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Volumn 57, Issue 9, 1997, Pages 1654-1659

Down-regulation of DNA replication in extracts of camptothecin-treated cells: Activation of an S-phase checkpoint?

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; NSC 100800; UNCLASSIFIED DRUG;

EID: 0031007155     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 0028174984 scopus 로고
    • DNA topoisomerases: Essential enzymes and lethal targets
    • Chen, A. Y., and Liu, L. F. DNA topoisomerases: essential enzymes and lethal targets. Annu. Rev. Pharmacol. Toxicol., 34: 191-218, 1994.
    • (1994) Annu. Rev. Pharmacol. Toxicol. , vol.34 , pp. 191-218
    • Chen, A.Y.1    Liu, L.F.2
  • 2
    • 0029144134 scopus 로고
    • Topoisomerase poisons: Harnessing the dark side enzyme mechanism
    • Froelich-Ammon, S. J., and Osheroff, N. Topoisomerase poisons: harnessing the dark side enzyme mechanism. J. Biol. Chem., 270: 21429-21432, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 21429-21432
    • Froelich-Ammon, S.J.1    Osheroff, N.2
  • 4
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothesis
    • Hsiang, Y-H., Lihou, M. G., and Liu, L. F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothesis. Cancer Res., 49: 5077-5087, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5077-5087
    • Hsiang, Y.-H.1    Lihou, M.G.2    Liu, L.F.3
  • 5
    • 0024460479 scopus 로고
    • Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase-I
    • Covey, J. M., Jaxel, C., Kohn, K. W., and Pommier, Y. Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase-I. Cancer Res., 49: 5016-5022, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 5016-5022
    • Covey, J.M.1    Jaxel, C.2    Kohn, K.W.3    Pommier, Y.4
  • 6
    • 0025276858 scopus 로고
    • A model for tumor cell killing by topoisomerase poisons
    • Zhang, H., D'Arpa, P., and Liu, L. F. A model for tumor cell killing by topoisomerase poisons. Cancer Cells, 2: 23-27, 1990.
    • (1990) Cancer Cells , vol.2 , pp. 23-27
    • Zhang, H.1    D'Arpa, P.2    Liu, L.F.3
  • 7
    • 0027139317 scopus 로고
    • Interaction between replication forks and topoisomerase I-DNA cleavable complexes: Studies in a cell-free SV40 DNA replication system
    • Tsao, Y-P., Russo, A., Nyamuswa, G., Silber, R., and Liu, L. F. Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. Cancer Res., 53: 5908-5914, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5908-5914
    • Tsao, Y.-P.1    Russo, A.2    Nyamuswa, G.3    Silber, R.4    Liu, L.F.5
  • 9
    • 0025133118 scopus 로고
    • Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
    • D'Arpa, P., Beardmore, C., and Liu, L. F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res., 50: 6919-6924, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6919-6924
    • D'Arpa, P.1    Beardmore, C.2    Liu, L.F.3
  • 10
    • 0023807621 scopus 로고
    • Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication fork
    • Avemann, K., Knippers, R., Koller, T., and Sago, J. M. Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication fork. Mol. Cell. Biol., 8: 3026-3034, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3026-3034
    • Avemann, K.1    Knippers, R.2    Koller, T.3    Sago, J.M.4
  • 11
    • 0025812689 scopus 로고
    • Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
    • Ryan A. J., Squires, S., Strutt, H. L., and Johnson, R. T. Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res., 19: 3295-3300, 1991.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3295-3300
    • Ryan, A.J.1    Squires, S.2    Strutt, H.L.3    Johnson, R.T.4
  • 12
    • 0026625512 scopus 로고
    • 2 arrest: Altered regulation of p34 cdc2/cyclin B
    • 2 arrest: altered regulation of p34 cdc2/cyclin B. Cancer Res., 52: 1823-1829, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1823-1829
    • Tsao, Y.-P.1    D'Arpa, P.2    Liu, L.F.3
  • 14
    • 0027029077 scopus 로고
    • A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells
    • O'Connor, P. M., and Kohn, K. W. A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells. Semin. Cancer Biol., 3: 409-416, 1992.
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 409-416
    • O'Connor, P.M.1    Kohn, K.W.2
  • 15
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Washington DC
    • Hartwell, L., and Weinert, T. Checkpoints: controls that ensure the order of cell cycle events. Science (Washington DC), 246: 629-634, 1989.
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.1    Weinert, T.2
  • 16
    • 0029085781 scopus 로고
    • A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
    • Paulovich, A. G., and Hartwell, L. H. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell, 82: 841-847, 1995.
    • (1995) Cell , vol.82 , pp. 841-847
    • Paulovich, A.G.1    Hartwell, L.H.2
  • 17
    • 0024441048 scopus 로고
    • Initiation of eukaryotic DNA replication in vitro
    • Stillman, B. Initiation of eukaryotic DNA replication in vitro. Annu. Rev. Cell. Biol., 5: 197-245, 1989.
