-
1
-
-
0028299479
-
Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system
-
ADKISON, K. D. K., ARTKU, A. A., POWERS, K. M. AND SHEN, D. D.: Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system. J. Pharmacol. Exp. Ther. 268: 797-805, 1994.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 797-805
-
-
Adkison, K.D.K.1
Artku, A.A.2
Powers, K.M.3
Shen, D.D.4
-
2
-
-
0025114459
-
Central nervous system toxicity of quinolones: Human and animal findings
-
CHRIST, W.: Central nervous system toxicity of quinolones: Human and animal findings. J. Antimicrob. Chemother. 26: suppl. B, 219-225, 1990.
-
(1990)
J. Antimicrob. Chemother.
, vol.26
, Issue.SUPPL. B
, pp. 219-225
-
-
Christ, W.1
-
3
-
-
0021807216
-
Blood-brain barrier transport of valproic acid
-
CORNFORD, E. M., DIEP, C. P., PAHDRIDGE, W. M.: Blood-brain barrier transport of valproic acid. J. Neurochem. 44:1541-1550, 1985.
-
(1985)
J. Neurochem.
, vol.44
, pp. 1541-1550
-
-
Cornford, E.M.1
Diep, C.P.2
Pahdridge, W.M.3
-
4
-
-
0027768971
-
Microdialysis study of zidovudine (AZT) transport in rat brain
-
DYKSTRA, K. H., ARYA, A., AHRIOLA, D. M., BUNGAY, P. M., MORRISON, P. F. AND DEDRICK, R. L.: Microdialysis study of zidovudine (AZT) transport in rat brain. J. Pharmacol. Exp. Ther. 267: 1227-1236, 1993.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 1227-1236
-
-
Dykstra, K.H.1
Arya, A.2
Ahriola, D.M.3
Bungay, P.M.4
Morrison, P.F.5
Dedrick, R.L.6
-
5
-
-
0026437666
-
Transport of pefloxacin across the bacterial cytoplasmic membrane in quinolone-susceptible Staphylococcus aureus
-
FURET, Y. X., DESHUSSES, J. AND PECHÈRE, J. C.: Transport of pefloxacin across the bacterial cytoplasmic membrane in quinolone-susceptible Staphylococcus aureus. Antimicrob. Agents Chemother. 36: 2506-2511, 1992.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 2506-2511
-
-
Furet, Y.X.1
Deshusses, J.2
Pechère, J.C.3
-
6
-
-
0021160207
-
Pharmacokinetic studies of norfloxacin in laboratory animals
-
GILFILLAN, E. C., PELAK, B. A., BLAND, J. A., MALATESTA, P. F. AND GADEBUSCH, H. H.: Pharmacokinetic studies of norfloxacin in laboratory animals. Chemotherapy 30: 288-296, 1984.
-
(1984)
Chemotherapy
, vol.30
, pp. 288-296
-
-
Gilfillan, E.C.1
Pelak, B.A.2
Bland, J.A.3
Malatesta, P.F.4
Gadebusch, H.H.5
-
7
-
-
0027729568
-
Blood-brain barrier transport rate of quinolone antibacterials evaluated in cerebrovascular endothelial cell cultures
-
JAEHDE, U., GOTO, T., DE BOER, A. G. AND BREIMER, D. D.: Blood-brain barrier transport rate of quinolone antibacterials evaluated in cerebrovascular endothelial cell cultures. Eur. J. Phar. Sci. 1: 49-55, 1993.
-
(1993)
Eur. J. Phar. Sci.
