.16 , pp. 175-181
    • Welty, D.F.1    Schielke, G.P.2    Vartanian, M.G.3    Taylor, C.P.4
  • 100
    • 0029876793 scopus 로고    scopus 로고
    • The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach
    • Y. Wang and D. F. Welty. The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach. Pharm. Res. 13:398-403 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 398-403
    • Wang, Y.1    Welty, D.F.2
  • 101
    • 0029620811 scopus 로고
    • Study on brain interstitial fluid distribution and blood-brain barrier transport of baclofen in rats by microdialysis
    • Y. Deguchi, K. Inabe, K. Tomiyasu, K. Nozawa, S. Yamada, and R. Kimura. Study on brain interstitial fluid distribution and blood-brain barrier transport of baclofen in rats by microdialysis. Pharm. Res. 12:1838-1844 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 1838-1844
    • Deguchi, Y.1    Inabe, K.2    Tomiyasu, K.3    Nozawa, K.4    Yamada, S.5    Kimura, R.6
  • 102
    • 0027330285 scopus 로고
    • Carbamazepine and carbamazepine-10, 11-epoxide concentrations in rat brain and blood evaluated by in vivo microdialysis
    • R. Takanashi, M. Hagiwara, M. Watabe, R. Kan, and Y. Takahashi. Carbamazepine and carbamazepine-10, 11-epoxide concentrations in rat brain and blood evaluated by in vivo microdialysis. Jap. J. Psych. Neuro. 47:293-294 (1993).
    • (1993) Jap. J. Psych. Neuro. , vol.47 , pp. 293-294
    • Takanashi, R.1    Hagiwara, M.2    Watabe, M.3    Kan, R.4    Takahashi, Y.5
  • 103
    • 0028905671 scopus 로고
    • Brain, liver, and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: A quantitative microdialysis study
    • K. Van Belle, S. Sarre, G. Ebinger, and Y. Michotte. Brain, liver, and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study. J. Pharmacol. Exper. Ther. 272:1217-1222 (1995).
    • (1995) J. Pharmacol. Exper. Ther. , vol.272 , pp. 1217-1222
    • Van Belle, K.1    Sarre, S.2    Ebinger, G.3    Michotte, Y.4
  • 104
    • 0027507925 scopus 로고
    • In vitro and in vivo microdialysis calibration for the measurement of carbamazepine and its metabolites in rat brain tissue using the internal reference technique
    • K. Van Belle, T. Dzeka, S. Sarre, G. Ebinger, and Y. Michotte. In vitro and in vivo microdialysis calibration for the measurement of carbamazepine and its metabolites in rat brain tissue using the internal reference technique. J. Neurosci. Methods 49:167-173 (1993).
    • (1993) J. Neurosci. Methods , vol.49 , pp. 167-173
    • Van Belle, K.1    Dzeka, T.2    Sarre, S.3    Ebinger, G.4    Michotte, Y.5
  • 106
    • 0026091659 scopus 로고
    • Drug distribution studies with microdialysis: I. Tissue dependent difference in recovery between caffeine and theophylline
    • L. Stahle. Drug distribution studies with microdialysis: I. Tissue dependent difference in recovery between caffeine and theophylline. Life Sciences 49:1835-1842 (1991).
    • (1991) Life Sciences , vol.49 , pp. 1835-1842
    • Stahle, L.1
  • 107
    • 0026051504 scopus 로고
    • Drug distribution studies with microdialysis II. Caffeine and theophylline in blood, brain and other tissues in rats
    • L. Stahle, S. Segersvard, and U. Ungerstedt. Drug distribution studies with microdialysis II. Caffeine and theophylline in blood, brain and other tissues in rats. Life Sciences 49:1843-1852 (1991).
    • (1991) Life Sciences , vol.49 , pp. 1843-1852
    • Stahle, L.1    Segersvard, S.2    Ungerstedt, U.3
  • 108
    • 0026785056 scopus 로고
    • Application of microdialysis for study of caffeine distribution into brain and cerebrospinal fluid in rats
    • T. Nakazono, T. Murakami, S. Sakai, Y. Higashi, and N. Yata. Application of microdialysis for study of caffeine distribution into brain and cerebrospinal fluid in rats. Chem. Pharm. Bull. 40:2510-2515 (1992).
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 2510-2515
    • Nakazono, T.1    Murakami, T.2    Sakai, S.3    Higashi, Y.4    Yata, N.5
  • 109
    • 0025968046 scopus 로고
    • Aluminum distribution into brain and liver of rats and rabbits following intravenous aluminum lactate or citrate: A microdialysis study
    • R. A. Yokel, V. Lidums, P. J. McNamara, and U. Ungerstedt. Aluminum distribution into brain and liver of rats and rabbits following intravenous aluminum lactate or citrate: a microdialysis study. Toxicol. Appl. Pharmacol. 107:153-163 (1991).
