Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen

Toxicological Sciences

Volumn 52, Issue 2, 1999, Pages 189-198

  Coutant, Karine D ^a   De Fraissinette, Anne Brugerolle De ^a   Cordier, André ^a   Ulrich, Peter ^a,b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b WSH 2881329a   (Switzerland)

Author keywords

Chemical haptens; Dendritic cells; Human

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALLERGEN; AMINOPHENOL; BENZOIC ACID; CHLORPROMAZINE; CYTOKINE; DODECYL SULFATE SODIUM; HAPTEN; HLA DR ANTIGEN; LIPOPOLYSACCHARIDE; NICKEL SULFATE; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN;

ARTICLE; CELL ACTIVATION; CELL ACTIVITY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOTOXICITY; MONOCYTE; PHENOTYPE;

EID: 0342905089     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/52.2.189     Document Type: Article

References (21)

1. Aiba S., Terunuma, A., Manome, H., and Tagami, H. (1997). Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur. J. Immunol. 27, 3031-3038.
2. Basketter, D., Dooms-Goossens, A., Karlberg, A. T., and Lepoittevin, J. P. (1995). The chemistry of contact allergy: Why is a molecule allergenic? Contact Dermatitis 32, 65-73.
3. Botham, P. A., Rattray, N. J., Walsh, S. T. ,and Riley, E. J. (1987). Control of the immune response to contact sensitizing chemicals by cutaneous antigen-presenting cells. Br. J. Dermatol. 117, 1-9.
4. Brander, C., Mauri-Hellweg, D., Bettens, F., Rolli, H., Goldman, M., and Pichler, W. J. (1995). Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals. J. Immunol. 155, 2670-2678.
5. Buelens, C., Verhasselt, V., De Groote, D., Thielemans, K., Goldman, M., and Willems, F. (1997). Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin-10. Eur .J. Immunol. 27, 1848-1852.
6. Cella, M., Sallusto, F., and Lanzavecchia, A. (1997). Origin, maturation, and antigen-presenting function of dendritic cells. Curr. Opin. Immunol. 9, 10-16.
7. Chapuis, F., Rosenzwajg, M., Yagello, M., Ekman, M., Biberfeld, P.,and Gluckman, J. C. (1997). Differentiation of human dendritic cells from monocytes in vitro. Eur. J. Immunol. 27, 431-441.
8. Chen, B., Shi, Y., Smith, J. D., Choi, D., Geiger. J. D., and Mule, J. J. (1998). The role of tumor necrosis factor alpha in modulating the quantity of peripheral blood-derived, cytokine-driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting soluble antigens to CD4+ T cells in vitro. Blood 91, 4652-4661.
9. De Saint-Vis B., Fugier, V.,I., Massacrier, C., Gaillard, C., Vanbervliet, B., Ait, Y. S., Banchereau, J., Liu, Y. J., Lebecque, S., and Caux, C. (1998). The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation. J. Immunol. 160, 1666-1676.
10. De Weck, A. L. (1983). Immunopathological mechanisms and clinical aspects of allergic reactions to drugs. In Allergic Reactions to Drugs (A. L. De Weck and H. Bundgaard, Eds.), pp. 75-133. Springer-Verlag, Berlin Heidelberg.
11. Enk, A. H., and Katz, S. I. (1992). Early molecular events in the induction phase of contact sensitivity. Proc. Natl. Acad. Sci.U S A 89, 1398-1402.
12. Kimber, I., Dearman, R. J., Scholes, E. W., and Basketter, D. A. (1994). The local lymph node assay: developments and applications. Toxicology 93, 13-31.
13. Ma, X., Aste-Amezaga, M., and Trinchieri, G. (1996). Regulation of interleukin-12 production. Ann. NY Acad. Sci. 795, 13-25.
14. Marrack, P., and Kappler, J. (1990). The staphylococcal enterotoxins and their relatives. Science 248, 1066.
15. Matsuyama, S., Koide, Y., and Yoshida, T. O. (1993). HLA class II molecule-mediated signal transduction mechanism responsible for the expression of interleukin-1β and tumor necrosis factor-α genes induced by a staphylococcal superantigen. Eur. J. Immunol. 23, 3194-3202.
16. Meierhoff, G., and Krause, S.W.A.R. (1998). Comparative analysis of dendritic cells derived from blood monocytes or CD34+ hematopoietic progenitor cells. Immunobiology 198, 501-513.
17. Rambukkana, A., Pistoor, F. H., Bos, J. D., Kaspenberg, M. L., and Das, P. K. (1996). Effects of contact allergens on human Langerhans cells in skin organ culture: Migration, modulation of cell surface molecules, and early expression of interleukin-1β protein. Lab. Invest. 74, 422-436.
18. Romani, N., Lenz, A., Glassel, H., Stossel, H., Stanzl, U., Majdic, O., Fritsch, P. and Schuler, G. (1989). Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and function. J. Invest. Dermatol. 93. 600-609.
19. Sallusto, F., and Lanzavecchia, A. (1994). Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and down-regulated by tumor necrosis factor alpha. J. Exp. Med. 179, 1109-1118.
20. Steinman, R. M. (1991). The dendritic cell system and its role in immunogenicity. Annu. .Rev. Immunol. 9, 271-296.
21. Verhasselt, V., Buelens, C., Willems, F., De Groote, D., Haeffner-Cavaillon, N., and Goldman, M. (1997). Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: Evidence for a soluble CD14-dependent pathway. J. Immunol. 158, 2919-2925.