메뉴 건너뛰기




Volumn 127, Issue 8, 1999, Pages 1751-1764

The recombinant 5-HT(1A) receptor: G protein coupling and signalling pathways

Author keywords

5 Hydroxytryptamine; Adenylyl cyclase; Calcium; Efficacy; G protein; Phospholipase; Potency; Transfection

Indexed keywords

ADENYLATE CYCLASE; COMPLEMENTARY DNA; GUANINE NUCLEOTIDE BINDING PROTEIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PHOSPHOLIPASE; RECOMBINANT RECEPTOR; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR;

EID: 0032588147     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702723     Document Type: Review
Times cited : (218)

References (155)
  • 1
    • 0026643693 scopus 로고
    • Conditional transformation mediated via a pertussis toxin-sensitive receptor signalling pathway
    • Abdel-Baset, H., Bozovick, V., Szyf, M. & Albert, P.R. (1992). Conditional transformation mediated via a pertussis toxin-sensitive receptor signalling pathway. Mol. Endo., 6, 730-740.
    • (1992) Mol. Endo. , vol.6 , pp. 730-740
    • Abdel-Baset, H.1    Bozovick, V.2    Szyf, M.3    Albert, P.R.4
  • 2
    • 0031589608 scopus 로고    scopus 로고
    • 1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo
    • 1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo. Brain Res., 777, 179-186.
    • (1997) Brain Res. , vol.777 , pp. 179-186
    • Ahleymeyer, B.1    Krieglstein, J.2
  • 6
    • 0028997231 scopus 로고
    • Hyperammonemia increases serotonin 1A receptor expression in both rat hippocampus and a transfected hippocampal cell line, HN2-5
    • Alexander, J.J., Banerjee, P., Dawson, G. & Tonsgard, J.H. (1995). Hyperammonemia increases serotonin 1A receptor expression in both rat hippocampus and a transfected hippocampal cell line, HN2-5. J. Neurosci. Res., 41, 105-110.
    • (1995) J. Neurosci. Res. , vol.41 , pp. 105-110
    • Alexander, J.J.1    Banerjee, P.2    Dawson, G.3    Tonsgard, J.H.4
  • 7
    • 0030611748 scopus 로고    scopus 로고
    • Role of phospholipase Cb3 phosphorylation in the desensitization of cellular responses to platelet-activating factor
    • Ali, H., Fisher, I., Haribabu, B., Richardson, R.M. & Snyderman, R. (1997). Role of phospholipase Cb3 phosphorylation in the desensitization of cellular responses to platelet-activating factor. J. Biol. Chem., 272, 11706-11709.
    • (1997) J. Biol. Chem. , vol.272 , pp. 11706-11709
    • Ali, H.1    Fisher, I.2    Haribabu, B.3    Richardson, R.M.4    Snyderman, R.5
  • 8
    • 0023470549 scopus 로고
    • Pharmacological distribution of serotonin receptors on single pyramidal neurones of the rat hippocampus recorded in vitro
    • Andrade, R. & Nicoll, R.A. (1986). Pharmacological distribution of serotonin receptors on single pyramidal neurones of the rat hippocampus recorded in vitro. J. Physiol., 394, 99-124.
    • (1986) J. Physiol. , vol.394 , pp. 99-124
    • Andrade, R.1    Nicoll, R.A.2
  • 10
    • 0030609085 scopus 로고    scopus 로고
    • 1A receptor agonist properties of the antipsychotic, nemonapride: Comparison with bromerguride and colzapine
    • 1A receptor agonist properties of the antipsychotic, nemonapride: comparison with bromerguride and colzapine. Eur. J. Pharmacol., 334, 141-147.
    • (1997) Eur. J. Pharmacol. , vol.334 , pp. 141-147
    • Assie, M.B.1    Cosi, C.2    Kofk, W.3
  • 11
    • 0028238911 scopus 로고
    • Inhibitors of serotonin synthesis and antagonists of serotonin 1A receptors inhibit T lymphocyte function in vitro and cell-mediated immunity in vivo
    • Aune, T.M., Golden, H.W. & McGrath, K.M. (1994). Inhibitors of serotonin synthesis and antagonists of serotonin 1A receptors inhibit T lymphocyte function in vitro and cell-mediated immunity in vivo. J. Immunol., 153, 489-498.