    • (1991) Toxicol. Appl. Pharmacol. , vol.107 , pp. 153-163
    • Yokel, R.A.1    Lidums, V.2    McNamara, P.J.3    Ungerstedt, U.4
  • 110
    • 0025964344 scopus 로고
    • Aluminum mobilization by desferrioxamine assessed by microdialysis of the blood, liver and brain
    • R. A. Yokel, V. Lidums, and U. Ungerstedt. Aluminum mobilization by desferrioxamine assessed by microdialysis of the blood, liver and brain. Toxicology 66:313-324 (1991).
    • (1991) Toxicology , vol.66 , pp. 313-324
    • Yokel, R.A.1    Lidums, V.2    Ungerstedt, U.3
  • 111
    • 0028916272 scopus 로고
    • Evidence for energy-dependent transport of aluminum out of brain extracellular fluid
    • D. D. Allen, C. Orvig, and R. A. Yokel. Evidence for energy-dependent transport of aluminum out of brain extracellular fluid. Toxicology 98:31-39 (1995).
    • (1995) Toxicology , vol.98 , pp. 31-39
    • Allen, D.D.1    Orvig, C.2    Yokel, R.A.3
  • 112
    • 0027402636 scopus 로고
    • Distribution of tacrine across the blood-brain barrier in awake, freely moving rats using in vivo microdialysis sampling
    • M. Telting-Diaz and C. E. Lunte. Distribution of tacrine across the blood-brain barrier in awake, freely moving rats using in vivo microdialysis sampling. Pharm. Res. 10:44-48 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 44-48
    • Telting-Diaz, M.1    Lunte, C.E.2
  • 114
    • 0030431372 scopus 로고    scopus 로고
    • Effect of tacrine on in vivo release of dopamine and its metabolites in the striatum of freely moving rats
    • U. Warpman, X. Zhang, and A. Nordberg. Effect of tacrine on in vivo release of dopamine and its metabolites in the striatum of freely moving rats. J. Pharmacol. Exper. Ther. 277:917-922 (1996).
    • (1996) J. Pharmacol. Exper. Ther. , vol.277 , pp. 917-922
    • Warpman, U.1    Zhang, X.2    Nordberg, A.3
  • 115
    • 0028919353 scopus 로고
    • Microdialysis sampling to determine the pharmacokinetics of unbound SDZ-ICM 567 in blood and brain in awake, freely-moving rats
    • M. J. Alonso, A. Bruelisauer, P. Misslin, and M. Lemaire. Microdialysis sampling to determine the pharmacokinetics of unbound SDZ-ICM 567 in blood and brain in awake, freely-moving rats. Pharm. Res. 12:291-294 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 291-294
    • Alonso, M.J.1    Bruelisauer, A.2    Misslin, P.3    Lemaire, M.4
  • 116
    • 0028240660 scopus 로고
    • Measurement and pharmacokinetic analysis of imipramine and its metabolite by brain microdialysis
    • Y. Sato, S. Shibanoki, M. Sugahara, and K. Ishikawa. Measurement and pharmacokinetic analysis of imipramine and its metabolite by brain microdialysis. Br. J. Pharmacol. 112:625-629 (1994).
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 625-629
    • Sato, Y.1    Shibanoki, S.2    Sugahara, M.3    Ishikawa, K.4
  • 117
    • 0029973048 scopus 로고    scopus 로고
    • High-performance liquid chromatographic analysis of (s)-a-amino-5-phosphonomethly [1,1′-biphenyl]-3-propanoic acid (EAB 515) in brain and blood microdialysate (on-line) and in plasma ultrafiltrate of freely moving rats
    • B. K. Malhotra, M. Lemaire, J. F. Brouillard, and R. J. Sawchuk. High-performance liquid chromatographic analysis of (s)-a-amino-5-phosphonomethly [1,1′-biphenyl]-3-propanoic acid (EAB 515) in brain and blood microdialysate (on-line) and in plasma ultrafiltrate of freely moving rats. J. Chromatog. B. 679:167-176 (1996).
    • (1996) J. Chromatog. B. , vol.679 , pp. 167-176
    • Malhotra, B.K.1    Lemaire, M.2    Brouillard, J.F.3    Sawchuk, R.J.4
  • 118
    • 0031009743 scopus 로고    scopus 로고
    • Modeling the route of administration-based enhancement in the brain delivery of EAB 515, studied by microdialysis
    • in press
    • B. K. Malhotra, R. C. Brundage, M. Lemaire, and R. J. Sawchuk. Modeling the route of administration-based enhancement in the brain delivery of EAB 515, studied by microdialysis. J. Drug Targeting in press (1997).
