Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 3496-3501

  Martinez, Eduardo J ^a   Owa, Takashi ^a   Schreiber, Stuart L ^a   Corey, E J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CAMPTOTHECIN; CISPLATIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ETOPOSIDE; MITOMYCIN C; PACLITAXEL; PHTHALASCIDIN; TRABECTEDIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CROSS LINKING; DRUG MECHANISM; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TUMOR GROWTH;

ANTINEOPLASTIC AGENTS, ALKYLATING; BLEOMYCIN; CAMPTOTHECIN; CELL DIVISION; CISPLATIN; CROSS-LINKING REAGENTS; DIOXOLES; DNA TOPOISOMERASES, TYPE I; DNA, NEOPLASM; DOXORUBICIN; ETOPOSIDE; FEMALE; HUMANS; ISOQUINOLINES; MALE; MITOMYCIN; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PACLITAXEL; PHTHALIMIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROISOQUINOLINES; TUMOR CELLS, CULTURED;

EID: 0033616691     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.3496     Document Type: Article

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