-
1
-
-
0026339352
-
Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells
-
Chen AY, Yu C, Potmesil M, Wall ME, Wani MC, Liu LF (1991) Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells. Cancer Res 51: 6039
-
(1991)
Cancer Res
, vol.51
, pp. 6039
-
-
Chen, A.Y.1
Yu, C.2
Potmesil, M.3
Wall, M.E.4
Wani, M.C.5
Liu, L.F.6
-
2
-
-
0022972654
-
Interna; duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
-
Chen C-J, Chin JE, Ueda K, Clark DP, Pastan I, Gottesman MM, Roninson IB (1986) Interna; duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell 47: 381
-
(1986)
Cell
, vol.47
, pp. 381
-
-
Chen, C.-J.1
Chin, J.E.2
Ueda, K.3
Clark, D.P.4
Pastan, I.5
Gottesman, M.M.6
Roninson, I.B.7
-
3
-
-
0028911408
-
In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues
-
Emerson DL, Besterman JM, Brown HR, Evans MG, Leitner PP, Luzzio MJ, Shaffer JE, Sternbach DD, Uehling D, Vuong A (1995) In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res 55: 603
-
(1995)
Cancer Res
, vol.55
, pp. 603
-
-
Emerson, D.L.1
Besterman, J.M.2
Brown, H.R.3
Evans, M.G.4
Leitner, P.P.5
Luzzio, M.J.6
Shaffer, J.E.7
Sternbach, D.D.8
Uehling, D.9
Vuong, A.10
-
4
-
-
0024594687
-
Multifactorial analysis of parameters influencing chemosensitivity of human cancer xenografts in nude mice
-
Fujita F, Fujita M, Taguchi T, Shimozuma K, Sakamoto Y, Kimoto Y, Hirai T (1989) Multifactorial analysis of parameters influencing chemosensitivity of human cancer xenografts in nude mice. Int J Cancer 43: 637
-
(1989)
Int J Cancer
, vol.43
, pp. 637
-
-
Fujita, F.1
Fujita, M.2
Taguchi, T.3
Shimozuma, K.4
Sakamoto, Y.5
Kimoto, Y.6
Hirai, T.7
-
5
-
-
0027939675
-
Combination chemotherapy of BOF-A2, a new 5-FU derivative, with various anticancer agents against human cancer xenografts in nude mice
-
Fujita F, Fujita M, Fujita M, Sakamoto Y (1994) Combination chemotherapy of BOF-A2, a new 5-FU derivative, with various anticancer agents against human cancer xenografts in nude mice. Jpn J Cancer Chemother 21: 1619
-
(1994)
Jpn J Cancer Chemother
, vol.21
, pp. 1619
-
-
Fujita, F.1
Fujita, M.2
Fujita, M.3
Sakamoto, Y.4
-
6
-
-
0026531753
-
A phase II study of CPT-II, a new derivative of camptothecin for previously untreated non-small-cell lung cancer
-
Fukuoka M, Niitani H, Suzuki A, Motomiya M, Hasegawa K, Nishiwaki Y, Kuriyama T, Ariyoshi Y, Negoro S, Masuda N, Nakajima S, Taguchi T. the CPT-11 Lung Cancer Study Group (1992) A phase II study of CPT-II, a new derivative of camptothecin for previously untreated non-small-cell lung cancer. J Clin Oncol 10: 16
-
(1992)
J Clin Oncol
, vol.10
, pp. 16
-
-
Fukuoka, M.1
Niitani, H.2
Suzuki, A.3
Motomiya, M.4
Hasegawa, K.5
Nishiwaki, Y.6
Kuriyama, T.7
Ariyoshi, Y.8
Negoro, S.9
Masuda, N.10
Nakajima, S.11
Taguchi, T.12
-
7
-
-
0023019651
-
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
-
Gerlach JH, Endicott JA, Juranka PF, Henderson G, Sarangi F, Deuchars KL, Ling V (1986) Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance. Nature 324: 485
-
(1986)
Nature
, vol.324
, pp. 485
-
-
Gerlach, J.H.1
Endicott, J.A.2
Juranka, P.F.3
Henderson, G.4
Sarangi, F.5
Deuchars, K.L.6
Ling, V.7
-
8
-
-
0026772298
-
Effect of P-glycoprotein expression on the accumulation and cytotoxicity of Topotecan (SK&F 104864), a new camptothecin analogue
-
Hendricks CB, Rowinsky EK, Grochow LB, Donehower RC, Kaufmann SH (1992) Effect of P-glycoprotein expression on the accumulation and cytotoxicity of Topotecan (SK&F 104864), a new camptothecin analogue. Cancer Res 52: 2268
-
(1992)
Cancer Res
, vol.52
, pp. 2268
-
-
Hendricks, C.B.1
Rowinsky, E.K.2
Grochow, L.B.3
Donehower, R.C.4
Kaufmann, S.H.5
-
9
-
-
0026487210
-
Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors
-
