Oxidative stress regulates the expression and activity of transcription factor activator protein-1 in rat conceptus

Journal of Pharmacology and Experimental Therapeutics

Volumn 280, Issue 2, 1997, Pages 1085-1093

  Ozolinsš, Terence R S ^a   Hales, Barbara F ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENYLHYDRAZINE; ALPHA TOCOPHEROL; CATALASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MESSENGER RNA; ONCOPROTEIN; SUPEROXIDE DISMUTASE; TERATOGENIC AGENT; TRANSCRIPTION FACTOR AP 1;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; EMBRYO; IMMEDIATE EARLY GENE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C JUN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; RAT; TERATOGENESIS; TISSUE SPECIFICITY; YOLK SAC;

ANIMALS; BASE SEQUENCE; BINDING SITES; COLLAGENASES; FEMALE; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTATHIONE; HUMANS; OLIGODEOXYRIBONUCLEOTIDES; ORGAN CULTURE TECHNIQUES; OXIDATIVE STRESS; PREGNANCY; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; YOLK SAC;

EID: 14444270850     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (71)

1. ABATE, C., PÁTEL, L., RAUSCHER, F. J., III AND CURRAN, T.: Redox regulation of Fos and Jun DNA-binding activity in vitro. Science (Wash, DC) 249: 1157-1161, 1990.
2. AMSTAD, P. A., KRLTITZA, G. AND CERUTTI, P. A.: Mechanism of c-fos induction by active oxygen. Cancer Res. 52: 3952-3960, 1992.
3. ANDERSON, G. M. AND FRKYTAG.;, S. O.: Synergistic activation of a human promotor in vivo by transcription factor Sp1. Mol. Cell. Biol. 11: 1935-1943, 1991.
4. ANDREWS, G. K., MARDINO, M. A., CALVET, J. P. AND ADAMSON, E. D.: Heat shock response in HeLa cells is accompanied by elevated expression of the c-fos proto-oncogene. Mol. Cell. Biol. 7: 3452-3458, 1987.
5. ANGKL, P., ALLEGRETTO, E. A., OKINO, S. T., HATTORI, K., BOYLE, W. J., HUNTER, T. AND KARIN, M.: Oncogene jun encodes a sequence-specific trans activator similar to AP-1. Nature (Lond.) 332: 166-171, 1988.
6. ANGEL, P., IMAGAWA, M., CHIU, R., STEIN, B., IMBRA, R. J., RAHMSDORF, H. J., JONAT, C., HERRLICH, P, AND KARIN, M.: Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49: 729-739, 1987.
7. ANGEL, P. AND KARIN, M.: The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 1072: 129-157, 1991.
8. BERGELSON, S., PINKUS, R. AND DANIEL, V.: Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression. Cancer Res. 54: 36-40, 1994.
9. BRADFORD, M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976.
10. BREHE, J. E. AND BURCH, H. B.: Enzymatic assay for glutathione. Anal. Biochem. 74: 189-197, 1976.
11. CAUBET, J. F.: c-fos proto-oncogene expression in the nervous system during mouse development. Mol. Cell. Biol. 9: 2269-2272, 1989.
12. CHODOSH, L. A.: Mobility shift DNA-binding assays using gel electrophoresis. In Current Protocols in Molecular Biology, ed. by F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J, A. Smith and K. Struhl, vol. 2, pp. 12.2.1-12.2.10, John Wiley and Sons, Inc., New York, 1988.
13. CHOMCZYNSKI, P. AND SACCHI, N.: Single-step method of RNA isolation by acid., guanidinium thiocyanate-phenol-chloroform extraction. Anal, Biochem. 162: 156-159, 1987.
14. CLOSS, E. T., MURRAY, A. B., SCHMIDT, J., SCHÖN, A., ERFLE, V. AND STRAUSS, P. G.: c-fos expression precedes osteogenic differentiation of cartilage cells in vitro. J. Cell. Biol. 111: 1313-1323, 1990.
