Thioredoxin as a potent costimulus of cytokine expression

Journal of Immunology

Volumn 156, Issue 2, 1996, Pages 765-771

  Schenk, Heike ^a   Vogt, Markus ^b   Dröge, Wulf ^a   Schulze Osthoff, Klaus ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; THIOREDOXIN;

ANIMAL CELL; ARTICLE; MONOCYTE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CYTOKINES; FIBROSARCOMA; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-1; INTERLEUKIN-6; INTERLEUKIN-8; MICE; MONOCYTES; OXIDATION-REDUCTION; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; STIMULATION, CHEMICAL; TETRADECANOYLPHORBOL ACETATE; THIOREDOXIN; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030030918     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Dröge, W , K. Schulze-Osthoff, S. Mihm, D. Galter, H. Schenk, H.-P. Eck, S. Roth, and H. Gmunder. 1994. Functions of glutathione and glutathione disulfide in immunology and immunopathology FASEB J. 14:1131.
2. Pahl, H L , and P. A. Baeuerle. 1994. Oxygen and the control of gene expression. Bioessays 16:497.
3. Roth, S., and W. Droge 1987. Regulation of T cell growth factor (TCGF) production by hydrogen peroxide. Cell. Immunol 108:417.
4. Koga, S., S. Ogawa, K. Kuwabara, J. Brett, J A. Leavy, J. Ryan, Y. Koga, J. Plocinski, W. Benjamin, D. K Burns, and D. Stern. 1992. Synthesis and release of interleukin-1 by reoxygenated human mononuclear phagocytes. J. Clin. Invest 90:100.
5. Lo, S. K., K. Janakidevi, L. Lai, and A. B. Malik. 1993. Hydrogen peroxide-induced increase in endothelial adhesiveness is dependent on ICAM-1 activation. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8) L406.
6. Cerutti, P. A. 1991. Oxidant stress and carcinogenesis Eur J. Clin. Invest. 21:1.
7. Nose, K., M. Shibanuma, K. Kikuchi, H. Kageyama, S. Sakiyama, and T Kuroki. 1991. Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line. Eur J. Biochem. 201:99.
8. Schreck, R., P. Rieber, and P. A. Baeuerle. 1991. Reactive oxygen species intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J. 10.224.
9. Mihm, S., J. Ennen, U. Pessara, R. Kurth, and W. Droge. 1991. Inhibition of HIV-1 replication and NF-κB activity by cysteine and cysteine derivatives. AIDS 5:497.
10. Schulze-Osthoff, K., R Beyaert, V Vandevoorde, G. Haegeman, and W. Fiers. 1993. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of tumor necrosis factor EMBO J. 12:3095.
11. Ziegler-Heitbrock, H. W. L., T. Sternsdorf, J. Liese, B. Belohradsky, C. Weber, A. Wedel, R. Schreck, P Baeuerle, and M. Strobel. 1993. Pyrrolidine dithiocarbamate inhibits NF-κB mobilization and tumor necrosis factor production in human monocytes J. Immunol 151:6986
12. Costello, R , C. Lipcey, M. Algarté, C Cerdan, P A. Baeuerle, D. Olive, and J. Imbert. 1993 Activation of primary human T lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-κB. Cell Growth Differ 4:329.
13. DeForge, L. E., J C Fantone, J. S. Kenney, and D. Remick. 1992. Oxygen radical scavengers selectively inhibit interleukin-8 production in human whole blood J. Clin. Invest 90:2123.
14. Dröge, W., H -P. Eck, and S Mihm. 1992 HIV-induced cysteine deficiency and T cell dysfunction: a rationale for treatment with N-acetyl-cysteine. Immunol. Today 13:211.
15. Staal, F. J., S W. Ela, M. Roederer, M T. Anderson, L. A. Herzenberg, and L A Herzenberg 1992. Glutathione deficiency and human immunodeficiency virus infection. Lancet 339:909.
16. Schenk, H., M. Klein, W. Erdbrügger, W. Dröge, and K. Schulze-Osthoff. 1994 Distinct effects of thioredoxin and other antioxidants on the activation of NF-κB and AP-1 Proc. Natl. Acad. Sci USA 91:1672.
17. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor EMBO J. 12:2005.
18. Baeuerle, P. A., and T Henkel. 1994. Function and activation of NF-κB in the immune system Annu. Rev. Immunol. 12:141.
19. Holmgren, A. 1985. Thioredoxin Annu Rev Biochem. 54.237.
20. Holmgren, A. 1989. Thioredoxin and glutaredoxin systems J. Biol. Chem 264. 13963.
21. Grippo, J F., A. Holmgren, W B. Pratt 1985 Proof that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin J Biol. Chem 260: 93
22. Tagaya, Y , Y Maeda, A. Mitsui, N. Kondo, H. Matsui, J Hamuro, J. Brown, K. I. Arai, T. Yokota, H. Wakasugi, and J. Yodoi. 1989 Adult T cell leukemia-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin Possible involvement of dithiol- reduction in the IL-2 receptor induction. EMBO J 8:757
23. Wakasugi, N , Y. Tagaya, H. Wakasugi, A. Mitsui, M. Maeda, J. Yodoi, and T. Tursz. 1990. ADF/thioredoxin produced by both HTLV-I and EBV-transformed lymphocytes acts as an autocrine growth factor and synergizes with IL-1 and IL-2. Proc Natl. Acad. Sci USA 87.8282.
24. Ericson, M. L., J. Hörling, V. Wendel-Hansen, A. Holmgren, and A. Rosen 1992. Secretion of thioredoxin after in vitro activation of human B cells. Lymphokine Cytokine Res. 5:201.
25. Yodoi, J., and T. Uchiyama. 1992 Diseases associated with HTLV-I virus, IL-2 receptor dysregulation, and redox regulation Immunol. Today 13:405.