    • (1997) J. Drug Targeting
    • Malhotra, B.K.1    Brundage, R.C.2    Lemaire, M.3    Sawchuk, R.J.4
  • 119
    • 0028815330 scopus 로고
    • The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics
    • E. C. M. de Lange, M. B. Hesselink, M. Danhof, A. G. de Boer, and D. D. Breimer. The use of intracerebral microdialysis to determine changes in blood-brain barrier transport characteristics. Pharm. Res. 12:129-133 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 129-133
    • De Lange, E.C.M.1    Hesselink, M.B.2    Danhof, M.3    De Boer, A.G.4    Breimer, D.D.5
  • 120
    • 0028787174 scopus 로고
    • Application of intracerebral microdialysis to study regional distribution kinetics of drugs in the rat brain
    • E. C. M. de Lange, M. R. Bouw, J. W. Mandema, M. Danhof, A. G. de Boer, and D. D. Breimer. Application of intracerebral microdialysis to study regional distribution kinetics of drugs in the rat brain. Brit. J. Pharmacol. 116:2538-2544 (1995).
    • (1995) Brit. J. Pharmacol. , vol.116 , pp. 2538-2544
    • De Lange, E.C.M.1    Bouw, M.R.2    Mandema, J.W.3    Danhof, M.4    De Boer, A.G.5    Breimer, D.D.6
  • 121
    • 0025992949 scopus 로고
    • Microdialysis of adipose tissue
    • P. Arner and J. Bolinder. Microdialysis of adipose tissue. J. Int. Med. 230:381-386 (1991).
    • (1991) J. Int. Med. , vol.230 , pp. 381-386
    • Arner, P.1    Bolinder, J.2
  • 122
    • 0028289885 scopus 로고
    • An improved method to calculate adipose tissue interstitial substrate recovery for microdialysis studies
    • P. A. Jansson, T. Veneman, N. Nurjhan, and J. Gerich. An improved method to calculate adipose tissue interstitial substrate recovery for microdialysis studies. Life Sci. 54:1621-1624 (1994).
    • (1994) Life Sci. , vol.54 , pp. 1621-1624
    • Jansson, P.A.1    Veneman, T.2    Nurjhan, N.3    Gerich, J.4
  • 123
    • 0027413886 scopus 로고
    • Pharmacokinetic monitoring in subcutaneous tissue using in vivo capillary ultrafiltration probes
    • M. C. Linhares and P. T. Kissinger. Pharmacokinetic monitoring in subcutaneous tissue using in vivo capillary ultrafiltration probes. Pharm. Res. 10:598-602 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 598-602
    • Linhares, M.C.1    Kissinger, P.T.2
  • 124
    • 0028228064 scopus 로고
    • Pharmacokinetic studies using microdialysis probes in subcutaneous tissue: Effects of the coadministration of ethanol and acetaminophen
    • M. C. Linhares and P. T. Kissinger. Pharmacokinetic studies using microdialysis probes in subcutaneous tissue: effects of the coadministration of ethanol and acetaminophen. J Pharm. Biomed. Anal. 12:619-627 (1994).
    • (1994) J Pharm. Biomed. Anal. , vol.12 , pp. 619-627
    • Linhares, M.C.1    Kissinger, P.T.2
  • 125
    • 0028300712 scopus 로고
    • Application of in vivo microdialysis to transdermal absorption of methotrexate in rats
    • K. Matsuyama, M. Nakashima, Y. Nakaboh, M. Ichikawa, T. Yano, and S. Satoh. Application of in vivo microdialysis to transdermal absorption of methotrexate in rats. Pharm. Res. 11:684-686 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 684-686
    • Matsuyama, K.1    Nakashima, M.2    Nakaboh, Y.3    Ichikawa, M.4    Yano, T.5    Satoh, S.6
  • 127
    • 0026788568 scopus 로고
    • Microdialysis sampling for the investigation of dermal drug transport
    • J. M. Ault, C. E. Lunte, N. M. Meltzer, and C. M. Riley. Microdialysis sampling for the investigation of dermal drug transport. Pharm. Res. 9:1256-1261 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 1256-1261
    • Ault, J.M.1    Lunte, C.E.2    Meltzer, N.M.3    Riley, C.M.4
  • 129
    • 0026652682 scopus 로고
    • In vivo sampling using loop microdialysis probes coupled to a liquid chromatograph
    • M. C. Linhares and P. T. Kissinger. In vivo sampling using loop microdialysis probes coupled to a liquid chromatograph. J. Chromatog. 578:157-163 (1992).