15. CURRAN, T. AND FRANZA, B. R., JR.: Fos and jun: The AP-1 connection. Cell 55: 395-397, 1988.
16. DE GROOT, R. P., KRUYT, F. A. E., VAN DER SAAG, P. T. AND KRUIJER, W.: Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J. 9: 1831-1837, 1990.
17. DEMCZUK, S., HARBERS, M. AND VENNSTRÖM, B.: Identification and analsis of all components of a gel retardation assay by combination with immunoblotting. Proc. Natl. Acad. Sci. U.S.A. 90: 2574-2578, 1993.
18. DE TOGNI, P., NIMAN, H., RAYMOND, V., SAWCHENKO, P. AND VERMA, I. M.: Detection of Fos protein during osteogenesis by monoclonal antibodies. Mol. Cell. Biol. 8: 2251-2256, 1988.
19. DEVARY, Y., GOTTLIEB, R. A., SMEAL, T. AND KARIN, M.: The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell 71: 1081-1091, 1992.
20. DI ILIO, C., DEI, BOCCI, G., CASALONE, E., ACETO, A. AND SACCHETTA, P.: Activities of enzymes associated with the metabolism of glutathione in the fetal rat liver and placenta. Biol. Neonate 49: 96-101, 1986.
21. DJAVAHERI-MERGNY, M., MERONY, J.-L., BERTRAND, F., SANTUS. R., MAZIÈRE, C., DUBERTRET, L. AND MAZIÈRE, J.-C.: Ultraviolet-A induces activation of AP-1 in cultured human keratinocytes. FEBS Lett. 384: 92-96, 1996.
22. DONY, C. AND GRUSS, P.: Proto-oncogene c-fos expression in growth regions of fetal bone and mesodermal web tissue. Nature (Lond.) 328: 711-714, 1987.
23. EL-HAGE, S. AND SINGH, S. M.: Temporal expression of genes encoding free radical-metabolizing enzymes is associated with higher mRNA levels during in utero development in mice. Dev. Genet. 11: 149-159, 1990.
24. FAUSTMAN-WATTS, E. M., NAMJUNG, M. J. AND JUCHAU, M. R.: Modulation of the embryotoxicity in vitro of reactive metabolites of 2-acetylaminofluorene by reduced glutathione and ascorbate via sulfatiun. Toxicol. Appl. Pharmacol. 86: 400-410, 1986.
25. FUTSCHER, B. W. AND ERICKSON, L. C.: Changes in c-mye and c-fos expression in a human tumor cell line following exposure to bifunctional alkylating agents. Cancer Res. 50: 62-66, 1990.
26. GALTKR. D., MIHM, S. AND DROGE, W.: Distinct effects of glutathione disulfide on nuclear transcription factor κB and activator protein-1. Eur. J. Biochem. 221: 639-648, 1994.
27. GRIFFITH, O. W.: Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106: 207-212, 1980.
28. GUBITS, R. M. AND FAIRHURST, J. L.: c-fos mRNA levels are increased by the cellular Stressors, heat shock and sodium arsenite. Oncogene 3: 163-168, 1988.
29. HALES, B. F.: In vitro approaches to teratology. In In Vitro Toxicology: Mechanisms and New Technology, ed. by A. M. Goldberg, pp. 77-86, Mary Ann Liebert, Inc., New York, 1991.
30. HARRIS, C., NAMKUNG, M. J. AND JUCHAU, M. R.: Regulation of intracellular glutathione in rat embryos and viceral yolk sacs and its effects on 2-nitrosofluorene-induced malformations in the whole embryo culture system. Toxicol. Appl. Pharmacol. 88: 141-152, 1987.
31. HIGO, H., LEE, J. Y., SATOW, Y. AND HIGO, K.: Elevated expression of protooncogenes accompanies enhanced induction of heat-shock genes after exposure of rat embryos in utero to ionizing radiation. Teratogen. Carcinogen. Mutagen. 9: 191-198, 1989.
32. HILBERG, F., AGUZZI, A., HOWELLS, N. AND WAGNER, E. F.: c-Jun is essential for normal mouse development and hepatogenesis. Nature (Lond) 365: 179-181, 1993.
