Diverse actions of ovarian steroids in the serotonin neural system

Frontiers in Neuroendocrinology

Volumn 23, Issue 1, 2002, Pages 41-100

  Bethea, Cynthia L ^a,b   Lu, Nick Z ^a,b   Gundlah, Chrisana ^a   Streicher, John M ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; PROGESTERONE; PROGESTERONE RECEPTOR;

AROUSAL; COGNITION; NEUROENDOCRINOLOGY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; REVIEW; RHOMBENCEPHALON; SATIETY; SEROTONIN BRAIN LEVEL; SEROTONINERGIC NERVE;

EID: 0036159513     PISSN: 00913022     EISSN: None     Source Type: Journal    
DOI: 10.1006/frne.2001.0225     Document Type: Article

References (344)

1. Studies of monoamine oxidases. Inhibition of bovine brain MAO in intact mitochondria by selective inhibitors
2. Preoptic/anterior hypothalamic neurons: Thermosensitivity in wakefulness and non rapid eye movement sleep
3. Involvement of the 5HT2 receptor in the 5HT receptor-mediated stimulation of prolactin release
4. 17β-Estradiol rapidly decreases 5-HT1A receptor function in rat hippocampus in vitro: Role of estrogen receptor
5. Estrogen-regulated progestin receptors are found in the midbrain raphe but not hippocampus of estrogen receptor alpha (ER alpha) gene-disrupted mice
6. Estradiol regulation of 5HT neurons in the dorsal raphe of the rat differs from the monkey: An analysis of tryptophan hydroxylase mRNA levels
7. Immunocytochemical localization of nuclear estrogen receptors and progestin receptors within the rat dorsal raphe nucleus
8. Phenotypic identification of ovarian steroid target cells in the rodent dorsal raphe and central gray
9. Pubertal changes in hormone levels and depression in girls
10. Variability in the 5-HT(2A) receptor gene is associated with seasonal pattern in major depression
11. Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors
12. Opposite modulatory effects of ovarian hormones on rat brain dopamine and serotonin transporters
13. A longitudinal analysis of the association between menopause and depression: Results from the Massachusetts Women's Health Study
14. The primate serotonergic system: A review of human and animal studies and a report on Macaca fascicularis
15. Cellular localization of the 5-HT1A receptor in primate brain neurons and glial cells
16. An autoradiographic analysis of the differential ascending projections of the dorsal raphe and median raphe nuclei in the rat
17. cDNA cloning of human liver monoamine oxidase A and B: Molecular basis of differences in enzymatic properties
18. Role of the hypothalamic paraventricular nucleus in 5-HT 1A, 5-HT 2A and 5-HT 2C receptor-mediated oxytocin, prolactin and ACTH/corticosterone responses
19. Hypothalamic paraventricular nucleus lesions differentially affect serotonin-1A (5HT-1A) and 5HT2 receptor agonist-induced oxytocin, prolactin and corticosterone responses
20. Paraventricular nucleus controls 5HT2C receptor-mediated corticosterone and prolactin but not oxytocin and penile erection responses
21. Blunting of neuroendocrine responses to infusion of L-tryptophan in women with perimenstrual mood change
22. Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins
23. Norepinephrine and serotonin transporters. Molecular targets of antidepressant drugs
24. Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A
25. Colocalization of progestin receptors with serotonin in raphe neurons of macaque
26. Regulation of progestin receptors in raphe neurons of steroid-treated monkeys
27. Steroid regulation of estrogen and progestin receptor messenger ribonucleic acid in monkey hypothalamus and pituitary
28. Immunocytochemical localization of progestin receptors in monkey hypothalamus: Effect of estrogen and progestin
29. Effect of progesterone on prolactin, hypothalamic β-endorphin, hypothalamic substance P, and midbrain serotonin in guinea pigs
30. Pituitary and brain actions of estrogen and progesterone in the regulation of primate prolactin secretion
31. Search for progestin receptors in prolactin-releasing peptidergic neurons: Oxytocin neurons lack PR but respond to gonadal steroids
32. Steroid regulation of tryptophan hydroxylase protein in the dorsal raphe of macaques
33. Ovarian steroids and serotonin neural function
34. Differential expression of progestin receptor isoforms in the hypothalamus, pituitary, and endometrium or rhesus macaques
35. Serotonin receptor modulation by estrogen in discrete brain nuclei
36. Modulation by estradiol of serotonin receptors in brain
37. Serotonergic and noradrenergic receptors in the rat brain: Modulation by chronic exposure to ovarian hormones