    • (1994) J. Immunol. , vol.153 , pp. 489-498
    • Aune, T.M.1    Golden, H.W.2    McGrath, K.M.3
  • 12
    • 0027326833 scopus 로고
    • Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytrayptamine
    • Aune, T.M., McGrath, K.M., Sarr, T., Bombara, M.P. & Kelley, K.A. (1993). Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytrayptamine. J. Immunol., 151, 1175-1183.
    • (1993) J. Immunol. , vol.151 , pp. 1175-1183
    • Aune, T.M.1    McGrath, K.M.2    Sarr, T.3    Bombara, M.P.4    Kelley, K.A.5
  • 13
    • 0032427637 scopus 로고    scopus 로고
    • Holtzman and Sprague-Dawley rats: Differences in DRL-72-sec performance and 8-hydroxy-di-propylamino teralin-induced hypothermia
    • Balcells-Olivero, M., Cousins, M.S. & Seiden, L.S. (1998). Holtzman and Sprague-Dawley rats: differences in DRL-72-sec performance and 8-hydroxy-di-propylamino teralin-induced hypothermia. J. Pharmacol. Expt. Ther., 286, 742-752.
    • (1998) J. Pharmacol. Expt. Ther. , vol.286 , pp. 742-752
    • Balcells-Olivero, M.1    Cousins, M.S.2    Seiden, L.S.3
  • 15
    • 0031029553 scopus 로고    scopus 로고
    • Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor: G protein coupling
    • Barr, A.J., Brass, L.F. & Manning, D.R. (1997). Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor: G protein coupling. J. Biol. Chem., 272, 2223-2229.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2223-2229
    • Barr, A.J.1    Brass, L.F.2    Manning, D.R.3
  • 16
    • 0031468622 scopus 로고    scopus 로고
    • 1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists
    • 1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists. J. Biol. Chem., 272, 32979-32987.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32979-32987
    • Barr, A.J.1    Manning, D.R.2
  • 17
    • 0027332498 scopus 로고
    • The Iκβ proteins: Multifunctional regulators of rel/NFκ-B transcription
    • Berg, A.A. & Baldwin, A.S. (1993). The Iκβ proteins: multifunctional regulators of rel/NFκ-B transcription. Genes Dev., 7, 2064-2070.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Berg, A.A.1    Baldwin, A.S.2
  • 18
    • 0032531818 scopus 로고    scopus 로고
    • Calcium A life and death signal
    • Berridge, M.J., Bootman, M.D. & Lipp, P. (1998). Calcium A life and death signal. Nature, 395, 645-658.
    • (1998) Nature , vol.395 , pp. 645-658
    • Berridge, M.J.1    Bootman, M.D.2    Lipp, P.3
  • 20
    • 0021826466 scopus 로고
    • Pharmacological analysis of beta-adrenoceptor-mediated agonism in the guinea-pig, isolated, right atrium
    • Black, J.W., Leff, P. & Shankley, N.P. (1985). Pharmacological analysis of beta-adrenoceptor-mediated agonism in the guinea-pig, isolated, right atrium. Br. J. Pharmacol., 84, 561-571.
    • (1985) Br. J. Pharmacol. , vol.84 , pp. 561-571
    • Black, J.W.1    Leff, P.2    Shankley, N.P.3
  • 25
    • 0028819880 scopus 로고
    • Binding properties of the naturally occurring human 5-HT1A receptor variant with the Ile28Val substitution in the extracellular domain
    • Hrüss, M., Hühlen, M., Erdmann, J., Göthert, M. & Bönisch, H. (1995). Binding properties of the naturally occurring human 5-HT1A receptor variant with the Ile28Val substitution in the extracellular domain. Naunyn-Schmied. Arch. Pharmacol., 352, 455-458.
    • (1995) Naunyn-Schmied. Arch. Pharmacol. , vol.352 , pp. 455-458
    • Hrüss, M.1    Hühlen, M.2    Erdmann, J.3    Göthert, M.4    Bönisch, H.5
  • 28
    • 0026457062 scopus 로고
    • Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction
    • Cai, H., Erhardt, P., Szeberenyi, J., Diaz-Meco, M.T., Johansen, T., Moscat, J. & Cooper, G.M. (1992). Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction. Mol Cell Biol., 12, 5329-5335.