33. HOLT, J. T., GOPAL, T. V., MOULTON, A. D. AND NIENHUIS, A. W.: Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 83: 4794-4798, 1986.
34. JOHNSON, R. S., SPIEGELMAN, B. M. AND PAPAIOANNOU, V.: Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71: 577-586, 1992.
35. KELLER, R. J., HALMES, N. C., HINSON, J. A. AND PUMFORD, N. R.: Immunodetection of oxidized proteins. Chem. Res. Toxicol. 6: 430-433, 1993.
36. KOVARY, K. AND BRAVO, R.: The Jun and Fos protein families are both required for cell cycle progression in fibroblasts. Mol. Cell. Biol. 11: 4466-4472, 1991.
37. 4. Nature (Lond.) 227: 680-685, 1970.
38. LEE, W., MITCHEL, P. AND TJIAN, R.: Purified transcription factor AP-1 interacts with TPA inducible enhancer elements. Cell 49: 741-752, 1987.
39. LU, Y. Y. C. AND CRUZ, T. F.: Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J. Biol. Chem. 270: 11727-11730, 1995.
40. i in induction of c-fos, c-jun and c-myc mRNA in rat PTE after oxidative stress. FASEB J. 6: 919-924, 1992.
41. MEISTER, A.: Glutathione and the γ-glutamyl cycle. In Glutathione: Metabolism and Function, ed. by I. M. Arias, and W. B. Jackoby, pp. 35-44, Raven Press, New York, 1976.
42. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-response factor. EMBO J. 12: 2005-2015, 1993.
43. MILLER, A. D., CURRAN, T. AND VERMA, I. M.: c-Fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene. Cell 36: 51-60, 1984.
44. MÜLLER, R., BRAVO, R., BURCKHARDT, J. AND CURHAN, T.: Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature (Lond.) 312: 716-720, 1984.
45. MÜLLER, R., SLAMON, D. J., TREMBLAY, J. M., CLINE, M. J. AND VERMA, I. M.: Differential expression of cellular oncogenes during pre- and postnatal development of the mouse. Nature (Lond.) 299: 640-644, 1982.
46. NEW, D. A. T.: Whole embryo culture and the study of mammalian development during organogenesis. Biol. Rev. 53: 81-122, 1978.
47. NIELSON, L. L., WERB, Z. AND PEUERSON, R. A.: Induction of c-fos transcripts in early postimplantation embryos by TGFα, EGF, PDGF and FGF. Mol. Reprod. Dev. 29: 227-237, 1991.
48. NISHIKURA, K. AND MURRAY, J. M.: Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells. Mol. Cell. Biol. 7: 639-649, 1987.
49. OZOLINŠ, T. R. S., SIKSAY, D. L. A. AND WELLS, P. G.: Modulation of embryonic glutathione peroxidaae activity and phenytoin teratogenicity by dietary deprivation of selenium in CD-1 mice. J. Pharmacol. Exp. Ther. 277: 945-953, 1996.
50. PAL, S. K., CROWELL, R., KIESSUNO, A. A. AND COOPER, G. M.: Expression of proto-oncogenes in mouse eggs and preimplantation embryos. Mol. Reprod. Dev. 35: 8-15, 1993.
51. RAO, G. N., LASSÉGUE, B., GRIENDLING, K. K., ALEXANDER R. W. AND BERK, B. C.: Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: Role of protein kinase C. Nucleic Acid Res. 21: 1259-1263, 1993.
52. RIABOWOL, K. T., VOSATKA, R. J., ZIFF, E. B., LAMP, N. J. AND FERAMISCO, J. R.: Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells. Mol. Cell. Biol. 8: 1670-1676, 1988.
53. RYDER, K., LANAHAN, A., PEREZ-ALBUERNE, E. AND NATHANS, D.: jun-D: a third member of the jun gene family. Proc. Natl. Acad. Sci. U.S.A. 86: 1500-1503, 1989.