Houghton PJ, Cheshire PJ, Myers L, Stewart CF, Synold TW, Houghton JA (1992) Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors. Cancer Chemother Pharmacol 31: 229
-
(1992)
Cancer Chemother Pharmacol
, vol.31
, pp. 229
-
-
Houghton, P.J.1
Cheshire, P.J.2
Myers, L.3
Stewart, C.F.4
Synold, T.W.5
Houghton, J.A.6
-
10
-
-
0030785681
-
DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant
-
Joto N, Ishii M, Minami M, Kuga H, Mitsui I, Tohgo A (1997) DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant. Int J Cancer 72: 680
-
(1997)
Int J Cancer
, vol.72
, pp. 680
-
-
Joto, N.1
Ishii, M.2
Minami, M.3
Kuga, H.4
Mitsui, I.5
Tohgo, A.6
-
11
-
-
0012019581
-
Total synthesis of the novel water soluble camptothecin analog GI147211C, a potent topoisomerase I inhibitor
-
Kang MC, Bankston DD, Erickson GA, Fang FG, Lackey JW, Lewis GS, Lichty ME, Lowery MW, Mader C, McDougald DL, Mook RA, Partrige JJ, Xie S (1991) Total synthesis of the novel water soluble camptothecin analog GI147211C, a potent topoisomerase I inhibitor (abstract). Proc Am Assoc Cancer Res 34: 332
-
(1991)
Proc Am Assoc Cancer Res
, vol.34
, pp. 332
-
-
Kang, M.C.1
Bankston, D.D.2
Erickson, G.A.3
Fang, F.G.4
Lackey, J.W.5
Lewis, G.S.6
Lichty, M.E.7
Lowery, M.W.8
Mader, C.9
McDougald, D.L.10
Mook, R.A.11
Partrige, J.J.12
Xie, S.13
-
12
-
-
0025084410
-
Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: Characterization and mechanism of resistance
-
Kanzawa F, Sugimoto Y, Minato K, Kasahara K, Bungo M, Nakagawa K, Fujiwara Y, Liu LF, Saijo N (1990) Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res 50: 5919
-
(1990)
Cancer Res
, vol.50
, pp. 5919
-
-
Kanzawa, F.1
Sugimoto, Y.2
Minato, K.3
Kasahara, K.4
Bungo, M.5
Nakagawa, K.6
Fujiwara, Y.7
Liu, L.F.8
Saijo, N.9
-
13
-
-
0025996996
-
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
-
Kawato Y, Aonuma M, Hirota Y, Kuga H, Sato K (1991) Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 51: 4187
-
(1991)
Cancer Res
, vol.51
, pp. 4187
-
-
Kawato, Y.1
Aonuma, M.2
Hirota, Y.3
Kuga, H.4
Sato, K.5
-
14
-
-
0025785082
-
Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice
-
Kawato Y, Furuta T, Aonuma M, Yasuoka M, Yokokura T, Matsumoto K (1991) Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice. Cancer Chemother Pharmacol 28: 192
-
(1991)
Cancer Chemother Pharmacol
, vol.28
, pp. 192
-
-
Kawato, Y.1
Furuta, T.2
Aonuma, M.3
Yasuoka, M.4
Yokokura, T.5
Matsumoto, K.6
-
15
-
-
0026099599
-
Synthesis of water-soluble (aminoalkyl) camptothecin analogues: Inhibition of topoisomerase I and antitumor activity
-
Kingsbury WD, Boehm JC, Jakas DR, Holden KG, Hecht SM, Gallagher G, Caranfa MJ, McCabe FL, Faucette LF, Johnson RK, Hertzberg RP (1991) Synthesis of water-soluble (aminoalkyl) camptothecin analogues: inhibition of topoisomerase I and antitumor activity. J Med Chem 34: 98
-
(1991)
J Med Chem
, vol.34
, pp. 98
-
-
Kingsbury, W.D.1
Boehm, J.C.2
Jakas, D.R.3
Holden, K.G.4
Hecht, S.M.5
Gallagher, G.6
Caranfa, M.J.7
McCabe, F.L.8
Faucette, L.F.9
Johnson, R.K.10
Hertzberg, R.P.11
-
16
-
-
0012019581
-
Novel water-soluble camptothecin analogs as inhibitors of topoisomerase I
-
Luzzio MJ, Besterman JM, Evans MG, Lackey KE, Leitner P, Peel MR, Sisco JM, Sternbach DD, Tong T, Uehling DE (1993) Novel water-soluble camptothecin analogs as inhibitors of topoisomerase I (abstract). Proc Am Assoc Cancer Res 34: 332
-
(1993)
Proc Am Assoc Cancer Res
, vol.34
, pp. 332
-
-
Luzzio, M.J.1
Besterman, J.M.2
Evans, M.G.3
Lackey, K.E.4
Leitner, P.5
Peel, M.R.6
Sisco, J.M.7
Sternbach, D.D.8
Tong, T.9
Uehling, D.E.10
-
17
-
-
0026680292
-
CPT-11: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer
-