, vol.1
, pp. 49-55
-
-
Jaehde, U.1
Goto, T.2
De Boer, A.G.3
Breimer, D.D.4
-
8
-
-
0026978845
-
Cerebrospinal fluid transport and disposition of the quinolones ciprofloxacin and pefloxacin in rats
-
JAEHDE, U., LANGEMEIJER, M. W. E., DE BOER, A. G. AND BREIMER, D. D.: Cerebrospinal fluid transport and disposition of the quinolones ciprofloxacin and pefloxacin in rats. J. Pharmacol. Exp. Ther. 263: 1140-1146, 1992.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 1140-1146
-
-
Jaehde, U.1
Langemeijer, M.W.E.2
De Boer, A.G.3
Breimer, D.D.4
-
9
-
-
0022480849
-
Pharmacokinetics of a new quinolone, AM-833, in mice, rats, rabbits, dogs, and monkeys
-
KUSAJIMA, H., ISHIKAWA, N., MACHIDA, M., UCHIDA, H. AND IRIKURA, T.: Pharmacokinetics of a new quinolone, AM-833, in mice, rats, rabbits, dogs, and monkeys. Antimicrob. Agents Chemother. 30: 304-309, 1986.
-
(1986)
Antimicrob. Agents Chemother.
, vol.30
, pp. 304-309
-
-
Kusajima, H.1
Ishikawa, N.2
Machida, M.3
Uchida, H.4
Irikura, T.5
-
10
-
-
0019124032
-
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
-
LEVIN, V. A.: Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med. Chem. 23: 682-684, 1980.
-
(1980)
J. Med. Chem.
, vol.23
, pp. 682-684
-
-
Levin, V.A.1
-
11
-
-
0026341402
-
Facilitated transport of cefodizime into the rat central nervous system
-
MATSUSHITA, H., SUZUKI, H., SUGIYAMA, Y., SAWADA, Y., IGA, T., KAWAGUCHI, Y. AND HANANO, M.: Facilitated transport of cefodizime into the rat central nervous system. J. Pharmacol. Exp. Ther. 259: 620-625, 1991.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 620-625
-
-
Matsushita, H.1
Suzuki, H.2
Sugiyama, Y.3
Sawada, Y.4
Iga, T.5
Kawaguchi, Y.6
Hanano, M.7
-
12
-
-
0021223885
-
Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans
-
MONTAY, G., GOUEFFON, Y. AND ROQUET, F.: Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans. Antimicrob. Agents Chemother. 25: 463-472, 1984.
-
(1984)
Antimicrob. Agents Chemother.
, vol.25
, pp. 463-472
-
-
Montay, G.1
Goueffon, Y.2
Roquet, F.3
-
13
-
-
0023957287
-
Clinical pharmacokinetics of the newer antibacterial 4-quinolones
-
NEUMAN, M.: Clinical pharmacokinetics of the newer antibacterial 4-quinolones. Clin. Pharmacokinet. 14: 96-121, 1988.
-
(1988)
Clin. Pharmacokinet.
, vol.14
, pp. 96-121
-
-
Neuman, M.1
-
14
-
-
0024409224
-
Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus
-
NOHJOH, T., SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus. J. Pharmacol. Exp. Ther. 250: 324-328, 1989.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.250
, pp. 324-328
-
-
Nohjoh, T.1
Suzuki, H.2
Sawada, Y.3
Sugiyama, Y.4
Iga, T.5
Hanano, M.6
-
15
-
-
0021824941
-
Cerebrospinal fluid uptake and peripheral distribution of centrally acting drugs: Relation to lipid solubility
-
OCHS, H. R., GREENBLATT, D. J., ABERNETHY, D. R., ARENDT, R. M., GERLOFF, J., EICHELKRAUT, W. AND HAHN, N.: Cerebrospinal fluid uptake and peripheral distribution of centrally acting drugs: Relation to lipid solubility. J. Pharm. Pharmacol. 37: 428-431, 1985.