38. Serotonin 5-HT (1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats
39. Modification of gonadectomy-induced increases in brain monoamine metabolism by steroid hormones in male and female rats
40. Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAa receptors
41. Sex difference in 5HT2 receptor in the living human brain
42. Biogenic amine transporters: Regulation in flux
43. Molecular physiology of norepinephrine and serotonin transporters
44. Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins
45. Pharmacology of rapid-onset antidepressant treatment strategies
46. Serotoninergic but not noradrenergic neurons in rat central nervous system adapt to long-term treatment with monoamine oxidase inhibitors
47. The effect of estrogen replacement therapy on plasma serotonin and catecholamines of postmenopausal women
48. Comparative effects of chronic 8-OH-DPAT, gepirone and ipsapirone treatment on the sensitivity of somatodendritic 5HT1A autoreceptors
49. Absence of 5-HT1B receptors is associated with impaired impulse control in male 5-HT1B knockout mice
50. Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine
51. Cyclic changes in the primate oviduct and endometrium
52. Hormonal regulation of the reproductive tract in female mammals
53. Cellular and molecular mechanisms of estrogen regulation of memory function and neuroprotection against Alzheimer's disease: Recent insights and remaining challenges
54. The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain
55. Behavioral and physiological consequences of repeated daily intracerebroventricular injection of corticotropin-releasing factor in the rat
56. A regional study of sex differences in rat brain serotonin
57. Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: Relationship to clinical improvement
58. The estrogen receptor regulates NFkappaB and AP-1 activity in a cell-specific manner
59. Comparative anatomical distribution of 5HT1A receptor mRNA and 5HT1A binding in rat brain - A combined in situ hybridization/in vitro receptor autoradiographic study
60. Serotonin transporter gene polymorphism and neurobehavioral development in rhesus monkey neonates
61. Human brain serotonin synthesis capacity measured in vivo with alpha-[c-11] methyl-L-tryptophan
62. Cell-specific regulation of progesterone receptor in the female reproductive system
63. Estrogen enhances a 5HT1A response in hippocampal slices from female rats
64. Estrogen effects on 5HT1A receptors in hippocampal membranes from ovariectomized rats: Functional and binding studies
65. 5-HT 2A/2C receptor blockade by amesergide fully attenuates prolactin response to d-fenfluramine challenge in physically healthy human subjects
66. Effects of estradiol on the diurnal rhythm of serotonin activity in microdissected brain areas of ovariectomized rats
67. Effects of ovarian steroids on serotonin metabolism within grossly dissected and microdissected brain regions of the ovariectomized rat
68. Sex differences in neuroanatomical and clinical correlations in schizophrenia
69. Psychopharmacology of 5-HT(1A) receptors
70. Gonadal hormones modulate 5-hydroxytryptamine 2A receptors: Emphasis on the rat frontal cortex
71. Electrophysiologically-identified serotonin receptors in the rat CNS. Effect of antidepressant treatment
72. Well being, symptoms and the menopausal transition
73. Estradiol down-regulates LPS-induced cytokine production and NF-κB activation in murine macrophages
74. Effect of acute and chronic 17β estradiol treatment on serotonin and 5-hydroxyindole acetic acid content of discrete brain nuclei of ovariectomized rat
75. Autoradiographic analysis of serotonin 5HT1A receptor binding in the human brain postmortem: Effects of age and alcohol
76. Tryptophan hydroxylase gene 218A/C polymorphism is associated with somatic anxiety in major depressive disorder
77. Differential control of tryptophan hydroxylase expression in raphe and in pineal gland: Evidence for a role of translation efficiency
78. Self-injurious behavior is decreased by cyproterone acetate in adult male rhesus (Macaca mulatta)
79. Heterogeneity of pig liver and pig brain mitochondrial monoamine oxidase
80. Mood response to acute tryptophan depletion in healthy volunteers: Sex differences and temporal stability
81. Human estrogen receptor β gene structure, chromosomal localization and expression pattern
82. Cerebrospinal fluid levels of monoamine metabolites. A preliminary study of their relation to menstrual cycle phase, sex steroids, and pituitary hormones in healthy women and in women with premenstrual syndrome