    • (1992) J. Chromatog. , vol.578 , pp. 157-163
    • Linhares, M.C.1    Kissinger, P.T.2
  • 130
    • 0028108473 scopus 로고
    • Simultaneous in vivo microdialysis in plasma and skeletal muscle: A study of the pharmacokinetic properties of levodopa by noncompartmental analysis
    • D. Deleu. S. Sarre, Y. Michotte, and G. Ebinger. Simultaneous in vivo microdialysis in plasma and skeletal muscle: a study of the pharmacokinetic properties of levodopa by noncompartmental analysis. J. Pharm. Sci. 83:25-28, (1994).
    • (1994) J. Pharm. Sci. , vol.83 , pp. 25-28
    • Deleu, D.1    Sarre, S.2    Michotte, Y.3    Ebinger, G.4
  • 131
    • 0029022372 scopus 로고
    • The effect of carbidopa and entacapone pretreatment on the L-dopa pharmacokinetics and metabolism in blood plasma and skeletal muscle in beagle dog: An in vivo microdialysis study
    • D. Deleu, S. Sarre, G. Ebinger, and Y. Michotte. The effect of carbidopa and entacapone pretreatment on the L-dopa pharmacokinetics and metabolism in blood plasma and skeletal muscle in beagle dog: an in vivo microdialysis study. J. Pharmacol. Exp Therap. 273:1323-1331, (1995).
    • (1995) J. Pharmacol. Exp Therap. , vol.273 , pp. 1323-1331
    • Deleu, D.1    Sarre, S.2    Ebinger, G.3    Michotte, Y.4
  • 133
    • 0024368823 scopus 로고
    • Pharmacokinetics of intravitreal injection. Assessment of a gentamicin model by ocular dialysis
    • J. Ben-Nun, D. A. Joyce, R. L. Cooper, S. J. Cringle, and I. J. Constable. Pharmacokinetics of intravitreal injection. Assessment of a gentamicin model by ocular dialysis. Invest. Ophthamol. Vis. Sci. 30:1055-1061 (1989).
    • (1989) Invest. Ophthamol. Vis. Sci. , vol.30 , pp. 1055-1061
    • Ben-Nun, J.1    Joyce, D.A.2    Cooper, R.L.3    Cringle, S.J.4    Constable, I.J.5
  • 134
    • 0026000989 scopus 로고
    • Intraocular microdialysis with permanently implanted probes in rabbit
    • J. Waga, A. Ohta, and B. Ehinger. Intraocular microdialysis with permanently implanted probes in rabbit. Acta Ophthalmologica. 69:618-624 (1991).
    • (1991) Acta Ophthalmologica , vol.69 , pp. 618-624
    • Waga, J.1    Ohta, A.2    Ehinger, B.3
  • 136
    • 0028114263 scopus 로고
    • Microdialysis measurement of catecholamines in rabbit vitreous after retinal laser photocoagulation
    • N. Stempels, M. J. Tassignon, S. Sarre, and J. Nguyen-Legros. Microdialysis measurement of catecholamines in rabbit vitreous after retinal laser photocoagulation. Experimental Eve Research. 59:433-439, (1994).
    • (1994) Experimental Eve Research , vol.59 , pp. 433-439
    • Stempels, N.1    Tassignon, M.J.2    Sarre, S.3    Nguyen-Legros, J.4
  • 138
    • 0029994811 scopus 로고    scopus 로고
    • Vitreous disposition of two acycloguanosine antivirals in the albino and pigmented rabbit models: A novel ocular microdialysis technique
    • P. M. Hughes, R. Krishnamoorthy, and A. K. Mitra. Vitreous disposition of two acycloguanosine antivirals in the albino and pigmented rabbit models: a novel ocular microdialysis technique. J. Ocular Pharmacol. Therap. 12:209-224 (1996).
    • (1996) J. Ocular Pharmacol. Therap. , vol.12 , pp. 209-224
    • Hughes, P.M.1    Krishnamoorthy, R.2    Mitra, A.K.3
  • 139
    • 0028939691 scopus 로고
    • Allopurinol: Kinetics, inhibition of xanthine oxidase activity, and protective effect in ischemic-reperfused canine heart as studied by cardiac microdialysis
    • A. I. Kuzmin, O. V. Tskitishvili, L. I. Serebryakova, V. I. Kapelko, I. V. Majorova, and O. S. Medvedev. Allopurinol: kinetics, inhibition of xanthine oxidase activity, and protective effect in ischemic-reperfused canine heart as studied by cardiac microdialysis. Journal of Cardiovascular Pharmacology 25:564-571 (1995).
