Cloning and characterization of two toll/interleukin-1 receptor-like genes TIL3 and TIL4: Evidence for a multi-gene receptor family in humans

Blood

Volumn 91, Issue 11, 1998, Pages 4020-4027

  Chaudhary, Preet M ^a   Ferguson, Camari ^a   Nguyen, Vilaska ^a   Nguyen, Oanh ^a   Massa, Hillary F ^a   Eby, Michael ^a   Jasmin, Alan ^a   Trask, Barbara J ^a   Hood, Leroy ^a   Nelson, Peter S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR;

ARTICLE; CHROMOSOME MAP; EMBRYO DEVELOPMENT; FLUORESCENCE IN SITU HYBRIDIZATION; GENE ACTIVATION; GENETIC ANALYSIS; GENETIC REGULATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TANDEM REPEAT; TISSUE DISTRIBUTION;

EID: 0032100444     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.11.4020.411a44_4020_4027     Document Type: Article

References (49)

1. Hashimoto C, Hudson KL, Andersen KV: The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 52:269, 1988
2. Hashimoto C, Gerttula S, Anderson KV: Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: Importance of transmembrane signaling for dorsal-ventral pattern formation. Development 111:1021, 1991
3. Dinarello CA: The interleukin-1 family: 10 years of discovery. FASEB J 8:1314, 1994
4. Gay NJ, Keith FJ: Drosophila Toll and IL-1 receptor. Nature 351:355, 1991 (letter)
5. Kobe B, Deisenhofer J: Proteins with leucine-rich repeats. Curr Opin Struct Biol 5:409, 1995
6. Wasserman SA: A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B. Mol Biol Cell 4:767, 1993
7. Geisler R, Bergmann A, Hiromi Y, Nusslein-Volhard C: Cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Cell 71:613, 1992
8. Rosetto M, Engstrom Y, Baldari CT, Telford JL, Hultmark D: Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line. Biochem Biophys Res Commun 209:111, 1995
9. Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA: The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973, 1996
10. Staskawicz BJ, Ausubel FM, Baker BJ, Ellis JG, Jones JD: Molecular genetics of plant disease resistance. Science 268:661, 1995
11. Baeuerle PA, Henkel T: Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12:141, 1994
12. Heguy A, Baldari CT, Macchia G, Telford JL, Melli M: Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction. J Biol Chem 267:2605, 1992
13. Schneider DS, Hudson KL, Lin TY, Anderson KV: Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo. Genes Dev 5:797, 1991
14. Winans KA, Hashimoto C: Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein. Mol Biol Cell 6:587, 1995
15. Medzhitov R, Preston-Hurlburt P, Janeway Jr CA: A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388:394, 1997
16. Taguchi T, Mitcham JL, Dower SK, Sims JE, Testa JR: Chromosomal location of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14. Genomics 32:486, 1996
17. Mitcham JL, Parnet P, Bonnert TP, Garka KE, Gerhart MJ, Slack JL, Gayle MA, Dower SK, Sims JE: T1/ST2 signalling establishes it as member of an expanding interleukin-1 receptor family. J Biol Chem 271:5777, 1996
18. Eldon E, Kooyer S, D'Evelyn D, Duman M, Lawinger P, Botas J, Bellen H: The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 120:885, 1994
19. Chiang C, Beachy PA: Expression of a novel Toll-like gene spans the parasegment boundary and contributes to hedgehog function in the adult eye of Drosophila. Mech Dev 47:225, 1994
20. Maniatis T, Fritsch EF, Sambrook J: Molecular Cloning: A Laboratory Manual (ed 2). Cold Spring Harbor, NY, Cold Spring Harbor Press, 1989
21. Trask BJ: Fluorescence in situ hybridization. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1997
22. Wise CA, Clines GA, Massa H, Trask BJ, Lovett M: Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family. Genome Res 7:10, 1997
23. Berberich I, Shu GL, Clark EA: Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B. J Immunol 153:4357, 1994
24. Kozak M: An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res 15:8125, 1987
25. Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S: Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. DNA Res 1:27, 1994
26. Keith FJ, Gay NJ: The Drosophila membrane receptor Toll can function to promote cellular adhesion. EMBO J 9:4299, 1990
27. Lopez JA, Chung DW, Fujikawa K, Hagen FS, Davie EW, Roth GJ: The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence. Proc Natl Acad Sci USA 85:2135, 1988
28. Hickey MJ, Williams SA, Roth GJ: Human platelet glycoprotein IX: An adhesive prototype of leucine-rich glycoproteins with flank-center-flank structures. Proc Natl Acad Sci USA 86:6773, 1989
29. Takahashi N, Takahashi Y, Putnam FW: Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serum. Proc Natl Acad Sci USA 82:1906, 1985
30. Myers KA, Rahi-Saund V, Davison MD, Young JA, Cheater AJ, Stem PL: Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucinerich repeats. J Biol Chem 269:9319, 1994
31. Harmon JT, Jamieson GA: The glycocalicin portion of platelet glycoprotein Ib expresses both high and moderate affinity receptor sites for thrombin. A soluble radioreceptor assay for the interaction of thrombin with platelets. J Biol Chem 261:13224, 1986
32. Leung K, Betts JC, Xu L, Nabel GJ: The cytoplasmic domain of the interleukin-1 receptor is required for nuclear factor-kappa B signal transduction. J Biol Chem 269:1579, 1994
33. Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, Camonis JH, Wallach D: Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects. J Biol Chem 270:387, 1995
34. Chinnaiyan AM, O'Rourke K, Yu GL, Lyons RH, Garg M, Duan DR, Xing L, Gentz R, Ni J, Dixit VM: Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274:990, 1996
35. Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF: A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 95:588, 1998
36. Belvin MP, Anderson KV: A conserved signaling pathway: The Drosophila toll-dorsal pathway. Ann Rev Cell Dev Biol 12:393, 1996
37. Lewis C, Mazzei G, Shaw A: Monoclonal antibodies reacting with the interleukin 1 receptor define a multi-molecular complex. Eur J Immunol 20:207, 1990
38. Greenfeder SA, Nunes P, Kwee L, Labow M, Chizzonite RA, Ju G: Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J Biol Chem 270:13757, 1995
39. Cao Z, Henzel WJ, Gao X: IRAK: A kinase associated with the interleukin-1 receptor. Science 271:1128, 1996
40. Muzio M, Ni J, Feng P, Dixit VM: IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278:1612, 1997
41. Stancovski I, Baltimore D: NF-kappaB activation: The I kappaB kinase revealed? Cell 91:299, 1997
42. Guida S, Heguy A, Melli M: The chicken IL-1 receptor: Differential evolution of the cytoplasmic and extracellular domains. Gene 111:239, 1992
43. Croston GE, Cao Z, Goeddel DV: NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. J Biol Chem 270:16514, 1995
44. Kishimoto T, Akira S, Narazaki M, Taga T: Interleukin-6 family of cytokines and gp130. Blood 86:1243, 1995
45. Kuno K, Okamoto S, Hirose K, Murakami S, Matsushima K: Structure and function of the intracellular portion of the mouse interleukin 1 receptor (type I). Determining the essential region for transducing signals to activate the interleukin 8 gene. J Biol Chem 268:13510, 1993
46. Buchanan SG, Gay NJ: Structural and functional diversity in the leucine-rich repeat family of proteins. Prog Biophys Mol Biol 65:1, 1996
47. Lopez JA, Chung DW, Fujikawa K, Hagen FS, Papayannopoulou T, Roth GJ: Cloning of the alpha chain of human platelet glycoprotein Ib: A transmembrane protein with homology to leucinerich alpha 2-glycoprotein. Proc Natl Acad Sci USA 84:5615, 1987
48. Rusch J, Levine M: Regulation of the dorsal morphogen by the Toll and torso signaling pathways: A receptor tyrosine kinase selectively masks transcriptional repression. Genes Dev 8:1247, 1994
49. Thompson JD, Higgins DG, Gibson TJ: CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673, 1994