83. Microdialysis measurement of neurochemical changes in the mediobasal hypothalamus of ovariectomized ewes during oestrus
84. In vivo evidence for progesterone dependent decreases in serotonin release in the hypothalamus and midbrain central grey: Relation to the induction of lordosis
85. The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsy
86. 5-Hydroxytryptamine receptors
87. Insulin reduces norepinephrine transporter mRNA in vivo in rat locus ceruleus
88. Estrogen and mental state
89. Sex differences in serotonin 1 receptor binding in rat brain
90. Modified structure of the human serotonin transporter promoter
91. Intrahypothalamic 5,7-dihydroxytryptamine: Temporal analysis of effects on 5-hydroxytryptamine content in brain nuclei and on facilitated lordosis behavior
92. Demonstration of the phosphorylation-dependent interaction of tryptophan hydroxylase with the 14-3-3 protein
93. Search for association between suicide attempt and serotonergic mechanisms
94. Effect of progesterone on serotonin turnover in rats primed with estrogen implants into the ventromedial hypothalamus
95. The A and B isoforms of the human progesterone receptor: Two functionally different transcription factors encoded by a single gene
96. Psychiatric syndromes linked to reproductive function in women: A review of current knowledge
97. Onset of the receptive and proceptive components of feminine sexual behavior in rats following the intravenous administration of progesterone
98. How do antidepressants affect serotonin receptors? The role of serotonin receptors in the therapeutic and side effect profile of the SSRIs
99. The pharmacology of the behavioural and hypothermic responses of rats to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)
100. Estrogen receptor structure and function in breast cancer cells
101. Transdermal estrogen for treatment of severe postnatal depression
102. Progestin receptors: Isoforms and antihormone action
103. 3H]imipramine binding in the human brain postmortem: Effects of age and alcohol
104. The suicide brain - A review of postmortem receptor/transporter binding studies
105. 3H]desmethylimipramine binding in the human brain postmortem
106. Autoradiographic analysis of tritiated imipramine binding in the human brain post mortem: Effects of suicide
107. Distribution of estrogen receptor beta (ERβ) mRNA in hypothalamus, midbrain and temporal lobe of spayed macaque: Continued expression with hormone replacement
108. Ovarian steroid regulation of monoamine oxidase-A and -B mRNAs in the macaque dorsal raphe and hypothalamic nuclei
109. Estrogen receptor beta (ERβ) mRNA and protein in serotonin neurons of macaques
110. Ovarian steroid effects on serotonin 1A, 2A and 2C receptor mRNA in macaque hypothalamus
111. Differences in hypothalamic serotonin between estrous phases and gender: An in vivo microdialysis study
112. Epidemiology of schizophrenia
113. Estrogen augments serotonergic activity in postmenopausal women
114. Influence of age, sex and diurnal variability on imipramine receptor binding and serotonin uptake in platelets of normal subjects
115. Altered serotonergic activity in women with dysphoric premenstrual syndromes
116. Development of peptide antagonists that target estrogen receptor β-coactivator interactions
117. The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens
118. Functional promoter and polyadenylation site mapping of the human serotonin (5HT) transporter gene
119. Allelic variation of human serotonin transporter gene expression
120. Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons
121. Participation of serotonin in the phasic release of LH. I. Evidence from pharmacological experiments
122. Localization and dynamic regulation of biogenic amine transporters in the mammalian central nervous system
123. Distribution of 5HT1C receptor mRNA in adult rat brain
124. Tissue-specific effects of estrogen on monoamine oxidase A and B in the rat
125. Association between tryptophan hydroxylase gene polymorphism (A218C) and schizophrenic disorders
126. International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin)
127. 5-HT receptor classification and nomenclature: Toward a harmonization with the human genome
128. Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5HT1A recognition sites. Apparent absence of 5HT1B recognition sites
129. Hormone-neurotransmitter interactions in the control of sexual behavior