    • (1989) Annu. Rev. Cell. Biol. , vol.5 , pp. 197-245
    • Stillman, B.1
  • 19
    • 0025187864 scopus 로고
    • The in vitro replication of DNA containing the SV40 origin
    • Hurwitz, J., Dean, F. B., Kwong, A. D., and Lee, S-H. The in vitro replication of DNA containing the SV40 origin. J. Biol. Chem, 265: 18043-18046, 1990.
    • (1990) J. Biol. Chem , vol.265 , pp. 18043-18046
    • Hurwitz, J.1    Dean, F.B.2    Kwong, A.D.3    Lee, S.-H.4
  • 20
    • 0028928548 scopus 로고
    • Regulation of DNA replications in irradiated cells by trans-acting factors
    • Wang, Y., Huq, M. S., Cheng, X., and Iliakis, G. Regulation of DNA replications in irradiated cells by trans-acting factors. Radiat. Res. 142: 169-175, 1995.
    • (1995) Radiat. Res. , vol.142 , pp. 169-175
    • Wang, Y.1    Huq, M.S.2    Cheng, X.3    Iliakis, G.4
  • 21
    • 0030005004 scopus 로고    scopus 로고
    • Evidence for activities inhibiting in trans initiation of DNA replication in extract prepared from irradiated cells
    • Wang, Y., Huq, M. S., and Iliakis, G. Evidence for activities inhibiting in trans initiation of DNA replication in extract prepared from irradiated cells. Radiat. Res., 145: 408-418, 1996.
    • (1996) Radiat. Res. , vol.145 , pp. 408-418
    • Wang, Y.1    Huq, M.S.2    Iliakis, G.3
  • 22
    • 0024851541 scopus 로고
    • Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, α and β
    • Tsurimoto, T., and Stillman, B. Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, α and β. EMBO J., 8: 3883-3889, 1989.
    • (1989) EMBO J. , vol.8 , pp. 3883-3889
    • Tsurimoto, T.1    Stillman, B.2
  • 23
    • 0028245269 scopus 로고
    • Recombinant replication protein A: Expression, complex formation, and functional characterization
    • Henricksen, L. A., Umbrich, C. B., and Wold, M. S., Recombinant replication protein A: expression, complex formation, and functional characterization. J. Biol. Chem., 269: 11121-11132, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11121-11132
    • Henricksen, L.A.1    Umbrich, C.B.2    Wold, M.S.3
  • 24
    • 0001498255 scopus 로고
    • Eukaryotic DNA topoisomerases: Two forms of type I DNA topoisomerases from HeLa cell nuclei
    • Liu, L. F., and Miller, K. G., Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei. Proc. Natl. Acad. Sci. USA, 78: 3487-3491, 1981.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3487-3491
    • Liu, L.F.1    Miller, K.G.2
  • 25
    • 0029976544 scopus 로고    scopus 로고
    • In vitro rejoining of double-strand breaks in cellular DNA by factors present in extracts of HeLa cells
    • Cheong, N., Okayasu, R., Shah, S., Ganguly, T., Mammen, P., and Iliakis, G. In vitro rejoining of double-strand breaks in cellular DNA by factors present in extracts of HeLa cells. Int. J. Radiat. Biol., 69: 665-677, 1996.
    • (1996) Int. J. Radiat. Biol. , vol.69 , pp. 665-677
    • Cheong, N.1    Okayasu, R.2    Shah, S.3    Ganguly, T.4    Mammen, P.5    Iliakis, G.6
  • 26
    • 0026573626 scopus 로고
    • Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc
    • Wang, Y., and Iliakis, G. Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc. Cancer Res., 52: 508-514, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 508-514
    • Wang, Y.1    Iliakis, G.2
  • 27
    • 0027411970 scopus 로고
    • Persistent inhibition of DNA synthesis in irradiated rat embryo fibroblasts expressing the oncogenes H-ras plus v-myc derives from inhibition of replicon initiation and is mitigated by staurosporine
    • Wang, Y., Cheong, N., and Iliakis, G. Persistent inhibition of DNA synthesis in irradiated rat embryo fibroblasts expressing the oncogenes H-ras plus v-myc derives from inhibition of replicon initiation and is mitigated by staurosporine. Cancer Res., 53: 1213-1217, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1213-1217
    • Wang, Y.1    Cheong, N.2    Iliakis, G.3
  • 29
    • 1842311742 scopus 로고
    • Cellular factors required for multiple stages of SV40 DNA replication in vitro
    • Fairman, M. P., and Stillman, B. Cellular factors required for multiple stages of SV40 DNA replication in vitro. EMBO J., 7: 1211-1218, 1988.