    • (1992) Mol Cell Biol. , vol.12 , pp. 5329-5335
    • Cai, H.1    Erhardt, P.2    Szeberenyi, J.3    Diaz-Meco, M.T.4    Johansen, T.5    Moscat, J.6    Cooper, G.M.7
  • 29
    • 0027488642 scopus 로고
    • Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction
    • Cai, H., Erhardt, P., Troppmair, J., Diaz-Meco, Sithanandam, G., Rapp, U.R., M.T., Moscat, J. & Cooper, G.M. (1993). Hydrolysis of phosphatidylcholine couples Ras to activation of Raf protein kinase during mitogenic signal transduction. Mol. Cell Biol., 13, 7645-7651.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 7645-7651
    • Cai, H.1    Erhardt, P.2    Troppmair, J.3    Diaz-Meco, M.T.4    Sithanandam, G.5    Rapp, U.R.6    Moscat, J.7    Cooper, G.M.8
  • 33
    • 0027133073 scopus 로고
    • Cloning and differentiation-induced expression of a murine serotonin 1A receptor in a septal cell line
    • Charest, A., Wainer, B.H. & Albert, P.R. (1993). Cloning and differentiation-induced expression of a murine serotonin 1A receptor in a septal cell line. J. Neurosci., 13, 914-923.
    • (1993) J. Neurosci. , vol.13 , pp. 914-923
    • Charest, A.1    Wainer, B.H.2    Albert, P.R.3
  • 34
    • 0023819616 scopus 로고
    • 1A receptor agonists inhibit carbachol-induced stimulation of phosphoinositide turnover in rat hippocampus
    • 1A receptor agonists inhibit carbachol-induced stimulation of phosphoinositide turnover in rat hippocampus. Eur. J. Pharmacol., 149, 149-153.
    • (1988) Eur. J. Pharmacol. , vol.149 , pp. 149-153
    • Claustre, Y.1    Benavides, J.2    Scatton, B.3
  • 35
    • 0030612004 scopus 로고    scopus 로고
    • 1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells
    • 1 receptor subtypes exhibit distinct G protein coupling behaviors in membranes from Sf9 cells. Biochemistry, 36, 12930-12938.
    • (1997) Biochemistry , vol.36 , pp. 12930-12938
    • Clawges, H.M.1    Depree, K.M.2    Parker, E.M.3    Graber, S.G.4
  • 36
    • 0023250760 scopus 로고
    • Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin
    • Colino, A. & Halliwell, J.V. (1987). Differential modulation of three separate K-conductances in hippocampal CA1 neurons by serotonin. Nature, 328, 73-77.
    • (1987) Nature , vol.328 , pp. 73-77
    • Colino, A.1    Halliwell, J.V.2
  • 37
    • 0030611419 scopus 로고    scopus 로고
    • 1A receptor-mediated increases in receptor expression and activation of NF-KB in transfected Chinese hamster ovary cells
    • 1A receptor-mediated increases in receptor expression and activation of NF-KB in transfected Chinese hamster ovary cells. Mol. Pharmacol., 42, 221-226.
    • (1997) Mol. Pharmacol. , vol.42 , pp. 221-226
    • Cowen, D.S.1    Molinoff, P.B.2    Manning, D.R.3
  • 38
    • 0029833766 scopus 로고    scopus 로고
    • 1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis
    • 1A receptor is sensitive not only to inhibitors of phosphatidylinositol 3-kinase, but to an inhibitor of phosphatidylcholine hydrolysis. J. Biol. Chem., 271, 22297-22300.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22297-22300
    • Cowen, D.S.1    Sowers, R.S.2    Manning, D.R.3
  • 42
    • 0022555590 scopus 로고
    • 1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes
    • 1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes. J. Pharmacol. Exp. Ther., 238, 248-253.
    • (1986) J. Pharmacol. Exp. Ther. , vol.238 , pp. 248-253
    • De Vivo, M.1    Maayani, S.2
  • 46
    • 0022259724 scopus 로고
    • Bidirectional control of cytosolic free calcium by thyrotropin-releasing hormone in pituitary cells
    • Drummond, A.H. (1985). Bidirectional control of cytosolic free calcium by thyrotropin-releasing hormone in pituitary cells. Nature, 315, 752-755.
    • (1985) Nature , vol.315 , pp. 752-755
    • Drummond, A.H.1
  • 47
    • 0032217303 scopus 로고    scopus 로고
    • Characterization of 5-HT1A receptor functional coupling in cells expressing the human 5-HT1A receptor as assessed with the cytosensor microphysiometer
    • Dunlop, J., Zhang, Y., Smith, D.L. & Schechter, L.E. (1998). Characterization of 5-HT1A receptor functional coupling in cells expressing the human 5-HT1A receptor as assessed with the cytosensor microphysiometer. J. Pharmacol. Toxicol. Methods, 40, 47-55.