-
(1985)
J. Pharm. Pharmacol.
, vol.37
, pp. 428-431
-
-
Ochs, H.R.1
Greenblatt, D.J.2
Abernethy, D.R.3
Arendt, R.M.4
Gerloff, J.5
Eichelkraut, W.6
Hahn, N.7
-
16
-
-
0028010511
-
Kinetics of active efflux via choroid plexus of β-lactam antibiotics from the CSF into the circulation
-
OGAWA, M., SUZUKI, H., SAWADA, Y., HANANO, M. AND SUGIYAMA, Y.: Kinetics of active efflux via choroid plexus of β-lactam antibiotics from the CSF into the circulation. Am. J. Physiol. 266: R392-R399, 1994.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Ogawa, M.1
Suzuki, H.2
Sawada, Y.3
Hanano, M.4
Sugiyama, Y.5
-
17
-
-
0026554353
-
Species-related stereoselective disposition of ofloxacin in the rat, dog and monkey
-
OKAZAKI, O., KURATA, T., HAKUSUI, H. AND TACHIZAWA, H.: Species-related stereoselective disposition of ofloxacin in the rat, dog and monkey. Xenobiotica 22: 439-450, 1992.
-
(1992)
Xenobiotica
, vol.22
, pp. 439-450
-
-
Okazaki, O.1
Kurata, T.2
Hakusui, H.3
Tachizawa, H.4
-
18
-
-
0029922224
-
Characterization of the transport properties of a quinolone antibiotic, fleroxacin, in rat choroic plexus
-
OOIE, T., SUZUKI, H., TERASAKI, T. AND SUGIYAMA, Y.: Characterization of the transport properties of a quinolone antibiotic, fleroxacin, in rat choroic plexus. Pharm. Res. 13: 512-516, 1996.
-
(1996)
Pharm. Res.
, vol.13
, pp. 512-516
-
-
Ooie, T.1
Suzuki, H.2
Terasaki, T.3
Sugiyama, Y.4
-
19
-
-
0029764186
-
Kinetics of quinolone antibiotics in rats: Efflux from cerebrospinal fluid to the circulation
-
in prees
-
OOIE, T., SUZUKI, H., TERASAKI, T. AND SUGIYAMA, Y.: Kinetics of quinolone antibiotics in rats: Efflux from cerebrospinal fluid to the circulation. Pharm Res. in prees.
-
Pharm Res.
-
-
Ooie, T.1
Suzuki, H.2
Terasaki, T.3
Sugiyama, Y.4
-
20
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
SCHINKEL, A. H., SMIT, J. J. M., TELLINGEN, O., BEIJNEN, J. H., WAGENAAR, E. DEEMTER, L., MOL, C. A. A. M., VALK, M. A., ROBANUS-MAANDAG, E. C., RIELE H. P. J., BERNS, A. J. M. AND BORST, P.: Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77: 491-502, 1994.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Deemter, L.6
Mol, C.A.A.M.7
Valk, M.A.8
Robanus-Maandag, E.C.9
Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
21
-
-
0024516261
-
Pharmacokinetic disposition of quinolones in human body fluids and tissues
-
SÖRGEL, F., JAEHDE, U., NABER, K. AND STEPHAN, U.: Pharmacokinetic disposition of quinolones in human body fluids and tissues. Clin. Pharmacokinet. 16: suppl. 1, 5-24, 1989.
-
(1989)
Clin. Pharmacokinet.
, vol.16
, Issue.1 SUPPL.
, pp. 5-24
-
-
Sörgel, F.1
Jaehde, U.2
Naber, K.3
Stephan, U.4
-
22
-
-
0022630276
-
Ceftriaxone pharmacokinetics in the central nervous system
-
SPECTOR, R.: Ceftriaxone pharmacokinetics in the central nervous system. J Pharmacol. Exp. Ther. 236: 380-383, 1986.
-
(1986)
J Pharmacol. Exp. Ther.
, vol.236
, pp. 380-383
-
-
Spector, R.1
-
23
-
-
0022908520
-
Traneport of cimetidine by the rat choroid plexus in vitro
-
SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Traneport of cimetidine by the rat choroid plexus in vitro. J. Pharmacol. Exp. Ther. 239: 927-935, 1986.
