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Volumn 30, Issue 1 SUPPL. B, 2002, Pages

Toll-like receptors

Author keywords

Bacterial proteins; Cell surface signal transduction; Immunity; Inflammation; Innate receptors; Lipopolysaccharide; Macrophage activation; Sepsis; Shock; Toll

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; LIPOPROTEIN; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 0036159869     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200201001-00001     Document Type: Conference Paper
Times cited : (257)

References (209)
  • 11
    • 0014883341 scopus 로고
    • Changing ecology of bacterial infections as related to antibacterial therapy
    • (1970) J Infect Dis , vol.122 , pp. 419-431
    • Finland, M.1
  • 13
    • 84943437832 scopus 로고
    • Bacillus coli sepsis: A clinical study of twenty-eight cases of bloodstream infection by the colon bacillus
    • (1924) JAMA , vol.82 , pp. 1430-1433
    • Felty, A.1    Keefer, C.2
  • 14
    • 0001740169 scopus 로고
    • Bloodstream infections in urology: Report of 82 cases
    • (1929) J Urol , vol.21 , pp. 527-566
    • Scott, W.1
  • 18
    • 0014542423 scopus 로고
    • Infections due to Gram-negative organisms: An analysis of 860 patients with bacteremia at the University of Minnesota Medical Center, 1958-1966
    • (1969) Medicine (Baltimore) , vol.48 , pp. 307-332
    • DuPont, H.L.1    Spink, W.W.2
  • 23
  • 28
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3
  • 33
    • 0025803877 scopus 로고
    • The polarity of the dorsoventral axis in the Drosophila embryo is defined by an extracellular signal
    • (1991) Cell , vol.65 , pp. 725-735
    • Stein, D.1    Roth, S.2    Vogelsang, E.3
  • 34
    • 0032033030 scopus 로고    scopus 로고
    • Proteolytic processing of the Drosophila Spatzle protein by easter generates a dimeric NGF-like molecule with ventralising activity
    • (1998) Mech Dev , vol.72 , pp. 141-148
    • DeLotto, Y.1    DeLotto, R.2
  • 38
    • 0026486817 scopus 로고
    • Cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates
    • (1992) Cell , vol.71 , pp. 613-621
    • Geisler, R.1    Bergmann, A.2    Hiromi, Y.3
  • 39
    • 0026491071 scopus 로고
    • Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins
    • (1992) Cell , vol.71 , pp. 623-635
    • Kidd, S.1
  • 46
    • 2042461996 scopus 로고    scopus 로고
    • Molecular cloning and functional characterization of chicken Toll-like receptors: A single chicken Toll covers multiple molecular patterns
    • (2001) J Biol Chem , vol.4 , pp. 4
    • Fukui, A.1    Inoue, N.2    Matsumoto, M.3
  • 47
    • 0029867832 scopus 로고    scopus 로고
    • Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14
    • (1996) Genomics , vol.32 , pp. 486-488
    • Taguchi, T.1    Mitcham, J.L.2    Dower, S.K.3
  • 50
    • 0032100444 scopus 로고    scopus 로고
    • Cloning and characterization of two Toll/ interleukin-1 receptor-like genes TIL3 and TIL4: Evidence for a multi-gene receptor family in humans
    • (1998) Blood , vol.91 , pp. 4020-4027
    • Chaudhary, P.M.1    Ferguson, C.2    Nguyen, V.3
  • 56
    • 0034304668 scopus 로고    scopus 로고
    • The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defence
    • (2000) Biochem Soc Trans , vol.28 , pp. 557-563
    • O'Neill, L.1
  • 59
    • 0034123135 scopus 로고    scopus 로고
    • Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
    • (2000) J Immunol , vol.164 , pp. 5998-6004
    • Muzio, M.1    Bosisio, D.2    Polentarutti, N.3
  • 60
    • 0034646695 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates NF-kappaB through Toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells: Differential expression of TLR-4 and TLR-2 in endothelial cells
    • (2000) J Biol Chem , vol.275 , pp. 11058-11063
    • Faure, E.1    Equils, O.2    Sieling, P.A.3
  • 61
    • 0034669971 scopus 로고    scopus 로고
    • Toll-like receptor 4, but not Toll-like receptor 2, is a signaling receptor for escherichia and salmonella lipopolysaccharides
    • (2000) J Immunol , vol.165 , pp. 5780-5787
    • Tapping, R.I.1    Akashi, S.2    Miyake, K.3
  • 62
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens
    • (2001) J Exp Med , vol.194 , pp. 863-870
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3
  • 66
    • 0034661645 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 2 on gammadelta T cells bearing invariant Vgamma6/ Vdeltal induced by Escherichia coli infection in mice
    • (2000) J Immunol , vol.165 , pp. 931-940