    • (1995) Journal of Cardiovascular Pharmacology , vol.25 , pp. 564-571
    • Kuzmin, A.I.1    Tskitishvili, O.V.2    Serebryakova, L.I.3    Kapelko, V.I.4    Majorova, I.V.5    Medvedev, O.S.6
  • 140
    • 0025776340 scopus 로고
    • Measurements by microdialysis of free tissue concentrations of propranolol
    • P. Lonnroth, J. Carlsten, L. Johnson, and U. Smith. Measurements by microdialysis of free tissue concentrations of propranolol. J. Chromatog. 568:419-425 (1991).
    • (1991) J. Chromatog. , vol.568 , pp. 419-425
    • Lonnroth, P.1    Carlsten, J.2    Johnson, L.3    Smith, U.4
  • 141
    • 0027288104 scopus 로고
    • Pharmacokinetic measurement of drugs in lung epithelial lining fluid by microdialysis: Aminoglycoside antibiotics in rat bronchi
    • E. J. Eisenberg, P. Conzentino, W. M. Eickhoff, and K. C. Cundy. Pharmacokinetic measurement of drugs in lung epithelial lining fluid by microdialysis: aminoglycoside antibiotics in rat bronchi. J. Pharmacol Toxicolog. Methods 29:93-98 (1993).
    • (1993) J. Pharmacol Toxicolog. Methods , vol.29 , pp. 93-98
    • Eisenberg, E.J.1    Conzentino, P.2    Eickhoff, W.M.3    Cundy, K.C.4
  • 142
    • 0027412197 scopus 로고
    • In vivo microdialysis sampling in the bile, blood, and liver of rats to study the disposition of phenol
    • D. O. Scott, Lunte C. E. In vivo microdialysis sampling in the bile, blood, and liver of rats to study the disposition of phenol. Pharm. Res. 10:335-42, 1993.
    • (1993) Pharm. Res. , vol.10 , pp. 335-342
    • Scott, D.O.1    Lunte, C.E.2
  • 144
    • 0027289596 scopus 로고
    • Plasma microdialysis: A technique for continuous plasma sampling in freely moving rats
    • Z. Chen and R. W. Steger. Plasma microdialysis: A technique for continuous plasma sampling in freely moving rats. J Pharmacol. Toxicol. Meth. 29:111-118 (1993).
    • (1993) J Pharmacol. Toxicol. Meth. , vol.29 , pp. 111-118
    • Chen, Z.1    Steger, R.W.2
  • 145
    • 0029928807 scopus 로고    scopus 로고
    • Intravenous microdialysis in the mouse and the rat: Development and pharmacokinetic application of a new probe
    • P. A. Evrard, G. Deridder, and R. K. Verbeeck. Intravenous microdialysis in the mouse and the rat: Development and pharmacokinetic application of a new probe. Pharm. Res. 13:12-17 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 12-17
    • Evrard, P.A.1    Deridder, G.2    Verbeeck, R.K.3
  • 147
    • 0025314801 scopus 로고
    • In vivo microdialysis sampling coupled to liquid chromatography for the study of acetaminophen metabolism
    • D. O. Scott, L. R. Sorensen, and C. E. Lunte. In vivo microdialysis sampling coupled to liquid chromatography for the study of acetaminophen metabolism. J. Chromatog. 506:461-469 (1990).
    • (1990) J. Chromatog. , vol.506 , pp. 461-469
    • Scott, D.O.1    Sorensen, L.R.2    Lunte, C.E.3
  • 148
    • 0024957569 scopus 로고
    • Microdialysis-perfusion sampling for the investigation of phenol metabolism
    • Scott D. O., Bell M. A., and Lunte C. E. Microdialysis-perfusion sampling for the investigation of phenol metabolism. J. Pharmaceut. Biomed. Anal. 7:1249-1259 (1989).
    • (1989) J. Pharmaceut. Biomed. Anal. , vol.7 , pp. 1249-1259
    • Scott, D.O.1    Bell, M.A.2    Lunte, C.E.3
  • 149
    • 0026593487 scopus 로고
    • Potential use of microdialysis in pharmacokinetics: A protein binding study
    • M. Ekblom, M. Hammarlund-Udenaes, T. Lundqvist, and P. Sjoberg. Potential use of microdialysis in pharmacokinetics: A protein binding study. Pharm. Res. 9:155-158 (1992).