26. Yodoi, J., and T. Tursz 1991. ADF, a growth-promoting factor derived from adult T cell leukemia and homologous to thioredoxin: involvement in lymphocyte immortalization by HTLV-1 and EBV. Adv. Cancer Res. 57:381.
27. Tagaya, Y., H Wakasugi, H Masutani, H. Nakamura, S. Iwata, A. Mitsui, S. Fujii, N Wakasugi, T. Tursz, and J. Yodoi. 1990. Role of ATL-derived factor (ADF) in the normal and abnormal cellular activation: involvement of dithiol-related reduction Mol. Immunol. 27:1279.
28. Holmgren, A. 1979. Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide J. Biol. Chem. 254:9627.
29. Montesano, R., M. S. Pepper, U. Mohle-Steinlein, W Risau, E F. Wagner, and L Orci. 1990. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell 62:435.
30. Ziegler-Heitbrock, H. W. L., E. Thiel, A. Fütterer, V. Herzog, A Wirtz, and G. Riethmüller. 1988. Establishment of a human cell line (Mono Mac6) with characteristics of mature monocytes. Int. J. Cancer 41:456.
31. Sundstrom, C., and K Nilsson. 1976. Establishment and characterization of a human histiocytic lymphoma cell tine (U-937). Int. J. Cancer 17:565.
32. Takada, A., Y. Takada, and I. Minowada. 1974. Immunologic functions of human T lymphoid cell line (Molt) I Release of immunosuppressive factors from the mixture of Molt-4 and sheep red blood cells. J. Exp. Med. 140:538.
33. Kaye, J , S. Porcelli, J. Tite, B Jones, and C. A. Janeway. 1983. Both a monoclonal antibody and antisera specific for determinants unique for individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells. J. Exp. Med. 158:836.
34. Gillis, S , M. Ferm, W. Ou, and K. Smith. 1978. T cell growth factor: parameters of production and a quantitiative microassay for activity. J. Immunol. 120:2027.
35. 2-terminal amino acid sequence of a T cell-derived lymphokine with growth factor activity for B cell hybridomas Proc Natl. Acad Sci. USA 83:9679.
36. Tada, H., O. Shiho, K. Kuroshima, M. Koyama, and K. Tsukamoto. 1986 An improved colorimetric assay for interleukin-2. J. Immunol. Methods 93.157
37. Chomczynski, P., and N Sacchi. 1987. Single-step method of RNA isolation by acidic guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem 162 156.
38. Newman, G. W , M K. Balcewicz-Sablinska, J. R Guarnaccia, H G. Reinold, and D. S. Silberstein. 1994 Opposing regulatory effects of thioredoxin and eosinophil cytotoxicity-enhancing factor on the development of human immunodeficiency virus 1. J. Exp. Med 180 359.
39. Rosen, A., C. Uggla, R. Szigeti, B. Kallin, C Lindquist, and J. Zeuthen. 1986. A T helper cell X Molt-4 human hybridoma constitutively producing B cell stimulatory and inhibitory factors Lymphokine Res. 5.185.
40. Silberstein, D. S , M. Ali, S L. Baker, and J. R. David 1989. Human eosinophil cytotoxicity-enhancing factor. Purification, physical characteristics, and partial amino acid sequence of an active polypeptide J. Immunol. 143:979
41. East, C. J., C. N. Abboud, and R F Borch. 1992. Diethyldithiocarbamate induction of cytokine release in human long-term bone marrow cultures. Blood 80. 1172
42. Chen, Q., K Yu, N J. Holbrook, and J. L. Stevens 1992. Activation of the growth arrest and DNA damage-inducible gene gadd153 by nephrotoxic cysteine conjugates and dithiothreitol. J Biol. Chem. 267.8207
43. Okamoto, T., H Ogiwara, T. Hayashi, A Mitsui, T. Kawabe, and J. Yodoi. 1992. Human thioredoxin/adult T cell leukemia-derived factor activates the enhancer binding protein of human immunodeficiency virus type 1 by thiol redox control mechanism. Int. Immunol. 4.811.
44. Toledano, M. B , and W. J. Leonard. 1991. Modulation of transcription factor NF-κB binding by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. USA 88: 4328.
45. Kumar, S., A. B. Rabson, and C. Gélinas. 1992. The RxxRxRxxC motif conserved in all Rel/κB proteins is essential fur the DNA-binding activity and redox regulation of the v-Rel oncoprotein. Mol. Cell. Biol. 12:3094
46. Xanthoudakis, S., G. Miao, F. Wang, Y.-C. E. Pan, and T. Curran. 1992. Redox activation of Fos-Jun DNA-binding activity is mediated by a DNA repair enzyme. EMBO J. 11:3323.
47. Akira, S., and T. Kishimoto 1992. Interleukin (IL)-6 and NF-IL-6 in acute-phase response and viral infection. Immunol. Rev. 127:25.
48. Rao, A. 1994 NF-ATp: a transcription factor required for the coordinate induction of several cytokine genes. Immunol. Today 15-274.
49. Bensi, G , M. Mora, G. Raugei, D. Bounamassa, M. Rossini, and M. Melli 1990. An inducible enhancer controls the expression of the human interleukin-1β gene. Cell Growth Differ. 1:491.
50. Jain, J., V. E. Valge-Archer, and A Rao. 1992. Analysis of the AP-1 sites in the IL-2 promoter J. Immunol. 148:1240.
51. Rhoades, K. L , S H. Golub, and J S. Economou. 1992 The regulation of the human tumor necrosis factor-α promoter region in macrophages, T cell, and B cell lines. J. Biol. Chem. 267 22102.