130. The tuberomammillary nucleus projections in the control of learning, memory and reinforcement processes: Evidence for an inhibitory role
131. The 14-3-3 protein binds its target proteins with a common site located toward the C-terminus
132. Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase
133. Changes in the serotonergic system during the sleep-wake cycle: Simultaneous polygraphic and voltammetric recordings in hypothalamus using a telemetry system
134. Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogen and xenoestrogens in MCF-7 cells
135. Distinct forms of the protein kinase-dependent activator of tyrosine and tryptophan hydroxylases
136. Association of a 5-HT(5A) rece1ptor polymorphism, Pro15Ser, to schizophrenia
137. Prior treatment with estrogen attenuates the effects of the 5-HT1A agonist, 8-OH-DPAT, on lordosis behavior
138. Structure and function of the brain serotonin system
139. Localization of monoamine oxidase A and B mRNA in the rat brain by in situ hybridization
140. Differential involvement of 5-hydroxy-tryptamine (5HT) in specific hypothalamic areas in the mediation of steroid-induced changes in gonadotropin release and sexual behavior in female rats
141. Tryptophan hydroxylase is phosphorylated by protein kinase A
142. Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A
143. Acute effects of estradiol on circulating luteinizing hormone and prolactin concentrations and on serotonin turnover in individual brain nuclei
144. Effects of acute and chronic phenelzine on regional monoamine metabolism in rats and its potentiation by deuterium substitution
145. Involvement of 5HT1, 5HT2 and 5HT3 receptors in mediation of the prolactin response to serotonin and 5-hydroxytryptophan
146. Effect of serotonin receptor agonists on prolactin secretion in male rats
147. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones
148. Hyperactivity of CRH neuronal circuits as a target for therapeutic interventions in affective disorders
149. Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways
150. Effect of ovarian steroids to stimulate region-specific hypothalamic 5-hydroxytryptamine synthesis in ovariectomized rats
151. Estrogen therapy for severe persistent depressions in women
152. Role of classic and peptide neuromediators in the neuroendocrine regulation of luteinizing hormone and prolactin
153. Differential regulation of serotonin (5-HT) release in the striatum and hippocampus by 5-HT1A autoreceptors of the dorsal and median raphe nuclei
154. Chronic administration of the 5-HT1A receptor agonist 8-OH-DPAT differentially desensitizes 5-HT1A autoreceptors of the dorsal and median raphe nuclei
155. Phosphorylation and activation of brain tryptophan hydroxylase: Identification of serine-58 as a substrate site for protein kinase A
156. Amino-terminal analysis of tryptophan hydroxylase: Protein kinase phosphorylation occurs at serine-58
157. Molecular cloning, functional expression and pharmacological characterization of a novel serotonin receptor (5-hydroxy-tryptamine 2F) from rat stomach fundus
158. Different serotonin receptor subtypes participate in 5-hydroxytryptophan-induced gonadotropins and prolactin release in the female infantile rat
159. Effect of progesterone on regional 5-hydroxytryptamine metabolism in the rat brain
160. Involvement of serotonergic pathways in mediating the neuronal activity and genetic transcription of neuroendocrine corticotropin-releasing factor in the brain of systemically endotoxin-challenged rats
161. Estrogen-induced modulation of serotonin 5HT1A mediated responses in the dorsal raphe nucleus (DRN)
162. Central 5-HT(1A) receptors: Regional distribution and functional characteristics
163. Differences in ketanserin binding in the ventromedial hypothalamus of ewes responsive or refractory to short days
164. Effects of the menstrual cycle on dependent variables in mood disorder research
165. The role of serotonin in eating disorders
166. Transmitter content and afferent connections of estrogen-sensitive progestin receptor-containing neurons in the primate hypothalamus
167. Estrogen responsive cells in the arcuate nucleus of the rat contain glutamic acid decarboxylase (GAD): An electron microscopic immunocytochemical study
168. High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells
169. Gender, estrogen, and schizophrenia
170. Gender-related clinical differences in older patients with schizophrenia
171. Serotonin metabolite excretion after postmenopausal estradiol therapy
172. Sex difference in age at onset of schizophrenia