    • (1998) J. Pharmacol. Toxicol. Methods , vol.40 , pp. 47-55
    • Dunlop, J.1    Zhang, Y.2    Smith, D.L.3    Schechter, L.E.4
  • 48
    • 0032557242 scopus 로고    scopus 로고
    • 5-HT1A receptor-mediated inhibition of long-term potentiation in rat visual cortex
    • Edagawa, Y., Saito, H. & Abe, K. (1998). 5-HT1A receptor-mediated inhibition of long-term potentiation in rat visual cortex. Eur. J. Pharmacol., 349, 221-224.
    • (1998) Eur. J. Pharmacol. , vol.349 , pp. 221-224
    • Edagawa, Y.1    Saito, H.2    Abe, K.3
  • 54
    • 0029921297 scopus 로고    scopus 로고
    • The human 5-hydroxytryptamine 1A receptor differentially modulates phospholipase C and adenylyl cyclase activities
    • Fenrick, R., Pou, C., Beliveau, M. & Fargin, A. (1996). The human 5-hydroxytryptamine 1A receptor differentially modulates phospholipase C and adenylyl cyclase activities. Gen. Pharmacol., 27, 263-268.
    • (1996) Gen. Pharmacol. , vol.27 , pp. 263-268
    • Fenrick, R.1    Pou, C.2    Beliveau, M.3    Fargin, A.4
  • 56
    • 0024382126 scopus 로고
    • Site-directed mutagenesis of β-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation
    • Fraser, C.M. (1989). Site-directed mutagenesis of β-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation. J. Biol. Chem., 264, 9266-9270.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9266-9270
    • Fraser, C.M.1
  • 72
    • 0033583237 scopus 로고    scopus 로고
    • Structure, mechanism, and regulation of mammalian adenylyl cyclase
    • Hurley, J.H., (1999). Structure, mechanism, and regulation of mammalian adenylyl cyclase. J. Biol. Chem., 274, 7599-7602.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7599-7602
    • Hurley, J.H.1
  • 74
    • 0026569389 scopus 로고
    • Receptor-mediated autocrine growth-stimulatory effect of 5-hydroxytryptamine on cultured human pancreatic carcinoid cells
    • Ishizuka, J., Beauchamp, R.D., Townsend, C.M., Greeley, G.H. & Thompson, J.C. (1992). Receptor-mediated autocrine growth-stimulatory effect of 5-hydroxytryptamine on cultured human pancreatic carcinoid cells. J. Cell. Physiol., 150, 1-7.
    • (1992) J. Cell. Physiol. , vol.150 , pp. 1-7
    • Ishizuka, J.1    Beauchamp, R.D.2    Townsend, C.M.3    Greeley, G.H.4    Thompson, J.C.5
  • 76
    • 0031694622 scopus 로고    scopus 로고
    • Novel mutations in the promoter and coding region of the human 5-HT1A receptor gene and association analysis in schizophrenia
    • Kawanishi, Y., Harada, S., Tachikawa, H., Okubo, T. & Shiraishi, H. (1998). Novel mutations in the promoter and coding region of the human 5-HT1A receptor gene and association analysis in schizophrenia. Am. J. Med. Genetics., 81, 434-439.
    • (1998) Am. J. Med. Genetics. , vol.81 , pp. 434-439
    • Kawanishi, Y.1    Harada, S.2    Tachikawa, H.3    Okubo, T.4    Shiraishi, H.5
  • 77
    • 0024600440 scopus 로고
    • Theoretical effects of single and multiple transducer receptor coupling proteins on estimates of the relative potency of agonists
    • Kenakin, T.P. & Morgan, P.H. (1988). Theoretical effects of single and multiple transducer receptor coupling proteins on estimates of the relative potency of agonists. Mol. Pharmacol., 35, 214-222.
    • (1988) Mol. Pharmacol. , vol.35 , pp. 214-222
    • Kenakin, T.P.1    Morgan, P.H.2
  • 78
    • 0023643263 scopus 로고
    • An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
    • Kobilka, B.K., Freille, T., Collins, S., Yang-Feng, T., Kobilka, T.S., Francke, U., Lefkowitz, R.J. & Caron, M.G. (1987). An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. Nature, 329, 75-79.