54. RYDEH, K., LAU, L. F., AND NATHANS, D.: A gene activated by growth factors is related to the oncogene v-jun. Proc. Natl. Acad. Sci. U.S.A. 85: 1487-1491, 1988.
55. RYDER, K., AND NATHANS, D.: Induction of protooncogene c-jun by serum growth factors. Proc. Natl. Acad. Sci. U.S.A. 85: 8464-8467, 1988.
56. SOHLINGENSIEPEN, K.-H., SCHLINGENSIEPEN, R., KUNST, M., KLINGEH, I., GERDES, W., SEIFEHT, W. AND BRYSCH, W.: Opposite functions of jun B and c-jun in growth regulation in neuronal differentiation. Dev. Genet. 14: 305-312, 1993.
57. SCHÖLLER, H. R., HATZOPOULOS, A. K., BALLING, R., SUZUKI, N. AND GRUSS, P.: A family of octamer-specific proteins present during mouse embryogenesis: Evidence for germline-specific expression of an Oct factor. EMBO J. 8: 2543-2550, 1989.
58. SERAFINI, M. T., AROLA, L. AND ROMEU, A.: Glutathione and related enzyme activity in the 11-day rat embryo, placenta and perinatal liver. Biol. Neonate 60:236-242, 1991.
59. SLOTT, V. L. AND HALES, B. F.: Effect of glutathione depletion by buthionine sulfoximine on rat embryonic development in vitro. Biochem. Pharmacol. 36: 683-688, 1987.
60. SMEYNE, R. J., VENDRELL, M., HAYWARD, M., BAKER, S. J., MIAO, G. G., SCHILLING, K., ROBERTHON, L. M., CURRAN, T. AND MORGAN, J. I.: Continuous C-fos expression precedes programmed cell death in vivo. Nature (Lond) 363: 166-169, 1993.
61. SMITH, M. J. AND PHOCHOWNIK, E. V.: Inhibition of c-jun causes reversible proliferative arrest and withdrawal from the cell cycle. Blood 79: 2107-2115, 1992.
62. 1 mouse adrenocortical tumor cell line. Mol. Endocrinol. 4: 1144-1152, 1990.
63. TANIMURA, T. AND SHEPARD, T. H.: Glucose metabolism by rat embryos in vitro. Proc. Soc. Exp. Biol. Med. 135: 51-54, 1970.
64. TIETZE, F.: Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Anal. Biochem. 27: 502-522, 1969.
65. TOLEDANO, M. B. AND LEONARD, W. J.: Modulation of transcription factor NF-κB binding activity by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. U.S.A. 88:4328-4332, 1991.
66. TOWBIN, H., STAEHLIN, T. AND GORDON, J.: Electrophoretic transfer of proteins from acrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76: 4350-4354, 1979.
67. WANG, Z.-Q., OVITT, C., GRIGORIADIS, A. E., MÖHLE-STEINLEIN, U., RÜTHER, U. AND WAGNER, E. F.: Bone and haematopoeitic defects in mice lacking c-fos. Nature (Lond.) 360: 741-745, 1992.
68. WILKINSON, D. G., BHATI, S., RYSECK, R.-P. AND BRAVO, R.: Tissue-specific expression of c-jun and junB during organogenesis in the mouse. Development 106: 465-471, 1989.
69. WINS, L. AND WELLS, P. G.: Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: Evidence for reactive oxygen speciesmediated DNA oxidation in the molecular mechanism of phenytoin teratogenesis. Mol. Pharmacol. 48: 112-120, 1995.
70. WONG, M., HELSTON, L. M. J. AND WELLS, P. G.: Enhancement of murine phenytoin teratogenicity by the gamma-glutamylcysteine synthetase inhibitor L-buthionine-(S, R)-sulfoximine and by the glutathione depletor diethyl maleate. Teratology 40: 127-141, 1989.
71. WONG, M. AND WELLS, P. G.: Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1.3-bis(2-chloroethyl)-1-nitrosourea (BCNU). J. Pharmacol. Exp. Ther. 250: 336-342, 1989.