Fundamental aspects of reactive oxygen species, or what's the matter with oxygen?

Annals of the New York Academy of Sciences

Volumn 893, Issue , 1999, Pages 13-18

  Fridovich, Irwin ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; NUCLEIC ACID; PEROXIDASE; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

CELL DAMAGE; CONFERENCE PAPER; DEGENERATIVE DISEASE; HUMAN; OXIDATIVE STRESS; REDUCTION;

EID: 0033396970     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07814.x     Document Type: Conference Paper

References (16)

1. 1. Forman, L.J., P. Liu, R.G. Nagele & P.Y. Wong. 1998. Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat. Neurochem. Res. 23: 141-148.
2. 2. Mikawa, S., H. Kinouchi, H. Kamii, G.T. Gobbel, S.F. Chen, E. Carlson, C.J. Epstein & P.H. Chan. 1996. Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc superoxide dismutase transgenic mice. J. Neurosurg. 85: 885-891.
3. 3. Kihara, T., S. Sakata & M. Ikeda. 1995. Direct detection of ascorbyl radical in experimental brain injury: microdialysis and an electron spin resonance study. J. Neurochem. 65: 282-286.
4. 4. Cortopassi, G. & E. Wang. 1995. Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide, and cell death. Biochim. Biophys. Acta 1271: 171-176.
5. 5. Yang, C.S., P.J. Tsai, N.N. Lin, L. Liu & J.S. Kuo. 1995. Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat. Free Radic. Biol. Med. 19: 453-459.
6. 6. Moore, L.E. & R.J. Traystman. 1994. Role of oxygen free radicals and lipid peroxidation in cerebral reperfusion injury. Adv. Pharmacol. 31: 565-576.
7. 7. Gonzatez-Zulueta, M., L.M. Ensz, G. Mukhina, R.M. Lebovitz, R.M. Zwacka, J. F. Engelhardt, L.W. Oberley, V.L. Dawson & T.M. Dawson. 1998. Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity. J. Neurosci. 18: 2040-2055.
8. 8. Jordan, J., G.D. Ghadge, J.H. Prehn, P.T. Toth, R.P. Roos & R.J. Miller. 1995. Expression of human copper/zinc superoxide dismutase inhibits death of rat sympathetic neurons caused by withdrawal of nerve growth factor. Mol. Pharmacol. 47: 1095-1100.
9. 9. Nakao, N., E.M. Frodl, H. Widner, E. Carlson, F.A. Eggerding, C.J. Epstein & P. Brundin. 1995. Overexpressing Cu/Zn superoxide dismutase enhances the survival of transplanted neurons in a rat model of Parkinson's disease. Nature Med. 1: 226-231.
10. 10. Cheng, Y. & A.Y. Sun. 1994. Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons. Neurochem. Res. 19: 1557-1564.
11. 11. Bondy, S.C. & C.P. LeBel. 1993. The relationship between excitotoxicity and oxidative stress in the central nervous system. Free Radic. Biol. Med. 14: 633-642.
12. 12. Price, J.M., E.T. Sutton, A. Hellerman & T. Thomas. 1997. Beta amyloid induces cerebrovascular dysfunction in the rat brain. Neurol. Res. 19: 534-538.
13. 13. Gurney, M.E., F.B. Cutting, P. Zhai, P.K. Andrus & E.D. Hall. 1996. Pathogenic mechanisms in familial amyotrophic lateral sclerosis. Pathol. Biol. (Paris) 44: 51-56.
14. 14. Fridovich, I. 1998. An overview of oxy radicals in medical biology. Advan. Mol. Cell. Biol. 25: 1-14.
15. -), superoxide dismutases, and related matters. J. Biol. Chem. 272: 18515-18517.
16. 16. Hassan, H.M. 1997. Cytoxicity of oxy radicals and the evolution of superoxide dismutases. Lung Biol. Health Dis. 105: 27-47.