    • (1988) EMBO J. , vol.7 , pp. 1211-1218
    • Fairman, M.P.1    Stillman, B.2
  • 30
    • 0023992803 scopus 로고
    • Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA
    • Wold, M. S., and Kelly, T. Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. Proc. Natl. Acad. Sci. USA, 85: 2523-2527, 1988.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2523-2527
    • Wold, M.S.1    Kelly, T.2
  • 31
    • 0028355488 scopus 로고
    • UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein
    • Carty, M. P., Zernik-Kobak, M., McGrath, S. and Dixon, K. UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein. EMBO J., 13: 2114-2123, 1994.
    • (1994) EMBO J. , vol.13 , pp. 2114-2123
    • Carty, M.P.1    Zernik-Kobak, M.2    McGrath, S.3    Dixon, K.4
  • 32
    • 0027428513 scopus 로고
    • The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells
    • Liu, V. F., and Weaver, D. T. The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells. Mol. Cell. Biol., 13: 7222-7231, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7222-7231
    • Liu, V.F.1    Weaver, D.T.2
  • 33
    • 0029970505 scopus 로고    scopus 로고
    • Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts
    • Cheng, X., Cheong, N., Wang, Y. and Iliakis, G. Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia telangiectasia and reduced in aged normal fibroblasts. Radiother. Oncol., 39: 43-52, 1996.
    • (1996) Radiother. Oncol. , vol.39 , pp. 43-52
    • Cheng, X.1    Cheong, N.2    Wang, Y.3    Iliakis, G.4
  • 34
    • 2642625363 scopus 로고
    • Rules of DNA topoisomerases in simian virus 40 DNA replication in vitro
    • Yang, L., Wold, M. S., Li, J. J., Kelly, T. J., and Liu, L. F. Rules of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc. Natl. Acad. Sci. USA, 84: 950-954, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 950-954
    • Yang, L.1    Wold, M.S.2    Li, J.J.3    Kelly, T.J.4    Liu, L.F.5
  • 35
    • 0028094758 scopus 로고
    • Down-regulation of topoisomerase I in mammalian cells following ionizing radiation
    • Boothman, D. A., Fukunaga, N., and Wang, M. Down-regulation of topoisomerase I in mammalian cells following ionizing radiation. Cancer Res., 54: 4618-4626, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4618-4626
    • Boothman, D.A.1    Fukunaga, N.2    Wang, M.3
  • 36
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Washington DC
    • Hartwell, L. H., and Kastan, M. B. Cell cycle control and cancer. Science (Washington DC), 266: 1821-1828, 1994.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 37
    • 0026539144 scopus 로고
    • cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication
    • Dutta, A., and Stillman, B. cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication. EMBO J., 6: 2189-2199, 1992.
    • (1992) EMBO J. , vol.6 , pp. 2189-2199
    • Dutta, A.1    Stillman, B.2
  • 38
    • 0028016304 scopus 로고
    • Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin a complex and DNA-dependent protein kinase
    • Pan, Z-Q., Amin, A. A., Gibbs, E., Niu, H. and Hurwitz, J. Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase. Proc. Natl. Acad. Sci. USA, 91: 8343-8347, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8343-8347
    • Pan, Z.-Q.1    Amin, A.A.2    Gibbs, E.3    Niu, H.4    Hurwitz, J.5
  • 39
    • 0028607553 scopus 로고
    • The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication
    • Brush, G. S., Anderson, C. W., and Kelly, T. J. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc. Natl. Acad. Sci. USA, 91: 12520-12524, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12520-12524
    • Brush, G.S.1    Anderson, C.W.2    Kelly, T.J.3
  • 40
    • 0027941616 scopus 로고
    • Replication protein A mutants lacking phosphorylation sites for p34cdc2 kinase support DNA replication
    • Henricksen, L. A., and Wold, M. S. Replication protein A mutants lacking phosphorylation sites for p34cdc2 kinase support DNA replication. J. Biol. Chem., 269: 24203-24208, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24203-24208
    • Henricksen, L.A.1    Wold, M.S.2
  • 41
    • 0029074504 scopus 로고
    • Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair
    • Pan, Z. Q., Park, C. H., Amin, A. A., Hurwitz, J. and Sancar, A. Phosphorylated and unphosphorylated forms of human single-stranded DNA-binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair. Proc. Natl. Acad. Sci. USA, 92: 4636-4640, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4636-4640
    • Pan, Z.Q.1    Park, C.H.2    Amin, A.A.3    Hurwitz, J.4    Sancar, A.5
  • 42
    • 0029143646 scopus 로고
    • Scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase
    • Boubnov, N. V., and Weaver, D. T. Scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase. Mol. Cell. Biol., 15: 5700-5706, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5700-5706
    • Boubnov, N.V.1    Weaver, D.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.