173. New mouse 5HT-2 like receptor. Expression in brain, heart, and intestine
174. Extracellular serotonin in the lateral hypothalamic area is increased during the postejaculatory interval and impairs copulation in male rats
175. A novel adenylyl cyclase-activating serotonin receptor (5HT7) implicated in the regulation of mammalian circadian rhythms
176. Ovarian steroid regulation of 5HT1A receptor binding and G protein activation in female monkeys
177. Ovarian steroid action on tryptophan hydroxylase protein and serotonin compared to localization of ovarian steroid receptors in guinea pigs
178. Effects of monoamine oxidase inhibition on female sexual behavior, serotonin levels and type A and B monoamine oxidase activity
179. Gonadal hormone regulation of MAO and other enzymes in hypothalamic areas
180. Detection of MAO-A and MAO-B mRNAs in monkey brainstem by cross-hybridization with human oligonucleotide probes
181. Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families
182. Neurosteroids: Endogenous bimodal modulators of the GABA-A receptor. Mechanism of action and physiological significance
183. 123I]-2beta-carbomethoxy-3beta-(4-iodophenyl)tropane and single photon emission computed tomography
184. Family-based association study of the serotonin transporter promoter region polymorphism (5-HTTLPR) in attention deficit hyperactivity disorder
185. Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel
186. Protective actions of the 5-HT2A/2C receptor agonist, DOI, on 5-HT1A receptor-mediated inhibition of lordosis behavior
187. Cross-talk between nuclear factor-kB and the steroid hormone receptors: Mechanisms of mutual antagonism
188. Molecular control of immune/inflammatory responses: Interactions between nuclear factor-κB and steroid receptor-signaling pathways
189. Chronic administration of the antidepressant-antipanic drug phenelzine and its N-acetylated analogue: Effects on monoamine oxidase, biogenic amines and alpha 2-adrenoreceptor function
190. Oestradiol-17β increases serotonin transporter (SERT) binding sites and SERT mRNA expression in discrete regions of female rat brain
191. Estradiol-17β increases serotonin transporter (SERT) mRNA levels and the density of SERT-binding sites in female rat brain
192. 3H]-paroxetine binding in the cerebral cortex and dorsal hippocampus of gonadectomized male and female rats
193. Involvement of a putative protein-tryrosine phosphatase and I kappa B-alpha serine phosphorylation in nuclear factor kappa B activation by tumor necrosis factor
194. Uptake of serotonin and norepinephrine in hypothalamic and limbic brain regions during the estrous cycle and the effect of neurotoxic lesions on estrous cyclicity
195. Oestrogen, progesterone and serotonin converge on GABAergic neurones in the monkey hypothalamus
196. Dopaminergic and serotonergic activity in the hypothalamus during early and late pregnancy
197. The role of corticotropin releasing factor in depressive illness: A critical review
198. Serotonin oxidation by type B MAO of rat brain
199. Characterization of a novel ERβ antibody and localization of ERβ immunoreactivity in mouse brain
200. 17β-Estradiol rapidly decreases 5-HT1A receptor function in rat hippocampus in vitro: Role of PKA and PKC
201. 35S]GTPgammaS binding
202. Estrogens act in rat hippocampus and frontal cortex to produce rapid, receptor-mediated decreases in serotonin 5HT(1A) receptor function
203. 5HT1C receptor is a prominent serotonin receptor subtype in the central nervous system
204. A continuous fluorescence assay for tryptophan hydroxylase
205. A physiological dose of estradiol with progesterone affects striatum biogenic amines
206. Hormone replacement therapy is associated with widespread increases in 5HT2A receptor binding potential in the cerebral cortex of euthymic postmenopausal women
207. The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder: Preliminary findings
208. Suicide, impulsive aggression, and HTR1B genotype
209. Interaction of short-range repressors with Drosophila CtBP in the embryo
210. A tryptophan hydroxylase gene marker for suicidality and alcoholism
211. Estrogen receptor transcription and transactivation: Basic aspects of estrogen action
212. Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients
213. Differences between males and females in rates of serotonin synthesis in human brain
214. Sex differences in brain morphology in schizophrenia
215. Prolactin and cortisol responses to d-fenfluramine in major depression: Evidence for diminished responsivity of central serotonergic function
