Current status and perspectives in the development of camptothecins

Current Pharmaceutical Design

Volumn 8, Issue 27, 2002, Pages 2505-2520

  Zunino, Franco ^a   Dallavalle, Sabrina ^a   Laccabue, Diletta ^a   Beretta, Giovanni ^a   Merlini, Lucio ^a   Pratesi, Graziella ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Antitumor agents; Camptothecin; Topoisomerase I

Indexed keywords

6 [2 (DIMETHYLAMINO)ETHYLAMINO] 3 HYDROXY 7H INDENO[2,1 C]QUINOLIN 7 ONE; 6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; 7 CHLOROMETHYL 10,11 METHYLENEDIOXYCAMPTOTHECIN; 7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 ETHYL 10,11 METHYLENEDIOXYCAMPTOTHECIN; ALBUMIN; ANTINEOPLASTIC AGENT; BELOTECAN; BENZIMIDAZOLE DERIVATIVE; BMS 181176; CAMPTOTHECIN DERIVATIVE; CARBAZOLE DERIVATIVE; CYTOTOXIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; EDOTECARIN; EXATECAN; HOE 33342; IRINOTECAN; LIPOSOME; LURTOTECAN; MACROGOL; MICROSPHERE; N (2 HYDROXYPROPYL)METHACRYLAMIDE; POLYGLACTIN; REBECCAMYCIN; RUBITECAN; TOPOTECAN; TRABECTEDIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA CLEAVAGE; DRUG ACTIVITY; DRUG ADMINISTRATION ROUTE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG RESEARCH; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; GASTROINTESTINAL DISEASE; HEMATOLOGIC DISEASE; HUMAN; MALIGNANT NEOPLASTIC DISEASE; MEDICAL DOCUMENTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; STRUCTURE ACTIVITY RELATION; TARGET CELL; TREATMENT OUTCOME; TUMOR CELL;

ANIMALS; CAMPTOTHECIN; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNOLOGY, PHARMACEUTICAL;

EID: 0036431991     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612023392801     Document Type: Review

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