    • (1987) Nature , vol.329 , pp. 75-79
    • Kobilka, B.K.1    Freille, T.2    Collins, S.3    Yang-Feng, T.4    Kobilka, T.S.5    Francke, U.6    Lefkowitz, R.J.7    Caron, M.G.8
  • 84
    • 0027300281 scopus 로고
    • Neurotransmitters as growth regulatory signals: Roles of receptors and second messengers
    • Lauder, J.M. (1993). Neurotransmitters as growth regulatory signals: roles of receptors and second messengers. Trends Pharmacol. Sci., 16, 233-239.
    • (1993) Trends Pharmacol. Sci. , vol.16 , pp. 233-239
    • Lauder, J.M.1
  • 88
    • 0026329391 scopus 로고
    • 1A receptor. Modulation by protein kinases C and A
    • 1A receptor. Modulation by protein kinases C and A. J. Biol. Chem., 266, 23689-23697.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23689-23697
    • Liu, Y.F.1    Albert, P.R.2
  • 90
    • 0023728920 scopus 로고
    • Receptors linked to inhibition of adenylate cyclase: Additional signaling mechanisms
    • Limbird, L.E. (1988). Receptors linked to inhibition of adenylate cyclase: additional signaling mechanisms. FASEB J., 2, 2686-2695.
    • (1988) Faseb J. , vol.2 , pp. 2686-2695
    • Limbird, L.E.1
  • 93
    • 0030919094 scopus 로고    scopus 로고
    • Cloning and developmental expression of 5-HT1A receptor gene in Xenopus Iaevis
    • Marracci, S., Cini, D. & Nardi, I. (1997). Cloning and developmental expression of 5-HT1A receptor gene in Xenopus Iaevis. Brain Mol. Brain. Res., 47, 67-77.
    • (1997) Brain Mol. Brain. Res. , vol.47 , pp. 67-77
    • Marracci, S.1    Cini, D.2    Nardi, I.3
  • 94
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall, C.J. (1995). Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 80, 179-185.
    • (1995) Cell. , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 95
    • 0344222217 scopus 로고    scopus 로고
    • Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior
    • Maswood, N., Caldarola-Pastuszka, M. & Uphouse, L. (1998). Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior. Brain Res., 802, 98-103.
    • (1998) Brain Res. , vol.802 , pp. 98-103
    • Maswood, N.1    Caldarola-Pastuszka, M.2    Uphouse, L.3
  • 97
    • 0028986883 scopus 로고
    • High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells
    • Messier, T.L., Dorman, C.M., Brauner-Osborne, H., Eubanks, D. & Brann, M.R. (1995). High throughput assays of cloned adrenergic, muscarinic, neurokinin, and neurotrophin receptors in living mammalian cells. Pharmacol. Toxicol., 76, 308-311.
    • (1995) Pharmacol. Toxicol. , vol.76 , pp. 308-311
    • Messier, T.L.1    Dorman, C.M.2    Brauner-Osborne, H.3    Eubanks, D.4    Brann, M.R.5
  • 98
    • 0031712984 scopus 로고    scopus 로고
    • Alcohol-heightened aggression in mice: Attenuation by 5-HT1A receptor agonists
    • Miczek, K.A., Hussain, S. & Faccidomo, S. (1998), Alcohol-heightened aggression in mice: attenuation by 5-HT1A receptor agonists. Psychopharmacology, 139, 160-168.
    • (1998) Psychopharmacology , vol.139 , pp. 160-168
    • Miczek, K.A.1    Hussain, S.2    Faccidomo, S.3
  • 100
    • 0032189543 scopus 로고    scopus 로고
    • Regulation by serotonin of tooth-germ morphogenesis and gene expression in mouse mandibular explant cultures
    • Moisewitsch, J.R., Raymond, J.R., Tamir, H. & Lauder, J.M. (1998). Regulation by serotonin of tooth-germ morphogenesis and gene expression in mouse mandibular explant cultures. Arch. Oral Biol., 43, 789-800.
    • (1998) Arch. Oral Biol. , vol.43 , pp. 789-800
    • Moisewitsch, J.R.1    Raymond, J.R.2    Tamir, H.3    Lauder, J.M.4
  • 101
    • 0032571016 scopus 로고    scopus 로고
    • 2+-sensitive adenylyl cyclases, key regulators of cellular signalling
    • 2+-sensitive adenylyl cyclases, key regulators of cellular signalling. Life Sci., 62, 1647-1652.