216. d-Fenfluramine/prolactin response throughout the menstrual cycle: Evidence for an estrogen-induced alteration
217. Maternal behavior in rats with kainic acid-induced lesions of the hypothalamic paraventricular nucleus
218. Estrogen in the treatment of depression: Neuropharmacological mechanisms
219. Hypothalamic monoamine oxidase activity in ovariectomized rats after sexual behavior restoration
220. Effects of chronic 17β-estradiol treatment on the serotonin 5-HT1A receptor mRNA and binding levels in the rat brain
221. Acute 17β-estradiol treatment down-regulates serotonin 5HT1A receptor mRNA expression in the limbic system of female rats
222. The Flinders sensitive line rats, a genetic model of depression, show abnormal serotonin receptor mRNA expression in the brain that is reversed by 17beta-estradiol
223. Raised levels of plasma interleukin-1beta in major and postviral depression
224. Serotonin and sexual behavior in the male rabbit
225. Serotonergic terminals in the anterior hypothalamic nucleus involved in prolactin release during suckling
226. Increased anxiety of mice lacking the serotonin 1A receptor
227. High affinity binding of antidepressants to biogenic amine transport sites in human brain and platelet: Studies in depression
228. Serotonin receptors in the human brain. III. Autoradiographic mapping of serotonin-1 receptors
229. Hormones and depression: What are the facts about premenstrual syndrome, menopause and hormone replacement therapy?
230. Ovarian steroid regulation of 5HT1A autoreceptor messenger ribonucleic acid expression in the dorsal raphe of rhesus macaques
231. Regulation of serotonin re-uptake transporter mRNA expression by ovarian steroids in rhesus macaques
232. Ovarian steroid regulation of tryptophan hydroxylase mRNA expression in rhesus macaques
233. Molecular biology of serotonin (5HT) receptors
234. The role of hormones in depression
235. Association between bipolar disorder and monoamine oxidase A gene polymorphisms: Results of a multicenter study
236. Impulsive traits and 5-HT2A receptor polymorphism in alcohol dependents: Possible association but no influence of personality disorders
237. Estrogen desensitizes 5HT(1A) receptors and reduces levels of G(z), G(i1) and G(i3) proteins in the hypothalamus
238. Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
239. Phosphorylation and regulation of antidepressant-sensitive serotonin transporters
240. The recombinant 5-HT1A receptor: G protein coupling and signaling pathways
241. Upregulation of imipramine binding and serotonin uptake by estradiol in female rat brain
242. Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine
243. Monoamine levels and turnover in brain: Relationship to priming actions of estrogen
244. Analysis of temporal and dose-dependent effects of estrogen on monoamines in brain nuclei
245. 3H]nitroimipramine binding in brain nuclei
246. Effect of progesterone on monoamine turnover in the brain of the estrogen-primed rat
247. Molecular neuroanatomy of monoamine oxidases in human brainstem
248. Tryptophan depletion in normal volunteers produces selective impairment in memory consolidation
249. Reorganization of ascending 5HT axon projections in animals previously exposed to the recreational drug (±)3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy")
250. Neurons in the hypothalamic paraventricular nucleus mediate the serotonin stimulus of prolactin secretion via 5HT1C/2 receptors
251. Imipramine receptor binding and serotonin uptake in platelets of women with premenstrual changes
252. Identification of four variants in the tryptophan hydroxylase promoter and association to behavior
253. Estrogen-serotonin interactions: Implications for affective regulation
254. Estradiol modulation of the hyperphagia induced by the 5-HT1A agonist, 8-OH-DPAT
255. A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform
256. Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry
257. 3H]-Ro 19-6327 in vitro: Localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain
258. The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat
259. Temporally distinct and ligand-specific recruitment of nuclear receptor-interacting peptides and cofactors to subnuclear domains containing the estrogen receptor
260. Neuroregulatory role of gonadal steroids in humans
261. Estrogen replacement in perimenopause-related depression: A preliminary report
262. Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome
263. Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial
264. Induction of corticotropin-releasing hormone gene expression by glucocorticoids: Implication for understanding the states of fear and anxiety and allostatic load
265. Effect of estrogen (E) and progesterone (P) on CSF concentrations of biogenic amines in pigtail macaques
266. The distribution of cells containing estrogen receptor-alpha (ERalpha) and ERbeta messenger ribonucleic acid in the preoptic area and hypothalamus of the sheep: Comparison of males and females
267. Psychopathology in women and men: Focus on female hormones
268. Association between the serotonin 2C receptor gene and tardive dyskinesia in chronic schizophrenia: Additive contribution of 5-HT2Cser and DRD3gly alleles to susceptibility
269. Effect of acute and repeated administration of 5HT1A receptor agonists on 5HT release in rat brain in vivo
270. Menopause, early aging and elderly women
271. Estrogen and cognitive function throughout the female lifespan
272. 3H]-imipramine binding sites in surgically menopausal women
273. Effects of castration, estrogen replacement and estrus cycle on monoamine metabolism in the nucleus accumbens measured by microdialysis
274. The distribution of estrogen receptor-β mRNA in the rat hypothalamus
275. Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
276. Biologically active estrogen receptor-β: Evidence from in vivo autoradiographic studies with estrogen receptor α-knockout mice
277. II. Critical issues in defining the role of serotonin in psychiatric disorders
278. Region-specific changes in 5-HT(1A) receptor-activated G-proteins in rat brain following chronic buspirone
279. Distribution and regulation of steroid hormone receptor gene expression in the central nervous system
280. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study
281. Effects of estradiol benzoate on 5HT1A receptor mRNA in the mediobasal hypothalamus of female rats
282. Serotonin outflow in the hypothalamus of conscious rats: Origin and possible involvement in cardiovascular control
283. Antidepressant-like activity of compounds with varying efficacy at 5HT1A receptors
284. Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
285. Regulation and localization of estrogen and progestin receptors in the pituitary of steroid treated monkeys
286. (-)-Propanolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5HT1A selective agonists
287. Postpartum psychiatric disorders
288. Premenstrual dysphoria and the serotonin system: Pathophysiology and treatment
289. Psychologic distress during menopause: Associations across the reproductive life cycle
290. Expression of estrogen receptor-alpha and -beta immunoreactivity in the cultured neonatal suprachiasmatic nucleus: With special attention to GABAergic neurons
291. Effect of menstrual cycle phase on neuroendocrine and behavioral responses to the serotonin agonist m-chlorophenylpiperazine in women with premenstrual syndrome and controls
292. Effects of acute estradiol on 5-hydroxytryptamine and dopamine receptor subtype mRNA expression in female rat brain
293. Estrogen increases the density of 5-hydroxytryptamine 2A receptors in the cerebral cortex and nucleus accumbens in the female rat
294. The density of 5-hydroxytryptamine 2A receptors in forebrain is increased at pro-oestrus in intact female rats
295. Estrogen inhibits phorbol ester-induced I kappa B alpha transcription and protein degradation
296. Memory and the region of the mammillary bodies
297. Susceptibility to neuroleptic induced tardive dyskinesia and the T102C polymorphism in the serotonin type 2A receptor
298. Evidence for 5HT2 receptor involvement in the stimulation of preovulatory LH and prolactin release and ovulation in normal cycling rats
299. Lack of effects of 5-HT3 antagonists on normal and morphine-attenuated sexual behaviors in female and male rats
300. Effects of 5-HT3 agonists on reproductive behaviors in rats
301. The neuroactive steroid 5alpha-tetrahydrodeoxycorticosterone increases GABAergic postsynaptic inhibition of rat neocortical neurons in vitro
302. Specificities of the two forms of monoamine oxidase
303. Role of the serotonin transporter gene in the behavioral expression of autism
304. Reduced efficacy of 8-OH-DPAT's inhibition of lordosis behavior by prior estrogen treatment
305. Molecular mechanisms of action of steroid/thyroid receptor superfamily members
306. Association analysis of the 5-HT6 receptor polymorphism C267T in Alzheimer's disease
307. Immunocytochemical localization of midbrain estrogen receptor-and progestin receptor-containing cells in female guinea pigs
