Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients

Biological Psychiatry

Volumn 50, Issue 2, 2001, Pages 123-128

  Nishiguchi, Naoki ^a,b   Matsushita, Sachio ^a   Suzuki, Kenji ^a   Murayama, Masanobu ^c   Shirakawa, Osamu ^b   Higuchi, Susumu ^a  

^a KURIHAMA NATIONAL HOSPITAL   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Akagi Kougen Hospital   (Japan)

Author keywords

Association; Borderline personality disorder; Disinhibition; Eating disorder; Gene; Japanese patients; Serotonin 2A receptor

Indexed keywords

SEROTONIN 2A RECEPTOR;

ADULT; ANOREXIA NERVOSA; ARTICLE; BORDERLINE STATE; BULIMIA; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEEDING BEHAVIOR; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; PERSONALITY; PREVALENCE; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0035878558     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(00)01107-0     Document Type: Article

References (39)

1. Evidence that 1-(2, 5-dimethoxy-4-methylphenyl)-2-aminopropane-induced hypophagia and hyperthermia in rats is mediated by serotonin-2A receptors
2. Is there a role for serotonin (5-hydroxy-tryptamine) in feeding?
3. Serotonin and appetite
4. Serotonin manipulations and the structure of feeding behaviour
5. Serotonin in eating disorders
6. Testmeal responses following m- chlorophenylpiperazine and L-tryptophan in bulimics and controls
7. Lack of association between 5-HT2A gene promoter polymorphism and susceptibility to anorexia nervosa
8. Neurogenetic adaptive mechanisms in alcoholism
9. Association between 5-HT2A gene promoter polymorphism and anorexia nervosa
10. 5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder
11. Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: Identification of two naturally occurring receptor variants and association analysis in schizophrenia
12. Oestrogen and mental state
13. The heterogeneity of anorexia nervosa: Bulimia as a distinct subgroup
14. The eating attitudes test: Psychometric features and clinical correlates
15. Stimulation of 5-HT2A receptors in the paraventricular hypothalamus attenuates neuropeptide Y-induced hyperphagia through activation of corticotropin releasing factor
16. Comorbidity and outcome in eating disorders
17. 5-HT2A receptor gene polymorphisms, anorexia nervosa, and obesity
18. Anorexia nervosa: Evidence for a genetic basis
19. Family history study of anorexia nervosa and bulimia
20. Pattern of onset of bulimic symptoms in anorexia nervosa
21. Psychiatric disorders in the first-degree relatives of probands with bulimia nervosa
22. The genetic epidemiology of bulimia nervosa
23. Personality disorders in anorexia nervosa and bulimia nervosa
24. An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in rats
25. Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior
26. 5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa
27. Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence
28. Serotonin 2A receptor gene polymorphism in suicide victims
29. Two naturally occurring amino acid substitutions of the 5-HT2A receptor: Prevalence in patients with seasonal affective disorder and controls
30. Chlorophenylpiperazine: A central serotonin agonist causing powerful anorexia in rats
31. Serotonergic mechanisms in human feeding: The pharmacological evidence
32. 5-HT2A promoter polymorphism in anorexia nervosa
33. A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphism in the promoter
34. Family-genetic studies of eating disorders
35. Characterization of the human 5-HT2A receptor gene promoter
36. 2A gene promoter polymorphism and susceptibility to eating disorders and a meta-analysis pertaining to anorexia nervosa