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.239
, pp. 927-935
-
-
Suzuki, H.1
Sawada, Y.2
Sugiyama, Y.3
Iga, T.4
Hanano, M.5
-
24
-
-
0023615581
-
Transport of benzylpenicillin by the rat choroid plexus in vitro
-
SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T. AND HANANO, M.: Transport of benzylpenicillin by the rat choroid plexus in vitro. J. Pharmacol. Exp. Ther. 242: 660-665, 1987.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 660-665
-
-
Suzuki, H.1
Sawada, Y.2
Sugiyama, Y.3
Iga, T.4
Hanano, M.5
-
25
-
-
0024441103
-
Transport of imipenem, a novel carbapenem antibiotic, in the rat central nervous system
-
SUZUKI, H., SAWADA, Y., SUGIYAMA, Y., IGA, T., HANANO, M. AND SPECTOR, R.: Transport of imipenem, a novel carbapenem antibiotic, in the rat central nervous system. J. Pharmacol. Exp. Ther. 250: 979-984, 1989.
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.250
, pp. 979-984
-
-
Suzuki, H.1
Sawada, Y.2
Sugiyama, Y.3
Iga, T.4
Hanano, M.5
Spector, R.6
-
26
-
-
0025353198
-
Possibility for induction of convulsion by fleroxacin and its disposition in the central nervous system in animals
-
TAGA, F., KOBAYASHI, F., SAITO, S., OOIE, T., KAWAHARA, F., UCHIDA, H., SHIMADA, J., HORI, S. AND SAKAI, O.: Possibility for induction of convulsion by fleroxacin and its disposition in the central nervous system in animals. Arzneim.-Forsch./Drug Res. 40: 900-904, 1990.
-
(1990)
Arzneim.-Forsch./Drug Res.
, vol.40
, pp. 900-904
-
-
Taga, F.1
Kobayashi, F.2
Saito, S.3
Ooie, T.4
Kawahara, F.5
Uchida, H.6
Shimada, J.7
Hori, S.8
Sakai, O.9
-
27
-
-
0026669192
-
Functional involvement of P-glycoprotein in blood-brain barrier
-
TATSUTA, T., NAITO, M., OH-HARA, T., SUGAWARA, I. AND TSURUO, T.: Functional involvement of P-glycoprotein in blood-brain barrier. J. Biol. Chem. 267: 20383-20391, 1992.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20383-20391
-
-
Tatsuta, T.1
Naito, M.2
Oh-Hara, T.3
Sugawara, I.4
Tsuruo, T.5
-
28
-
-
0026760889
-
P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells
-
TSUJI, A., TERASAKI, T., TAKABATAKE, Y., TENDA, Y., TAMAI, I., YAMASHIMA, T., MORITANI, S., TSURUO, T. AND YAMASHITA, J.: P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells. Life Sci. 51:1427-1437, 1992.
-
(1992)
Life Sci.
, vol.51
, pp. 1427-1437
-
-
Tsuji, A.1
Terasaki, T.2
Takabatake, Y.3
Tenda, Y.4
Tamai, I.5
Yamashima, T.6
Moritani, S.7
Tsuruo, T.8
Yamashita, J.9
-
29
-
-
0003961244
-
-
American Society for Microbiology, Washington, DC
-
WOLFSON, J. S. AND HOOPER, D. C.: Quinolone Antimicrobial Agents, American Society for Microbiology, Washington, DC, 1989.
-
(1989)
Quinolone Antimicrobial Agents
-
-
Wolfson, J.S.1
Hooper, D.C.2
-
30
-
-
0019854279
-
A pharmacokinetic analysis program (MULTI) for microcomputer
-
YAMAOKA, K., TANIGAWARA, Y., NAKAGAWA, T. AND UNO, T.: A pharmacokinetic analysis program (MULTI) for microcomputer. J. Pharmacobio-Dyn. 4: 879-885, 1981.
-
(1981)
J. Pharmacobio-Dyn.
, vol.4
, pp. 879-885
-
-
Yamaoka, K.1
Tanigawara, Y.2
Nakagawa, T.3
Uno, T.4
|