    • (1992) Pharm. Res. , vol.9 , pp. 155-158
    • Ekblom, M.1    Hammarlund-Udenaes, M.2    Lundqvist, T.3    Sjoberg, P.4
  • 150
  • 151
    • 0028309771 scopus 로고
    • Microdialysis: An alternative for in vitro and in vivo protein binding studies
    • A. L. Quellec, S. Dupin, A. E. Tufenkj, P. Genissel, and G. Houin. Microdialysis: An alternative for in vitro and in vivo protein binding studies. Pharm. Res. 11:835-838 (1994).
    • (1994) Pharm. Res. , vol.11 , pp. 835-838
    • Quellec, A.L.1    Dupin, S.2    Tufenkj, A.E.3    Genissel, P.4    Houin, G.5
  • 152
    • 0029996133 scopus 로고    scopus 로고
    • The binding of cyclosporin a to human plasma: An in vitro microdialysis study
    • H. Yang and W. F. Elmquist. The binding of cyclosporin A to human plasma: An in vitro microdialysis study. Pharm. Res. 13:620-625 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 620-625
    • Yang, H.1    Elmquist, W.F.2
  • 153
    • 8244227649 scopus 로고
    • Amphotericin B plasma protein-binding studies using in vitro microdialysis and on-line HPLC
    • Q. Wang, and W. F. Elmquist. Amphotericin B plasma protein-binding studies using in vitro microdialysis and on-line HPLC. Pharm. Res. 10:S-394 (1994).
    • (1994) Pharm. Res. , vol.10
    • Wang, Q.1    Elmquist, W.F.2
  • 154
    • 0028575992 scopus 로고
    • In vivo microdialysis for pharmacokinetic investigations: A plasma protein binding study of valproate in rabbits
    • M. Nakashima, N. Takeuchi, M. Hamada, K. Matsuyama, M. Ichikawa, and S. Goto. In vivo microdialysis for pharmacokinetic investigations: a plasma protein binding study of valproate in rabbits. Biol. Pharm. Bull. 17:1630-1634 (1994).
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 1630-1634
    • Nakashima, M.1    Takeuchi, N.2    Hamada, M.3    Matsuyama, K.4    Ichikawa, M.5    Goto, S.6
  • 155
    • 0029978436 scopus 로고    scopus 로고
    • Concentration-dependent plasma protein binding of flubiprofen in the rat: An in vivo microdialysis study
    • P. A. Evrard, J. Cumps, and R. K. Verbeeck. Concentration-dependent plasma protein binding of flubiprofen in the rat: An in vivo microdialysis study. Pharm. Res. 13:18-22 (1996).
    • (1996) Pharm. Res. , vol.13 , pp. 18-22
    • Evrard, P.A.1    Cumps, J.2    Verbeeck, R.K.3
  • 156
    • 0024464154 scopus 로고
    • Plasma binding and tranpsort of diazepam across the blood-brain barrier
    • R. K. Dubey, C. V. McAllister, M. Inoue, and G. R. Wilkinson. Plasma binding and tranpsort of diazepam across the blood-brain barrier. J. Clin. Invest. 84:1 155-1159 (1989).
    • (1989) J. Clin. Invest. , vol.84 , pp. 1155-1159
    • Dubey, R.K.1    McAllister, C.V.2    Inoue, M.3    Wilkinson, G.R.4
  • 157
    • 0026577307 scopus 로고
    • Intravenous microdialysis sampling in awake, freely-moving rats
    • M.Telting-Diaz, D. O. Scott, and C. E. Lunte. Intravenous microdialysis sampling in awake, freely-moving rats. Anal. Chem. 64:806-810 (1992).
    • (1992) Anal. Chem. , vol.64 , pp. 806-810
    • Telting-Diaz, M.1    Scott, D.O.2    Lunte, C.E.3
  • 158
    • 8244238728 scopus 로고
    • Drug binding to blood cells
    • M. M. Reidenberg and S. Erill (eds.), Praeger Pub., New York
    • M. Ehrnebo. Drug binding to blood cells. In M. M. Reidenberg and S. Erill (eds.), Drug-protein binding, Praeger Pub., New York, 1986, pp. 128-137.
    • (1986) Drug-protein Binding , pp. 128-137
    • Ehrnebo, M.1
  • 161
  • 164
    • 0025214042 scopus 로고
    • In vivo subcutaneous glucose kinetics after glucose ingestion in obesity and fasting. Scand
    • E. Hagstrom, P. Arner, P. Engfeldt, S. Rossner, and J. Bolinder. In vivo subcutaneous glucose kinetics after glucose ingestion in obesity and fasting. Scand. J. Clin. Lab. Invest. 50:129-136 (1990).