308. Steroid regulation of progesterone receptor expression in cultured rat gonadotropes
309. Progesterone regulation of the progesterone receptor in rat gonadotropes
310. Serotoninergic control of gonadotropin and prolactin secretion in women
311. Multiple serotonin receptors: Too many, not enough, or just the right number?
312. Effects of mianserin and ketanserin on lordosis behavior after systemic treatment or infusion into the ventromedial nucleus of the hypothalamus
313. Regional distribution of glutamic acid decarboxylase (GAD65 and GAD67) mRNA in the hypothalamus of male rhesus macaques before and after puberty
314. Prolactin response to d-fenfluramine in postmenopausal women on and off ERT: Comparison with young women
315. Neuroendocrine pharmacology of serotonergic (5HT) neurons
316. Pharmacological evidence that serotonergic stimulation of prolactin secretion is mediated via the dorsal raphe nucleus
317. Serotonergic stimulation of prolactin and corticosterone secretion is mediated by different pathways from the mediobasal hypothalamus
318. Serotonergic regulation of renin and prolactin secretion
319. Neuropathology of bipolar disorder
320. Low brain serotonin turnover rate (low CSF 5-HIAA) and impulsive violence
321. Investigation of the human serotonin 6 [5-HT6] receptor gene in bipolar affective disorder and schizophrenia
322. Changes in hypothalamic serotonin associated with amplification of LH surges by progesterone in rats
323. Depression and anxiety: Role of the locus coeruleus and corticotropin releasing factor
324. Gender and depression
325. Depression in women: Implications for health care research
326. Distinct monoamine oxidase A and B populations in primate brain
327. Localization of distinct monoamine oxidase A and monoamine oxidase B cell populations in human brainstem
328. Comparative analyses of mechanistic differences among antiestrogens
329. Gender differences in depression in primary care
330. Hyperprolactinemia in monkeys: Induction by an estrogen-progesterone synergy
331. Hyperprolactinemia induced by an estrogen-progesterone synergy: Quantitative and temporal effects of estrogen priming in monkeys
332. Origin of serotonin innervation of the arcuate and ventromedial hypothalamic region
333. The effect of oestradiol dipropionate and progesterone on monoamine uptake in rat brain
334. Regulation of the rat serotonin-1A receptor gene by corticosteroids
335. A dual mechanism mediates repression of NF-κB activity by glucocorticoids
336. The serotonin 5-HT2C receptor is a prominent serotonin receptor in basal ganglia: Evidence from functional studies on serotonin-mediated phosphoinositide hydrolysis
337. Comparative localization of serotonin 1A, 1C and 2 receptor subtype mRNA in rat brain
338. Is 5HT1A receptor subsensitivity a trait marker for late luteal phase dysphoric disorder? A pilot study
339. Significance of serotonin transporter gene polymorphism in migraine
340. New directions in monoamine oxidase A and B selective inhibitors and substrates
341. On the significance of subterritories in the "accumbens" part of the rat ventral striatum
342. A nuclear receptor corepressor modulates transcriptional activity of antagonist-occupied steroid hormone receptor
343. 5-HTTLPR variants not associated with autistic spectrum disorders