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Volumn 36, Issue 2-3, 1999, Pages 165-178

In vitro model for evaluating drug transport across the blood-brain barrier

Author keywords

Astrocyte; Brain capillary endothelial cell; Coculture; Drug delivery; P glycoprotein

Indexed keywords

BLOOD; BRAIN; CELLS; NEUROPHYSIOLOGY; PHYSIOLOGICAL MODELS; PROTEINS;

EID: 0033526177     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(98)00083-0     Document Type: Review
Times cited : (325)

References (24)
  • 1
    • 0023022986 scopus 로고
    • Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism
    • Audus K.L., Borchardt R.T. Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism. Pharmaceutical Res. 3:1986;81-87.
    • (1986) Pharmaceutical Res. , vol.3 , pp. 81-87
    • Audus, K.L.1    Borchardt, R.T.2
  • 2
    • 0025329190 scopus 로고
    • Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier
    • Pardridge W.M., Triguero D., Yang J., Cancilla P.A. Comparison of in vitro and in vivo models of drug transcytosis through the blood-brain barrier. J. Pharmacol. Exp. Ther. 253:1990;884-891.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 884-891
    • Pardridge, W.M.1    Triguero, D.2    Yang, J.3    Cancilla, P.A.4
  • 3
    • 0025218499 scopus 로고
    • Development of the blood-brain barrier
    • Risau W., Wolburg H. Development of the blood-brain barrier. TINS. 13:1990;174-178.
    • (1990) TINS , vol.13 , pp. 174-178
    • Risau, W.1    Wolburg, H.2
  • 5
    • 0025837039 scopus 로고
    • Immortalization of brain capillary endothelial cells with maintenance of structural characteristics of the blood-brain barrier endothelium in vitro
    • Durieu-Trautmann O., Foignant-Chaverot N., Perdomo J., Gounon A., Strosberg A.D., Couraud P.O. Immortalization of brain capillary endothelial cells with maintenance of structural characteristics of the blood-brain barrier endothelium in vitro. Cell. Dev. Biol. 27A:1991;771-778.
    • (1991) Cell. Dev. Biol. , vol.27 , pp. 771-778
    • Durieu-Trautmann, O.1    Foignant-Chaverot, N.2    Perdomo, J.3    Gounon, A.4    Strosberg, A.D.5    Couraud, P.O.6
  • 6
  • 7
    • 0030726926 scopus 로고    scopus 로고
    • Development of immortalized human cerebrovascular endothelium cell line as an in vitro model of the human blood-brain barrier
    • Muruganandam A., Moorhouse H., Monette R., Durkin J.P., Stanimirovic D.B. Development of immortalized human cerebrovascular endothelium cell line as an in vitro model of the human blood-brain barrier. FASEB J. 11:1997;1187-1197.
    • (1997) FASEB J. , vol.11 , pp. 1187-1197
    • Muruganandam, A.1    Moorhouse, H.2    Monette, R.3    Durkin, J.P.4    Stanimirovic, D.B.5
  • 8
    • 0029759938 scopus 로고    scopus 로고
    • A dynamic model of the blood-brain barrier 'in vitro'
    • Stanness K.A., Guatteo E., Janigro D. A dynamic model of the blood-brain barrier 'in vitro'. NeuroToxicology. 17(2):1996;481-496.
    • (1996) NeuroToxicology , vol.17 , Issue.2 , pp. 481-496
    • Stanness, K.A.1    Guatteo, E.2    Janigro, D.3
  • 10
    • 0025265046 scopus 로고
    • An easier, reproductible and mass production method to study the blood-brain barrier 'in vitro' and in vivo' models
    • Dehouck M.P., Méresse S., Delorme P., Fruchart J.C., Cecchelli R. An easier, reproductible and mass production method to study the blood-brain barrier 'in vitro' and in vivo' models. J. Neurochem. 54:1990;1790-1797.
    • (1990) J. Neurochem. , vol.54 , pp. 1790-1797
    • Dehouck, M.P.1    Méresse, S.2    Delorme, P.3    Fruchart, J.C.4    Cecchelli, R.5
  • 12
    • 0028803733 scopus 로고
    • Drug transport to the brain: Comparison between in vitro and in vivo models of the blood-brain barrier
    • Dehouck M.P., Dehouck B., Schluep C., Lemaire M., Cecchelli R. Drug transport to the brain: comparison between in vitro and in vivo models of the blood-brain barrier. Eur. J. Pharmaceut. Sci. 3:1995;357-365.
    • (1995) Eur. J. Pharmaceut. Sci. , vol.3 , pp. 357-365
    • Dehouck, M.P.1    Dehouck, B.2    Schluep, C.3    Lemaire, M.4    Cecchelli, R.5
  • 13
    • 0344457207 scopus 로고    scopus 로고
    • Perspectives
    • in: A.G. de Boer, W. Sutanto (Eds.), Harwood Academic Publishers
    • A.G. DeBoer, W. Sutanto, Perspectives, in: A.G. de Boer, W. Sutanto (Eds.), Drug Transport Across the Blood-brain Barrier, Harwood Academic Publishers, 1997, pp. 215-216.
    • (1997) Drug Transport Across the Blood-brain Barrier , pp. 215-216