    • (1990) J. Clin. Lab. Invest. , vol.50 , pp. 129-136
    • Hagstrom, E.1    Arner, P.2    Engfeldt, P.3    Rossner, S.4    Bolinder, J.5
  • 165
    • 0028038749 scopus 로고
    • Adipose tissue metabolism in humans determined by vein catheterization and microdialysis techniques
    • L. Simonsen, J. Bulow, and J. Madsen. Adipose tissue metabolism in humans determined by vein catheterization and microdialysis techniques. Am. J. Physiol. 266:E357-65 (1994).
    • (1994) Am. J. Physiol. , vol.266
    • Simonsen, L.1    Bulow, J.2    Madsen, J.3
  • 166
    • 0028266141 scopus 로고
    • Influence of operation on glucose metabolism and lipolysis in human adipose tissue: A microdialysis study
    • G. Fellander, J. Nordenstrom, U. Ungerstedt, P. Arner, and J. Bolinder. Influence of operation on glucose metabolism and lipolysis in human adipose tissue: a microdialysis study. Eur. J. Surg. 160:87-95 (1994).
    • (1994) Eur. J. Surg. , vol.160 , pp. 87-95
    • Fellander, G.1    Nordenstrom, J.2    Ungerstedt, U.3    Arner, P.4    Bolinder, J.5
  • 167
    • 0027184803 scopus 로고
    • Assessment of adipose tissue metabolism in man: Comparison of Fick and microdialysis techniques
    • P. Arner and J. Bulow. Assessment of adipose tissue metabolism in man: comparison of Fick and microdialysis techniques. Clin. Science 85:247-56 (1993).
    • (1993) Clin. Science , vol.85 , pp. 247-256
    • Arner, P.1    Bulow, J.2
  • 168
    • 0027313517 scopus 로고
    • Measurement by microdialysis of the insulin concentration in subcutaneous interstitial fluid. Importance of the endothelial barrier for insulin
    • P. A. Jansson, J. P. Fowelin, H. P. von Schenck, U. P. Smith, and P. N. Lonnroth. Measurement by microdialysis of the insulin concentration in subcutaneous interstitial fluid. Importance of the endothelial barrier for insulin. Diabetes 42:1469-73 (1993).
    • (1993) Diabetes , vol.42 , pp. 1469-1473
    • Jansson, P.A.1    Fowelin, J.P.2    Von Schenck, H.P.3    Smith, U.P.4    Lonnroth, P.N.5
  • 169
    • 0026041915 scopus 로고
    • Drug distribution studies with microdialysis. III: Extracellular concentration of caffeine in adipose tissue in man
    • L. Stahle, P. Arner, and U. Ungerstedt. Drug distribution studies with microdialysis. III: Extracellular concentration of caffeine in adipose tissue in man. Life Sci. 49:1853-8 (1991).
    • (1991) Life Sci. , vol.49 , pp. 1853-1858
    • Stahle, L.1    Arner, P.2    Ungerstedt, U.3
  • 172
    • 0025083203 scopus 로고
    • Glucocorticoids suppress levels of immunoreactive bradykinin in inflamed tissue as evaluated by microdialysis probes
    • K. M. Hargreaves and A. Costello. Glucocorticoids suppress levels of immunoreactive bradykinin in inflamed tissue as evaluated by microdialysis probes. Clin. Pharmacol. Ther. 48:168-178: (1990).
    • (1990) Clin. Pharmacol. Ther. , vol.48 , pp. 168-178
    • Hargreaves, K.M.1    Costello, A.2
  • 173
    • 0027216769 scopus 로고
    • Urea kinetics during hemodialysis measured by microdialysis - A novel technique
    • G. S. Metry, P. O. Attman, P. Lonnroth, S. N. Beshara, and M. Aurell. Urea kinetics during hemodialysis measured by microdialysis - a novel technique. Kidney International 44:622-629 (1993).
    • (1993) Kidney International , vol.44 , pp. 622-629
    • Metry, G.S.1    Attman, P.O.2    Lonnroth, P.3    Beshara, S.N.4    Aurell, M.5
  • 174
    • 0029074055 scopus 로고
    • Microdialysis in cutaneous pharmacology: Kinetic analysis of transdermally delivered nicotine
    • L. Hegemann, C. Forstinger, B. Partsch, I. Lagler, S. Krotz, and K. Wolff. Microdialysis in cutaneous pharmacology: kinetic analysis of transdermally delivered nicotine. J. Invest. Derm. 104:839-843 (1995).