Masuda N, Fukuoka M, Kusunoki Y, Matsui K, Takifuji N, Kudoh S, Negoro S, Nishioka M, Nakagawa K, Takada M (1992) CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer. J Clin Oncol 10: 1225
-
(1992)
J Clin Oncol
, vol.10
, pp. 1225
-
-
Masuda, N.1
Fukuoka, M.2
Kusunoki, Y.3
Matsui, K.4
Takifuji, N.5
Kudoh, S.6
Negoro, S.7
Nishioka, M.8
Nakagawa, K.9
Takada, M.10
-
18
-
-
0027082880
-
CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer
-
Masuda N, Fukuoka M, Takada M, Kusunoki Y, Negoro S, Matsui K, Kudoh S, Takifuji M, Nakagawa K, Kishimoto S (1992) CPT-11 in combination with cisplatin for advanced non-small-cell lung cancer. J Clin Oncol 10: 1775
-
(1992)
J Clin Oncol
, vol.10
, pp. 1775
-
-
Masuda, N.1
Fukuoka, M.2
Takada, M.3
Kusunoki, Y.4
Negoro, S.5
Matsui, K.6
Kudoh, S.7
Takifuji, M.8
Nakagawa, K.9
Kishimoto, S.10
-
19
-
-
0029150444
-
A new water-soluble camptothecin derivative. DX-8951f. exhibits potent antitumor activity against human tumors in vitro and in vivo
-
Mitsui I, Kumazawa E, Hirota Y, Aonuma M, Sugimori M, Ohsuki S, Uoto K, Ejima A, Terasawa H, Sato K (1995) A new water-soluble camptothecin derivative. DX-8951f. exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res 86: 776
-
(1995)
Jpn J Cancer Res
, vol.86
, pp. 776
-
-
Mitsui, I.1
Kumazawa, E.2
Hirota, Y.3
Aonuma, M.4
Sugimori, M.5
Ohsuki, S.6
Uoto, K.7
Ejima, A.8
Terasawa, H.9
Sato, K.10
-
20
-
-
0000107302
-
Phase II study of CPT-11, a new camptothecin derivative, in small cell lung cancer (SCLC)
-
Negoro S, Fukuoka M, Niitani H, et al (1991) Phase II study of CPT-11, a new camptothecin derivative, in small cell lung cancer (SCLC) (abstract). Proc Am Soc Clin Oncol 10: 241
-
(1991)
Proc Am Soc Clin Oncol
, vol.10
, pp. 241
-
-
Negoro, S.1
Fukuoka, M.2
Niitani, H.3
-
21
-
-
0027194943
-
Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
-
Shimada Y, Yoshino M, Wakui A, Nakao I, Futatsuki K, Sakata Y, Kambe M, Taguchi T, Ogawa N, the CPT-11 Gastrointestinal Cancer Study Group (1993) Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. J Clin Oncol 11: 909
-
(1993)
J Clin Oncol
, vol.11
, pp. 909
-
-
Shimada, Y.1
Yoshino, M.2
Wakui, A.3
Nakao, I.4
Futatsuki, K.5
Sakata, Y.6
Kambe, M.7
Taguchi, T.8
Ogawa, N.9
-
22
-
-
0001524545
-
Clinical study of CPT-11, camptothecin derivative, on gynecological malignancy
-
Takeuchi S, Takamizawa H, Takeda Y, Okawa T, Tamaya T, Noda K, Sugawa T, Sekiba K, Yakushiji M, Taguchi T (1991) Clinical study of CPT-11, camptothecin derivative, on gynecological malignancy (abstract). Proc Am Soc Clin Oncol 10: 189
-
(1991)
Proc Am Soc Clin Oncol
, vol.10
, pp. 189
-
-
Takeuchi, S.1
Takamizawa, H.2
Takeda, Y.3
Okawa, T.4
Tamaya, T.5
Noda, K.6
Sugawa, T.7
Sekiba, K.8
Yakushiji, M.9
Taguchi, T.10
-
23
-
-
0000177763
-
Late phase II study of CPT-11, topoisomerase I inhibitor, in advanced cervical carcinoma (CC)
-
Takeuchi S, Noda K, Yakushiji M, et al (1992) Late phase II study of CPT-11, topoisomerase I inhibitor, in advanced cervical carcinoma (CC) (abstract). Proc Am Soc Clin Oncol 11: 224
-
(1992)
Proc Am Soc Clin Oncol
, vol.11
, pp. 224
-
-
Takeuchi, S.1
Noda, K.2
Yakushiji, M.3
-
24
-
-
0025827281
-
CPT-11 converting enzyme from rat serum: Purification and some properties
-
Tsuji T, Kaneda N, Kada K, Yokokura T, Yoshimoto T, Tsuru D (1991) CPT-11 converting enzyme from rat serum: purification and some properties. J Pharmacobio-Dyn 14: 341
-
(1991)
J Pharmacobio-Dyn
, vol.14
, pp. 341
-
-
Tsuji, T.1
Kaneda, N.2
Kada, K.3
Yokokura, T.4
Yoshimoto, T.5
Tsuru, D.6
-
25
-
-
0023888724
-
Mechanism of multidrug resistance and implications for therapy
-
Tsuruo T (1988) Mechanism of multidrug resistance and implications for therapy. Jpn J Cancer Res 79: 285
-
(1988)
Jpn J Cancer Res
, vol.79
, pp. 285
-
-
Tsuruo, T.1
|