    • DeBoer, A.G.1    Sutanto, W.2
  • 14
    • 0344889004 scopus 로고    scopus 로고
    • A co-culture of brain capillary endothelial cells and astrocytes: An in vitro blood-brain barrier for studying drug transport to the brain
    • in: A.G. de Boer, W. Sutanto (Eds.), Harwood Academic Publishers
    • B. Dehouck, R. Cecchelli, M.P. Dehouck, A co-culture of brain capillary endothelial cells and astrocytes: An in vitro blood-brain barrier for studying drug transport to the brain, in: A.G. de Boer, W. Sutanto (Eds.), Drug Transport Across the Blood-brain Barrier, Harwood Academic Publishers, 1997, pp. 69-79.
    • (1997) Drug Transport Across the Blood-brain Barrier , pp. 69-79
    • Dehouck, B.1    Cecchelli, R.2    Dehouck, M.P.3
  • 15
    • 0028342454 scopus 로고
    • Upregulation of the low density lipoprotein receptor at the blood-brain barrier: Intercommunications between brain capillary endothelial cells and astrocytes
    • Dehouck B., Dehouck M.P., Fruchart J.C., Cecchelli R. Upregulation of the low density lipoprotein receptor at the blood-brain barrier: Intercommunications between brain capillary endothelial cells and astrocytes. J. Cell. Biol. 126:1994;465-473.
    • (1994) J. Cell. Biol. , vol.126 , pp. 465-473
    • Dehouck, B.1    Dehouck, M.P.2    Fruchart, J.C.3    Cecchelli, R.4
  • 16
    • 0030755944 scopus 로고    scopus 로고
    • A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier
    • Dehouck B., Fenart L., Dehouck M.P., Pierce A., Torpier G., Cecchelli R. A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier. J. Cell. Biol. 138:1997;877-888.
    • (1997) J. Cell. Biol. , vol.138 , pp. 877-888
    • Dehouck, B.1    Fenart, L.2    Dehouck, M.P.3    Pierce, A.4    Torpier, G.5    Cecchelli, R.6
  • 17
    • 0029867619 scopus 로고    scopus 로고
    • Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells
    • Descamps L., Dehouck M.P., Torpier G., Cecchelli R. Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells. Am. J. Physiol. 270:1996;H1150-H1158.
    • (1996) Am. J. Physiol. , vol.270
    • Descamps, L.1    Dehouck, M.P.2    Torpier, G.3    Cecchelli, R.4
  • 18
    • 0031819596 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein: Rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier
    • Fenart L., Buée-Scherrer V., Descamps L., Duhem C., Poullain M.G., Cecchelli R., Dehouck M.P. Inhibition of P-glycoprotein: Rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier. Pharm. Res. 15(7):1998;993-1000.
    • (1998) Pharm. Res. , vol.15 , Issue.7 , pp. 993-1000
    • Fenart, L.1    Buée-Scherrer, V.2    Descamps, L.3    Duhem, C.4    Poullain, M.G.5    Cecchelli, R.6    Dehouck, M.P.7
  • 19
    • 0028043571 scopus 로고
    • Enhanced expression by the brain matrix of P-glycoprotein in brain capillary endothelial cells
    • Tatsuta T., Naito M., Mikami K., Tsuoro T. Enhanced expression by the brain matrix of P-glycoprotein in brain capillary endothelial cells. Cell growth and Differentiation. 5:1994;1145-1152.
    • (1994) Cell Growth and Differentiation , vol.5 , pp. 1145-1152
    • Tatsuta, T.1    Naito, M.2    Mikami, K.3    Tsuoro, T.4
  • 21
    • 0025295847 scopus 로고
    • Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins
    • Triguero D., Buciak J., Pardridge W.M. Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins. J. Neurochem. 54:1990;1882-1888.
    • (1990) J. Neurochem. , vol.54 , pp. 1882-1888
    • Triguero, D.1    Buciak, J.2    Pardridge, W.M.3
  • 22
    • 0018849619 scopus 로고
    • γ-Glutamyltranspeptidase in isolated brain endothelial cells: Induction by glial cells in vitro
    • DeBault L.E., Cancilla P.A. γ-Glutamyltranspeptidase in isolated brain endothelial cells: induction by glial cells in vitro. Science. 207:1980;653-655.
    • (1980) Science , vol.207 , pp. 653-655
    • Debault, L.E.1    Cancilla, P.A.2
  • 23
    • 0014888279 scopus 로고
    • Measurement of brain uptake of radiolabeled substance using a tritiated water internal standard
    • Oldendorf W.H. Measurement of brain uptake of radiolabeled substance using a tritiated water internal standard. Brain Res. 24:1970;372-376.
    • (1970) Brain Res. , vol.24 , pp. 372-376
    • Oldendorf, W.H.1
  • 24
    • 0026502638 scopus 로고
    • The cerebral microvessels in culture, an update
    • Joo F. The cerebral microvessels in culture, an update. J. Neurochem. 58:1992;1-17.
    • (1992) J. Neurochem. , vol.58 , pp. 1-17
    • Joo, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.