Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial

American Journal of Geriatric Psychiatry

Volumn 5, Issue 2, 1997, Pages 97-106

  Schneider, Lon S ^a,b   Small, Gary W ^a   Hamilton, Susan H ^a   Bystritsky, Alexander ^a   Nemeroff, Charles B ^a   Meyers, Barnett S ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b HMR 101 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONJUGATED ESTROGEN; ESTRADIOL; ESTROGEN; ETHINYLESTRADIOL; FLUOXETINE; MEDROXYPROGESTERONE; METHYLTESTOSTERONE; PIPERAZINE ESTRONE SULFATE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ESTROGEN THERAPY; FEMALE; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; POSTMENOPAUSE; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TRANSDERMAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

EID: 12644318801     PISSN: 10647481     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019442-199721520-00002     Document Type: Article

References (32)

1. Paul SM, Axelrod J, SaavedraJM, et al: Estrogen-induced efflux of endogenous catecholamines from the hypothalamus in vitro. Brain Res 1979; 178:499-505
2. Luine VN, Khylchevskaya R, McEwen BS: Effect of gonadal steroids on activities of monoamine oxidase and choline acetylase in rat brain. Brain Res 1975; 86:293-306
3. Kendall DA, Stancel GM, Enna SJ: Imipramine: effect of ovarian steroids on modifications in serotonin receptor binding. Science 1981; 211:1183-1185
4. Klaiber EL, Broverman DM, Vogel W, et al: Estrogen therapy for severe, persistent depressions in women. Arch Gen Psychiatry 1979; 36:550-554
5. Ditkoff EC, Crary WG, Cristo M, et al: Estrogen improves psychological function in asymptomatic postmenopausal women. Obstet Gynecol 1991; 78:991-995
6. Sherwin BB: Affective changes with estrogen and androgen replacement therapy in surgically menopausal women. J Affect Disord 1988; 14:177-187
7. Tollefson GD, Bosomworth JC, Heiligenstein JH, et al: A double-blind, placebo-controlled clinical trial of fluoxetine in geriatric patients with major depression. Int Psychogeriatr 1995; 7:89-104
8. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 3rd Edition, Revised. Washington, DC, American Psychiatric Association, 1987
9. Hamilton M: Development of a rating scale for primary depressive illness. Br J Soc Psychol 1967; 6:278-296
10. Folstein M, Folstein S, McHugh P: Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198
11. Brink TL, Yesavage JA, Lum O, et al: Screening tests for geriatric depression. Clinical Gerontology 1982; 1:37-43
12. SAS Institute Inc.: SAS/STAT User's Guide, Version 6, 4th Edition. Cary, NC, SAS Institute, Inc., 1989
13. Anthony JC, Aboraya A: The epidemiology of selected mental disorders in later life, in Handbook of Mental Health and Aging, 2nd Edition. Edited by Birren JE, Sloane RB, Cohen GD. New York, Academic Press, 1992, pp 27-73
14. Palinkas LA, Barrett-Connor E: Estrogen use and depressive symptoms in postmenopausal women. Obst Gynecol 1992; 80:30-36
15. Salzman C: Pharmacological treatment of depression in elderly patients, in Diagnosis and Treatment of Depression in Late Life: Results of the NIH Consensus Development Conference. Edited by Schneider LS, Reynolds CF, Lebowitz BD, et al. Washington, DC, American Psychiatric Press, 1994, pp 181-224
16. Reynolds CF, Schneider LS, Lebowitz BD, et al: Treatment of depression in the elderly: guidelines for primary care, in Diagnosis and Treatment of Depression in the Elderly: Proceedings of the NIH Consensus Development Conference. Edited by Schneider LS, Reynolds CF, Lebowitz BD, et al. Washington, DC, American Psychiatric Press, 1994, pp 463-490
17. Simpkins JW, Singh M, Bishop J: The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease. Neurobiol Aging 1994; 15(suppl 2):S195-S197
18. Luine V: Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 1985; 89:484-490
19. Alexopoulos GS, Young RC, Lieberman KW, et al: Platelet MAO activity in geriatric patients with depression and dementia. Am J Psychiatry 1987; 144:1480-1483
20. Schneider IS, Severson JA, Pollock V, et al: Platelet monoamine oxidase activity in elderly depressed outpatients. Biol Psychiatry 1986; 21:1360-1364
21. Alexopoulos GS, Lieberman KW, Young RC: Platelet MAO activity in primary degenerative dementia. Am J Psychiatry 1984; 141:97-99
22. Adolffson R, Gotffries CG, Oreland L, et al: Increased activity of brain and platelet monoamine oxidase in dementia of Alzheimer type. Life Sci 1980; 27:1029-1034
23. Schneider LS, SeversonJ, Chui H, et al: Platelet tritiated imipramine binding and MAO activity in Alzheimer's patients with agitation and delusions. Psychiatry Res 1988; 25:311-322
24. Tatton WG: "Trophic-like" reduction of nerve cell death by deprenyl without monoamine oxidase inhibition. Neurol Forum 1993; 4:3-10
25. Knoll J: Striatal dopamine dependency of lifespan in male rats. Mechanisms of Aging and Development 1988; 46;237-262
26. Milgram NW, Racine RJ, Nellis P, et al: Maintenance on L-deprenyl prolongs life in aged male rats. Life Sci 1990; 47:415-420
27. Ripley HS, Shorr E, Papanicolaou GN: The effect of treatment of depression in the menopause with estrogenic hormone. Am J Psychiatry 1940; 96:905-915
28. Shapira B, Oppenheim G, Zohar J, et al: Lack of efficacy of estrogen supplementation to imipramine in resistant female depressives. Biol Psychiatry 1985; 20:576-579
29. Ross RK, Paganini-Hill A, Mack TM, et al: Cardiovascular benefits of estrogen replacement therapy. Am J Obstet Gynecol 1989; 160:1301-1306
30. Manolio TA, Furberg CD, Shemanski L, et al: Associations of postmenopausal estrogen use with cardiovascular disease and its risk factors in older women. Circulation 1993; 88(part 1):2163-2171
31. Schneider LS, Small GW, Farlow M, et al: Does estrogen augment psychopharmacologic response in elderly patients? American College of Neuropsychopharmacology, 33rd Annual Meeting. San Juan, PR. December 12-16, 1994
32. Belchetz PE: Hormonal treatment of postmenopausal women. New Engl J Med 1994; 330: 1062-1071