    • Mokuno, Y.1    Matsuguchi, T.2    Takano, M.3
  • 70
    • 0034651729 scopus 로고    scopus 로고
    • Human Toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide
    • (2000) J Immunol , vol.164 , pp. 2064-2069
    • Flo, T.H.1    Halaas, O.2    Lien, E.3
  • 73
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • (1999) J Biol Chem , vol.274 , pp. 7611-7614
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3
  • 74
    • 0034177888 scopus 로고    scopus 로고
    • Cutting edge: Cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages
    • (2000) J Immunol , vol.164 , pp. 3471-3475
    • Akashi, S.1    Shimazu, R.2    Ogata, H.3
  • 78
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3
  • 82
  • 83
    • 0034662239 scopus 로고    scopus 로고
    • Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2
    • (2000) J Immunol , vol.165 , pp. 618-622
    • Hirschfeld, M.1    Ma, Y.2    Weis, J.H.3
  • 91
    • 0035796406 scopus 로고    scopus 로고
    • Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
    • (2001) J Exp Med , vol.194 , pp. 79-88
    • Schromm, A.B.1    Lien, E.2    Henneke, P.3
  • 93
    • 0035253732 scopus 로고    scopus 로고
    • MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components
    • (2001) J Immunol , vol.166 , pp. 1938-1944
    • Dziarski, R.1    Wang, Q.2    Miyake, K.3
  • 94
    • 0034617274 scopus 로고    scopus 로고
    • Cellular events mediated by lipopolysaccharide-stimulated Toll-like receptor 4
    • MD-2 is required for activation of mitogen-activated protein kinases and Elk-1
    • (2000) J Biol Chem , vol.275 , pp. 20861-20866
    • Yang, H.1    Young, D.W.2    Gusovsky, F.3
  • 109
    • 0035871626 scopus 로고    scopus 로고
    • Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
    • (2001) J Immunol , vol.166 , pp. 5161-5167
    • Lehner, M.D.1    Morath, S.2    Michelsen, K.S.3
  • 114
    • 0035879283 scopus 로고    scopus 로고
    • Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
    • (2001) J Immunol , vol.167 , pp. 987-994
    • Bulut, Y.1    Faure, E.2    Thomas, L.3
  • 118
    • 0034443265 scopus 로고    scopus 로고
    • Maturation of human dendritic cells by cell wall skeleton of mycobacterium bovis bacillus calmette-Guerin: Involvement of Toll-like receptors
    • (2000) Infect Immun , vol.68 , pp. 6883-6890
    • Tsuji, S.1    Matsumoto, M.2    Takeuchi, O.3
  • 124
    • 0034283666 scopus 로고    scopus 로고
    • Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids
    • (2000) J Immunol , vol.165 , pp. 2683-2693
    • Schröder, N.W.1    Opitz, B.2    Lamping, N.3
  • 126
    • 0034912422 scopus 로고    scopus 로고
    • Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2
    • (2001) Infect Immun , vol.69 , pp. 4951-4957
    • Sugawara, S.1    Yang, S.2    Iki, K.3
  • 128
    • 0035087367 scopus 로고    scopus 로고
    • Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through Toll-Like receptor 2
    • (2001) Infect Immun , vol.69 , pp. 2230-2236
    • Ingalls, R.R.1    Lien, E.2    Golenbock, D.T.3
  • 129
    • 0035170049 scopus 로고    scopus 로고
    • A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via Toll-like receptor (TLR) 2 but not via TLR4/MD2
    • (2001) J Infect Dis , vol.183 , pp. 89-96
    • Pridmore, A.C.1    Wyllie, D.H.2    Abdillahi, F.3
  • 130
    • 0035877013 scopus 로고    scopus 로고
    • An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
    • (2001) J Immunol , vol.166 , pp. 7128-7135
    • Li, M.1    Carpio, D.F.2    Zheng, Y.3
  • 131
    • 0035910470 scopus 로고    scopus 로고
    • A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway
    • (2001) J Biol Chem , vol.276 , pp. 1873-1880
    • Lien, E.1    Chow, J.C.2    Hawkins, L.D.3
  • 133
    • 0035313274 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule
    • (2001) J Immunol , vol.166 , pp. 4620-4626
    • Shoham, S.1    Huang, C.2    Chen, J.M.3
  • 137
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • (2001) J Biol Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3
  • 138
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial flagellin activates basolaterally expressed tlr5 to induce epithelial proinflammatory gene expression
    • (2001) J Immunol , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3
  • 148
    • 0032530736 scopus 로고    scopus 로고
    • Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: Correlation to disease progression and clinical events
    • (1998) Blood , vol.92 , pp. 2084-2092
    • Lien, E.1    Aukrust, P.2    Sundan, A.3