    • (1995) J. Invest. Derm. , vol.104 , pp. 839-843
    • Hegemann, L.1    Forstinger, C.2    Partsch, B.3    Lagler, I.4    Krotz, S.5    Wolff, K.6
  • 175
    • 0025865965 scopus 로고
    • Ethanol absorption across human skin measured by in vivo microdialysis technique
    • C. Anderson, T. Andersson, and M. Molander. Ethanol absorption across human skin measured by in vivo microdialysis technique. Acta Dermato-Venereologica 71:389-393 (1991).
    • (1991) Acta Dermato-Venereologica , vol.71 , pp. 389-393
    • Anderson, C.1    Andersson, T.2    Molander, M.3
  • 176
    • 0028314849 scopus 로고
    • Changes in skin circulation after insertion of a microdialysis probe visualized by laser Doppler perfusion imagine
    • C. Anderson, T. Andersson, and K. Wardell. Changes in skin circulation after insertion of a microdialysis probe visualized by laser Doppler perfusion imagine. J. Invest. Derm. 102:807-811 (1994).
    • (1994) J. Invest. Derm. , vol.102 , pp. 807-811
    • Anderson, C.1    Andersson, T.2    Wardell, K.3
  • 177
    • 0027757119 scopus 로고
    • Microdialysis probe for transcutaneous monitoring of ethanol and glucose in humans
    • J. de Boer, H. Plijter-Groendijk, and J. Korf. Microdialysis probe for transcutaneous monitoring of ethanol and glucose in humans. J. Appl. Physiol. 75:2825-2830 (1993).
    • (1993) J. Appl. Physiol. , vol.75 , pp. 2825-2830
    • De Boer, J.1    Plijter-Groendijk, H.2    Korf, J.3
  • 178
    • 0027379244 scopus 로고
    • Chemical monitoring of intensive care patients using intravenous microdialysis
    • H. Stjernstrom, T. Karlsson, U. Ungerstedt, and L. Hillered. Chemical monitoring of intensive care patients using intravenous microdialysis. Intensive Care Med. 19:423-428 (1993).
    • (1993) Intensive Care Med. , vol.19 , pp. 423-428
    • Stjernstrom, H.1    Karlsson, T.2    Ungerstedt, U.3    Hillered, L.4
  • 179
    • 0028968680 scopus 로고
    • Intracerebral microdialysis. In vivo study of an acute focal ischemic model of the human brain
    • R. Kanthan, A. Shuaib, R. Griebel, and H Miyashita. Intracerebral microdialysis. In vivo study of an acute focal ischemic model of the human brain. Stroke 26:870-873 (1995).
    • (1995) Stroke , vol.26 , pp. 870-873
    • Kanthan, R.1    Shuaib, A.2    Griebel, R.3    Miyashita, H.4
  • 180
    • 85013507754 scopus 로고
    • In vivo neurochemistry of the conscious human brain: Intrahippocampal microdialysis in epilepsy
    • T. E. Robinson and J. B. Justice, Jr. (Eds.). Elsevier. Amsterdam
    • M. J. During. In vivo neurochemistry of the conscious human brain: intrahippocampal microdialysis in epilepsy. In: T. E. Robinson and J. B. Justice, Jr. (Eds.). Microdialysis in the Neurosciences. Techniques in the Behavioral and Neural Sciences. Vol. 7, Elsevier. Amsterdam, pp. 425-442 (1991).
    • (1991) Microdialysis in the Neurosciences. Techniques in the Behavioral and Neural Sciences , vol.7 , pp. 425-442
    • During, M.J.1
  • 181
    • 0026318344 scopus 로고
    • The in vivo microdialysis recovery of dopamine is altered independently of basal level by 6-hydroxydopamine lesions to the nucleus accumbens
    • L. H. Parsons, A. D. Smith, and J. B. Justice. Jr. The in vivo microdialysis recovery of dopamine is altered independently of basal level by 6-hydroxydopamine lesions to the nucleus accumbens. J. Neurosci. Methods 40:139-147 (1991).
    • (1991) J. Neurosci. Methods , vol.40 , pp. 139-147
    • Parsons, L.H.1    Smith, A.D.2    Justice Jr., J.B.3
  • 182
    • 0026566537 scopus 로고
    • In vivo calibration of microdialysis probes for exogenous compounds
    • S. Menacherry, W. Hubert, and J. B. Justice Jr. In vivo calibration of microdialysis probes for exogenous compounds. Anal. Chem. 64:577-583 (1992).
    • (1992) Anal. Chem. , vol.64 , pp. 577-583
    • Menacherry, S.1    Hubert, W.2    Justice Jr., J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.