    • (1998) Life Sci. , vol.62 , pp. 1647-1652
    • Mons, N.1    Decorte, L.2    Jaffard, R.3    Cooper, D.M.4
  • 103
    • 0028988859 scopus 로고
    • Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: Glycine 22 to serine 22 and isoleucine 28 to valine 28
    • Nakhai, B., Nielsen, D.A., Linnoha, M. & Goldman, D. (1995). Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: glycine 22 to serine 22 and isoleucine 28 to valine 28. Biochem. Biophys. Res. Commun., 210, 530-536.
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , pp. 530-536
    • Nakhai, B.1    Nielsen, D.A.2    Linnoha, M.3    Goldman, D.4
  • 109
  • 112
    • 0027398771 scopus 로고
    • 1A receptors that are negatively coupled to adenylate cyclase in permanently transfected HeLa cells
    • 1A receptors that are negatively coupled to adenylate cyclase in permanently transfected HeLa cells. Biochem. Pharmacol., 45, 375-382.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 375-382
    • Pauwels, P.J.1    Van Gompel, P.2    Leysen, J.E.3
  • 113
    • 0019394689 scopus 로고
    • 3H]5-hydroxytryptamine binding sites by the neuroleptic in spiperone in rat brain
    • 3H]5-hydroxytryptamine binding sites by the neuroleptic in spiperone in rat brain. J. Neurochem., 36, 220-226.
    • (1981) J. Neurochem. , vol.36 , pp. 220-226
    • Pedigo, N.W.1    Yamamura, H.I.2    Nelson, D.3
  • 114
    • 0025357878 scopus 로고
    • Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron
    • Pennington, N.J. & Kelly, J.S. (1990). Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron. Neuron, 4, 751-758.
    • (1990) Neuron , vol.4 , pp. 751-758
    • Pennington, N.J.1    Kelly, J.S.2
  • 115
    • 0342506491 scopus 로고    scopus 로고
    • 1A receptor: Comparison of its binding properties in transfected cells and cortical tissue
    • 1A receptor: comparison of its binding properties in transfected cells and cortical tissue. Gen. Pharmacol., 29, 737-747.
    • (1997) Gen. Pharmacol. , vol.29 , pp. 737-747
    • Pou, C.1    Nenonene, E.K.2    Reader, T.A.3    Fargin, A.4
  • 123
    • 0027936264 scopus 로고
    • 1A receptor and augments its desensitization by protein kinase C in CHO cells
    • 1A receptor and augments its desensitization by protein kinase C in CHO cells. Biochemistry, 33, 11264-11269.
    • (1994) Biochemistry , vol.33 , pp. 11264-11269
    • Raymond, J.R.1    Olsen, C.L.2
  • 127
  • 132
    • 0021910792 scopus 로고
    • Two 5-HT receptors linked to adenylate cyclase in guinea pig hippocampus are discriminated by 5-carboxamidotryptamine and spiperone
    • Shenker, A., Maayani, S., Weinstein, H. & Green, J.P. (1985). Two 5-HT receptors linked to adenylate cyclase in guinea pig hippocampus are discriminated by 5-carboxamidotryptamine and spiperone. Eur. J. Pharmacol., 109, 427-429.
    • (1985) Eur. J. Pharmacol. , vol.109 , pp. 427-429
    • Shenker, A.1    Maayani, S.2    Weinstein, H.3    Green, J.P.4
  • 133
    • 0031849145 scopus 로고    scopus 로고
    • Cortisol, hypothermic and behavioral responses to ipsapirone in patients with bipolar depression and normal controls
    • Shiah, I.S., Yatham, L.N., Lam, R.W., Tam, E.M. & Zis, A.P. (1998). Cortisol, hypothermic and behavioral responses to ipsapirone in patients with bipolar depression and normal controls. Neuropsychobiology, 38, 6-12.