  • 149
    • 0035884979 scopus 로고    scopus 로고
    • Mycobacteria-induced TNF-alpha and IL-10 formation by human macrophages is differentially regulated at the level of mitogen-activated protein kinase activity
    • (2001) J Immunol , vol.167 , pp. 3339-3345
    • Reiling, N.1    Blumenthal, A.2    Flad, H.D.3
  • 153
    • 0030443235 scopus 로고    scopus 로고
    • Chemical characteristics of Staphylococcus aureus molecules that have CD14-dependent cell-stimulating activity
    • (1996) J Immunol , vol.157 , pp. 5112-5117
    • Kusunoki, T.1    Wright, S.D.2
  • 155
    • 0028894798 scopus 로고
    • Activation of human monocytes by streptococcal rhamnose glucose polymers is mediated by CD14 antigen, and mannan binding protein inhibits TNF-alpha release
    • (1995) J Immunol , vol.154 , pp. 851-860
    • Soell, M.1    Lett, E.2    Holveck, F.3
  • 158
    • 15444352709 scopus 로고    scopus 로고
    • Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide
    • (1998) J Immunol , vol.160 , pp. 5455-5464
    • Sellati, T.J.1    Bouis, D.A.2    Kitchens, R.L.3
  • 159
    • 0033566734 scopus 로고    scopus 로고
    • Activation of human monocytic cells by Borrelia burgdorferi and Treponema pallidum is facilitated by CD14 and correlates with surface exposure of spirochetal lipoproteins
    • (1999) J Immunol , vol.163 , pp. 2049-2056
    • Sellati, T.J.1    Bouis, D.A.2    Caimano, M.J.3
  • 161
  • 165
    • 0034292364 scopus 로고    scopus 로고
    • Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B
    • (2000) J Immunol , vol.165 , pp. 3541-3544
    • Jiang, Q.1    Akashi, S.2    Miyake, K.3
  • 166
    • 0023026362 scopus 로고
    • Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide
    • (1986) J Exp Med , vol.164 , pp. 1876-1888
    • Wright, S.D.1    Jong, M.T.C.2
  • 167
    • 0024590613 scopus 로고
    • CR3 (CD11b/CD18) expresses one binding Site for Arg-Gly-Asp-containing peptides and a second site for bacterial lipopolysaccharide
    • (1989) J Exp Med , vol.169 , pp. 175-183
    • Wright, S.D.1    Levin, S.M.2    Jong, M.T.3
  • 176
  • 183
    • 0033634977 scopus 로고    scopus 로고
    • TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
    • (2000) Mol Cell , vol.5 , pp. 649-658
    • Takaesu, G.1    Kishida, S.2    Hiyama, A.3
  • 187
    • 0035865249 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta
    • (2001) J Immunol , vol.166 , pp. 2651-2657
    • Seki, E.1    Tsutsui, H.2    Nakano, H.3
  • 194
    • 0035881949 scopus 로고    scopus 로고
    • Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4
    • (2001) J Immunol , vol.167 , pp. 2257-2267
    • Medvedev, A.E.1    Henneke, P.2    Schromm, A.3
  • 195
    • 0032079326 scopus 로고    scopus 로고
    • Reduced ex vivo interleukin-8 production by neutrophils in septic and nonseptic systemic inflammatory response syndrome
    • (1998) Blood , vol.91 , pp. 3439-3446
    • Marie, C.1    Muret, J.2    Fitting, C.3
  • 196
    • 0030036614 scopus 로고    scopus 로고
    • Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: Identification of interleukin-10 as a major functional deactivator of human monocytes
    • (1996) J Exp Med , vol.184 , pp. 51-60
    • Brandtzaeg, P.1    Osnes, L.2    Ovstebo, R.3
  • 197
    • 20244384395 scopus 로고    scopus 로고
    • Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression
    • (2000) J Immunol , vol.164 , pp. 3476-3479
    • Nomura, F.1    Akashi, S.2    Sakao, Y.3
  • 198
    • 0034671772 scopus 로고    scopus 로고
    • Synergy and cross-tolerance between Toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways
    • (2000) J Immunol , vol.165 , pp. 7096-7101
    • Sato, S.1    Nomura, F.2    Kawai, T.3
  • 199
    • 0035500281 scopus 로고    scopus 로고
    • Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli
    • (2001) J Immunol , vol.167 , pp. 5278-5285
    • Martin, M.1    Katz, J.2    Vogel, S.N.3
  • 201
    • 0034043956 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: Dysregulation of cytokine, chemokine, and Toll-like receptor 2 and 4 gene expression
    • (2000) J Immunol , vol.164 , pp. 5564-5574
    • Medvedev, A.E.1    Kopydlowski, K.M.2    Vogel, S.N.3
  • 204
    • 0025831103 scopus 로고
    • Inhibition of endotoxin-induced interleukin-6 production by synthetic lipid A partial structures in human peripheral blood mononuclear cells
    • (1991) Infect Immun , vol.59 , pp. 4655-4664
    • Wang, M.H.1    Flad, H.D.2    Feist, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.