    • (1998) Neuropsychobiology , vol.38 , pp. 6-12
    • Shiah, I.S.1    Yatham, L.N.2    Lam, R.W.3    Tam, E.M.4    Zis, A.P.5
  • 137
    • 0024344941 scopus 로고
    • Identification of two serine residues involved in agonist activation of the β-adrenergic receptor
    • Strader, C.D., Candelore, M.R., Hill, W.S., Sigal, I.S. & Dixon, R.A.F. (1989). Identification of two serine residues involved in agonist activation of the β-adrenergic receptor. J. Biol. Chem., 264, 13572-13578.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13572-13578
    • Strader, C.D.1    Candelore, M.R.2    Hill, W.S.3    Sigal, I.S.4    Dixon, R.A.F.5
  • 138
    • 0028174325 scopus 로고
    • i2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma (NG108-15) cells
    • i2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma (NG108-15) cells. J. Biol. Chem., 269, 14307-14313.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14307-14313
    • Strassheim, D.1    Malbon, C.C.2
  • 140
    • 0028856362 scopus 로고
    • 3H]lisuride labels free receptor and receptor coupled to G protein
    • 3H]lisuride labels free receptor and receptor coupled to G protein. J. Neurochem., 65, 1909-1906.
    • (1995) J. Neurochem. , vol.65 , pp. 1909-11906
    • Sundaram, H.1    Turner, J.D.2    Strange, P.G.3
  • 141
    • 0031604113 scopus 로고    scopus 로고
    • Type-specific regulation of mammalian adenylyl cyclases by G protein pathways
    • Taussig, R. & Zimmerman, G. (1998). Type-specific regulation of mammalian adenylyl cyclases by G protein pathways. Adv. Second Messenger Phosphorortien Res., 32, 81-98.
    • (1998) Adv. Second Messenger Phosphorortien Res. , vol.32 , pp. 81-98
    • Taussig, R.1    Zimmerman, G.2
  • 145
    • 0027010262 scopus 로고
    • 1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis
    • 1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis. Mol. Biol. Cell, 9, 961-969.
    • (1992) Mol. Biol. Cell , vol.9 , pp. 961-969
    • Varrault, A.1    Bockaert, J.2    Waeber, C.3
  • 148
    • 0033555909 scopus 로고    scopus 로고
    • Cross-modulation of synaptic plasticity by β-adrenergic and 5-HT1A receptors in the rat basolateral amygdala
    • Wang, S.J., Cheng, L.L. & Gean, P.W. (1999). Cross-modulation of synaptic plasticity by β-adrenergic and 5-HT1A receptors in the rat basolateral amygdala. J. Neurosci., 19, 570-577.
    • (1999) J. Neurosci. , vol.19 , pp. 570-577
    • Wang, S.J.1    Cheng, L.L.2    Gean, P.W.3
  • 150
    • 0026357342 scopus 로고
    • Role of serotonin and other neurotransmitter receptors in brain development. Basis for developmental pharmacology
    • Whitaker-Azmitia, P.M. (1991). Role of serotonin and other neurotransmitter receptors in brain development. Basis for developmental pharmacology. Pharmacol. Rev., 43, 347-352.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 347-352
    • Whitaker-Azmitia, P.M.1
  • 151
    • 0026611045 scopus 로고
    • 2-mediated hormonal inhibition of cyclic AMP accumulation
    • 2-mediated hormonal inhibition of cyclic AMP accumulation. Science, 255, 339-342.
    • (1992) Science , vol.255 , pp. 339-342
    • Wong, Y.H.1    Conklin, B.R.2    Bourne, H.R.3
  • 152
    • 0032103201 scopus 로고    scopus 로고
    • Effects of adrenalectomy on hyperphagia-induced by the 5-HT1A receptor agonists 8-OH-DPAT and 2-deoxy-D-glucose in rats
    • Yamada, J., Sugimoto, Y. & Yoshikawa, T. (1998). Effects of adrenalectomy on hyperphagia-induced by the 5-HT1A receptor agonists 8-OH-DPAT and 2-deoxy-D-glucose in rats. Neuroreport. 9, 1831-1833.
    • (1998) Neuroreport , vol.9 , pp. 1831-1833
    • Yamada, J.1    Sugimoto, Y.2    Yoshikawa, T.3
  • 153
    • 0030916968 scopus 로고    scopus 로고
    • Molecular cloning of 5-hydroxytryptamine (5-HT) type 1 receptor genes from the japanese puffer fish
    • Yamaguchi, E. & Brenner, S. (1997). Molecular cloning of 5-hydroxytryptamine (5-HT) type 1 receptor genes from the Japanese puffer fish. Fugu rubripes. Gene, 191, 219-223.
    • (1997) Fugu Rubripes. Gene , vol.191 , pp. 219-223
    • Yamaguchi, E.1    Brenner, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.